JP2018532763A5 - - Google Patents
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- Publication number
- JP2018532763A5 JP2018532763A5 JP2018523444A JP2018523444A JP2018532763A5 JP 2018532763 A5 JP2018532763 A5 JP 2018532763A5 JP 2018523444 A JP2018523444 A JP 2018523444A JP 2018523444 A JP2018523444 A JP 2018523444A JP 2018532763 A5 JP2018532763 A5 JP 2018532763A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- subject
- administered
- mutant polypeptide
- htcbs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022002966A JP7482914B2 (ja) | 2015-11-09 | 2022-01-12 | ホモシスチン尿症の治療する組成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/935,690 | 2015-11-09 | ||
| US14/935,690 US9675678B2 (en) | 2013-01-29 | 2015-11-09 | Compositions and methods for treatment of homocystinuria |
| PCT/US2016/061050 WO2017083327A1 (en) | 2015-11-09 | 2016-11-09 | Compositions and methods for treatment of homocystinuria |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022002966A Division JP7482914B2 (ja) | 2015-11-09 | 2022-01-12 | ホモシスチン尿症の治療する組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018532763A JP2018532763A (ja) | 2018-11-08 |
| JP2018532763A5 true JP2018532763A5 (https=) | 2019-10-31 |
| JP7009364B2 JP7009364B2 (ja) | 2022-02-10 |
Family
ID=58696136
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018523444A Active JP7009364B2 (ja) | 2015-11-09 | 2016-11-09 | ホモシスチン尿症の治療する組成物および方法 |
| JP2022002966A Active JP7482914B2 (ja) | 2015-11-09 | 2022-01-12 | ホモシスチン尿症の治療する組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022002966A Active JP7482914B2 (ja) | 2015-11-09 | 2022-01-12 | ホモシスチン尿症の治療する組成物および方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US11077175B2 (https=) |
| EP (3) | EP3373922B1 (https=) |
| JP (2) | JP7009364B2 (https=) |
| KR (1) | KR102819396B1 (https=) |
| CN (2) | CN115920016A (https=) |
| AU (2) | AU2016354030B2 (https=) |
| BR (1) | BR112018007768A2 (https=) |
| CY (1) | CY1125113T1 (https=) |
| DK (2) | DK3373922T3 (https=) |
| ES (2) | ES2909914T3 (https=) |
| FI (1) | FI3998067T3 (https=) |
| HR (2) | HRP20220407T1 (https=) |
| HU (2) | HUE058749T2 (https=) |
| IL (2) | IL302198A (https=) |
| LT (2) | LT3998067T (https=) |
| MX (1) | MX2018005312A (https=) |
| NZ (1) | NZ741552A (https=) |
| PL (2) | PL3998067T3 (https=) |
| PT (2) | PT3373922T (https=) |
| RS (2) | RS63070B1 (https=) |
| SG (1) | SG10201912972SA (https=) |
| SI (2) | SI3373922T1 (https=) |
| SM (2) | SMT202400463T1 (https=) |
| WO (1) | WO2017083327A1 (https=) |
| ZA (1) | ZA201802376B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9675678B2 (en) | 2013-01-29 | 2017-06-13 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for treatment of homocystinuria |
| EP3373922B1 (en) | 2015-11-09 | 2022-01-05 | The Regents of The University of Colorado, A Body Corporate | Compositions and methods for use in the treatment of homocystinuria |
| EP3612214A4 (en) * | 2017-04-17 | 2021-01-20 | The Regents of the University of Colorado, A Body Corporate | ENZYME REPLACEMENT THERAPY OPTIMIZATION FOR THE TREATMENT OF HOMOCYSTINURIA |
| HRP20251579T1 (hr) * | 2019-06-26 | 2026-01-30 | Travere Therapeutics Switzerland Gmbh | Pegilirana cistationin beta sintaza za enzimsku terapiju za liječenje homocistinurije |
| MX2022002571A (es) * | 2019-09-03 | 2022-05-06 | Travere Therapeutics Switzerland Gmbh | Terapia enzimatica con cistationina beta-sintasa para el tratamiento de niveles elevados de homocisteina. |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS555429A (en) * | 1978-06-23 | 1980-01-16 | Nissan Motor Co Ltd | Pressure regulator for fuel injection type gasoline engine |
| JPS5576559A (en) | 1978-12-01 | 1980-06-09 | Chiyou Lsi Gijutsu Kenkyu Kumiai | Electron beam fine adjusting device |
| US5656425A (en) | 1993-08-17 | 1997-08-12 | Regents Of The University Of Colorado | Screening for mutations by expressing cDNA segments |
| US5523225A (en) | 1993-09-13 | 1996-06-04 | Regents Of The University Of Colorado | DNA sequence encoding human cystathionine β-synthase |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| US5919455A (en) | 1993-10-27 | 1999-07-06 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| US5730990A (en) | 1994-06-24 | 1998-03-24 | Enzon, Inc. | Non-antigenic amine derived polymers and polymer conjugates |
| US5635375A (en) | 1995-01-09 | 1997-06-03 | Regents Of The University Of Colorado | Method of increasing the yield and heme saturation of cystathione β-synthase |
| CA2217696A1 (en) | 1995-04-25 | 1996-10-31 | Oridigm Corporation | S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy |
| US5705151A (en) | 1995-05-18 | 1998-01-06 | National Jewish Center For Immunology & Respiratory Medicine | Gene therapy for T cell regulation |
| US6153655A (en) | 1998-04-17 | 2000-11-28 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| WO1999055377A2 (en) | 1998-04-28 | 1999-11-04 | Applied Research Systems Ars Holding N.V. | Polyol-ifn-beta conjugates |
| US6174696B1 (en) | 1999-11-12 | 2001-01-16 | Genzyme Corporation | Method for the determination of homocysteine |
| GB2368641B (en) | 1999-07-06 | 2004-10-06 | Gen Atomics | Methods and compositions for assaying analytes |
| US6653062B1 (en) | 2000-07-26 | 2003-11-25 | Wisconsin Alumni Research Foundation | Preservation and storage medium for biological materials |
| US20030091543A1 (en) | 2001-10-26 | 2003-05-15 | Klein Matthew B. | Therapeutic cell preparation grafts and methods of use thereof |
| AU2003251550A1 (en) | 2002-06-17 | 2003-12-31 | The Regents Of The University Of Colorado | HUMAN CYSTATHIONINE Beta-SYNTHASE VARIANTS AND METHODS OF PRODU CTION THEREOF |
| GB0216001D0 (en) | 2002-07-10 | 2002-08-21 | Nat Blood Authority | Process and composition |
| EP1396537A1 (en) * | 2002-09-04 | 2004-03-10 | Avidis SA | Treatment of elevated plasma homocysteine |
| KR20060065663A (ko) | 2003-07-31 | 2006-06-14 | 안티캔서, 인코포레이티드 | 생체 내에서의 유효성 향상을 위한, ＰＥＧ-ｒＭＥＴ아제와조합된 ＰＬＰ의 용도 |
| CN1552905A (zh) | 2003-12-18 | 2004-12-08 | 中国农业科学院茶叶研究所 | 一类茶树胱硫醚-γ-合成酶特异表达序列标签及其生物芯片 |
| US8500720B2 (en) | 2005-05-09 | 2013-08-06 | Medtronic, Inc | Method and apparatus for treatment of cardiac disorders |
| US20070010492A1 (en) | 2005-07-11 | 2007-01-11 | Generale Robert J | Composition and method for reducing homocysteine caused by drugs containing methyl compounds |
| EP1878739A1 (en) | 2006-07-14 | 2008-01-16 | LEK Pharmaceuticals D.D. | One step IMAC (MCAC) purification of proteins |
| JP6041454B2 (ja) * | 2007-03-15 | 2016-12-07 | 株式会社 Ｄｎａセキュリティー研究所 | Ｄｎａ含有インク組成物 |
| JP5074146B2 (ja) | 2007-03-30 | 2012-11-14 | オリンパス株式会社 | カプセル型医療装置 |
| CN101322840A (zh) | 2008-05-28 | 2008-12-17 | 中国人民解放军军事医学科学院卫生学环境医学研究所 | 一种人胱硫醚β-合成酶重组蛋白及应用 |
| WO2011025964A2 (en) | 2009-08-29 | 2011-03-03 | Abbott Laboratories | Therapeutic dll4 binding proteins |
| EP2531597B1 (en) | 2010-02-04 | 2021-01-06 | AEMase, Inc. | Engineered enzymes with methionine-gamma-lyase enzymes and pharmacological preparations therof |
| CA2803668A1 (en) | 2010-07-01 | 2012-01-05 | Isis Innovation Limited | Treatment of cognitive disorders |
| US9034318B2 (en) | 2011-08-30 | 2015-05-19 | The Regents Of The University Of Colorado, A Body Corporate | Chemically modified cystathionine beta-synthase enzyme for treatment of homocystinuria |
| US9243239B2 (en) | 2012-03-26 | 2016-01-26 | The Regents Of The University Of Colorado, A Body Corporate | Purification of cystathionine beta-synthase |
| US9675678B2 (en) | 2013-01-29 | 2017-06-13 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for treatment of homocystinuria |
| WO2015033279A1 (en) * | 2013-09-04 | 2015-03-12 | Mahesh Kandula | Compositions and methods for the treatment of homocystinuria |
| JP6987741B2 (ja) | 2015-07-24 | 2022-01-05 | ハンミ ファーマシューティカル カンパニー リミテッド | 生理活性ポリペプチド結合体の製造方法 |
| EP3373922B1 (en) | 2015-11-09 | 2022-01-05 | The Regents of The University of Colorado, A Body Corporate | Compositions and methods for use in the treatment of homocystinuria |
| EP3612214A4 (en) | 2017-04-17 | 2021-01-20 | The Regents of the University of Colorado, A Body Corporate | ENZYME REPLACEMENT THERAPY OPTIMIZATION FOR THE TREATMENT OF HOMOCYSTINURIA |
| JP7002314B2 (ja) * | 2017-12-13 | 2022-02-10 | 株式会社ブリヂストン | 空気入りタイヤ |
| HRP20251579T1 (hr) | 2019-06-26 | 2026-01-30 | Travere Therapeutics Switzerland Gmbh | Pegilirana cistationin beta sintaza za enzimsku terapiju za liječenje homocistinurije |
| MX2022002571A (es) | 2019-09-03 | 2022-05-06 | Travere Therapeutics Switzerland Gmbh | Terapia enzimatica con cistationina beta-sintasa para el tratamiento de niveles elevados de homocisteina. |
-
2016
- 2016-11-09 EP EP16864878.0A patent/EP3373922B1/en active Active
- 2016-11-09 RS RS20220308A patent/RS63070B1/sr unknown
- 2016-11-09 KR KR1020187013230A patent/KR102819396B1/ko active Active
- 2016-11-09 EP EP21204193.3A patent/EP3998067B1/en active Active
- 2016-11-09 SI SI201631487T patent/SI3373922T1/sl unknown
- 2016-11-09 LT LTEP21204193.3T patent/LT3998067T/lt unknown
- 2016-11-09 DK DK16864878.0T patent/DK3373922T3/da active
- 2016-11-09 IL IL302198A patent/IL302198A/en unknown
- 2016-11-09 JP JP2018523444A patent/JP7009364B2/ja active Active
- 2016-11-09 HR HRP20220407TT patent/HRP20220407T1/hr unknown
- 2016-11-09 IL IL258487A patent/IL258487B2/en unknown
- 2016-11-09 BR BR112018007768A patent/BR112018007768A2/pt not_active Application Discontinuation
- 2016-11-09 AU AU2016354030A patent/AU2016354030B2/en active Active
- 2016-11-09 EP EP24199181.9A patent/EP4487914A3/en active Pending
- 2016-11-09 SM SM20240463T patent/SMT202400463T1/it unknown
- 2016-11-09 SM SM20220151T patent/SMT202200151T1/it unknown
- 2016-11-09 WO PCT/US2016/061050 patent/WO2017083327A1/en not_active Ceased
- 2016-11-09 HU HUE16864878A patent/HUE058749T2/hu unknown
- 2016-11-09 CN CN202211006580.6A patent/CN115920016A/zh active Pending
- 2016-11-09 PT PT168648780T patent/PT3373922T/pt unknown
- 2016-11-09 SG SG10201912972SA patent/SG10201912972SA/en unknown
- 2016-11-09 PL PL21204193.3T patent/PL3998067T3/pl unknown
- 2016-11-09 ES ES16864878T patent/ES2909914T3/es active Active
- 2016-11-09 PT PT212041933T patent/PT3998067T/pt unknown
- 2016-11-09 DK DK21204193.3T patent/DK3998067T3/da active
- 2016-11-09 FI FIEP21204193.3T patent/FI3998067T3/fi active
- 2016-11-09 HU HUE21204193A patent/HUE068830T2/hu unknown
- 2016-11-09 MX MX2018005312A patent/MX2018005312A/es unknown
- 2016-11-09 LT LTEPPCT/US2016/061050T patent/LT3373922T/lt unknown
- 2016-11-09 ES ES21204193T patent/ES2994256T3/es active Active
- 2016-11-09 CN CN201680076275.0A patent/CN108472277A/zh active Pending
- 2016-11-09 RS RS20241229A patent/RS66106B1/sr unknown
- 2016-11-09 NZ NZ741552A patent/NZ741552A/en unknown
- 2016-11-09 HR HRP20241491TT patent/HRP20241491T1/hr unknown
- 2016-11-09 SI SI201631858T patent/SI3998067T1/sl unknown
- 2016-11-09 PL PL16864878T patent/PL3373922T3/pl unknown
-
2018
- 2018-04-11 ZA ZA201802376A patent/ZA201802376B/en unknown
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2020
- 2020-03-20 US US16/824,931 patent/US11077175B2/en active Active
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2021
- 2021-06-29 US US17/362,633 patent/US11771745B2/en active Active
-
2022
- 2022-01-12 JP JP2022002966A patent/JP7482914B2/ja active Active
- 2022-04-04 CY CY20221100254T patent/CY1125113T1/el unknown
- 2022-12-12 AU AU2022287540A patent/AU2022287540B2/en active Active
-
2023
- 2023-08-23 US US18/454,701 patent/US12194082B2/en active Active
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