JP2019112416A5 - - Google Patents
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- Publication number
- JP2019112416A5 JP2019112416A5 JP2019026073A JP2019026073A JP2019112416A5 JP 2019112416 A5 JP2019112416 A5 JP 2019112416A5 JP 2019026073 A JP2019026073 A JP 2019026073A JP 2019026073 A JP2019026073 A JP 2019026073A JP 2019112416 A5 JP2019112416 A5 JP 2019112416A5
- Authority
- JP
- Japan
- Prior art keywords
- entinostat
- administration
- exemestane
- combination
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- INVTYAOGFAGBOE-UHFFFAOYSA-N entinostat Chemical compound NC1=CC=CC=C1NC(=O)C(C=C1)=CC=C1CNC(=O)OCC1=CC=CN=C1 INVTYAOGFAGBOE-UHFFFAOYSA-N 0.000 claims 32
- 229950005837 entinostat Drugs 0.000 claims 32
- BFYIZQONLCFLEV-DAELLWKTSA-N Aromasine Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=C)C2=C1 BFYIZQONLCFLEV-DAELLWKTSA-N 0.000 claims 13
- 229960000255 exemestane Drugs 0.000 claims 13
- 235000020937 fasting conditions Nutrition 0.000 claims 6
- 235000013305 food Nutrition 0.000 claims 4
- 235000012054 meals Nutrition 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361819505P | 2013-05-03 | 2013-05-03 | |
| US61/819,505 | 2013-05-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016512076A Division JP2016522188A (ja) | 2013-05-03 | 2014-05-02 | 癌の処置方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019112416A JP2019112416A (ja) | 2019-07-11 |
| JP2019112416A5 true JP2019112416A5 (enExample) | 2019-09-19 |
| JP6860949B2 JP6860949B2 (ja) | 2021-04-21 |
Family
ID=51843995
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016512076A Pending JP2016522188A (ja) | 2013-05-03 | 2014-05-02 | 癌の処置方法 |
| JP2019026073A Active JP6860949B2 (ja) | 2013-05-03 | 2019-02-15 | 癌の処置方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016512076A Pending JP2016522188A (ja) | 2013-05-03 | 2014-05-02 | 癌の処置方法 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2991650A4 (enExample) |
| JP (2) | JP2016522188A (enExample) |
| KR (1) | KR102337598B1 (enExample) |
| CN (1) | CN105492007A (enExample) |
| HK (1) | HK1223547A1 (enExample) |
| WO (1) | WO2014179738A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180353602A1 (en) * | 2015-06-29 | 2018-12-13 | Syndax Pharmaceuticals, Inc. | Combination of hdac inhibitor and anti-pd-l1 antibody for treatment of cancer |
| US20190282541A1 (en) * | 2016-07-20 | 2019-09-19 | Eisai R&D Management Co., Ltd. | Use of eribulin and histone deacetylase inhibitors in the treatment of cancer |
| KR20240042244A (ko) | 2017-05-19 | 2024-04-01 | 신닥스 파마슈티컬스, 인크. | 조합 요법 |
| BR112020024762A2 (pt) | 2018-06-06 | 2021-03-23 | Arena Pharmaceuticals, Inc. | métodos de tratamento de condições relacionadas ao receptor s1p1 |
| RU2680603C1 (ru) * | 2018-11-08 | 2019-02-25 | Ильясов Шамиль Сионович | Применение 3-о-сульфамата-16,16-диметил-d-гомоэквиленина для лечения онкологических заболеваний |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006099396A2 (en) * | 2005-03-11 | 2006-09-21 | The Regents Of The University Of Colorado | Histone deacetylase inhibitors sensitize cancer cells to epidermal growth factor inhibitors |
| WO2008008434A1 (en) * | 2006-07-11 | 2008-01-17 | Mutual Pharmaceutical Company, Inc. | Controlled-release formulations |
| US20100305167A1 (en) * | 2007-11-19 | 2010-12-02 | Syndax Pharmaceuticals, Inc. | Administration of an Inhibitor of HDAC |
| US20110002989A1 (en) * | 2008-03-07 | 2011-01-06 | Pfizer Inc. | Methods, dosage forms and kits for administering ziprasidone without food |
| US20110182888A1 (en) * | 2008-04-08 | 2011-07-28 | Peter Ordentlich | Administration of an Inhibitor of HDAC, an Inhibitor of HER-2, and a Selective Estrogen Receptor Modulator |
| CN107982270A (zh) * | 2011-09-02 | 2018-05-04 | 辛达克斯制药股份有限公司 | 治疗乳腺癌的方法 |
-
2014
- 2014-05-02 KR KR1020157033947A patent/KR102337598B1/ko active Active
- 2014-05-02 JP JP2016512076A patent/JP2016522188A/ja active Pending
- 2014-05-02 CN CN201480038420.7A patent/CN105492007A/zh active Pending
- 2014-05-02 EP EP14791444.4A patent/EP2991650A4/en not_active Withdrawn
- 2014-05-02 HK HK16111783.0A patent/HK1223547A1/zh unknown
- 2014-05-02 WO PCT/US2014/036651 patent/WO2014179738A1/en not_active Ceased
-
2019
- 2019-02-15 JP JP2019026073A patent/JP6860949B2/ja active Active
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