JP2019509748A5 - - Google Patents

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Publication number
JP2019509748A5
JP2019509748A5 JP2018550831A JP2018550831A JP2019509748A5 JP 2019509748 A5 JP2019509748 A5 JP 2019509748A5 JP 2018550831 A JP2018550831 A JP 2018550831A JP 2018550831 A JP2018550831 A JP 2018550831A JP 2019509748 A5 JP2019509748 A5 JP 2019509748A5
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JP
Japan
Prior art keywords
factor
fine
nucleic acid
heterologous nucleic
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2018550831A
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English (en)
Japanese (ja)
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JP2019509748A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/024951 external-priority patent/WO2017173043A1/en
Publication of JP2019509748A publication Critical patent/JP2019509748A/ja
Publication of JP2019509748A5 publication Critical patent/JP2019509748A5/ja
Priority to JP2022070121A priority Critical patent/JP2022101642A/ja
Priority to JP2025019374A priority patent/JP2025087704A/ja
Withdrawn legal-status Critical Current

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JP2018550831A 2016-03-30 2017-03-30 組換えタンパク質及び/又はウイルスベクター製造のための細胞株 Withdrawn JP2019509748A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022070121A JP2022101642A (ja) 2016-03-30 2022-04-21 組換えタンパク質及び/又はウイルスベクター製造のための細胞株
JP2025019374A JP2025087704A (ja) 2016-03-30 2025-02-07 組換えタンパク質及び/又はウイルスベクター製造のための細胞株

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662315480P 2016-03-30 2016-03-30
US62/315,480 2016-03-30
PCT/US2017/024951 WO2017173043A1 (en) 2016-03-30 2017-03-30 Cell line for recombinant protein and/or viral vector production

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022070121A Division JP2022101642A (ja) 2016-03-30 2022-04-21 組換えタンパク質及び/又はウイルスベクター製造のための細胞株

Publications (2)

Publication Number Publication Date
JP2019509748A JP2019509748A (ja) 2019-04-11
JP2019509748A5 true JP2019509748A5 (enExample) 2020-04-09

Family

ID=59966430

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018550831A Withdrawn JP2019509748A (ja) 2016-03-30 2017-03-30 組換えタンパク質及び/又はウイルスベクター製造のための細胞株
JP2022070121A Pending JP2022101642A (ja) 2016-03-30 2022-04-21 組換えタンパク質及び/又はウイルスベクター製造のための細胞株
JP2025019374A Pending JP2025087704A (ja) 2016-03-30 2025-02-07 組換えタンパク質及び/又はウイルスベクター製造のための細胞株

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022070121A Pending JP2022101642A (ja) 2016-03-30 2022-04-21 組換えタンパク質及び/又はウイルスベクター製造のための細胞株
JP2025019374A Pending JP2025087704A (ja) 2016-03-30 2025-02-07 組換えタンパク質及び/又はウイルスベクター製造のための細胞株

Country Status (11)

Country Link
US (1) US20190078099A1 (enExample)
EP (1) EP3436576A4 (enExample)
JP (3) JP2019509748A (enExample)
KR (1) KR102479894B1 (enExample)
CN (1) CN109563496B (enExample)
AU (2) AU2017244133A1 (enExample)
BR (1) BR112018070250A2 (enExample)
CA (1) CA3019126A1 (enExample)
MX (1) MX2018011928A (enExample)
SG (1) SG11201808398PA (enExample)
WO (1) WO2017173043A1 (enExample)

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EP3215191B1 (en) 2014-11-05 2024-08-14 Voyager Therapeutics, Inc. Aadc polynucleotides for the treatment of parkinson's disease
KR20230145206A (ko) 2014-11-14 2023-10-17 보이저 테라퓨틱스, 인크. 조절성 폴리뉴클레오티드
CN114717264A (zh) 2014-11-14 2022-07-08 沃雅戈治疗公司 治疗肌萎缩性侧索硬化(als)的组合物和方法
US11697825B2 (en) 2014-12-12 2023-07-11 Voyager Therapeutics, Inc. Compositions and methods for the production of scAAV
US10584337B2 (en) 2016-05-18 2020-03-10 Voyager Therapeutics, Inc. Modulatory polynucleotides
KR20200018488A (ko) 2017-05-24 2020-02-19 토리스 게엠베하 고암모니아혈증을 치료하기 위한 글루타민 합성효소의 용도
JOP20190269A1 (ar) 2017-06-15 2019-11-20 Voyager Therapeutics Inc بولي نوكليوتيدات aadc لعلاج مرض باركنسون
JP2020525003A (ja) * 2017-06-21 2020-08-27 バートナム,ティモシー,エー. 腎臓病治療のための免疫特権を有する生物活性腎細胞
MX2020004035A (es) 2017-10-20 2020-11-09 Res Inst Nationwide Childrens Hospital Métodos y materiales para terapia génica con nt-3.
CN112424359A (zh) 2018-05-15 2021-02-26 沃雅戈治疗公司 用于治疗帕金森氏病的组合物和方法
WO2020012446A1 (en) * 2018-07-13 2020-01-16 Enzene Biosciences Limited Double knock-out cho cell line method of its generation and producing therapeutic proteins therefrom
US12281321B2 (en) 2018-09-28 2025-04-22 Voyager Therapeutics, Inc. Frataxin expression constructs having engineered promoters and methods of use thereof
AU2019354296A1 (en) * 2018-10-01 2021-04-29 Ultragenyx Pharmaceutical Inc. Gene therapy for treating propionic acidemia
US12686874B2 (en) 2020-03-31 2026-07-21 Ultragenyx Pharmaceutical Inc. Gene therapy for treating propionic acidemia
US12054738B2 (en) 2020-07-30 2024-08-06 Shape Therapeutics Inc. Stable cell lines for inducible production of rAAV virions
EP4269570A4 (en) * 2020-12-25 2025-04-30 Agc Inc. Viral vector-producing cells with improved vector-producing capacity, methods for producing the same, and methods for selecting them
EP4301861A1 (en) 2021-03-03 2024-01-10 Shape Therapeutics Inc. Auxotrophic cells for virus production and compositions and methods of making
AR127674A1 (es) 2021-10-18 2024-02-21 Regeneron Pharma Células de mamífero que comprenden genes cas9 integrados para producir sitios de integración estables, y células de mamífero que comprenden sitios de integración estables y otros sitios
JP2024537896A (ja) 2021-10-18 2024-10-16 リジェネロン・ファーマシューティカルズ・インコーポレイテッド アデノウイルス随伴ウイルスポリヌクレオチドを含む真核細胞
WO2023150506A2 (en) * 2022-02-01 2023-08-10 Shape Therapeutics Inc. STABLE CELL LINES FOR INDUCIBLE PRODUCTION OF rAAV VIRIONS
EP4514844A1 (en) 2022-04-29 2025-03-05 Broadwing Bio LLC Complement factor h related 4-specific antibodies and uses thereof
CN119487063A (zh) 2022-04-29 2025-02-18 博闻生物有限责任公司 双特异性抗体以及治疗眼部疾病的方法
AU2023259251A1 (en) 2022-04-29 2024-11-14 Broadwing Bio, Inc. Angiopoietin-related protein 7-specific antibodies and uses thereof
WO2024227154A1 (en) 2023-04-28 2024-10-31 Broadwing Bio Llc Complement component 3 (c3)-specific antibodies and uses thereof
CN122349567A (zh) 2023-12-11 2026-07-07 济世易为生物有限公司 利用反式剪接和拆分型选择标记的蛋白质表达

Family Cites Families (9)

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US20080001001A1 (en) * 2006-04-17 2008-01-03 Pevnick Stephen H Pneumatic Activated Fountain
WO2007136685A2 (en) * 2006-05-19 2007-11-29 Sangamo Biosciences, Inc. Methods and compositions for inactivation of dihydrofolate reductase
JP5756016B2 (ja) * 2008-10-29 2015-07-29 サンガモ バイオサイエンシーズ, インコーポレイテッド グルタミンシンセターゼ遺伝子の発現を不活性化する方法及び組成物
AU2015201300A1 (en) * 2008-10-29 2015-04-02 Sangamo Therapeutics, Inc. Methods and Compositions For Inactivating Glutamine Synthetase Gene Expression
EP3683319A1 (en) * 2011-06-01 2020-07-22 Precision Biosciences, Inc. Methods and products for producing engineered mammalian cell lines with amplified transgenes
BR112014020325A2 (pt) * 2012-02-17 2017-08-08 Childrens Hospital Philadelphia composições de vetor do aav e métodos para a transferência de gene para as células, órgãos e tecidos
PT2970920T (pt) * 2013-03-15 2018-07-30 Childrens Hospital Philadelphia Processo de fabrico escalável para produzir vetores lentivirais recombinantes em sistema de cultura de células de suspensão livres de soro
NZ716102A (en) * 2013-07-22 2021-12-24 The Children’S Hospital Of Philadelphia Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues
KR20170081784A (ko) * 2016-01-04 2017-07-13 한국과학기술원 Gs 유전자가 결핍된 신규한 hek293 세포주 및 상기 형질전환된 hek293 숙주세포를 이용한 목적 단백질의 생산 방법

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