JP2018529737A5 - - Google Patents
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- Publication number
- JP2018529737A5 JP2018529737A5 JP2018517320A JP2018517320A JP2018529737A5 JP 2018529737 A5 JP2018529737 A5 JP 2018529737A5 JP 2018517320 A JP2018517320 A JP 2018517320A JP 2018517320 A JP2018517320 A JP 2018517320A JP 2018529737 A5 JP2018529737 A5 JP 2018529737A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- salt
- pharmaceutically acceptable
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562237002P | 2015-10-05 | 2015-10-05 | |
| US62/237,002 | 2015-10-05 | ||
| PCT/EP2016/073532 WO2017060180A1 (en) | 2015-10-05 | 2016-10-03 | 2-oxo-1,2-dihydropyridine-3,5-dicarboxamide compounds as bromodomain inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018529737A JP2018529737A (ja) | 2018-10-11 |
| JP2018529737A5 true JP2018529737A5 (OSRAM) | 2019-11-07 |
| JP6832923B2 JP6832923B2 (ja) | 2021-02-24 |
Family
ID=57113320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517320A Expired - Fee Related JP6832923B2 (ja) | 2015-10-05 | 2016-10-03 | ブロモドメイン阻害薬としての２−オキソ−１，２−ジヒドロピリジン−３，５−ジカルボキサミド化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10471050B2 (OSRAM) |
| EP (1) | EP3359531B1 (OSRAM) |
| JP (1) | JP6832923B2 (OSRAM) |
| KR (1) | KR20180059551A (OSRAM) |
| CN (1) | CN108290866B (OSRAM) |
| AU (1) | AU2016334637A1 (OSRAM) |
| BR (1) | BR112018006545A2 (OSRAM) |
| CA (1) | CA2999379A1 (OSRAM) |
| ES (1) | ES2831322T3 (OSRAM) |
| RU (1) | RU2018114705A (OSRAM) |
| WO (1) | WO2017060180A1 (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108137542B (zh) | 2015-09-02 | 2023-10-27 | 葛兰素史克知识产权第二有限公司 | 用作溴结构域抑制剂的吡啶酮二甲酰胺 |
| JP6795588B2 (ja) | 2015-09-22 | 2020-12-02 | グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ | ブロモドメイン阻害薬としての使用のためのピリジノンジカルボキサミド |
| CA2999379A1 (en) | 2015-10-05 | 2017-04-13 | Glaxosmithkline Intellectual Property (No.2) Limited | 2-oxo-1,2-dihydropyridine-3,5-dicarboxamide compounds as bromodomain inhibitors |
| ES2840848T3 (es) | 2016-04-07 | 2021-07-07 | Glaxosmithkline Ip No 2 Ltd | Derivados de piridilo como inhibidores de bromodominio |
| US10844015B2 (en) | 2016-05-24 | 2020-11-24 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
| JOP20190192A1 (ar) | 2017-03-01 | 2019-08-08 | Glaxosmithkline Ip No 2 Ltd | مشتقات بيرازول بوصفها مثبطات برومودومين |
| GB201703282D0 (en) | 2017-03-01 | 2017-04-12 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
| GB201814167D0 (en) | 2018-08-31 | 2018-10-17 | Glaxosmithkline Ip No 2 Ltd | Compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2433158C (en) * | 2000-12-28 | 2011-05-10 | Shionogi & Co., Ltd. | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor |
| ATE447971T1 (de) * | 2002-02-19 | 2009-11-15 | Shionogi & Co | Antipruriginosa |
| ATE380810T1 (de) | 2002-10-09 | 2007-12-15 | Critical Outcome Technologies | Protein-tyrosine-kinase-inhibitoren |
| EP1433788A1 (en) | 2002-12-23 | 2004-06-30 | Aventis Pharma Deutschland GmbH | Pyrazole-derivatives as factor Xa inhibitors |
| GB0919434D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| CA2890983A1 (en) | 2012-11-08 | 2014-05-15 | Bristol-Myers Squibb Company | Heteroaryl substituted pyridyl compounds useful as kinase modulators |
| EP2935253B1 (en) | 2012-12-21 | 2018-08-01 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
| WO2015015318A2 (en) | 2013-07-31 | 2015-02-05 | Zenith Epigenetics Corp. | Novel quinazolinones as bromodomain inhibitors |
| CN108137542B (zh) | 2015-09-02 | 2023-10-27 | 葛兰素史克知识产权第二有限公司 | 用作溴结构域抑制剂的吡啶酮二甲酰胺 |
| CA2999379A1 (en) | 2015-10-05 | 2017-04-13 | Glaxosmithkline Intellectual Property (No.2) Limited | 2-oxo-1,2-dihydropyridine-3,5-dicarboxamide compounds as bromodomain inhibitors |
| ES2840848T3 (es) | 2016-04-07 | 2021-07-07 | Glaxosmithkline Ip No 2 Ltd | Derivados de piridilo como inhibidores de bromodominio |
| US10844015B2 (en) | 2016-05-24 | 2020-11-24 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
-
2016
- 2016-10-03 CA CA2999379A patent/CA2999379A1/en not_active Abandoned
- 2016-10-03 KR KR1020187012923A patent/KR20180059551A/ko not_active Withdrawn
- 2016-10-03 RU RU2018114705A patent/RU2018114705A/ru not_active Application Discontinuation
- 2016-10-03 ES ES16778310T patent/ES2831322T3/es active Active
- 2016-10-03 JP JP2018517320A patent/JP6832923B2/ja not_active Expired - Fee Related
- 2016-10-03 EP EP16778310.9A patent/EP3359531B1/en active Active
- 2016-10-03 WO PCT/EP2016/073532 patent/WO2017060180A1/en not_active Ceased
- 2016-10-03 CN CN201680071214.5A patent/CN108290866B/zh not_active Expired - Fee Related
- 2016-10-03 US US15/766,222 patent/US10471050B2/en not_active Expired - Fee Related
- 2016-10-03 BR BR112018006545A patent/BR112018006545A2/pt active Search and Examination
- 2016-10-03 AU AU2016334637A patent/AU2016334637A1/en not_active Abandoned
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