JP2018535996A5 - - Google Patents

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Publication number
JP2018535996A5
JP2018535996A5 JP2018528591A JP2018528591A JP2018535996A5 JP 2018535996 A5 JP2018535996 A5 JP 2018535996A5 JP 2018528591 A JP2018528591 A JP 2018528591A JP 2018528591 A JP2018528591 A JP 2018528591A JP 2018535996 A5 JP2018535996 A5 JP 2018535996A5
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JP
Japan
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pharmaceutically acceptable
composition
acceptable salt
effective amount
administered
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JP2018528591A
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English (en)
Japanese (ja)
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JP2018535996A (ja
JP6944936B2 (ja
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Priority claimed from PCT/US2016/064824 external-priority patent/WO2017096303A2/en
Publication of JP2018535996A publication Critical patent/JP2018535996A/ja
Publication of JP2018535996A5 publication Critical patent/JP2018535996A5/ja
Application granted granted Critical
Publication of JP6944936B2 publication Critical patent/JP6944936B2/ja
Expired - Fee Related legal-status Critical Current
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JP2018528591A 2015-12-04 2016-12-02 血液癌を処置するためのセルデュラチニブ Expired - Fee Related JP6944936B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562263582P 2015-12-04 2015-12-04
US62/263,582 2015-12-04
US201662342727P 2016-05-27 2016-05-27
US201662342755P 2016-05-27 2016-05-27
US62/342,755 2016-05-27
US62/342,727 2016-05-27
US201662371145P 2016-08-04 2016-08-04
US62/371,145 2016-08-04
PCT/US2016/064824 WO2017096303A2 (en) 2015-12-04 2016-12-02 Cerdulatinib for treating hematological cancers

Publications (3)

Publication Number Publication Date
JP2018535996A JP2018535996A (ja) 2018-12-06
JP2018535996A5 true JP2018535996A5 (enExample) 2020-01-09
JP6944936B2 JP6944936B2 (ja) 2021-10-06

Family

ID=57614468

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018528591A Expired - Fee Related JP6944936B2 (ja) 2015-12-04 2016-12-02 血液癌を処置するためのセルデュラチニブ

Country Status (8)

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US (2) US10736895B2 (enExample)
EP (1) EP3383396B1 (enExample)
JP (1) JP6944936B2 (enExample)
CN (1) CN108367006B (enExample)
AU (1) AU2016363005A1 (enExample)
CA (1) CA2950640A1 (enExample)
ES (1) ES2959692T3 (enExample)
WO (1) WO2017096303A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016196385A1 (en) 2015-05-29 2016-12-08 Portola Pharmaceuticals, Inc. Cerdulatinib for the treatment of b-cell malignancies
ES2913119T3 (es) 2015-08-12 2022-05-31 Portola Pharm Inc Cerdulatinib para tratar mieloma
BR112020013976A2 (pt) * 2018-01-09 2020-12-08 Dermavant Sciences GmbH Composições farmacêuticas para pele tópicas que contêm cerdulatinibe e usos das mesmas
KR20210003789A (ko) * 2018-05-04 2021-01-12 포톨라 파마슈티컬스, 인코포레이티드 림프종을 치료하는 방법
US10851087B2 (en) 2018-05-04 2020-12-01 Portola Pharmaceuticals, Inc. Synthesis of cerdulatinib
WO2019213606A2 (en) 2018-05-04 2019-11-07 Portola Pharmaceuticals, Inc. Solid forms of cerdulatinib
US20200262925A1 (en) * 2019-02-15 2020-08-20 Janssen Biotech, Inc. Combination Therapy For Treatment Of B-Cell Malignancies
WO2021242614A1 (en) * 2020-05-26 2021-12-02 Alexion Pharmaceuticals, Inc. Circulating b cell subpopulations in indolent b cell lymphoma

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE401312T1 (de) 1997-12-15 2008-08-15 Astellas Pharma Inc Pyrimidin-5-carboxamid-derivate
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
ES2373226T3 (es) 2002-06-28 2012-02-01 Astellas Pharma Inc. Derivado de diaminopirimidincarboxamida.
WO2008009458A1 (en) 2006-07-21 2008-01-24 Novartis Ag 2, 4 -di (arylaminio) -pyrimidine-5-carboxamide compounds as jak kinases inhibitors
EP2529621B1 (en) 2006-09-22 2016-10-05 Pharmacyclics LLC Inhibitors of bruton's tyrosine kinase
CA2723205C (en) 2008-04-16 2017-03-14 Portola Pharmaceuticals, Inc. 2,6-diamino-pyrimidin-5-yl-carboxamides as syk or jak kinase inhibitors
US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
WO2010129802A1 (en) 2009-05-06 2010-11-11 Portola Pharmaceuticals, Inc. Inhibitors of jak
ES2546294T7 (es) 2009-05-26 2024-06-06 Abbvie Ireland Unlimited Co Agentes inductores de la apoptosis para el tratamiento de cáncer y enfermedades inmunitarias y autoinmunitarias
US20110130415A1 (en) 2009-12-01 2011-06-02 Rajinder Singh Protein kinase c inhibitors and uses thereof
US9398308B2 (en) 2010-07-28 2016-07-19 Qualcomm Incorporated Coding motion prediction direction in video coding
WO2012045020A1 (en) 2010-09-30 2012-04-05 Portola Pharmaceuticals, Inc. Combinations of 4-(cyclopropylamino)-2-(4-(4-(ethylsulfonyl)piperazin-1-yl)phenylamino)pyrimidine-5-carboxamide and fludarabine
WO2012071336A1 (en) 2010-11-23 2012-05-31 Abbott Laboratories Salts and crystalline forms of an apoptosis-inducing agent
WO2013023119A1 (en) 2011-08-10 2013-02-14 Novartis Pharma Ag JAK P13K/mTOR COMBINATION THERAPY
HK1206073A1 (en) 2012-07-24 2015-12-31 药品循环有限责任公司 Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk)
WO2014058921A2 (en) 2012-10-08 2014-04-17 Portola Pharmaceuticals, Inc. Substituted pyrimidinyl kinase inhibitors
SG11201503459SA (en) 2012-11-02 2015-06-29 Pharmacyclics Inc Tec family kinase inhibitor adjuvant therapy
EP3191098A4 (en) 2014-09-12 2018-04-25 G1 Therapeutics, Inc. Combinations and dosing regimes to treat rb-positive tumors
WO2016196385A1 (en) 2015-05-29 2016-12-08 Portola Pharmaceuticals, Inc. Cerdulatinib for the treatment of b-cell malignancies
ES2913119T3 (es) 2015-08-12 2022-05-31 Portola Pharm Inc Cerdulatinib para tratar mieloma
WO2019213606A2 (en) 2018-05-04 2019-11-07 Portola Pharmaceuticals, Inc. Solid forms of cerdulatinib

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