JP2018531046A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018531046A5 JP2018531046A5 JP2018539237A JP2018539237A JP2018531046A5 JP 2018531046 A5 JP2018531046 A5 JP 2018531046A5 JP 2018539237 A JP2018539237 A JP 2018539237A JP 2018539237 A JP2018539237 A JP 2018539237A JP 2018531046 A5 JP2018531046 A5 JP 2018531046A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- inhibitor
- seq
- composition
- based inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562241535P | 2015-10-14 | 2015-10-14 | |
| US62/241,535 | 2015-10-14 | ||
| US201662331795P | 2016-05-04 | 2016-05-04 | |
| US62/331,795 | 2016-05-04 | ||
| PCT/US2016/057164 WO2017066657A1 (en) | 2015-10-14 | 2016-10-14 | Nucleic acid based tia-1 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018531046A JP2018531046A (ja) | 2018-10-25 |
| JP2018531046A6 JP2018531046A6 (ja) | 2018-12-13 |
| JP2018531046A5 true JP2018531046A5 (enExample) | 2019-11-21 |
Family
ID=57209905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018539237A Pending JP2018531046A (ja) | 2015-10-14 | 2016-10-14 | 核酸ベースのｔｉａ−１阻害剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20190142860A1 (enExample) |
| EP (1) | EP3362564B1 (enExample) |
| JP (1) | JP2018531046A (enExample) |
| CA (1) | CA3001853A1 (enExample) |
| WO (1) | WO2017066657A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210236532A1 (en) * | 2018-01-29 | 2021-08-05 | National University Corporation Tokyo Medical And Dental University | Therapeutic agent for frontotemporal lobar degeneration, method for screening therapeutic agent for frontotemporal lobar degeneration and method for treating frontotemporal lobar degeneration |
| CN113196055B (zh) | 2018-10-15 | 2025-06-27 | 马克斯·普朗克科学促进协会 | 用于治疗疾病的化合物及其筛选方法 |
| WO2020089260A1 (en) | 2018-11-01 | 2020-05-07 | F. Hoffmann-La Roche Ag | Antisense oligonucleotides targeting tia1 |
| CN111500694B (zh) * | 2019-01-31 | 2023-02-24 | 中国科学院脑科学与智能技术卓越创新中心 | Baz2b基因作为靶点在缓解衰老中的应用 |
| EP3921650A1 (en) | 2019-02-08 | 2021-12-15 | Dewpoint Therapeutics, Inc. | Methods of characterizing condensate-associated characteristics of compounds and uses thereof |
| WO2021055502A1 (en) * | 2019-09-16 | 2021-03-25 | The Trustees Of Columbia University In The City Of New York | Identification of compounds that inhibit stress granule formation and tau aggregation by targeting tia1 |
| JP2022548695A (ja) | 2019-09-18 | 2022-11-21 | デューポイント セラピューティクス， インコーポレイテッド | 凝縮体関連特異性のスクリーニング方法及びその使用 |
| CN113358617B (zh) * | 2021-06-02 | 2024-03-01 | 重庆大学 | 胞外囊泡富集检测方法 |
| AU2022429793A1 (en) * | 2021-12-27 | 2024-06-27 | Seq Biomarque, Llc. | Methods for diagnosing and/or treating alzheimer's disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5798245A (en) * | 1993-10-07 | 1998-08-25 | Dana-Farber Cancer Institute | TIA-1 binding proteins and isolated complementary DNA encoding the same |
| JP2006507841A (ja) * | 2002-11-14 | 2006-03-09 | ダーマコン， インコーポレイテッド | 機能的ｓｉＲＮＡおよび超機能的ｓｉＲＮＡ |
| US7790867B2 (en) * | 2002-12-05 | 2010-09-07 | Rosetta Genomics Inc. | Vaccinia virus-related nucleic acids and microRNA |
| JP2014501097A (ja) * | 2009-07-06 | 2014-01-20 | アルナイラム ファーマシューティカルズ， インコーポレイテッド | 生物由来物質の産生を高めるための組成物及び方法 |
| CA2752947A1 (en) * | 2011-06-30 | 2012-12-30 | Benjamin J. Blencowe | Foxp1 splice variants and methods and uses thereof |
-
2016
- 2016-10-14 WO PCT/US2016/057164 patent/WO2017066657A1/en not_active Ceased
- 2016-10-14 EP EP16788347.9A patent/EP3362564B1/en active Active
- 2016-10-14 CA CA3001853A patent/CA3001853A1/en not_active Abandoned
- 2016-10-14 JP JP2018539237A patent/JP2018531046A/ja active Pending
- 2016-10-14 US US15/767,906 patent/US20190142860A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10774332B2 (en) | Interfering RNA molecules | |
| CN102666856B (zh) | 定向至RhoA靶基因的双链RNA化合物在制造治疗神经性疼痛的药物中的用途 | |
| ES2646097T3 (es) | Composición para inhibir la expresión de genes y sus usos | |
| CA2862628C (en) | Rna modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy | |
| JP5624474B2 (ja) | オフターゲット効果を極力抑えるとともに、ＲＮＡｉ機構を飽和させない新規なｓｉＲＮＡ構造及びその用途 | |
| EP1389637A1 (en) | Novel forms of interfering RNA molecules | |
| JP2016513976A5 (enExample) | ||
| TW202006138A (zh) | Fubp1抑制劑用於治療b型肝炎病毒感染之用途 | |
| US20250243483A1 (en) | Oligonucleotides | |
| RU2011136531A (ru) | Фармацевтическая композиция для лечения побочных действий посредством приема шпигельмеров | |
| CN117043340A (zh) | 寡核苷酸 | |
| AU2015264957B2 (en) | Further novel forms of interfering rna molecules | |
| TW202516004A (zh) | 調節ｊａｋ１表現之雙股寡核苷酸 | |
| JP2011050381A (ja) | 新規オリゴヌクレオチド誘導体及びそれから成るＮＦ−κＢデコイ | |
| JP2005514946A5 (enExample) | ||
| JP2004313003A (ja) | 大環状標的選択的アンチセンス核酸化合物 |