JP2019500850A5 - - Google Patents

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Publication number
JP2019500850A5
JP2019500850A5 JP2018521279A JP2018521279A JP2019500850A5 JP 2019500850 A5 JP2019500850 A5 JP 2019500850A5 JP 2018521279 A JP2018521279 A JP 2018521279A JP 2018521279 A JP2018521279 A JP 2018521279A JP 2019500850 A5 JP2019500850 A5 JP 2019500850A5
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JP
Japan
Prior art keywords
seq
receptor agonist
cd137l
agonist protein
domain
Prior art date
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Application number
JP2018521279A
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English (en)
Japanese (ja)
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JP7033062B2 (ja
JP2019500850A (ja
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Publication date
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Priority claimed from PCT/EP2016/075543 external-priority patent/WO2017068183A1/en
Publication of JP2019500850A publication Critical patent/JP2019500850A/ja
Publication of JP2019500850A5 publication Critical patent/JP2019500850A5/ja
Application granted granted Critical
Publication of JP7033062B2 publication Critical patent/JP7033062B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018521279A 2015-10-23 2016-10-24 一本鎖ｃｄ１３７受容体アゴニストタンパク質 Expired - Fee Related JP7033062B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562245838P 2015-10-23 2015-10-23
US62/245,838 2015-10-23
PCT/EP2016/075543 WO2017068183A1 (en) 2015-10-23 2016-10-24 Single-chain cd137-receptor agonist proteins

Publications (3)

Publication Number Publication Date
JP2019500850A JP2019500850A (ja) 2019-01-17
JP2019500850A5 true JP2019500850A5 (cg-RX-API-DMAC7.html) 2019-12-05
JP7033062B2 JP7033062B2 (ja) 2022-03-09

Family

ID=57208274

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018521279A Expired - Fee Related JP7033062B2 (ja) 2015-10-23 2016-10-24 一本鎖ｃｄ１３７受容体アゴニストタンパク質

Country Status (7)

Country Link
US (2) US10870688B2 (cg-RX-API-DMAC7.html)
EP (1) EP3365448A1 (cg-RX-API-DMAC7.html)
JP (1) JP7033062B2 (cg-RX-API-DMAC7.html)
CN (1) CN108368511B (cg-RX-API-DMAC7.html)
AU (2) AU2016341400B2 (cg-RX-API-DMAC7.html)
CA (1) CA3002588C (cg-RX-API-DMAC7.html)
WO (1) WO2017068183A1 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10202102897PA (en) 2017-01-20 2021-04-29 Magenta Therapeutics Inc Compositions and methods for the depletion of cd137+ cells
WO2019109238A1 (en) 2017-12-05 2019-06-13 Lyvgen Biopharma Co., Ltd. Anti-cd137 antibodies and uses thereof
WO2020069382A1 (en) * 2018-09-28 2020-04-02 Lyvgen Biopharma Co., Ltd. Anti-cd137 binding molecules having engineered fc domains and therapeutic uses thereof
KR20220008306A (ko) 2019-05-10 2022-01-20 리브젠 바이오파마 코., 엘티디. 인간화 항-cd137 항체 및 이의 용도
US20230212260A1 (en) 2020-05-15 2023-07-06 Apogenix Ag Multi-specific immune modulators
KR102251580B1 (ko) * 2020-08-14 2021-05-13 최상호 이중 보온관 접속용 레듀사 및 이를 이용한 시공방법
WO2023088889A1 (en) 2021-11-16 2023-05-25 Apogenix Ag CD137 ligands
WO2023088876A1 (en) 2021-11-16 2023-05-25 Apogenix Ag Multi-specific immune modulators
CN120202214A (zh) * 2022-10-28 2025-06-24 Fbd生物制品有限公司 经工程改造的4-1bbl变体及其使用方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ302303B6 (cs) * 1998-08-25 2011-02-16 Merck Patent Gmbh Homodimerní fúzní protein vykazující inhibicní aktivitu na angiogenezi, zpusob jeho produkce, molekula DNA a replikovatelný expresní vektor
US20030223989A1 (en) * 2002-04-18 2003-12-04 Pluenneke John D. CD137 agonists to treat patients with IgE-mediated conditions
JP2008537941A (ja) * 2005-03-31 2008-10-02 ゼンコー・インコーポレイテッド 最適化特性を有するＦｃ変異体
DK2604693T3 (en) * 2008-07-21 2016-05-30 Apogenix Gmbh Single-chain TNFSF molecules
MY162489A (en) * 2010-12-23 2017-06-15 Janssen Biotech Inc ACTIVE PROTEASE-RESISTANT ANTIBODY Fc MUTANTS
US9822179B2 (en) * 2011-04-01 2017-11-21 Universitat Stuttgart Recombinant TNF ligand family member polypeptides with antibody binding domain and uses therefor
CA2858806A1 (en) * 2011-12-23 2013-06-27 Innate Pharma Enzymatic conjugation of polypeptides
CA3002587A1 (en) * 2015-10-23 2017-04-27 Apogenix Ag Single-chain light receptor agonist proteins
CA3002602C (en) * 2015-10-23 2021-11-02 Apogenix Ag Single-chain cd27-receptor agonist proteins

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