JP2018538511A5 - - Google Patents
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- JP2018538511A5 JP2018538511A5 JP2018513641A JP2018513641A JP2018538511A5 JP 2018538511 A5 JP2018538511 A5 JP 2018538511A5 JP 2018513641 A JP2018513641 A JP 2018513641A JP 2018513641 A JP2018513641 A JP 2018513641A JP 2018538511 A5 JP2018538511 A5 JP 2018538511A5
- Authority
- JP
- Japan
- Prior art keywords
- isotope
- compound
- isotopes
- enriched
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 22
- 229910052739 hydrogen Inorganic materials 0.000 claims 12
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 11
- 238000000034 method Methods 0.000 claims 8
- 239000001257 hydrogen Substances 0.000 claims 6
- 125000004429 atom Chemical group 0.000 claims 5
- 125000003277 amino group Chemical group 0.000 claims 4
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 4
- 238000004949 mass spectrometry Methods 0.000 claims 4
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 4
- 125000002723 alicyclic group Chemical group 0.000 claims 3
- 125000003118 aryl group Chemical group 0.000 claims 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 239000003205 fragrance Substances 0.000 claims 3
- 125000005647 linker group Chemical group 0.000 claims 3
- 239000002207 metabolite Substances 0.000 claims 3
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 239000001301 oxygen Substances 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 230000000155 isotopic effect Effects 0.000 claims 2
- 238000002372 labelling Methods 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562241590P | 2015-10-14 | 2015-10-14 | |
| US62/241,590 | 2015-10-14 | ||
| PCT/US2016/057156 WO2017066650A1 (en) | 2015-10-14 | 2016-10-14 | Mass defect-based multiplex dimethyl pyrimidinyl ornithine (dipyro) tags for high-throughput quantitative proteomics and peptidomics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018538511A JP2018538511A (ja) | 2018-12-27 |
| JP2018538511A5 true JP2018538511A5 (enExample) | 2019-11-21 |
Family
ID=58518198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018513641A Pending JP2018538511A (ja) | 2015-10-14 | 2016-10-14 | 高スループット定量的プロテオミクス及びペプチドミクスのための質量欠損ベースの多重化ジメチルピリミジニルオルニチン（ｄｉｐｙｒｏ）タグ |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11408897B2 (enExample) |
| EP (1) | EP3362438A4 (enExample) |
| JP (1) | JP2018538511A (enExample) |
| AU (1) | AU2016338691A1 (enExample) |
| CA (1) | CA2999331A1 (enExample) |
| WO (1) | WO2017066650A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11119127B2 (en) | 2017-08-01 | 2021-09-14 | Carlos Moreno | Method and apparatus for non-intrusive program tracing with bandwidth reduction for embedded computing systems |
| WO2019096852A1 (en) * | 2017-11-14 | 2019-05-23 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Uses of isobaric tags in mass spectrometry |
| CN112146967A (zh) * | 2019-06-28 | 2020-12-29 | Fei 公司 | 用于制备和递送用于带电粒子分析的生物样品的系统和方法 |
| US20220373558A1 (en) * | 2019-09-19 | 2022-11-24 | Janssen Biotech, Inc. | Materials and methods for differential characterization of molecular conjugates and conjugation |
| US12111322B2 (en) | 2019-12-13 | 2024-10-08 | Wisconsin Alumni Research Foundation | Mass spectrometry-based method for simultaneous qualitative and quantitative protein citrullination analysis of complex biological samples |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK71801C (da) | 1949-03-09 | 1950-12-04 | Landmand Aage Pallesen Fasterh | Kartoffeloptagemaskine. |
| EP1451207B1 (en) | 2001-11-05 | 2009-08-26 | Irm Llc | Labeling reagent and methods of use |
| US20070048752A1 (en) | 2004-07-12 | 2007-03-01 | Applera Corporation | Mass tags for quantitative analyses |
| US20060172319A1 (en) | 2004-07-12 | 2006-08-03 | Applera Corporation | Mass tags for quantitative analyses |
| GB0515323D0 (en) | 2005-07-26 | 2005-08-31 | Electrophoretics Ltd | Mass labels |
| US9388132B2 (en) * | 2011-09-15 | 2016-07-12 | Wisconsin Alumni Research Foundation | Isobaric tandem mass tags for quantitative proteomics and peptidomics |
| US9366678B2 (en) * | 2012-10-25 | 2016-06-14 | Wisconsin Alumni Research Foundation | Neutron encoded mass tags for analyte quantification |
-
2016
- 2016-10-14 WO PCT/US2016/057156 patent/WO2017066650A1/en not_active Ceased
- 2016-10-14 AU AU2016338691A patent/AU2016338691A1/en not_active Abandoned
- 2016-10-14 US US15/768,299 patent/US11408897B2/en active Active
- 2016-10-14 EP EP16856326.0A patent/EP3362438A4/en not_active Withdrawn
- 2016-10-14 CA CA2999331A patent/CA2999331A1/en not_active Abandoned
- 2016-10-14 JP JP2018513641A patent/JP2018538511A/ja active Pending
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