JP2018537111A5 - - Google Patents
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- JP2018537111A5 JP2018537111A5 JP2018531169A JP2018531169A JP2018537111A5 JP 2018537111 A5 JP2018537111 A5 JP 2018537111A5 JP 2018531169 A JP2018531169 A JP 2018531169A JP 2018531169 A JP2018531169 A JP 2018531169A JP 2018537111 A5 JP2018537111 A5 JP 2018537111A5
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- JP
- Japan
- Prior art keywords
- seq
- positions
- amino acid
- mutations
- acid positions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920001184 polypeptide Polymers 0.000 claims description 15
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 15
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 15
- 230000004927 fusion Effects 0.000 claims description 13
- 102200074510 rs2015352 Human genes 0.000 claims description 11
- 102220517055 Transcriptional regulator PINT87aa_I11L_mutation Human genes 0.000 claims description 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 31
- 230000035772 mutation Effects 0.000 claims 26
- 235000014113 dietary fatty acids Nutrition 0.000 claims 8
- 229930195729 fatty acid Natural products 0.000 claims 8
- 239000000194 fatty acid Substances 0.000 claims 8
- 150000004665 fatty acids Chemical class 0.000 claims 8
- 102220245308 rs1555601006 Human genes 0.000 claims 4
- 102220557155 Alstrom syndrome protein 1_N61L_mutation Human genes 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 102200059965 rs61753185 Human genes 0.000 claims 2
- 102100022089 Acyl-[acyl-carrier-protein] hydrolase Human genes 0.000 claims 1
- 102100037611 Lysophospholipase Human genes 0.000 claims 1
- 102000005488 Thioesterase Human genes 0.000 claims 1
- 102220367838 c.28G>T Human genes 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 108020002982 thioesterase Proteins 0.000 claims 1
- 230000003197 catalytic effect Effects 0.000 description 3
- 150000003278 haem Chemical group 0.000 description 2
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 125000000539 amino acid group Chemical group 0.000 description 1
- 102000034238 globular proteins Human genes 0.000 description 1
- 108091005896 globular proteins Proteins 0.000 description 1
- 230000033444 hydroxylation Effects 0.000 description 1
- 238000005805 hydroxylation reaction Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021164702A JP7458358B2 (ja) | 2015-12-15 | 2021-10-06 | 改良された特性を有するω－ヒドロキシラーゼ関連融合ポリペプチドバリアント |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2015/079832 WO2017101987A1 (en) | 2015-12-15 | 2015-12-15 | Omega-hydroxylase-related fusion polypeptide variants with improved properties |
| EPPCT/EP2015/079832 | 2015-12-15 | ||
| PCT/US2016/066405 WO2017106205A1 (en) | 2015-12-15 | 2016-12-13 | Omega-hydroxylase-related fusion polypeptide variants with improved properties |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021164702A Division JP7458358B2 (ja) | 2015-12-15 | 2021-10-06 | 改良された特性を有するω－ヒドロキシラーゼ関連融合ポリペプチドバリアント |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018537111A JP2018537111A (ja) | 2018-12-20 |
| JP2018537111A5 true JP2018537111A5 (cg-RX-API-DMAC7.html) | 2021-05-13 |
| JP6957469B2 JP6957469B2 (ja) | 2021-11-02 |
Family
ID=55022448
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018531169A Active JP6957469B2 (ja) | 2015-12-15 | 2016-12-13 | 改良された特性を有するω−ヒドロキシラーゼ関連融合ポリペプチドバリアント |
| JP2021164702A Active JP7458358B2 (ja) | 2015-12-15 | 2021-10-06 | 改良された特性を有するω－ヒドロキシラーゼ関連融合ポリペプチドバリアント |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021164702A Active JP7458358B2 (ja) | 2015-12-15 | 2021-10-06 | 改良された特性を有するω－ヒドロキシラーゼ関連融合ポリペプチドバリアント |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10787648B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3390620B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6957469B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR20250117480A (cg-RX-API-DMAC7.html) |
| CN (3) | CN108699536B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016370490B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3008836A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2908400T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2018007298A (cg-RX-API-DMAC7.html) |
| MY (2) | MY194277A (cg-RX-API-DMAC7.html) |
| SI (1) | SI3390620T1 (cg-RX-API-DMAC7.html) |
| WO (2) | WO2017101987A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX372803B (es) | 2014-06-16 | 2020-07-03 | Genomatica Inc | Polipeptidos de fusion relacionados con omega-hidroxilasa con propiedades mejoradas. |
| WO2017101987A1 (en) | 2015-12-15 | 2017-06-22 | REG Life Sciences, LLC | Omega-hydroxylase-related fusion polypeptide variants with improved properties |
| EP3810778A4 (en) * | 2018-05-10 | 2022-06-29 | Genomatica, Inc. | Multifunctional fatty acid derivatives and biosynthesis thereof |
| KR102516485B1 (ko) | 2018-10-31 | 2023-04-03 | 삼성전자주식회사 | 폴더블 하우징을 포함하는 전자 장치 |
Family Cites Families (58)
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| US5602030A (en) | 1994-03-28 | 1997-02-11 | University Of Florida Research Foundation | Recombinant glucose uptake system |
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| EP1501784B1 (en) | 2002-04-29 | 2019-03-13 | Dow Global Technologies LLC | Integrated chemical processes for industrial utilization of seed oils |
| JPWO2006051729A1 (ja) | 2004-11-10 | 2008-05-29 | 株式会社海洋バイオテクノロジー研究所 | Ｐ４５０遺伝子の単離法 |
| US20100242345A1 (en) | 2006-05-19 | 2010-09-30 | LS9, Inc | Production of fatty acids & derivatives thereof |
| EP2194119A3 (en) | 2006-05-19 | 2010-09-22 | LS9, Inc. | Production of fatty acids and derivatives thereof |
| US8110670B2 (en) | 2006-05-19 | 2012-02-07 | Ls9, Inc. | Enhanced production of fatty acid derivatives |
| CN102123979A (zh) | 2006-10-13 | 2011-07-13 | 埃莱文斯可更新科学公司 | 通过烯烃复分解由内烯烃合成末端烯烃的方法 |
| WO2008140468A2 (en) | 2006-10-13 | 2008-11-20 | Elevance Renewable Sciences, Inc. | METHODS OF MAKING α, ω -DICARBOXYLIC ACID ALKENE DERIVATIVES BY METATHESIS |
| WO2008113041A2 (en) | 2007-03-14 | 2008-09-18 | Ls9, Inc. | Process for producing low molecular weight hydrocarbons from renewable resources |
| CA2678915C (en) | 2007-03-28 | 2019-04-09 | Ls9, Inc. | Enhanced production of fatty acid derivatives |
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| CA2679085C (en) | 2007-05-22 | 2018-04-10 | Ls9, Inc. | Hydrocarbon-producing genes and methods of their use |
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| WO2009009391A2 (en) | 2007-07-06 | 2009-01-15 | Ls9, Inc. | Systems and methods for the production of fatty esters |
| FR2921362B1 (fr) | 2007-09-20 | 2012-09-21 | Arkema France | Procede de synthese d'acides gras omega-insatures |
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| TWI351779B (en) | 2007-12-03 | 2011-11-01 | Advance Smart Ind Ltd | Apparatus and method for correcting residual capac |
| WO2009085278A1 (en) | 2007-12-21 | 2009-07-09 | Ls9, Inc. | Methods and compositions for producing olefins |
| CN102027108A (zh) | 2008-05-16 | 2011-04-20 | Ls9公司 | 产生碳氢化合物的方法和组合物 |
| US8232924B2 (en) | 2008-05-23 | 2012-07-31 | Alliant Techsystems Inc. | Broadband patch antenna and antenna system |
| US8273694B2 (en) | 2008-07-28 | 2012-09-25 | Jeffrey A Brown | Synthetic compositions obtained from algae |
| US20100071259A1 (en) | 2008-08-18 | 2010-03-25 | Ls9, Inc. | Systems and methods for production of mixed fatty esters |
| TW201016657A (en) | 2008-08-28 | 2010-05-01 | Mitsui Chemicals Inc | Olefin production process |
| CA3038491A1 (en) | 2008-10-07 | 2010-04-15 | REG Life Sciences, LLC | Bacterial host cells engineered to express a carboxylic acid reductase and a thioesterase |
| EP2796559B1 (en) | 2008-10-28 | 2018-09-12 | REG Life Sciences, LLC | Microbial cell for producing fatty alcohols |
| US7989875B2 (en) | 2008-11-24 | 2011-08-02 | Nxp B.V. | BiCMOS integration of multiple-times-programmable non-volatile memories |
| US9175234B2 (en) | 2008-12-23 | 2015-11-03 | REG Life Sciences, LLC | Methods and compositions related to thioesterase enzymes |
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| WO2017101987A1 (en) * | 2015-12-15 | 2017-06-22 | REG Life Sciences, LLC | Omega-hydroxylase-related fusion polypeptide variants with improved properties |
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2015
- 2015-12-15 WO PCT/EP2015/079832 patent/WO2017101987A1/en not_active Ceased
-
2016
- 2016-12-13 CN CN201680081302.3A patent/CN108699536B/zh active Active
- 2016-12-13 AU AU2016370490A patent/AU2016370490B2/en not_active Ceased
- 2016-12-13 KR KR1020257025119A patent/KR20250117480A/ko active Pending
- 2016-12-13 CN CN202210859052.9A patent/CN116334012A/zh active Pending
- 2016-12-13 KR KR1020187020089A patent/KR102840377B1/ko active Active
- 2016-12-13 SI SI201631502T patent/SI3390620T1/sl unknown
- 2016-12-13 CA CA3008836A patent/CA3008836A1/en active Pending
- 2016-12-13 CN CN202210871940.2A patent/CN116334013A/zh active Pending
- 2016-12-13 EP EP16836213.5A patent/EP3390620B1/en active Active
- 2016-12-13 MY MYPI2018000942A patent/MY194277A/en unknown
- 2016-12-13 EP EP21209002.1A patent/EP4026899A1/en active Pending
- 2016-12-13 MX MX2018007298A patent/MX2018007298A/es unknown
- 2016-12-13 JP JP2018531169A patent/JP6957469B2/ja active Active
- 2016-12-13 WO PCT/US2016/066405 patent/WO2017106205A1/en not_active Ceased
- 2016-12-13 US US16/063,198 patent/US10787648B2/en active Active
- 2016-12-13 ES ES16836213T patent/ES2908400T3/es active Active
- 2016-12-13 MY MYPI2021004987A patent/MY196584A/en unknown
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2020
- 2020-08-24 US US17/001,015 patent/US11384341B2/en active Active
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2021
- 2021-10-06 JP JP2021164702A patent/JP7458358B2/ja active Active
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2022
- 2022-06-07 US US17/834,681 patent/US12180515B2/en active Active