JP2019511468A5 - - Google Patents
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- Publication number
- JP2019511468A5 JP2019511468A5 JP2018542712A JP2018542712A JP2019511468A5 JP 2019511468 A5 JP2019511468 A5 JP 2019511468A5 JP 2018542712 A JP2018542712 A JP 2018542712A JP 2018542712 A JP2018542712 A JP 2018542712A JP 2019511468 A5 JP2019511468 A5 JP 2019511468A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- wound
- chronic non
- healing
- effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010052428 Wound Diseases 0.000 claims description 51
- 208000027418 Wounds and injury Diseases 0.000 claims description 51
- 230000001684 chronic effect Effects 0.000 claims description 34
- 230000035876 healing Effects 0.000 claims description 34
- 239000008194 pharmaceutical composition Substances 0.000 claims description 34
- 239000000017 hydrogel Substances 0.000 claims description 13
- 239000012620 biological material Substances 0.000 claims description 12
- 239000012530 fluid Substances 0.000 claims description 5
- 206010063560 Excessive granulation tissue Diseases 0.000 claims description 3
- 210000001126 granulation tissue Anatomy 0.000 claims description 3
- 230000002757 inflammatory effect Effects 0.000 claims description 3
- 102000008186 Collagen Human genes 0.000 claims description 2
- 108010035532 Collagen Proteins 0.000 claims description 2
- 206010029113 Neovascularisation Diseases 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 229920001436 collagen Polymers 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 claims description 2
- 244000005700 microbiome Species 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 238000003786 synthesis reaction Methods 0.000 claims description 2
- 230000029663 wound healing Effects 0.000 claims description 2
- 239000000463 material Substances 0.000 claims 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 102000018233 Fibroblast Growth Factor Human genes 0.000 claims 2
- 108050007372 Fibroblast Growth Factor Proteins 0.000 claims 2
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 2
- 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 claims 2
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 claims 2
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 claims 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims 2
- 230000002924 anti-infective effect Effects 0.000 claims 2
- 229940126864 fibroblast growth factor Drugs 0.000 claims 2
- 239000003102 growth factor Substances 0.000 claims 2
- 239000008213 purified water Substances 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 claims 1
- 208000002874 Acne Vulgaris Diseases 0.000 claims 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010030113 Oedema Diseases 0.000 claims 1
- 208000004210 Pressure Ulcer Diseases 0.000 claims 1
- 208000002847 Surgical Wound Diseases 0.000 claims 1
- 208000025865 Ulcer Diseases 0.000 claims 1
- 206010000496 acne Diseases 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 229960000458 allantoin Drugs 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 239000000416 hydrocolloid Substances 0.000 claims 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
- 230000001338 necrotic effect Effects 0.000 claims 1
- 239000001540 sodium lactate Substances 0.000 claims 1
- 229940005581 sodium lactate Drugs 0.000 claims 1
- 235000011088 sodium lactate Nutrition 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 231100000397 ulcer Toxicity 0.000 claims 1
- 238000000034 method Methods 0.000 description 14
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662292384P | 2016-02-08 | 2016-02-08 | |
| US62/292,384 | 2016-02-08 | ||
| PCT/US2017/017044 WO2017139398A1 (en) | 2016-02-08 | 2017-02-08 | Compositions and methods for treating chronic wounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019511468A JP2019511468A (ja) | 2019-04-25 |
| JP2019511468A5 true JP2019511468A5 (https=) | 2021-09-30 |
| JP7026050B2 JP7026050B2 (ja) | 2022-02-25 |
Family
ID=59563381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018542712A Active JP7026050B2 (ja) | 2016-02-08 | 2017-02-08 | 慢性創傷を治療するための組成物及び方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20190046547A1 (https=) |
| EP (1) | EP3413881B1 (https=) |
| JP (1) | JP7026050B2 (https=) |
| AU (1) | AU2017217527A1 (https=) |
| BR (1) | BR112018016004A2 (https=) |
| CA (1) | CA3013349A1 (https=) |
| CL (1) | CL2018002128A1 (https=) |
| CO (1) | CO2018008856A2 (https=) |
| ES (1) | ES2883147T3 (https=) |
| IL (1) | IL261010B (https=) |
| WO (1) | WO2017139398A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL256312A (en) | 2017-12-14 | 2018-01-31 | Omrix Biopharmaceuticals Ltd | Antibacterial preparations containing minocycline and oxidized cellulose |
| CN111228561A (zh) * | 2020-01-13 | 2020-06-05 | 张新华 | 一种含中药基质的免涂抹创面敷料 |
| AU2021325682A1 (en) * | 2020-08-10 | 2023-03-02 | Gel4Med, Inc. | Antimicrobial matrix formed from peptide hydrogels |
| DE102020134827A1 (de) * | 2020-12-23 | 2022-06-23 | Paul Hartmann Ag | Hydrogel zur Behandlung von Druckgeschwüren |
| AU2022220628A1 (en) * | 2021-02-12 | 2023-09-07 | Beth Israel Deaconess Medical Center | Shape memory adhesive materials for diabetic wound healing |
| CN115040773B (zh) * | 2022-06-22 | 2023-10-13 | 西南交通大学 | 一种治疗慢性感染创面的微针贴片及其制备方法和应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4401651A (en) * | 1979-04-18 | 1983-08-30 | Knutson Richard A | Wound-healing compositions containing povidone-iodine |
| JPS6249848A (ja) * | 1985-08-30 | 1987-03-04 | 三金工業株式会社 | 口腔内装着物 |
| US5967979A (en) * | 1995-11-14 | 1999-10-19 | Verg, Inc. | Method and apparatus for photogrammetric assessment of biological tissue |
| DE10031741A1 (de) * | 2000-06-29 | 2002-01-17 | Sanguibio Tech Ag | Einen Sauerstoffträger, ausgewählt aus Hämoglobin oder Hämoglobin- und Myoglobin-enthaltende Zubereitung als Externum zur natürlichen Regeneration der Haut bei Sauerstoff-Mangel |
| KR100978905B1 (ko) * | 2002-03-14 | 2010-08-31 | 가부시키가이샤 메드렉스 | 창상용 외용제 |
| EP1576368B1 (en) * | 2002-12-23 | 2009-02-18 | William Marsh Rice Univeristy | Methods and compositions for enhancing fibrocyte formation |
| US7731993B2 (en) * | 2004-11-17 | 2010-06-08 | Lindsey Berkson | Composition for treating a dermal anomaly |
| US8440617B2 (en) * | 2007-03-22 | 2013-05-14 | The Trustees Of The University Of Pennsylvania | Hyperbaric treatment in wound healing |
| DE102008031183A1 (de) * | 2008-07-03 | 2010-01-07 | Paul Hartmann Ag | Wundauflage |
| EP2226073A1 (en) * | 2009-03-02 | 2010-09-08 | Euro-Celtique S.A. | Topical pharmaceutical composition comprising an antiseptic and arginine for wound healing |
| US20110171284A1 (en) * | 2010-01-11 | 2011-07-14 | Gilman Miles E | Povidone-iodine and sucrose wound healing dressing |
| US20130209592A1 (en) * | 2012-02-13 | 2013-08-15 | Steven C. Denstman | Plant Extract Based Compositions and Methods For Treating Chronic Wounds |
| WO2014150174A1 (en) * | 2013-03-15 | 2014-09-25 | Mccord Darlene E | Methods for improved wound closure employing olivamine and human umbilical vein endothelial cells |
| DE102013018565A1 (de) * | 2013-10-28 | 2015-04-30 | Gmbu E.V., Fachsektion Dresden | Körperpflegemittel und dessen Verwendung |
-
2017
- 2017-02-08 BR BR112018016004A patent/BR112018016004A2/pt not_active IP Right Cessation
- 2017-02-08 ES ES17750709T patent/ES2883147T3/es active Active
- 2017-02-08 CA CA3013349A patent/CA3013349A1/en active Pending
- 2017-02-08 JP JP2018542712A patent/JP7026050B2/ja active Active
- 2017-02-08 AU AU2017217527A patent/AU2017217527A1/en not_active Abandoned
- 2017-02-08 US US16/076,577 patent/US20190046547A1/en active Pending
- 2017-02-08 WO PCT/US2017/017044 patent/WO2017139398A1/en not_active Ceased
- 2017-02-08 EP EP17750709.2A patent/EP3413881B1/en active Active
-
2018
- 2018-08-06 IL IL261010A patent/IL261010B/en unknown
- 2018-08-07 CL CL2018002128A patent/CL2018002128A1/es unknown
- 2018-08-24 CO CONC2018/0008856A patent/CO2018008856A2/es unknown
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