JP2019511497A5 - - Google Patents
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- JP2019511497A5 JP2019511497A5 JP2018548652A JP2018548652A JP2019511497A5 JP 2019511497 A5 JP2019511497 A5 JP 2019511497A5 JP 2018548652 A JP2018548652 A JP 2018548652A JP 2018548652 A JP2018548652 A JP 2018548652A JP 2019511497 A5 JP2019511497 A5 JP 2019511497A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- aryl
- heteroaryl
- heteroarylalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662309330P | 2016-03-16 | 2016-03-16 | |
| US62/309,330 | 2016-03-16 | ||
| US201662416058P | 2016-11-01 | 2016-11-01 | |
| US62/416,058 | 2016-11-01 | ||
| PCT/US2017/022791 WO2017161174A1 (en) | 2016-03-16 | 2017-03-16 | Extended release conjugates of exenatide analogs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019511497A JP2019511497A (ja) | 2019-04-25 |
| JP2019511497A5 true JP2019511497A5 (https=) | 2020-04-30 |
| JP7017248B2 JP7017248B2 (ja) | 2022-02-08 |
Family
ID=59852218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018548652A Expired - Fee Related JP7017248B2 (ja) | 2016-03-16 | 2017-03-16 | エキセナチド類似体の持続放出コンジュゲート |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20200164083A1 (https=) |
| EP (2) | EP3429608A4 (https=) |
| JP (1) | JP7017248B2 (https=) |
| KR (1) | KR20180129825A (https=) |
| CN (1) | CN109414469A (https=) |
| AU (2) | AU2017234680A1 (https=) |
| BR (1) | BR112018068639A2 (https=) |
| CA (1) | CA3016814A1 (https=) |
| MX (1) | MX2018011149A (https=) |
| RU (1) | RU2764547C2 (https=) |
| SG (1) | SG11201807832VA (https=) |
| WO (1) | WO2017161174A1 (https=) |
| ZA (2) | ZA201805953B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10745456B2 (en) * | 2015-04-01 | 2020-08-18 | The Scripps Research Institute | Methods and compositions related to GPCR agonist polypeptides |
| JOP20190245A1 (ar) | 2017-04-20 | 2019-10-15 | Novartis Ag | أنظمة توصيل إطلاق مستدام تتضمن روابط بلا أثر لنقطة الربط |
| TW202027794A (zh) | 2018-10-03 | 2020-08-01 | 瑞士商諾華公司 | 血管生成素樣３多肽之持續遞送 |
| CN119970617A (zh) | 2019-04-05 | 2025-05-13 | 普罗林科斯有限责任公司 | 改良偶联接头 |
| MX2022001528A (es) * | 2019-08-07 | 2022-03-11 | Prolynx Llc | Esterilizacion con vapor de hidrogeles reticulados por enlazadores beta-eliminativos. |
| WO2022115563A1 (en) * | 2020-11-25 | 2022-06-02 | Prolynx Llc | Extended release hydrogel conjugates of c-natriuretic peptides |
| AU2022205377A1 (en) | 2021-01-08 | 2023-07-20 | Cellanome, Inc. | Devices and methods for analyzing biological samples |
| US12576400B2 (en) | 2021-01-08 | 2026-03-17 | Cellanome, Inc. | Methods for incubating and analyzing a cell in a compartment of a fluidic device |
| WO2025128916A1 (en) * | 2023-12-13 | 2025-06-19 | Cellanome, Inc. | Devices and methods for analyzing biological samples |
| KR102716759B1 (ko) | 2023-12-20 | 2024-10-15 | (주)인벤티지랩 | 엑세나타이드를 포함하는 서방형 주사제 조성물 및 이의 제조 방법 |
| WO2026020143A1 (en) * | 2024-07-19 | 2026-01-22 | Prolynx Llc | Extended-release conjugates of lipidated peptides, and uses thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2278589T3 (es) * | 1999-01-14 | 2007-08-16 | Amylin Pharmaceuticals, Inc. | Excendinas destinadas a la inhibicion de glucagon. |
| JP2006501820A (ja) * | 2002-09-06 | 2006-01-19 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | 修飾ｇｌｐ−１受容体アゴニストおよびそれらの薬理学的使用法 |
| BR0314996A (pt) * | 2002-10-02 | 2005-08-09 | Zealand Pharma As | Composição, composição farmaceuticamente aceitável, método para produzir a composição, métodos para estabilizar a exendina-4 (1-39) ou uma sua variante, derivado ou análogo contra a degradação, antes, durante ou após o uso pretendido, para tratar doenças, para tratar de estados de doenças associados com nìveis elevados de glicose do sangue, para a regulação dos nìveis de glicose do sangue, para a regulação do esvaziamento gástrico, para estimular a liberação de insulina em um mamìfero para reduzir o nìvel de glicose do sangue em um mamìfero, para reduzir o nìvel de lipìdeos plasmáticos em um mamìfero, para reduzir a mortalidade e a morbidez após o infarto miocárdico em um mamìfero, para estimular a liberação de insulina em um mamìfero, e para produzir uma exendina (1-39) estabilizada, e, exendina (1-39) estabilizada |
| CN100540565C (zh) * | 2005-01-14 | 2009-09-16 | 无锡宏创医药科技有限公司 | 修饰的Exendins及其应用 |
| GB2427360A (en) | 2005-06-22 | 2006-12-27 | Complex Biosystems Gmbh | Aliphatic prodrug linker |
| CN101125207B (zh) * | 2006-11-14 | 2012-09-05 | 上海华谊生物技术有限公司 | 带有聚乙二醇基团的艾塞丁或其类似物及其制剂和用途 |
| WO2008116294A1 (en) * | 2007-03-23 | 2008-10-02 | Matregen Corp. | Exendin analogs |
| ES2672526T3 (es) | 2008-06-26 | 2018-06-14 | Prolynx Llc | Profármacos y conjugados de fármaco-macromolécula que presentan velocidades de liberación de fármaco controladas |
| WO2010017215A2 (en) * | 2008-08-04 | 2010-02-11 | The Regents Of The University Of California | Biodegradable microspheres and methods of use thereof |
| PT3345593T (pt) * | 2009-11-13 | 2023-11-27 | Sanofi Aventis Deutschland | Composição farmacêutica compreendendo despro36exendina- 4(1-39)-lys6-nh2 e metionina |
| ES2584381T3 (es) | 2010-05-05 | 2016-09-27 | Prolynx Llc | Liberación controlada de compuestos activos desde conjugados macromoleculares |
| US8703907B2 (en) | 2010-05-05 | 2014-04-22 | Prolynx Llc | Controlled drug release from dendrimers |
| EP2566334B1 (en) * | 2010-05-05 | 2018-04-18 | Prolynx, LLC | Controlled drug release from solid supports |
| WO2011156407A2 (en) * | 2010-06-09 | 2011-12-15 | Amylin Pharmaceuticals, Inc. | Glp-1 receptor agonists to treat pancre-atitis |
| CA2848142C (en) | 2011-09-07 | 2021-05-18 | Prolynx Llc | Hydrogels with biodegradable crosslinking |
| US20140256626A1 (en) * | 2011-10-18 | 2014-09-11 | Prolynx Llc | Peg conjugates of exenatide |
-
2017
- 2017-03-16 KR KR1020187029780A patent/KR20180129825A/ko not_active Abandoned
- 2017-03-16 JP JP2018548652A patent/JP7017248B2/ja not_active Expired - Fee Related
- 2017-03-16 CA CA3016814A patent/CA3016814A1/en active Pending
- 2017-03-16 EP EP17767565.9A patent/EP3429608A4/en not_active Withdrawn
- 2017-03-16 RU RU2018136200A patent/RU2764547C2/ru active
- 2017-03-16 AU AU2017234680A patent/AU2017234680A1/en not_active Abandoned
- 2017-03-16 SG SG11201807832VA patent/SG11201807832VA/en unknown
- 2017-03-16 BR BR112018068639A patent/BR112018068639A2/pt not_active IP Right Cessation
- 2017-03-16 CN CN201780018057.6A patent/CN109414469A/zh active Pending
- 2017-03-16 EP EP21189671.7A patent/EP3922269A1/en not_active Withdrawn
- 2017-03-16 WO PCT/US2017/022791 patent/WO2017161174A1/en not_active Ceased
- 2017-03-16 US US16/085,139 patent/US20200164083A1/en not_active Abandoned
- 2017-03-16 MX MX2018011149A patent/MX2018011149A/es unknown
-
2018
- 2018-09-05 ZA ZA201805953A patent/ZA201805953B/en unknown
-
2019
- 2019-09-02 ZA ZA2019/05787A patent/ZA201905787B/en unknown
-
2021
- 2021-09-17 AU AU2021232810A patent/AU2021232810A1/en not_active Abandoned
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