JP2019068814A5 - - Google Patents
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- Publication number
- JP2019068814A5 JP2019068814A5 JP2018224316A JP2018224316A JP2019068814A5 JP 2019068814 A5 JP2019068814 A5 JP 2019068814A5 JP 2018224316 A JP2018224316 A JP 2018224316A JP 2018224316 A JP2018224316 A JP 2018224316A JP 2019068814 A5 JP2019068814 A5 JP 2019068814A5
- Authority
- JP
- Japan
- Prior art keywords
- ncbi gene
- gene
- ncbi
- configuration
- placental stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 description 195
- 210000004991 placental stem cell Anatomy 0.000 description 32
- 230000025164 anoikis Effects 0.000 description 28
- 210000004027 cell Anatomy 0.000 description 10
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 8
- 230000001105 regulatory effect Effects 0.000 description 8
- 102100028028 Double-stranded RNA-binding protein Staufen homolog 2 Human genes 0.000 description 6
- 102100027867 FH2 domain-containing protein 1 Human genes 0.000 description 6
- 102000058062 Glucose Transporter Type 3 Human genes 0.000 description 6
- 101000697573 Homo sapiens Double-stranded RNA-binding protein Staufen homolog 2 Proteins 0.000 description 6
- 101001060553 Homo sapiens FH2 domain-containing protein 1 Proteins 0.000 description 6
- 101001091564 Homo sapiens Kinase non-catalytic C-lobe domain-containing protein 1 Proteins 0.000 description 6
- 101001038043 Homo sapiens Lysophosphatidic acid receptor 4 Proteins 0.000 description 6
- 101001018196 Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Proteins 0.000 description 6
- 102100035795 Kinase non-catalytic C-lobe domain-containing protein 1 Human genes 0.000 description 6
- 102100040405 Lysophosphatidic acid receptor 4 Human genes 0.000 description 6
- 102100033127 Mitogen-activated protein kinase kinase kinase 5 Human genes 0.000 description 6
- 108091006298 SLC2A3 Proteins 0.000 description 6
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 description 4
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 description 4
- 102000003729 Neprilysin Human genes 0.000 description 4
- 108090000028 Neprilysin Proteins 0.000 description 4
- 239000004055 small Interfering RNA Substances 0.000 description 4
- 102100027087 28S ribosomal protein S18c, mitochondrial Human genes 0.000 description 3
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 description 3
- 102100032044 Amphoterin-induced protein 1 Human genes 0.000 description 3
- 102100024641 BRCA1-A complex subunit Abraxas 1 Human genes 0.000 description 3
- 102100035750 Biorientation of chromosomes in cell division protein 1-like 2 Human genes 0.000 description 3
- ZEOWTGPWHLSLOG-UHFFFAOYSA-N Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(c1)C1CC1)C(=O)Nc1cccc(c1)C(F)(F)F Chemical compound Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(c1)C1CC1)C(=O)Nc1cccc(c1)C(F)(F)F ZEOWTGPWHLSLOG-UHFFFAOYSA-N 0.000 description 3
- 102100029397 Chloride channel CLIC-like protein 1 Human genes 0.000 description 3
- 108010005939 Ciliary Neurotrophic Factor Proteins 0.000 description 3
- 102100031614 Ciliary neurotrophic factor Human genes 0.000 description 3
- 102100039259 Cytochrome c oxidase subunit 8A, mitochondrial Human genes 0.000 description 3
- 102100027416 E3 ubiquitin-protein ligase RNF103 Human genes 0.000 description 3
- 102100039658 E3 ubiquitin-protein ligase pellino homolog 2 Human genes 0.000 description 3
- 102100035438 FRAS1-related extracellular matrix protein 3 Human genes 0.000 description 3
- 102100023593 Fibroblast growth factor receptor 1 Human genes 0.000 description 3
- 101710182386 Fibroblast growth factor receptor 1 Proteins 0.000 description 3
- 102100030334 Friend leukemia integration 1 transcription factor Human genes 0.000 description 3
- 102100030892 Fructose-1,6-bisphosphatase isozyme 2 Human genes 0.000 description 3
- 102100033713 Gamma-secretase subunit APH-1B Human genes 0.000 description 3
- 101000694321 Homo sapiens 28S ribosomal protein S18c, mitochondrial Proteins 0.000 description 3
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 description 3
- 101000776170 Homo sapiens Amphoterin-induced protein 1 Proteins 0.000 description 3
- 101000760704 Homo sapiens BRCA1-A complex subunit Abraxas 1 Proteins 0.000 description 3
- 101000874054 Homo sapiens Biorientation of chromosomes in cell division protein 1-like 2 Proteins 0.000 description 3
- 101000989992 Homo sapiens Chloride channel CLIC-like protein 1 Proteins 0.000 description 3
- 101000745956 Homo sapiens Cytochrome c oxidase subunit 8A, mitochondrial Proteins 0.000 description 3
- 101000650319 Homo sapiens E3 ubiquitin-protein ligase RNF103 Proteins 0.000 description 3
- 101000606718 Homo sapiens E3 ubiquitin-protein ligase pellino homolog 2 Proteins 0.000 description 3
- 101000877877 Homo sapiens FRAS1-related extracellular matrix protein 3 Proteins 0.000 description 3
- 101000930766 Homo sapiens Far upstream element-binding protein 2 Proteins 0.000 description 3
- 101001062996 Homo sapiens Friend leukemia integration 1 transcription factor Proteins 0.000 description 3
- 101001063910 Homo sapiens Fructose-1,6-bisphosphatase isozyme 2 Proteins 0.000 description 3
- 101000733778 Homo sapiens Gamma-secretase subunit APH-1B Proteins 0.000 description 3
- 101001082063 Homo sapiens Interferon-induced protein with tetratricopeptide repeats 5 Proteins 0.000 description 3
- 101001076407 Homo sapiens Interleukin-1 receptor antagonist protein Proteins 0.000 description 3
- 101000605741 Homo sapiens Kinesin-like protein KIF24 Proteins 0.000 description 3
- 101000984653 Homo sapiens Large subunit GTPase 1 homolog Proteins 0.000 description 3
- 101001093748 Homo sapiens Phosphatidylinositol N-acetylglucosaminyltransferase subunit P Proteins 0.000 description 3
- 101000728125 Homo sapiens Plasma membrane calcium-transporting ATPase 2 Proteins 0.000 description 3
- 101000728117 Homo sapiens Plasma membrane calcium-transporting ATPase 4 Proteins 0.000 description 3
- 101000874165 Homo sapiens Probable ATP-dependent RNA helicase DDX41 Proteins 0.000 description 3
- 101000901938 Homo sapiens Probable ATP-dependent RNA helicase DHX34 Proteins 0.000 description 3
- 101000893493 Homo sapiens Protein flightless-1 homolog Proteins 0.000 description 3
- 101000594435 Homo sapiens Protein-lysine methyltransferase METTL21C Proteins 0.000 description 3
- 101000884234 Homo sapiens Renal cancer differentiation gene 1 protein Proteins 0.000 description 3
- 101001091999 Homo sapiens Rho GTPase-activating protein 20 Proteins 0.000 description 3
- 101000637795 Homo sapiens SH3 domain and tetratricopeptide repeat-containing protein 2 Proteins 0.000 description 3
- 101000824928 Homo sapiens Sorting nexin-31 Proteins 0.000 description 3
- 101000801891 Homo sapiens Thioredoxin, mitochondrial Proteins 0.000 description 3
- 101000834937 Homo sapiens Tomoregulin-1 Proteins 0.000 description 3
- 101000680173 Homo sapiens Transmembrane protein 217 Proteins 0.000 description 3
- 101000648679 Homo sapiens Transmembrane protein 79 Proteins 0.000 description 3
- 101000777644 Homo sapiens Uncharacterized protein C4orf17 Proteins 0.000 description 3
- 101000671620 Homo sapiens Usher syndrome type-1C protein-binding protein 1 Proteins 0.000 description 3
- 101000649175 Homo sapiens XK-related protein 7 Proteins 0.000 description 3
- 101000734338 Homo sapiens [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial Proteins 0.000 description 3
- 102100027356 Interferon-induced protein with tetratricopeptide repeats 5 Human genes 0.000 description 3
- 102100026018 Interleukin-1 receptor antagonist protein Human genes 0.000 description 3
- 102100038403 Kinesin-like protein KIF24 Human genes 0.000 description 3
- 102100027113 Large subunit GTPase 1 homolog Human genes 0.000 description 3
- 102100035188 Phosphatidylinositol N-acetylglucosaminyltransferase subunit P Human genes 0.000 description 3
- 102100029743 Plasma membrane calcium-transporting ATPase 4 Human genes 0.000 description 3
- 102100035727 Probable ATP-dependent RNA helicase DDX41 Human genes 0.000 description 3
- 102100022411 Probable ATP-dependent RNA helicase DHX34 Human genes 0.000 description 3
- 102100035509 Protein-lysine methyltransferase METTL21C Human genes 0.000 description 3
- 102100038066 Renal cancer differentiation gene 1 protein Human genes 0.000 description 3
- 102100035751 Rho GTPase-activating protein 20 Human genes 0.000 description 3
- 102100032022 SH3 domain and tetratricopeptide repeat-containing protein 2 Human genes 0.000 description 3
- 102100022384 Sorting nexin-31 Human genes 0.000 description 3
- 102100034795 Thioredoxin, mitochondrial Human genes 0.000 description 3
- 102100026159 Tomoregulin-1 Human genes 0.000 description 3
- 102100022215 Transmembrane protein 217 Human genes 0.000 description 3
- 102100028839 Transmembrane protein 79 Human genes 0.000 description 3
- 102100031591 Uncharacterized protein C4orf17 Human genes 0.000 description 3
- 102100040093 Usher syndrome type-1C protein-binding protein 1 Human genes 0.000 description 3
- 102100027922 XK-related protein 7 Human genes 0.000 description 3
- 102100034824 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial Human genes 0.000 description 3
- 108091027967 Small hairpin RNA Proteins 0.000 description 2
- 108020004459 Small interfering RNA Proteins 0.000 description 2
- 230000003278 mimic effect Effects 0.000 description 2
- 108020005544 Antisense RNA Proteins 0.000 description 1
- 229940122938 MicroRNA inhibitor Drugs 0.000 description 1
- 108700011259 MicroRNAs Proteins 0.000 description 1
- 239000003184 complementary RNA Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 239000002679 microRNA Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261737498P | 2012-12-14 | 2012-12-14 | |
| US61/737,498 | 2012-12-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547970A Division JP2016502844A (ja) | 2012-12-14 | 2013-12-13 | アノイキス抵抗性胎盤幹細胞及びその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020185486A Division JP2021045133A (ja) | 2012-12-14 | 2020-11-06 | アノイキス抵抗性胎盤幹細胞及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019068814A JP2019068814A (ja) | 2019-05-09 |
| JP2019068814A5 true JP2019068814A5 (enExample) | 2019-10-24 |
Family
ID=50934980
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547970A Pending JP2016502844A (ja) | 2012-12-14 | 2013-12-13 | アノイキス抵抗性胎盤幹細胞及びその使用 |
| JP2018224316A Pending JP2019068814A (ja) | 2012-12-14 | 2018-11-30 | アノイキス抵抗性胎盤幹細胞及びその使用 |
| JP2020185486A Withdrawn JP2021045133A (ja) | 2012-12-14 | 2020-11-06 | アノイキス抵抗性胎盤幹細胞及びその使用 |
| JP2022112849A Pending JP2022160451A (ja) | 2012-12-14 | 2022-07-14 | アノイキス抵抗性胎盤幹細胞及びその使用 |
| JP2024105938A Pending JP2024153631A (ja) | 2012-12-14 | 2024-07-01 | アノイキス抵抗性胎盤幹細胞及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547970A Pending JP2016502844A (ja) | 2012-12-14 | 2013-12-13 | アノイキス抵抗性胎盤幹細胞及びその使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020185486A Withdrawn JP2021045133A (ja) | 2012-12-14 | 2020-11-06 | アノイキス抵抗性胎盤幹細胞及びその使用 |
| JP2022112849A Pending JP2022160451A (ja) | 2012-12-14 | 2022-07-14 | アノイキス抵抗性胎盤幹細胞及びその使用 |
| JP2024105938A Pending JP2024153631A (ja) | 2012-12-14 | 2024-07-01 | アノイキス抵抗性胎盤幹細胞及びその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20150307879A1 (enExample) |
| EP (2) | EP2938196B1 (enExample) |
| JP (5) | JP2016502844A (enExample) |
| CN (2) | CN113481164A (enExample) |
| AU (1) | AU2013359076A1 (enExample) |
| CA (1) | CA2895106C (enExample) |
| WO (1) | WO2014093753A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2970883T3 (da) * | 2013-03-14 | 2021-08-09 | Celularity Inc | Forbedrede placenta stamceller og bruge deraf |
| CN107475419A (zh) * | 2017-09-22 | 2017-12-15 | 浙江大学 | Kndc1基因及其表达产物在卵巢癌检测中的应用 |
| CN110129321B (zh) * | 2019-07-08 | 2021-10-15 | 江苏医药职业学院 | 降低LSG1基因表达的siRNA、重组载体及其应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4798824A (en) | 1985-10-03 | 1989-01-17 | Wisconsin Alumni Research Foundation | Perfusate for the preservation of organs |
| US5190556A (en) | 1991-03-19 | 1993-03-02 | O.B. Tech, Inc. | Cord cutter sampler |
| US5552267A (en) | 1992-04-03 | 1996-09-03 | The Trustees Of Columbia University In The City Of New York | Solution for prolonged organ preservation |
| US5372581A (en) | 1993-07-21 | 1994-12-13 | Minneapolis Children's Services Corporation | Method and apparatus for placental blood collection |
| JP2002542349A (ja) | 1999-04-16 | 2002-12-10 | ダブリューエム・マーシュ・ライス・ユニバーシティー | ポリ（プロピレンフマラート）−ジアクリレートマクロマーで交差結合された生体分解性のポリ（プロピレンフマラート）ネットワーク |
| US6355699B1 (en) | 1999-06-30 | 2002-03-12 | Ethicon, Inc. | Process for manufacturing biomedical foams |
| EP2206772A3 (en) | 2000-12-06 | 2010-08-04 | Robert J. Hariri | Method of collecting placental stem cells |
| US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
| CA2437957C (en) | 2001-02-14 | 2014-04-22 | Robert J. Hariri | Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells |
| EP2336299A1 (en) | 2001-02-14 | 2011-06-22 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| US20030187515A1 (en) | 2002-03-26 | 2003-10-02 | Hariri Robert J. | Collagen biofabric and methods of preparing and using the collagen biofabric |
| CA2624925C (en) | 2005-10-13 | 2014-09-30 | Anthrogenesis Corporation | Immunomodulation using placental stem cells |
| AU2006332680A1 (en) | 2005-12-29 | 2007-07-12 | Anthrogenesis Corporation | Improved composition for collecting and preserving placental stem cells and methods of using the composition |
| ES2708933T3 (es) * | 2005-12-29 | 2019-04-12 | Celularity Inc | Poblaciones de células madre placentarias |
| WO2009044899A1 (ja) * | 2007-10-03 | 2009-04-09 | Kyowa Hakko Kirin Co., Ltd. | 細胞の増殖を制御する核酸 |
| CN101862315A (zh) * | 2009-04-17 | 2010-10-20 | 中国医学科学院血液病医院（血液学研究所） | 双取代苯基双胍诱导恶性肿瘤细胞失巢凋亡的用途 |
| WO2011056505A1 (en) * | 2009-10-26 | 2011-05-12 | Abbott Laboratories | Detection of chromosomal abnormalities associated with prognosis of non small cell lung cancer |
| DK2494039T3 (da) * | 2009-10-31 | 2019-08-19 | Genesis Tech Limited | Fremgangsmåder til reprogrammering af celler og anvendelser deraf |
| IL250234B2 (en) | 2010-04-07 | 2023-10-01 | Anthrogenesis Llc | Angiogenesis using placental stem cells |
| WO2012092458A2 (en) * | 2010-12-30 | 2012-07-05 | Anthrogenesis Corporation | Compositions comprising placental stem cells and platelet rich plasma, and methods of use thereof |
| AU2011352036A1 (en) * | 2010-12-31 | 2013-07-18 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
| DK2970883T3 (da) * | 2013-03-14 | 2021-08-09 | Celularity Inc | Forbedrede placenta stamceller og bruge deraf |
-
2013
- 2013-12-13 JP JP2015547970A patent/JP2016502844A/ja active Pending
- 2013-12-13 AU AU2013359076A patent/AU2013359076A1/en not_active Abandoned
- 2013-12-13 EP EP13862498.6A patent/EP2938196B1/en not_active Not-in-force
- 2013-12-13 EP EP19165534.9A patent/EP3556215A1/en not_active Withdrawn
- 2013-12-13 US US14/651,891 patent/US20150307879A1/en not_active Abandoned
- 2013-12-13 CA CA2895106A patent/CA2895106C/en active Active
- 2013-12-13 CN CN202110724603.6A patent/CN113481164A/zh active Pending
- 2013-12-13 CN CN201380072901.5A patent/CN105283075A/zh active Pending
- 2013-12-13 WO PCT/US2013/074892 patent/WO2014093753A1/en not_active Ceased
-
2018
- 2018-11-30 JP JP2018224316A patent/JP2019068814A/ja active Pending
-
2020
- 2020-11-06 JP JP2020185486A patent/JP2021045133A/ja not_active Withdrawn
-
2022
- 2022-07-14 JP JP2022112849A patent/JP2022160451A/ja active Pending
-
2024
- 2024-07-01 JP JP2024105938A patent/JP2024153631A/ja active Pending
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