JP2019503221A - バイオプリンター - Google Patents
バイオプリンター Download PDFInfo
- Publication number
- JP2019503221A JP2019503221A JP2018534171A JP2018534171A JP2019503221A JP 2019503221 A JP2019503221 A JP 2019503221A JP 2018534171 A JP2018534171 A JP 2018534171A JP 2018534171 A JP2018534171 A JP 2018534171A JP 2019503221 A JP2019503221 A JP 2019503221A
- Authority
- JP
- Japan
- Prior art keywords
- connector
- spray head
- bioprinter
- discharge pipe
- fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007921 spray Substances 0.000 claims abstract description 101
- 239000000463 material Substances 0.000 claims abstract description 95
- 238000007639 printing Methods 0.000 abstract description 75
- 230000001771 impaired effect Effects 0.000 abstract description 2
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 239000012530 fluid Substances 0.000 description 85
- 238000000034 method Methods 0.000 description 12
- 230000008569 process Effects 0.000 description 9
- 230000000694 effects Effects 0.000 description 6
- 239000000976 ink Substances 0.000 description 6
- 238000003780 insertion Methods 0.000 description 6
- 230000037431 insertion Effects 0.000 description 6
- 238000010146 3D printing Methods 0.000 description 4
- 239000012620 biological material Substances 0.000 description 4
- 238000005507 spraying Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 238000009413 insulation Methods 0.000 description 3
- 238000013461 design Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000000017 hydrogel Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 230000013011 mating Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 230000004308 accommodation Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
- B29C64/205—Means for applying layers
- B29C64/209—Heads; Nozzles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/17—Ink jet characterised by ink handling
- B41J2/175—Ink supply systems ; Circuit parts therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/17—Ink jet characterised by ink handling
- B41J2/175—Ink supply systems ; Circuit parts therefor
- B41J2/17503—Ink cartridges
- B41J2/17513—Inner structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/17—Ink jet characterised by ink handling
- B41J2/175—Ink supply systems ; Circuit parts therefor
- B41J2/17503—Ink cartridges
- B41J2/17553—Outer structure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/10—Processes of additive manufacturing
- B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
- B29C64/255—Enclosures for the building material, e.g. powder containers
- B29C64/259—Interchangeable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/30—Auxiliary operations or equipment
- B29C64/307—Handling of material to be used in additive manufacturing
- B29C64/321—Feeding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
Abstract
Description
既存のバイオプリンターは一般に、迅速挿入構造体を用いて、当該迅速挿入構造体の両端部がスプレーヘッド及びプリンティング材料容器にそれぞれ接近して差し込まれ且つ、ソケットされるように、スプレーヘッドとプリンティング材料容器とを接続する。そのような接続構造体は、安定性に乏しい。迅速挿入構造体はまた、通常、使用中に他のチューブと協同する必要があり、これはプリンティング材料の温度制御にとって好ましくなく、さらに、取付け及び取外し中に大きな操作スペースが必要である。
Claims (12)
- スプレーヘッド(1)、コネクタ(2)及び排出パイプ(3)を有するバイオプリンティング材料容器を含むバイオプリンターであって、ここで、コネクタ(2)の第1の端部が、排出パイプ(3)とねじ結合され、コネクタ(2)の第2の端部が、スプレーヘッド(1)と着脱可能で結合される、バイオプリンター。
- 前記排出パイプ(3)の出口端部が、第1の雄ねじを備え、前記コネクタ(2)の第1の端が、前記出口端部を収容するための第1の収容空洞を備え、ここで前記第1の収容空洞が、前記第1の雄ねじと篏合する第1の雌ねじが内部に設けられ、前記出口端部が、前記コネクタ(2)の第1の端部に挿入され、ねじ結合される、請求項1に記載のバイオプリンター。
- 前記第1の収容空洞が、前記コネクタ(2)の第2の端部に向かってテーパになったセクションを有する、請求項2に記載のバイオプリンター。
- 前記第1の収容空洞のセクションが、円錐形状である、請求項3に記載のバイオプリンター。
- 前記円錐形状の円錐度が、6%である、請求項4に記載のバイオプリンター。
- 前記スプレーヘッド(1)が、着脱可能且つ、回転不能で取付けられる取付けブロック(4)をさらに含む、請求項1に記載のバイオプリンター。
- 円周制限構造が、前記スプレーヘッド(1)と前記取付けブロック(4)の間に設けられ、前記スプレーヘッド(1)と前記取付けブロック(4)の相対回転を制限する、請求項6に記載のバイオプリンター。
- 着脱可能な円周制限部材が、前記コネクタ(2)と前記スプレーヘッド(1)の間に設けられ、前記コネクタ(2)と前記スプレーヘッド(1)の間の相対回転を制限する、請求項1に記載のバイオプリンター。
- 前記スプレーヘッド(1)が、着脱可能且つ、回転不能で取付けられた取付けブロック(4)をさらに含み、ここで、前記コネクタ(2)の第2の端部が、第2の雄ねじを備え、前記スプレーヘッド(1)が、前記コネクタ(2)の第2の端部を収容するための第2の収容空洞を備え、前記第2の収容空洞が、前記第2の雄ねじと篏合する第2の雌ねじを内部に備え、前記コネクタ(2)の第2の端部が、前記第2の収容空洞内に挿入され、ねじ結合される、請求項1に記載のバイオプリンター。
- 前記コネクタ(2)が、前記コネクタ(2)の第1の端部と第2の端部の間に設けられ、放射状に突出する軸制限部分(21)を含み、前記バイオプリンターが、前記スプレーヘッド(1)と前記軸制限部分の間に設けられた弾性ワッシャから構成される、請求項9に記載のバイオプリンター。
- 前記コネクタ(2)の第2の端部と前記スプレーヘッド(1)の間のねじ締結力が、前記コネクタ(2)の第1端部と前記排出パイプ(3)の間のねじ締結力よりも大きい、請求項9に記載のバイオプリンター。
- 前記バイオプリンターが、3Dバイオプリンターである、請求項1に記載のバイオプリンター。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2015/099827 WO2017113171A1 (zh) | 2015-12-30 | 2015-12-30 | 生物打印机 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2019503221A true JP2019503221A (ja) | 2019-02-07 |
JP6710767B2 JP6710767B2 (ja) | 2020-06-17 |
Family
ID=59224149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018534171A Expired - Fee Related JP6710767B2 (ja) | 2015-12-30 | 2015-12-30 | バイオプリンター |
Country Status (4)
Country | Link |
---|---|
US (1) | US10828830B2 (ja) |
EP (1) | EP3398778A4 (ja) |
JP (1) | JP6710767B2 (ja) |
WO (1) | WO2017113171A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4039475A1 (en) | 2021-02-03 | 2022-08-10 | AJL Ophthalmic, S.A. | 3d printer to generate curved biological tissue |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011125475A1 (ja) * | 2010-03-31 | 2011-10-13 | テルモ株式会社 | シリンジ |
CN104786495A (zh) * | 2015-03-25 | 2015-07-22 | 中山市迪迈打印科技有限公司 | 用于三维打印机的喷头 |
CN105167879A (zh) * | 2015-06-25 | 2015-12-23 | 南京律动生物科技有限公司 | 一种双流道喷嘴 |
WO2015196085A2 (en) * | 2014-06-20 | 2015-12-23 | Clearside Biomedical, Inc. | Variable diameter cannula and methods for controlling insertion depth for medicament delivery |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09109203A (ja) | 1995-10-13 | 1997-04-28 | Ube Ind Ltd | 射出成形機のシャットオフノズル |
US7939003B2 (en) | 2004-08-11 | 2011-05-10 | Cornell Research Foundation, Inc. | Modular fabrication systems and methods |
US20100029504A1 (en) * | 2007-01-16 | 2010-02-04 | Phigenix, Inc. | Detecting pax2 for the diagnosis of breast cancer |
US7399175B2 (en) | 2006-02-13 | 2008-07-15 | Brown Machine, Llc | Thermoformer plug assist drive assembly |
JP5952081B2 (ja) | 2012-05-16 | 2016-07-13 | 東洋機械金属株式会社 | 射出成形機 |
CA2943965C (en) * | 2014-03-25 | 2021-08-24 | Biobots, Inc. | Methods, devices, and systems for the fabrication of materials and tissues utilizing electromagnetic radiation |
CN203994731U (zh) | 2014-08-19 | 2014-12-10 | 深圳森工科技有限公司 | 3d打印机的打印头喷头组件 |
CN204076844U (zh) | 2014-08-25 | 2015-01-07 | 江苏威宝仕科技有限公司 | 一种用于3d打印机的防漏防堵塞喷头组件 |
CN104369380B (zh) | 2014-11-06 | 2016-09-14 | 北京建解建筑设计咨询有限公司 | 一种打印头及设有该打印头的打印机 |
CN107000318B (zh) * | 2014-12-01 | 2018-08-21 | 沙特基础工业全球技术有限公司 | 用于材料挤出增材制造的喷嘴工具改变 |
CN204640815U (zh) | 2015-05-20 | 2015-09-16 | 深圳市同创三维科技有限公司 | 一种3d打印机喷头结构 |
CN205291606U (zh) * | 2015-12-22 | 2016-06-08 | 珠海天威飞马打印耗材有限公司 | 打印头及三维打印机 |
CN205443253U (zh) | 2015-12-30 | 2016-08-10 | 四川蓝光英诺生物科技股份有限公司 | 生物打印机 |
CN105647802B (zh) | 2015-12-30 | 2018-11-23 | 四川蓝光英诺生物科技股份有限公司 | 生物打印机 |
-
2015
- 2015-12-30 JP JP2018534171A patent/JP6710767B2/ja not_active Expired - Fee Related
- 2015-12-30 US US16/067,479 patent/US10828830B2/en active Active
- 2015-12-30 WO PCT/CN2015/099827 patent/WO2017113171A1/zh active Application Filing
- 2015-12-30 EP EP15911800.9A patent/EP3398778A4/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011125475A1 (ja) * | 2010-03-31 | 2011-10-13 | テルモ株式会社 | シリンジ |
WO2015196085A2 (en) * | 2014-06-20 | 2015-12-23 | Clearside Biomedical, Inc. | Variable diameter cannula and methods for controlling insertion depth for medicament delivery |
CN104786495A (zh) * | 2015-03-25 | 2015-07-22 | 中山市迪迈打印科技有限公司 | 用于三维打印机的喷头 |
CN105167879A (zh) * | 2015-06-25 | 2015-12-23 | 南京律动生物科技有限公司 | 一种双流道喷嘴 |
Also Published As
Publication number | Publication date |
---|---|
EP3398778A4 (en) | 2019-08-21 |
US20190001568A1 (en) | 2019-01-03 |
EP3398778A1 (en) | 2018-11-07 |
WO2017113171A1 (zh) | 2017-07-06 |
US10828830B2 (en) | 2020-11-10 |
JP6710767B2 (ja) | 2020-06-17 |
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