JP2018528229A5 - - Google Patents
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- Publication number
- JP2018528229A5 JP2018528229A5 JP2018515059A JP2018515059A JP2018528229A5 JP 2018528229 A5 JP2018528229 A5 JP 2018528229A5 JP 2018515059 A JP2018515059 A JP 2018515059A JP 2018515059 A JP2018515059 A JP 2018515059A JP 2018528229 A5 JP2018528229 A5 JP 2018528229A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- salt
- heterocyclyl
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562221649P | 2015-09-22 | 2015-09-22 | |
| US62/221,649 | 2015-09-22 | ||
| PCT/EP2016/072216 WO2017050714A1 (en) | 2015-09-22 | 2016-09-20 | Pyridinone dicarboxamide for use as bromodomain inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018528229A JP2018528229A (ja) | 2018-09-27 |
| JP2018528229A5 true JP2018528229A5 (OSRAM) | 2019-10-17 |
| JP6795588B2 JP6795588B2 (ja) | 2020-12-02 |
Family
ID=56943545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515059A Expired - Fee Related JP6795588B2 (ja) | 2015-09-22 | 2016-09-20 | ブロモドメイン阻害薬としての使用のためのピリジノンジカルボキサミド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10370356B2 (OSRAM) |
| EP (1) | EP3353162A1 (OSRAM) |
| JP (1) | JP6795588B2 (OSRAM) |
| KR (1) | KR20180052762A (OSRAM) |
| CN (1) | CN108137541B (OSRAM) |
| AU (1) | AU2016326864A1 (OSRAM) |
| CA (1) | CA2998545A1 (OSRAM) |
| RU (1) | RU2018112312A (OSRAM) |
| WO (1) | WO2017050714A1 (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10844015B2 (en) | 2016-05-24 | 2020-11-24 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
| SG11202000418XA (en) | 2017-07-18 | 2020-02-27 | Nuvation Bio Inc | Heterocyclic compounds as adenosine antagonists |
| AU2018302178A1 (en) | 2017-07-18 | 2020-02-13 | Nuvation Bio Inc. | 1,8-naphthyridinone compounds and uses thereof |
| GB201716392D0 (en) | 2017-10-06 | 2017-11-22 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
| GB201716369D0 (en) | 2017-10-06 | 2017-11-22 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
| ES2981883T3 (es) * | 2017-10-18 | 2024-10-10 | Biotage Ab | Dispositivo de limpieza de muestra y método para usarlo |
| GB201814167D0 (en) | 2018-08-31 | 2018-10-17 | Glaxosmithkline Ip No 2 Ltd | Compounds |
| AU2019372121A1 (en) | 2018-10-30 | 2021-05-27 | Nuvation Bio Inc. | Heterocyclic compounds as BET inhibitors |
| EP3911323A4 (en) | 2019-01-18 | 2022-11-16 | Nuvation Bio Inc. | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS |
| AU2020207951A1 (en) | 2019-01-18 | 2021-08-26 | Nuvation Bio Inc. | 1,8-naphthyridinone compounds and uses thereof |
| US11584756B2 (en) | 2019-07-02 | 2023-02-21 | Nuvation Bio Inc. | Heterocyclic compounds as BET inhibitors |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9004781D0 (en) | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| CA2433158C (en) | 2000-12-28 | 2011-05-10 | Shionogi & Co., Ltd. | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor |
| ATE447971T1 (de) * | 2002-02-19 | 2009-11-15 | Shionogi & Co | Antipruriginosa |
| GB0211759D0 (en) | 2002-05-22 | 2002-07-03 | Glaxo Group Ltd | Novel compounds |
| ATE380810T1 (de) | 2002-10-09 | 2007-12-15 | Critical Outcome Technologies | Protein-tyrosine-kinase-inhibitoren |
| EP1433788A1 (en) | 2002-12-23 | 2004-06-30 | Aventis Pharma Deutschland GmbH | Pyrazole-derivatives as factor Xa inhibitors |
| ES2388434T3 (es) | 2003-11-03 | 2012-10-15 | Glaxo Group Limited | Dispositivo de administración de fluido |
| GB0919434D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| GB0919423D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| CA2890983A1 (en) | 2012-11-08 | 2014-05-15 | Bristol-Myers Squibb Company | Heteroaryl substituted pyridyl compounds useful as kinase modulators |
| EP2935253B1 (en) * | 2012-12-21 | 2018-08-01 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
| SG11201506245QA (en) | 2013-03-14 | 2015-09-29 | Glaxosmithkline Ip No 2 Ltd | 2,3-disubstituted 1 -acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors |
| TW201516045A (zh) | 2013-07-26 | 2015-05-01 | Hoffmann La Roche | 絲胺酸／蘇胺酸激酶抑制劑 |
| WO2015015318A2 (en) | 2013-07-31 | 2015-02-05 | Zenith Epigenetics Corp. | Novel quinazolinones as bromodomain inhibitors |
| CN108137542B (zh) | 2015-09-02 | 2023-10-27 | 葛兰素史克知识产权第二有限公司 | 用作溴结构域抑制剂的吡啶酮二甲酰胺 |
| CA2999379A1 (en) | 2015-10-05 | 2017-04-13 | Glaxosmithkline Intellectual Property (No.2) Limited | 2-oxo-1,2-dihydropyridine-3,5-dicarboxamide compounds as bromodomain inhibitors |
| ES2840848T3 (es) | 2016-04-07 | 2021-07-07 | Glaxosmithkline Ip No 2 Ltd | Derivados de piridilo como inhibidores de bromodominio |
| US10844015B2 (en) | 2016-05-24 | 2020-11-24 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
-
2016
- 2016-09-20 JP JP2018515059A patent/JP6795588B2/ja not_active Expired - Fee Related
- 2016-09-20 US US15/762,229 patent/US10370356B2/en active Active
- 2016-09-20 KR KR1020187010968A patent/KR20180052762A/ko not_active Withdrawn
- 2016-09-20 CN CN201680054893.5A patent/CN108137541B/zh not_active Expired - Fee Related
- 2016-09-20 RU RU2018112312A patent/RU2018112312A/ru not_active Application Discontinuation
- 2016-09-20 WO PCT/EP2016/072216 patent/WO2017050714A1/en not_active Ceased
- 2016-09-20 AU AU2016326864A patent/AU2016326864A1/en not_active Abandoned
- 2016-09-20 CA CA2998545A patent/CA2998545A1/en not_active Abandoned
- 2016-09-20 EP EP16766979.5A patent/EP3353162A1/en not_active Withdrawn
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