JP2018528238A5 - - Google Patents
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- Publication number
- JP2018528238A5 JP2018528238A5 JP2018515582A JP2018515582A JP2018528238A5 JP 2018528238 A5 JP2018528238 A5 JP 2018528238A5 JP 2018515582 A JP2018515582 A JP 2018515582A JP 2018515582 A JP2018515582 A JP 2018515582A JP 2018528238 A5 JP2018528238 A5 JP 2018528238A5
- Authority
- JP
- Japan
- Prior art keywords
- therapeutic
- prophylactic agent
- agent according
- oxopropanenitrile
- diazaspiro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims 10
- 230000000069 prophylactic effect Effects 0.000 claims 9
- 230000001225 therapeutic effect Effects 0.000 claims 6
- 239000004480 active ingredient Substances 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 239000002674 ointment Substances 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- ZMMOYIXZGHJMNI-UHFFFAOYSA-N 3-oxopropanenitrile Chemical compound O=CCC#N ZMMOYIXZGHJMNI-UHFFFAOYSA-N 0.000 claims 3
- -1 7H-pyrrolo [2,3-d] pyrimidin-4-yl Chemical group 0.000 claims 1
- 208000004631 alopecia areata Diseases 0.000 claims 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 230000003449 preventive effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15186644 | 2015-09-24 | ||
| EP15186644.9 | 2015-09-24 | ||
| JP2015190849A JP2017066061A (ja) | 2015-09-29 | 2015-09-29 | 円形脱毛症治療剤 |
| JP2015190849 | 2015-09-29 | ||
| PCT/EP2016/072531 WO2017050891A1 (en) | 2015-09-24 | 2016-09-22 | Treatment of alopecia areata |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018528238A JP2018528238A (ja) | 2018-09-27 |
| JP2018528238A5 true JP2018528238A5 (enExample) | 2019-10-31 |
| JP6776345B2 JP6776345B2 (ja) | 2020-10-28 |
Family
ID=57047187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515582A Active JP6776345B2 (ja) | 2015-09-24 | 2016-09-22 | 円形脱毛症の治療 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US20180263986A1 (enExample) |
| EP (1) | EP3352734B1 (enExample) |
| JP (1) | JP6776345B2 (enExample) |
| KR (1) | KR102728341B1 (enExample) |
| CN (1) | CN108135834B (enExample) |
| AU (3) | AU2016325388A1 (enExample) |
| BR (1) | BR112018005771B1 (enExample) |
| CA (1) | CA2998972A1 (enExample) |
| CY (1) | CY1122837T1 (enExample) |
| DK (1) | DK3352734T3 (enExample) |
| ES (1) | ES2779762T3 (enExample) |
| HR (1) | HRP20200472T1 (enExample) |
| HU (1) | HUE049052T2 (enExample) |
| IL (3) | IL298520A (enExample) |
| LT (1) | LT3352734T (enExample) |
| MX (1) | MX375024B (enExample) |
| MY (1) | MY196541A (enExample) |
| PL (1) | PL3352734T3 (enExample) |
| PT (1) | PT3352734T (enExample) |
| RS (1) | RS60365B1 (enExample) |
| RU (1) | RU2754997C2 (enExample) |
| SG (1) | SG10202111361TA (enExample) |
| SI (1) | SI3352734T1 (enExample) |
| TW (1) | TWI720022B (enExample) |
| UA (1) | UA124192C2 (enExample) |
| WO (1) | WO2017050891A1 (enExample) |
| ZA (1) | ZA201801722B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI889740B (zh) * | 2019-12-27 | 2025-07-11 | 日商樂敦製藥股份有限公司 | 水性組成物 |
| WO2023029943A1 (zh) * | 2021-09-03 | 2023-03-09 | 星药科技(北京)有限公司 | 一种芳杂环化合物及其制备方法和用途 |
| JP2025514747A (ja) | 2022-04-20 | 2025-05-09 | レオ ファーマ アクティーゼルスカブ | 前頭部線維性脱毛症の治療 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI466885B (zh) * | 2009-07-31 | 2015-01-01 | Japan Tobacco Inc | 含氮螺環化合物及其醫藥用途 |
| US8637569B2 (en) * | 2009-10-22 | 2014-01-28 | Api Genesis, Llc | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compounds |
| US20140343034A1 (en) * | 2013-04-25 | 2014-11-20 | Japan Tobacco Inc. | Skin barrier function improving agent |
| WO2015060208A1 (ja) * | 2013-10-21 | 2015-04-30 | 日本たばこ産業株式会社 | 眼疾患の治療剤又は予防剤 |
-
2016
- 2016-09-22 DK DK16775134.6T patent/DK3352734T3/da active
- 2016-09-22 MX MX2018003332A patent/MX375024B/es active IP Right Grant
- 2016-09-22 RU RU2018114922A patent/RU2754997C2/ru active
- 2016-09-22 PT PT167751346T patent/PT3352734T/pt unknown
- 2016-09-22 JP JP2018515582A patent/JP6776345B2/ja active Active
- 2016-09-22 SG SG10202111361TA patent/SG10202111361TA/en unknown
- 2016-09-22 MY MYPI2018701140A patent/MY196541A/en unknown
- 2016-09-22 PL PL16775134T patent/PL3352734T3/pl unknown
- 2016-09-22 IL IL298520A patent/IL298520A/en unknown
- 2016-09-22 WO PCT/EP2016/072531 patent/WO2017050891A1/en not_active Ceased
- 2016-09-22 CN CN201680054554.7A patent/CN108135834B/zh active Active
- 2016-09-22 SI SI201630694T patent/SI3352734T1/sl unknown
- 2016-09-22 EP EP16775134.6A patent/EP3352734B1/en active Active
- 2016-09-22 LT LTEP16775134.6T patent/LT3352734T/lt unknown
- 2016-09-22 CA CA2998972A patent/CA2998972A1/en active Pending
- 2016-09-22 BR BR112018005771-1A patent/BR112018005771B1/pt active IP Right Grant
- 2016-09-22 HR HRP20200472TT patent/HRP20200472T1/hr unknown
- 2016-09-22 AU AU2016325388A patent/AU2016325388A1/en not_active Abandoned
- 2016-09-22 RS RS20200322A patent/RS60365B1/sr unknown
- 2016-09-22 IL IL312861A patent/IL312861A/en unknown
- 2016-09-22 KR KR1020187010871A patent/KR102728341B1/ko active Active
- 2016-09-22 ES ES16775134T patent/ES2779762T3/es active Active
- 2016-09-22 US US15/762,188 patent/US20180263986A1/en not_active Abandoned
- 2016-09-22 HU HUE16775134A patent/HUE049052T2/hu unknown
- 2016-09-22 UA UAA201804378A patent/UA124192C2/uk unknown
- 2016-09-23 TW TW105130927A patent/TWI720022B/zh active
-
2018
- 2018-03-06 IL IL257918A patent/IL257918A/en unknown
- 2018-03-13 ZA ZA2018/01722A patent/ZA201801722B/en unknown
-
2020
- 2020-03-20 CY CY20201100268T patent/CY1122837T1/el unknown
-
2021
- 2021-04-13 US US17/228,831 patent/US20220088020A1/en not_active Abandoned
-
2022
- 2022-04-14 AU AU2022202508A patent/AU2022202508A1/en not_active Abandoned
-
2024
- 2024-01-05 US US18/405,453 patent/US20240398809A1/en not_active Abandoned
- 2024-07-09 AU AU2024204716A patent/AU2024204716A1/en active Pending
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