CY1122837T1 - Θεραπεια της γυροειδους αλωπεκιας - Google Patents
Θεραπεια της γυροειδους αλωπεκιαςInfo
- Publication number
- CY1122837T1 CY1122837T1 CY20201100268T CY201100268T CY1122837T1 CY 1122837 T1 CY1122837 T1 CY 1122837T1 CY 20201100268 T CY20201100268 T CY 20201100268T CY 201100268 T CY201100268 T CY 201100268T CY 1122837 T1 CY1122837 T1 CY 1122837T1
- Authority
- CY
- Cyprus
- Prior art keywords
- alopecia areata
- treatment
- diazaspiro
- octan
- pyrrolo
- Prior art date
Links
- 208000004631 alopecia areata Diseases 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 1
- LOWWYYZBZNSPDT-ZBEGNZNMSA-N delgocitinib Chemical compound C[C@H]1CN(C(=O)CC#N)[C@@]11CN(C=2C=3C=CNC=3N=CN=2)CC1 LOWWYYZBZNSPDT-ZBEGNZNMSA-N 0.000 abstract 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15186644 | 2015-09-24 | ||
| JP2015190849A JP2017066061A (ja) | 2015-09-29 | 2015-09-29 | 円形脱毛症治療剤 |
| PCT/EP2016/072531 WO2017050891A1 (en) | 2015-09-24 | 2016-09-22 | Treatment of alopecia areata |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1122837T1 true CY1122837T1 (el) | 2021-05-05 |
Family
ID=57047187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20201100268T CY1122837T1 (el) | 2015-09-24 | 2020-03-20 | Θεραπεια της γυροειδους αλωπεκιας |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US20180263986A1 (enExample) |
| EP (1) | EP3352734B1 (enExample) |
| JP (1) | JP6776345B2 (enExample) |
| KR (1) | KR102728341B1 (enExample) |
| CN (1) | CN108135834B (enExample) |
| AU (3) | AU2016325388A1 (enExample) |
| BR (1) | BR112018005771B1 (enExample) |
| CA (1) | CA2998972A1 (enExample) |
| CY (1) | CY1122837T1 (enExample) |
| DK (1) | DK3352734T3 (enExample) |
| ES (1) | ES2779762T3 (enExample) |
| HR (1) | HRP20200472T1 (enExample) |
| HU (1) | HUE049052T2 (enExample) |
| IL (3) | IL312861A (enExample) |
| LT (1) | LT3352734T (enExample) |
| MX (1) | MX375024B (enExample) |
| MY (1) | MY196541A (enExample) |
| PL (1) | PL3352734T3 (enExample) |
| PT (1) | PT3352734T (enExample) |
| RS (1) | RS60365B1 (enExample) |
| RU (1) | RU2754997C2 (enExample) |
| SG (1) | SG10202111361TA (enExample) |
| SI (1) | SI3352734T1 (enExample) |
| TW (1) | TWI720022B (enExample) |
| UA (1) | UA124192C2 (enExample) |
| WO (1) | WO2017050891A1 (enExample) |
| ZA (1) | ZA201801722B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119367282A (zh) * | 2019-12-27 | 2025-01-28 | 乐敦制药株式会社 | 水性组合物 |
| WO2023029943A1 (zh) * | 2021-09-03 | 2023-03-09 | 星药科技(北京)有限公司 | 一种芳杂环化合物及其制备方法和用途 |
| JP2025514747A (ja) | 2022-04-20 | 2025-05-09 | レオ ファーマ アクティーゼルスカブ | 前頭部線維性脱毛症の治療 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI466885B (zh) * | 2009-07-31 | 2015-01-01 | Japan Tobacco Inc | 含氮螺環化合物及其醫藥用途 |
| US8637569B2 (en) * | 2009-10-22 | 2014-01-28 | Api Genesis, Llc | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compounds |
| US20140343034A1 (en) * | 2013-04-25 | 2014-11-20 | Japan Tobacco Inc. | Skin barrier function improving agent |
| WO2015060208A1 (ja) * | 2013-10-21 | 2015-04-30 | 日本たばこ産業株式会社 | 眼疾患の治療剤又は予防剤 |
-
2016
- 2016-09-22 CN CN201680054554.7A patent/CN108135834B/zh active Active
- 2016-09-22 CA CA2998972A patent/CA2998972A1/en active Pending
- 2016-09-22 SI SI201630694T patent/SI3352734T1/sl unknown
- 2016-09-22 LT LTEP16775134.6T patent/LT3352734T/lt unknown
- 2016-09-22 BR BR112018005771-1A patent/BR112018005771B1/pt active IP Right Grant
- 2016-09-22 DK DK16775134.6T patent/DK3352734T3/da active
- 2016-09-22 PL PL16775134T patent/PL3352734T3/pl unknown
- 2016-09-22 RS RS20200322A patent/RS60365B1/sr unknown
- 2016-09-22 AU AU2016325388A patent/AU2016325388A1/en not_active Abandoned
- 2016-09-22 WO PCT/EP2016/072531 patent/WO2017050891A1/en not_active Ceased
- 2016-09-22 HU HUE16775134A patent/HUE049052T2/hu unknown
- 2016-09-22 MX MX2018003332A patent/MX375024B/es active IP Right Grant
- 2016-09-22 US US15/762,188 patent/US20180263986A1/en not_active Abandoned
- 2016-09-22 RU RU2018114922A patent/RU2754997C2/ru active
- 2016-09-22 MY MYPI2018701140A patent/MY196541A/en unknown
- 2016-09-22 ES ES16775134T patent/ES2779762T3/es active Active
- 2016-09-22 EP EP16775134.6A patent/EP3352734B1/en active Active
- 2016-09-22 HR HRP20200472TT patent/HRP20200472T1/hr unknown
- 2016-09-22 UA UAA201804378A patent/UA124192C2/uk unknown
- 2016-09-22 IL IL312861A patent/IL312861A/en unknown
- 2016-09-22 JP JP2018515582A patent/JP6776345B2/ja active Active
- 2016-09-22 IL IL298520A patent/IL298520A/en unknown
- 2016-09-22 PT PT167751346T patent/PT3352734T/pt unknown
- 2016-09-22 KR KR1020187010871A patent/KR102728341B1/ko active Active
- 2016-09-22 SG SG10202111361TA patent/SG10202111361TA/en unknown
- 2016-09-23 TW TW105130927A patent/TWI720022B/zh active
-
2018
- 2018-03-06 IL IL257918A patent/IL257918A/en unknown
- 2018-03-13 ZA ZA2018/01722A patent/ZA201801722B/en unknown
-
2020
- 2020-03-20 CY CY20201100268T patent/CY1122837T1/el unknown
-
2021
- 2021-04-13 US US17/228,831 patent/US20220088020A1/en not_active Abandoned
-
2022
- 2022-04-14 AU AU2022202508A patent/AU2022202508A1/en not_active Abandoned
-
2024
- 2024-01-05 US US18/405,453 patent/US20240398809A1/en not_active Abandoned
- 2024-07-09 AU AU2024204716A patent/AU2024204716B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NI201800128A (es) | Derivados de carbonucleósidos sustituidos útiles como agentes antineoplásicos | |
| MX2018003432A (es) | Compuestos heterociclicos y usos de los mismos. | |
| PH12018502102A1 (en) | Pyrrolotriazine compounds as tam inhibitors | |
| NI201700095A (es) | Derivados de nucleósidos sustituidos útiles como agentes antineoplásicos | |
| NZ721617A (en) | Heterocyclic compounds | |
| CY1126388T1 (el) | Χρηση delgocitinib για την θεραπεια χρονιουεκζεματος χεριων | |
| MX372997B (es) | Compuestos de aminopirimidina como inhibidores de jak. | |
| MX375970B (es) | Compuestos de triazolopirimidina y usos de los mismos. | |
| CU20170162A7 (es) | Derivados de fenil-tieno(2,3-d)pirimidina-hidroxiácido útiles en el tratamiento del cáncer y enfermedades autoinmunes, método de preparación de los mismos y composiciones farmacéuticas que los contienen | |
| CL2016001895A1 (es) | Compuestos | |
| EA201692003A1 (ru) | Макроциклические производные пиримидина | |
| ECSP18024565A (es) | Benzamidas sustituidas con isoxazolinas y análalogos como insecticidas | |
| EA201792374A1 (ru) | Азабензимидазолы и их применение в качестве модуляторов рецептора ampa | |
| EA201692000A1 (ru) | Макроциклические производные пиридина | |
| CU24608B1 (es) | Compuestos de dihidrooxadiazinonas sustituidas útiles en el tratamiento de enfermedades hiperproliferativas y métodos para preparar dichos compuestos | |
| MX374555B (es) | Derivados de pirimidina como inhibidores de tirosina cinasa de bruton (btk) y usos de los mismos. | |
| UY35625A (es) | Compuestos de tetrahidrocarbazol y carbazol carboxamida sustituidos como inhibidores de quinasa | |
| MX2018004664A (es) | Antagonistas de ep4. | |
| CY1122077T1 (el) | Νεα δακτυλιωμενα φαινοξυακεταμιδια | |
| CY1117881T1 (el) | Στερεες φαρμακευτικες συνθεσεις που περιλαμβανουν παραγωγα βιοπτερινης και χρησεις αυτων των συνθεσεων | |
| MX2018004868A (es) | Derivados de la pirrolidina. | |
| ZA201801722B (en) | Treatment of alopecia areata | |
| CY1123185T1 (el) | Παραγωγα ινδολιου | |
| EA201990046A1 (ru) | Производные бициклического пиридина, пиразина и пиримидина в качестве ингибиторов pi3k бета | |
| TR201910896T4 (tr) | Özgün 6,7-dihidro-3H-oksazolo[3,4-A]pirazin-5,8-dion türevi bileşikler. |