JP2019505538A5 - - Google Patents

Info

Publication number

JP2019505538A5

JP2019505538A5 JP2018542227A JP2018542227A JP2019505538A5 JP 2019505538 A5 JP2019505538 A5 JP 2019505538A5 JP 2018542227 A JP2018542227 A JP 2018542227A JP 2018542227 A JP2018542227 A JP 2018542227A JP 2019505538 A5 JP2019505538 A5 JP 2019505538A5

Authority

JP

Japan

Prior art keywords

composition

carrier solution

carrageenan

amount

kappa

Prior art date

2017-02-17

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 239000000243 solution Substances 0.000 claims 12
• 239000000203 mixture Substances 0.000 claims 10
• ZNOZWUKQPJXOIG-XSBHQQIPSA-L [(2r,3s,4r,5r,6s)-6-[[(1r,3s,4r,5r,8s)-3,4-dihydroxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-4-[[(1r,3r,4r,5r,8s)-8-[(2s,3r,4r,5r,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-sulfonatooxyoxan-2-yl]oxy-4-hydroxy-2,6-dioxabicyclo[3.2.1]octan-3-yl]oxy]-5-hydroxy-2-( Chemical compound O[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H]2OC[C@H]1O[C@H](O[C@H]1[C@H]([C@@H](CO)O[C@@H](O[C@@H]3[C@@H]4OC[C@H]3O[C@H](O)[C@@H]4O)[C@@H]1O)OS([O-])(=O)=O)[C@@H]2O ZNOZWUKQPJXOIG-XSBHQQIPSA-L 0.000 claims 7
• 239000013543 active substance Substances 0.000 claims 4
• FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
• TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 2
• 230000000172 allergic effect Effects 0.000 claims 2
• 239000003242 anti bacterial agent Substances 0.000 claims 2
• 230000000843 anti-fungal effect Effects 0.000 claims 2
• 230000003110 anti-inflammatory effect Effects 0.000 claims 2
• 230000000840 anti-viral effect Effects 0.000 claims 2
• 229940121375 antifungal agent Drugs 0.000 claims 2
• 239000003963 antioxidant agent Substances 0.000 claims 2
• 230000003078 antioxidant effect Effects 0.000 claims 2
• 208000010668 atopic eczema Diseases 0.000 claims 2
• 230000003115 biocidal effect Effects 0.000 claims 2
• 201000010099 disease Diseases 0.000 claims 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
• HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 2
• 239000000811 xylitol Substances 0.000 claims 2
• 229960002675 xylitol Drugs 0.000 claims 2
• 235000010447 xylitol Nutrition 0.000 claims 2
• HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 2
• 206010001076 Acute sinusitis Diseases 0.000 claims 1
• 239000004386 Erythritol Substances 0.000 claims 1
• UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims 1
• WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
• 206010039085 Rhinitis allergic Diseases 0.000 claims 1
• UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims 1
• 201000010105 allergic rhinitis Diseases 0.000 claims 1
• WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
• 229940057801 calcium lactate pentahydrate Drugs 0.000 claims 1
• JCFHGKRSYPTRSS-UHFFFAOYSA-N calcium;2-hydroxypropanoic acid;hydrate Chemical compound O.[Ca].CC(O)C(O)=O JCFHGKRSYPTRSS-UHFFFAOYSA-N 0.000 claims 1
• 239000000679 carrageenan Substances 0.000 claims 1
• 229940113118 carrageenan Drugs 0.000 claims 1
• 235000010418 carrageenan Nutrition 0.000 claims 1
• 229920001525 carrageenan Polymers 0.000 claims 1
• 239000003795 chemical substances by application Substances 0.000 claims 1
• 208000027157 chronic rhinosinusitis Diseases 0.000 claims 1
• 239000003085 diluting agent Substances 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims 1
• 235000019414 erythritol Nutrition 0.000 claims 1
• 229940009714 erythritol Drugs 0.000 claims 1
• 239000008103 glucose Substances 0.000 claims 1
• 229960001031 glucose Drugs 0.000 claims 1
• 235000001727 glucose Nutrition 0.000 claims 1
• 239000000644 isotonic solution Substances 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 208000037916 non-allergic rhinitis Diseases 0.000 claims 1
• 239000000843 powder Substances 0.000 claims 1
• 210000002345 respiratory system Anatomy 0.000 claims 1
• 201000009890 sinusitis Diseases 0.000 claims 1
• 239000011780 sodium chloride Substances 0.000 claims 1
• 230000001225 therapeutic effect Effects 0.000 claims 1
• UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 1