JP2019503171A5 - - Google Patents

Download PDF

Info

Publication number
JP2019503171A5
JP2019503171A5 JP2018532655A JP2018532655A JP2019503171A5 JP 2019503171 A5 JP2019503171 A5 JP 2019503171A5 JP 2018532655 A JP2018532655 A JP 2018532655A JP 2018532655 A JP2018532655 A JP 2018532655A JP 2019503171 A5 JP2019503171 A5 JP 2019503171A5
Authority
JP
Japan
Prior art keywords
amino acid
nagal
human
polypeptide
replaced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018532655A
Other languages
English (en)
Japanese (ja)
Other versions
JP6956417B2 (ja
JP2019503171A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2016/082304 external-priority patent/WO2017109034A1/en
Publication of JP2019503171A publication Critical patent/JP2019503171A/ja
Publication of JP2019503171A5 publication Critical patent/JP2019503171A5/ja
Application granted granted Critical
Publication of JP6956417B2 publication Critical patent/JP6956417B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018532655A 2015-12-24 2016-12-22 ヒトα−N−アセチルガラクトサミニダーゼポリペプチド Expired - Fee Related JP6956417B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15202729 2015-12-24
EP15202729.8 2015-12-24
PCT/EP2016/082304 WO2017109034A1 (en) 2015-12-24 2016-12-22 Human alpha-n-acetylgalactosaminidase polypeptide

Publications (3)

Publication Number Publication Date
JP2019503171A JP2019503171A (ja) 2019-02-07
JP2019503171A5 true JP2019503171A5 (cg-RX-API-DMAC10.html) 2020-02-06
JP6956417B2 JP6956417B2 (ja) 2021-11-02

Family

ID=55129455

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018532655A Expired - Fee Related JP6956417B2 (ja) 2015-12-24 2016-12-22 ヒトα−N−アセチルガラクトサミニダーゼポリペプチド

Country Status (6)

Country Link
US (1) US11040114B2 (cg-RX-API-DMAC10.html)
EP (1) EP3393501B1 (cg-RX-API-DMAC10.html)
JP (1) JP6956417B2 (cg-RX-API-DMAC10.html)
KR (1) KR20180088919A (cg-RX-API-DMAC10.html)
CA (1) CA3008975A1 (cg-RX-API-DMAC10.html)
WO (1) WO2017109034A1 (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180088919A (ko) * 2015-12-24 2018-08-07 옥시레인 유케이 리미티드 인간 알파-n-아세틸갈락토사미니다아제 폴리펩티드
WO2019051297A1 (en) * 2017-09-08 2019-03-14 The Nemours Foundation AGENT, DEVICE AND BLOOD CIRCULATION SYSTEM FOR TREATING LYSOSOMAL DISEASES, AND METHODS OF TREATING LYSOSOMAL DISEASES
EP3773702A2 (en) 2018-04-05 2021-02-17 CureVac AG Novel yellow fever nucleic acid molecules for vaccination
WO2021222232A1 (en) * 2020-04-28 2021-11-04 The Trustees Of The University Of Pennsylvania Compositions and uses thereof for treatment of angelman syndrome

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
US4929555A (en) 1987-10-19 1990-05-29 Phillips Petroleum Company Pichia transformation
US20020123476A1 (en) 1991-03-19 2002-09-05 Emanuele R. Martin Therapeutic delivery compositions and methods of use thereof
US5587308A (en) 1992-06-02 1996-12-24 The United States Of America As Represented By The Department Of Health & Human Services Modified adeno-associated virus vector capable of expression from a novel promoter
US6806084B1 (en) 1992-06-04 2004-10-19 The Regents Of The University Of California Methods for compositions for in vivo gene delivery
US5478745A (en) 1992-12-04 1995-12-26 University Of Pittsburgh Recombinant viral vector system
EP0922109A1 (en) 1996-05-21 1999-06-16 Novo Nordisk A/S Novel yeast promoters suitable for expression cloning in yeast and heterologous expression of proteins in yeast
US20060014264A1 (en) 2004-07-13 2006-01-19 Stowers Institute For Medical Research Cre/lox system with lox sites having an extended spacer region
WO2006129080A1 (en) 2005-05-31 2006-12-07 The Institute Of Cancer Research: Royal Cancer Hospital Materials and methods for transducing cells with a viral vector
JP4368925B2 (ja) * 2005-11-18 2009-11-18 財団法人 東京都医学研究機構 基質特異性を変換した新規高機能酵素
JP5967861B2 (ja) 2007-04-03 2016-08-10 オキシレイン ユーケー リミテッド 分子のグリコシル化
US8569032B2 (en) * 2007-05-18 2013-10-29 Tokyo Metropolitan Institute Of Medical Science Proteins having acquired A-galactosidase activity
KR102000383B1 (ko) * 2009-09-29 2019-07-15 유니버시테이트 젠트 만노스-1-포스포-6-만노스 결합의 포스포-6-만노스로의 가수분해
BR112013007616B1 (pt) 2010-09-29 2023-01-24 Oxyrane Uk Limited Métodos para retirar o cap ("uncapping") de porções de manose-1- fosfo-6-manose e desmanosilar n-glicanos fosforilados em uma glicoproteína, para direcionar uma glicoproteína para o interior de uma célula de mamífero, e para converter uma glicoproteína de uma primeira forma que não se liga substancialmente a um receptor de manose-6-fosfato em uma segunda forma que se liga substancialmente a um receptor de manose-6-fosfato em uma célula de mamífero
CA2867237C (en) 2012-03-15 2024-01-02 Wouter Vervecken Methods and materials for treatment of pompe's disease
CA2970638A1 (en) * 2014-12-22 2016-06-30 Codexis, Inc. Human alpha-galactosidase variants
KR20180088919A (ko) * 2015-12-24 2018-08-07 옥시레인 유케이 리미티드 인간 알파-n-아세틸갈락토사미니다아제 폴리펩티드

Similar Documents

Publication Publication Date Title
JP6396415B2 (ja) コレステロールレベルを変更する組成物および方法
US20250154490A1 (en) Mutant cytidine deaminases with improved editing precision
RU2010122053A (ru) Иммуносупрессорные полипептиды и нуклеиновые кислоты
JP2019033757A (ja) 核タンパク質の産生のための修飾ポリヌクレオチド
PE20190352A1 (es) Proteinas de fusion gdf 15 y usos de estas
NZ602351A (en) Axmi-115, axmi-113, axmi-005, axmi-163 and axmi-184 : vip3a insecticidal proteins from bacillus thuringiensis and methods for their use
CN113811317B (zh) 突变vsv胞外域多肽及其用途
SA522433360B1 (ar) L-أَسْباراجيناز مُعدل
JP2018510623A (ja) Nkg2d及び腫瘍関連抗原に対する二価抗体
WO2011036443A3 (en) Si protease c- terminal polypeptides and uses thereof for treating inflammation or coagulation disorders
IL288541B (en) Vaccine against rsv
JP2013542913A5 (cg-RX-API-DMAC10.html)
FI3256579T3 (fi) Kysteiiniproteaasi
US20230075095A1 (en) Polypeptides and their use
UA110599C2 (uk) Пептид для імунотерапії пухлин, включаючи нейрональні пухлини та пухлини мозку
WO2009100934A9 (en) Identification of a novel cysteine-rich cell penetrating peptide
IN2012DN02981A (cg-RX-API-DMAC10.html)
JP2014506450A5 (cg-RX-API-DMAC10.html)
EP4083058A2 (en) Delivery constructs for transcytosis and related methods
MX376466B (es) Vectores de expresion para una secrecion de proteina mejorada.
FI4034555T3 (fi) Dap10/dap12-fuusiopolypeptidit
EP4021479A2 (en) Modified tff2 polypeptides
WO2024121790A3 (en) Cas12 protein, crispr-cas system and uses thereof
ZA202304029B (en) Cxcl9 and variants thereof for immunotherapy of cancer diseases
WO2010007144A3 (en) Mutated netrin-4 proteins, fragments thereof and their uses as drugs