JP2019509014A5 - - Google Patents

Download PDF

Info

Publication number
JP2019509014A5
JP2019509014A5 JP2018526708A JP2018526708A JP2019509014A5 JP 2019509014 A5 JP2019509014 A5 JP 2019509014A5 JP 2018526708 A JP2018526708 A JP 2018526708A JP 2018526708 A JP2018526708 A JP 2018526708A JP 2019509014 A5 JP2019509014 A5 JP 2019509014A5
Authority
JP
Japan
Prior art keywords
antibody
polypeptide
binding
human
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018526708A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019509014A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2016/078395 external-priority patent/WO2017089334A1/en
Publication of JP2019509014A publication Critical patent/JP2019509014A/ja
Publication of JP2019509014A5 publication Critical patent/JP2019509014A5/ja
Pending legal-status Critical Current

Links

JP2018526708A 2015-11-23 2016-11-22 Cd39血管アイソフォームターゲティング剤 Pending JP2019509014A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201562258701P 2015-11-23 2015-11-23
US62/258,701 2015-11-23
US201562263760P 2015-12-07 2015-12-07
US62/263,760 2015-12-07
US201562267343P 2015-12-15 2015-12-15
US62/267,343 2015-12-15
US201662320738P 2016-04-11 2016-04-11
US62/320,738 2016-04-11
US201662404779P 2016-10-06 2016-10-06
US62/404,779 2016-10-06
PCT/EP2016/078395 WO2017089334A1 (en) 2015-11-23 2016-11-22 Cd39 vascular isoform targeting agents

Publications (2)

Publication Number Publication Date
JP2019509014A JP2019509014A (ja) 2019-04-04
JP2019509014A5 true JP2019509014A5 (enExample) 2019-12-12

Family

ID=57391960

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018526708A Pending JP2019509014A (ja) 2015-11-23 2016-11-22 Cd39血管アイソフォームターゲティング剤

Country Status (6)

Country Link
US (1) US20190153113A1 (enExample)
EP (1) EP3380519A1 (enExample)
JP (1) JP2019509014A (enExample)
AU (1) AU2016359790A1 (enExample)
CA (1) CA3005986A1 (enExample)
WO (1) WO2017089334A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3153526B1 (en) 2008-01-31 2020-09-23 INSERM - Institut National de la Santé et de la Recherche Médicale Antibodies against human cd39 and use thereof for inhibiting t regulatory cells activity
KR102379464B1 (ko) 2016-06-20 2022-03-29 키맵 리미티드 항-pd-l1 항체
AU2018235092B2 (en) 2017-03-16 2024-09-19 Innate Pharma Compositions and methods for treating cancer
US12226479B2 (en) 2017-05-11 2025-02-18 The General Hospital Corporation Methods and compositions of use of CD8+ tumor infiltrating lymphocyte subtypes and gene signatures thereof
SG11202000820PA (en) * 2017-07-31 2020-02-27 Tizona Therapeutics Anti-cd39 antibodies, compositions comprising anti-cd39 antibodies and methods of using anti-cd39 antibodies
AU2018346447B2 (en) * 2017-10-06 2025-06-19 Innate Pharma Restoration of T cell activity via the CD39/CD73 axis
IL273440B1 (en) * 2017-11-15 2026-08-01 Innate Pharma Strengthening the effect of ATP release
JP7800852B2 (ja) * 2018-01-10 2026-01-16 バイオインヴェント インターナショナル アーベー 抗体の新規組み合わせおよびその使用
CN112074541A (zh) 2018-05-03 2020-12-11 上海岸迈生物科技有限公司 Pd-1和lag-3的高亲和力抗体以及由其制备的双特异性结合蛋白
UY38247A (es) 2018-05-30 2019-12-31 Novartis Ag Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
EP3806902A4 (en) * 2018-06-14 2022-05-04 Beth Israel Deaconess Medical Center, Inc. COMPOSITIONS AND METHODS TO PREVENT OR REVERSE T-CELL DEPLETION BY ECTONUCLEOTIDASE INHIBITION AND ANTIBODY-MEDIATED TARGET CYTOSIS
TWI870353B (zh) 2018-06-18 2025-01-21 法商天賜製藥公司 用於治療癌症之組合物及方法
WO2020146795A1 (en) 2019-01-11 2020-07-16 Omeros Corporation Methods and compositions for treating cancer
ES3070946T3 (en) 2019-03-12 2026-06-18 Arcus Biosciences Inc Treatment of an oncogenene driven cancer having a kras or egfr mutation by decreasing adenosine production or antagonizing adenosine activation
CA3135487A1 (en) 2019-03-29 2020-10-08 Arcus Biosciences, Inc. Treatment of cancer utilizing an identified adenosine fingerprint
KR20220002959A (ko) 2019-04-23 2022-01-07 이나뜨 파르마 에스.에이. Cd73 차단 항체
CN114127121B (zh) 2019-08-12 2025-04-11 北京恩瑞尼生物科技股份有限公司 用于通过cd39表达细胞的adcc靶向促进和增强t细胞介导的免疫反应的方法和组合物
KR20220050971A (ko) * 2019-08-27 2022-04-25 엘피사이언스 (쑤저우) 바이오파마, 엘티디. 신규 항-cd39 항체
KR20220062500A (ko) 2019-09-16 2022-05-17 서피스 온콜로지, 인크. 항-cd39 항체 조성물 및 방법
CN110407941B (zh) * 2019-09-25 2020-01-14 上海岸迈生物科技有限公司 Cd39的高亲和力抗体及其用途
US12391756B2 (en) 2019-11-05 2025-08-19 Jacobio Pharmaceuticals Co., Ltd. Binding molecule specific for CD39 and use thereof
TW202307006A (zh) * 2021-06-03 2023-02-16 美商表面腫瘤學公司 用抗cd39抗體及派姆單抗治療癌症之方法
TW202340243A (zh) * 2022-03-03 2023-10-16 美商阿克思生物科學有限公司 抗cd39抗體及其用途
CA3248580A1 (en) 2022-04-29 2023-11-02 Purinomia Biotech, Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASES AND DISORDERS CAUSED BY EOSINOPHIL ACTIVITY
WO2024115935A1 (en) * 2022-11-29 2024-06-06 Inserm Methods for the treatment of b-cell lymphoma using cd39 inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3153526B1 (en) * 2008-01-31 2020-09-23 INSERM - Institut National de la Santé et de la Recherche Médicale Antibodies against human cd39 and use thereof for inhibiting t regulatory cells activity
WO2012085132A1 (en) * 2010-12-22 2012-06-28 Orega Biotech Antibodies against human cd39 and use thereof
ES2929575T3 (es) * 2011-06-06 2022-11-30 Novo Nordisk As Anticuerpos terapéuticos

Similar Documents

Publication Publication Date Title
ES3038421T3 (en) Humanized or chimeric cd3 antibodies
US12227569B2 (en) Humanized antibodies with increased stability
CN109715663B (zh) 结合生长抑素受体2的异源二聚抗体
CN101952454B (zh) 具有减弱的Fc配体亲和性的抗IFNAR1抗体
RU2013125459A (ru) АНТИТЕЛА ПРОТИВ БЕЛКА РЕЦЕПТОРА c-Met
JP2013545455A5 (enExample)
JP2014520788A5 (enExample)
US11299551B2 (en) Composite binding molecules targeting immunosuppressive B cells
CN112334486B (zh) 用于治疗癌症的组合物和方法
JP2018506277A5 (enExample)
TW202509068A (zh) 結合ox40l之抗體及使用方法
EP4417626A1 (en) Novel antibody-cytokine fusion protein, preparation method therefor and use thereof
US20240352156A1 (en) Antibodies targeting immunosuppressive b cells
JP2023076596A5 (enExample)
RU2019123112A (ru) Анти-il-5 антитела
CA3146977A1 (en) Antibody constructs binding 4-1bb and folate receptor alpha and uses thereof
RU2015129655A (ru) Антитело человека, специфичное к матапневмовирусу человека, или антиген-связывающий фрагмент указанного антитела
JP2023511652A (ja) 鎖間システインが選択的にマッチングされた二重特異性抗体及びその使用
CN118139639A (zh) 治疗与免疫抑制b细胞相关联的癌症的方法
CN110709417A (zh) 具有突变人IgG4的多肽
AU2017365367A1 (en) Monoclonal antibody directed to FGFR1
KR20210116429A (ko) 이중특이적 항-cd37 항체를 포함하는 제약 조성물
WO2018095932A1 (en) Monoclonal antibody directed to fgfr1
CN121443643A (zh) 基于沉默抗体的抗met构建体用于治疗肿瘤和转移
JP2019517813A5 (enExample)