KR102728341B1 - 원형탈모증의 치료 - Google Patents
원형탈모증의 치료 Download PDFInfo
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- KR102728341B1 KR102728341B1 KR1020187010871A KR20187010871A KR102728341B1 KR 102728341 B1 KR102728341 B1 KR 102728341B1 KR 1020187010871 A KR1020187010871 A KR 1020187010871A KR 20187010871 A KR20187010871 A KR 20187010871A KR 102728341 B1 KR102728341 B1 KR 102728341B1
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- oxopropanenitrile
- diazaspiro
- pyrrolo
- pyrimidin
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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| EP15186644 | 2015-09-24 | ||
| EP15186644.9 | 2015-09-24 | ||
| JPJP-P-2015-190849 | 2015-09-29 | ||
| JP2015190849A JP2017066061A (ja) | 2015-09-29 | 2015-09-29 | 円形脱毛症治療剤 |
| PCT/EP2016/072531 WO2017050891A1 (en) | 2015-09-24 | 2016-09-22 | Treatment of alopecia areata |
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| KR20180054767A KR20180054767A (ko) | 2018-05-24 |
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| WO2021132598A1 (ja) * | 2019-12-27 | 2021-07-01 | ロート製薬株式会社 | 水性組成物 |
| WO2023029943A1 (zh) * | 2021-09-03 | 2023-03-09 | 星药科技(北京)有限公司 | 一种芳杂环化合物及其制备方法和用途 |
| JP2025514747A (ja) * | 2022-04-20 | 2025-05-09 | レオ ファーマ アクティーゼルスカブ | 前頭部線維性脱毛症の治療 |
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| TWI466885B (zh) * | 2009-07-31 | 2015-01-01 | Japan Tobacco Inc | 含氮螺環化合物及其醫藥用途 |
| US8637569B2 (en) * | 2009-10-22 | 2014-01-28 | Api Genesis, Llc | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compounds |
| US20140343034A1 (en) * | 2013-04-25 | 2014-11-20 | Japan Tobacco Inc. | Skin barrier function improving agent |
| EP3061455B1 (en) * | 2013-10-21 | 2018-11-28 | Japan Tobacco, Inc. | Therapeutic agent for ocular disease or prophylactic agent for ocular disease |
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