JP2018529690A5 - - Google Patents

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Publication number
JP2018529690A5
JP2018529690A5 JP2018515119A JP2018515119A JP2018529690A5 JP 2018529690 A5 JP2018529690 A5 JP 2018529690A5 JP 2018515119 A JP2018515119 A JP 2018515119A JP 2018515119 A JP2018515119 A JP 2018515119A JP 2018529690 A5 JP2018529690 A5 JP 2018529690A5
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JP
Japan
Prior art keywords
acceptable salt
pharmaceutically acceptable
compound
phenyl
methyl
Prior art date
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JP2018515119A
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English (en)
Japanese (ja)
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JP6635562B2 (ja
JP2018529690A (ja
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Priority claimed from CN201510648342.9A external-priority patent/CN105130888A/zh
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Publication of JP2018529690A publication Critical patent/JP2018529690A/ja
Publication of JP2018529690A5 publication Critical patent/JP2018529690A5/ja
Application granted granted Critical
Publication of JP6635562B2 publication Critical patent/JP6635562B2/ja
Expired - Fee Related legal-status Critical Current
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JP2018515119A 2015-10-09 2015-11-27 アルキニルピリジンプロリルヒドロキシラーゼ阻害剤、及びその製造法及び医薬用途 Expired - Fee Related JP6635562B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510648342.9 2015-10-09
CN201510648342.9A CN105130888A (zh) 2015-10-09 2015-10-09 炔基吡啶类脯氨酰羟化酶抑制剂、其制备方法和医药用途
PCT/CN2015/095728 WO2017059623A1 (zh) 2015-10-09 2015-11-27 炔基吡啶类脯氨酰羟化酶抑制剂、其制备方法和医药用途

Publications (3)

Publication Number Publication Date
JP2018529690A JP2018529690A (ja) 2018-10-11
JP2018529690A5 true JP2018529690A5 (OSRAM) 2019-01-10
JP6635562B2 JP6635562B2 (ja) 2020-01-29

Family

ID=54716523

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018515119A Expired - Fee Related JP6635562B2 (ja) 2015-10-09 2015-11-27 アルキニルピリジンプロリルヒドロキシラーゼ阻害剤、及びその製造法及び医薬用途

Country Status (20)

Country Link
US (2) US10889546B2 (OSRAM)
EP (1) EP3360862B1 (OSRAM)
JP (1) JP6635562B2 (OSRAM)
KR (1) KR20180063229A (OSRAM)
CN (2) CN105130888A (OSRAM)
AU (1) AU2015411258B2 (OSRAM)
BR (1) BR112018005969A2 (OSRAM)
CA (1) CA3000040A1 (OSRAM)
DK (1) DK3360862T3 (OSRAM)
ES (1) ES2794002T3 (OSRAM)
HR (1) HRP20200907T1 (OSRAM)
HU (1) HUE049409T2 (OSRAM)
LT (1) LT3360862T (OSRAM)
MX (1) MX379007B (OSRAM)
PL (1) PL3360862T3 (OSRAM)
PT (1) PT3360862T (OSRAM)
RU (1) RU2692494C1 (OSRAM)
SI (1) SI3360862T1 (OSRAM)
UA (1) UA120407C2 (OSRAM)
WO (1) WO2017059623A1 (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105130888A (zh) * 2015-10-09 2015-12-09 中国药科大学 炔基吡啶类脯氨酰羟化酶抑制剂、其制备方法和医药用途
CN107417605A (zh) * 2017-08-02 2017-12-01 江苏艾立康药业股份有限公司 作用于脯氨酰羟化酶的吡啶衍生化合物
UA125565C2 (uk) 2017-10-25 2022-04-20 Джянгсу Хенгруй Медісін Ко., Лтд. Кристалічна форма алкінілпіридинового інгібітора пролілгідроксилази та спосіб її отримання
CN110240562B (zh) * 2018-03-08 2022-04-12 江苏恒瑞医药股份有限公司 一种脯氨酰羟化酶抑制剂的可药用盐、晶型及其制备方法
US20210206720A1 (en) * 2018-05-24 2021-07-08 Suzhou Suncadia Biopharmaceuticals Co., Ltd. Method for preparing alkynyl pyridine prolyl hydroxylase inhibitor
CN109593084B (zh) * 2019-01-23 2021-09-28 中国药科大学 脯氨酰羟化酶小分子光敏前药及其制备方法与应用
EP3936119A1 (en) * 2019-03-04 2022-01-12 Jiangsu Hengrui Medicine Co., Ltd. Pharmaceutical composition of prolyl hydroxylase inhibitor and preparation method therefor
WO2022036188A1 (en) * 2020-08-14 2022-02-17 Akebia Therapeutics, Inc. Phd inhibitor compounds, compositions, and methods of use
CN112741834A (zh) * 2021-02-07 2021-05-04 复旦大学附属中山医院 HIF-1α降解抑制剂在制备酮体水平升高的冠心病药物中的应用
CN116120340B (zh) * 2021-11-15 2023-10-31 艾立康药业股份有限公司 一种吡啶并噁嗪类化合物及其制备方法、组合物和用途
CN116514710B (zh) * 2022-01-21 2024-07-05 中国药科大学 环取代炔基吡啶甲酰甘氨酸衍生物、制备方法、药物组合物和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4410480A1 (de) * 1994-03-25 1995-09-28 Hoechst Ag Sulfonamidocarbonylpyridin-2-carbonsäureesteramide sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ATE485264T1 (de) * 2006-06-26 2010-11-15 Warner Chilcott Co Llc Prolylhydroxylase-hemmer und verfahren zu ihrer anwendung
AU2007334321B2 (en) * 2006-12-18 2012-03-08 Amgen Inc. Azaquinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
TW200845991A (en) * 2007-01-12 2008-12-01 Smithkline Beecham Corp N-substituted glycine derivatives: hydroxylase inhibitors
TW201141839A (en) * 2010-04-19 2011-12-01 Daiichi Sankyo Co Ltd Substituted 5-hydroxypyrimidine-4-carboxamide compounds
US9738604B2 (en) * 2010-09-03 2017-08-22 Duke University Ethynylbenzene derivatives
JP6099644B2 (ja) 2011-07-22 2017-03-22 ベイジン ベータ ファーマシューティカルズ カンパニー， リミテッド プロリルヒドロキシラーゼ阻害剤としての化合物の多形体、およびその使用
CN105130888A (zh) * 2015-10-09 2015-12-09 中国药科大学 炔基吡啶类脯氨酰羟化酶抑制剂、其制备方法和医药用途

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