JP2018527287A5 - - Google Patents
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- Publication number
- JP2018527287A5 JP2018527287A5 JP2017560611A JP2017560611A JP2018527287A5 JP 2018527287 A5 JP2018527287 A5 JP 2018527287A5 JP 2017560611 A JP2017560611 A JP 2017560611A JP 2017560611 A JP2017560611 A JP 2017560611A JP 2018527287 A5 JP2018527287 A5 JP 2018527287A5
- Authority
- JP
- Japan
- Prior art keywords
- aqueous solution
- composition
- docetaxel
- composition according
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 22
- 239000007864 aqueous solution Substances 0.000 claims 19
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 9
- 229960003668 docetaxel Drugs 0.000 claims 9
- 102000008100 Human Serum Albumin Human genes 0.000 claims 7
- 108091006905 Human Serum Albumin Proteins 0.000 claims 7
- 239000013011 aqueous formulation Substances 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 208000007766 Kaposi sarcoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562162545P | 2015-05-15 | 2015-05-15 | |
| US62/162,545 | 2015-05-15 | ||
| US201562209053P | 2015-08-24 | 2015-08-24 | |
| US62/209,053 | 2015-08-24 | ||
| US201662299209P | 2016-02-24 | 2016-02-24 | |
| US62/299,209 | 2016-02-24 | ||
| PCT/US2016/032760 WO2016187147A1 (en) | 2015-05-15 | 2016-05-16 | Docetaxel and human serum albumin complexes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018527287A JP2018527287A (ja) | 2018-09-20 |
| JP2018527287A5 true JP2018527287A5 (https=) | 2019-06-20 |
Family
ID=57320749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017560611A Pending JP2018527287A (ja) | 2015-05-15 | 2016-05-16 | ドセタキセルおよびヒト血清アルブミンの複合体 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10500285B2 (https=) |
| EP (1) | EP3294286A4 (https=) |
| JP (1) | JP2018527287A (https=) |
| CN (2) | CN112807299B (https=) |
| WO (1) | WO2016187147A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3294286A4 (en) * | 2015-05-15 | 2019-01-02 | Albuvex LLC | Docetaxel and human serum albumin complexes |
| US20210386741A1 (en) * | 2016-08-19 | 2021-12-16 | Zhuhai Beihai Biotech Co., Ltd. | Formulations of ibrutinib |
| US11419842B2 (en) | 2016-10-27 | 2022-08-23 | Zhuhai Beihai Biotech Co., Ltd. | Neutral pH compositions of Docetaxel and human serum albumin |
| US20200061020A1 (en) * | 2017-05-01 | 2020-02-27 | Zhuhai Beihai Biotech Co., Ltd. | Formulations and compositions of docetaxel |
| US20210023041A1 (en) * | 2018-04-11 | 2021-01-28 | Zhuhai Beihai Biotech Co., Ltd. | Formulations and compositions of docetaxel |
| KR20210078512A (ko) | 2018-10-17 | 2021-06-28 | 선스테이트 바이오사이언시즈, 엘엘씨 | 치료 효과 향상을 위한 단일 단백질-캡슐화된 약제 |
| ES3037830T3 (en) | 2020-02-04 | 2025-10-07 | Zhuhai Beihai Biotech Co Ltd | Formulations of docetaxel |
| WO2022093800A2 (en) * | 2020-10-27 | 2022-05-05 | Elucida Oncology, Inc. | Carrier particle-drug conjugates, self-immolative linkers, and uses thereof |
| WO2022247846A1 (zh) * | 2021-05-26 | 2022-12-01 | 石药集团中奇制药技术（石家庄）有限公司 | 多西他赛白蛋白组合物和免疫检查点抑制剂的组合及用途 |
| CN113577267B (zh) * | 2021-09-06 | 2022-04-08 | 江西北正干细胞生物科技有限公司 | Nk细胞和抗体的药物组合物及其在治疗癌症中的用途 |
| AU2022443487A1 (en) * | 2022-02-25 | 2024-09-05 | Zhuhai Beihai Biotech Co., Ltd. | Taxotere composition and method |
| CN119055767A (zh) * | 2023-05-09 | 2024-12-03 | 上海津曼特生物科技有限公司 | 包含抗her2双特异性抗体的联合治疗药物及其用途 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58216126A (ja) * | 1982-06-11 | 1983-12-15 | Ono Pharmaceut Co Ltd | 可容化製剤 |
| CN1304058C (zh) * | 1996-03-12 | 2007-03-14 | Pg－Txl有限公司 | 水溶性紫杉醇产品 |
| HUP9701554D0 (en) * | 1997-09-18 | 1997-11-28 | Human Oltoanyagtermeloe Gyogys | Pharmaceutical composition containing plazma proteins |
| CA2362338A1 (en) * | 1998-07-30 | 2000-02-10 | Human Rt. | Pharmaceutically acceptable composition comprising an aqueous solution of paclitaxel and albumin |
| US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
| JP2008523111A (ja) | 2005-10-12 | 2008-07-03 | シコール インコーポレイティド | ドセタキセルの結晶形及びそれらの調製方法 |
| EP2001874A4 (en) | 2006-03-21 | 2010-04-07 | Reddys Lab Ltd Dr | DOCETAXEL POLYMORPH AND CORRESPONDING METHODS |
| EP2094084A4 (en) | 2006-10-20 | 2010-01-13 | Scinopharm Singapore Pte Ltd | PROCESS FOR PREPARING CRYSTALLINE WATER-FREE DOCETAXEL |
| WO2008102374A1 (en) | 2007-02-20 | 2008-08-28 | Dabur Pharma Limited | Amorphous form of docetaxel |
| KR100878455B1 (ko) | 2007-04-10 | 2009-01-13 | 한미약품 주식회사 | 안정한 무수결정형 도세탁셀 및 이의 제조방법 |
| US20100197944A1 (en) | 2007-07-04 | 2010-08-05 | Dr. Reddy's Laboratories Limited | Docetaxel process and polymorphs |
| CN101357126A (zh) * | 2008-08-11 | 2009-02-04 | 张文芳 | 一种稳定的紫杉烷类白蛋白脂质载药系统及其制备方法 |
| CN101361731A (zh) * | 2008-08-11 | 2009-02-11 | 张文芳 | 白蛋白稳定的多西紫杉醇冻干制剂及其在治疗肿瘤方面的应用 |
| CN101658516B (zh) * | 2008-08-26 | 2011-10-05 | 齐鲁制药有限公司 | 紫杉醇类药物组合物及其制备方法 |
| CZ303072B6 (cs) | 2009-02-13 | 2012-03-21 | Zentiva, K.S. | Polymerní konjugáty paclitaxelu a docetaxelu s pH rízeným uvolnováním kancerostatika |
| KR101149600B1 (ko) | 2009-12-31 | 2012-05-29 | 주식회사 삼양제넥스바이오 | 고순도 무수결정형 도세탁셀 제조방법 |
| EP2531173B1 (en) * | 2010-02-03 | 2018-09-26 | Oncbiomune, L.L.C. | Taxane- and taxoid-protein compositions |
| MX2012011155A (es) | 2010-03-29 | 2012-12-05 | Abraxis Bioscience Llc | Metodos para mejorar suministros de farmacos y efectividad de agentes terapeuticos. |
| US8890233B2 (en) | 2010-07-06 | 2014-11-18 | Macronix International Co., Ltd. | 3D memory array with improved SSL and BL contact layout |
| CN101926757B (zh) * | 2010-09-01 | 2013-01-02 | 北京大学 | 一种难溶性药物的液体组合物及其制备方法 |
| KR20120096200A (ko) | 2011-02-22 | 2012-08-30 | 동아제약주식회사 | 결정형 도세탁셀 및 이의 제조방법 |
| CN102688200B (zh) * | 2012-05-09 | 2014-03-26 | 广州帝奇医药技术有限公司 | 植物类抗癌靶向纳米制剂及其制备方法 |
| WO2014121033A1 (en) | 2013-02-04 | 2014-08-07 | Fl Therapeutics Llc | Soluble complexes of drug analogs and albumin |
| EP3294286A4 (en) | 2015-05-15 | 2019-01-02 | Albuvex LLC | Docetaxel and human serum albumin complexes |
-
2016
- 2016-05-16 EP EP16797113.4A patent/EP3294286A4/en not_active Withdrawn
- 2016-05-16 US US15/574,057 patent/US10500285B2/en active Active
- 2016-05-16 CN CN202110271253.2A patent/CN112807299B/zh active Active
- 2016-05-16 WO PCT/US2016/032760 patent/WO2016187147A1/en not_active Ceased
- 2016-05-16 JP JP2017560611A patent/JP2018527287A/ja active Pending
- 2016-05-16 CN CN201680021595.6A patent/CN107683134B/zh active Active
-
2019
- 2019-10-30 US US16/669,152 patent/US10780172B2/en active Active
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