JP2018526352A5 - - Google Patents
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- Publication number
- JP2018526352A5 JP2018526352A5 JP2018506301A JP2018506301A JP2018526352A5 JP 2018526352 A5 JP2018526352 A5 JP 2018526352A5 JP 2018506301 A JP2018506301 A JP 2018506301A JP 2018506301 A JP2018506301 A JP 2018506301A JP 2018526352 A5 JP2018526352 A5 JP 2018526352A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- substituted
- optionally
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SMXLVZARNMVEKM-FJFCPSMQSA-N Cc1cc(OC2CCOCC2)cc(C)c1-c(cc1)c(CCC2CNc3ncc([C@@H](C4)[C@H]4C(O)=O)cc3)c2c1F Chemical compound Cc1cc(OC2CCOCC2)cc(C)c1-c(cc1)c(CCC2CNc3ncc([C@@H](C4)[C@H]4C(O)=O)cc3)c2c1F SMXLVZARNMVEKM-FJFCPSMQSA-N 0.000 description 1
- WUEFBSDYTXRVSZ-VJQNXJLFSA-N Cc1cc(OCC2COCC2)cc(C)c1-c(c(CC1)c2C1Nc1ncc([C@@H](C3)[C@H]3C(O)=O)cc1)ccc2F Chemical compound Cc1cc(OCC2COCC2)cc(C)c1-c(c(CC1)c2C1Nc1ncc([C@@H](C3)[C@H]3C(O)=O)cc1)ccc2F WUEFBSDYTXRVSZ-VJQNXJLFSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15180175 | 2015-08-07 | ||
| EP15180175.0 | 2015-08-07 | ||
| EP15199739.2 | 2015-12-14 | ||
| EP15199739 | 2015-12-14 | ||
| PCT/EP2016/068291 WO2017025368A1 (en) | 2015-08-07 | 2016-08-01 | Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018526352A JP2018526352A (ja) | 2018-09-13 |
| JP2018526352A5 true JP2018526352A5 (OSRAM) | 2020-11-05 |
| JP6816107B2 JP6816107B2 (ja) | 2021-01-20 |
Family
ID=56618142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018506301A Expired - Fee Related JP6816107B2 (ja) | 2015-08-07 | 2016-08-01 | インダニルアミノピリジルシクロプロパンカルボン酸、医薬組成物及びこれらの使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9617251B2 (OSRAM) |
| EP (1) | EP3331860B1 (OSRAM) |
| JP (1) | JP6816107B2 (OSRAM) |
| WO (1) | WO2017025368A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7008704B2 (ja) * | 2016-11-28 | 2022-01-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インダニルアミノピリジルシクロプロパンカルボン酸、その医薬組成物及び使用 |
| JP6968181B2 (ja) * | 2017-01-26 | 2021-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インダニルアミノピラジニルシクロプロパンカルボン酸、その医薬組成物及び使用 |
| JOP20180040A1 (ar) * | 2017-04-20 | 2019-01-30 | Gilead Sciences Inc | مثبطات pd-1/pd-l1 |
| MY196582A (en) | 2018-02-13 | 2023-04-19 | Gilead Sciences Inc | PD-1/PD-L1 Inhibitors |
| EP3755311A4 (en) * | 2018-02-22 | 2021-11-10 | ChemoCentryx, Inc. | INDANAMINE AS PD-L1 ANTAGONISTS |
| CA3093851A1 (en) | 2018-03-29 | 2019-10-03 | Arbutus Biopharma Corporation | Substituted 1,1'-biphenyl compounds, analogues thereof, and methods using same |
| WO2019204609A1 (en) | 2018-04-19 | 2019-10-24 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| PT3820572T (pt) | 2018-07-13 | 2023-11-10 | Gilead Sciences Inc | Inibidores pd-1/pd-l1 |
| KR102291885B1 (ko) * | 2018-10-10 | 2021-08-23 | 한국생명공학연구원 | 카벤 화합물, 카벤-금속나노입자 복합체 및 이의 제조방법 |
| EP3870566A1 (en) | 2018-10-24 | 2021-09-01 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| KR20220150270A (ko) | 2019-10-07 | 2022-11-10 | 칼리오페, 인크. | Gpr119 효능제 |
| JP7745559B2 (ja) | 2020-02-28 | 2025-09-29 | キャリーオペ，インク． | Ｇｐｒ４０アゴニスト |
| BR112022023359A2 (pt) | 2020-05-19 | 2023-04-18 | Kallyope Inc | Ativadores de ampk |
| JP2023531726A (ja) | 2020-06-26 | 2023-07-25 | キャリーオペ，インク． | Ａｍｐｋアクチベーター |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2505322A1 (en) * | 2002-11-08 | 2004-05-21 | Takeda Pharmaceutical Company Limited | Receptor function regulator |
| JP4875978B2 (ja) * | 2004-03-15 | 2012-02-15 | 武田薬品工業株式会社 | アミノフェニルプロパン酸誘導体 |
| EP1924546A1 (en) | 2005-09-14 | 2008-05-28 | Amgen, Inc | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| US8633182B2 (en) * | 2012-05-30 | 2014-01-21 | Boehringer Ingelheim International Gmbh | Indanyloxyphenylcyclopropanecarboxylic acids |
| EP3036237A4 (en) | 2013-08-23 | 2017-01-25 | Fujian Haixi Pharmaceuticals Co. Ltd | Carboxylic acid compounds in treatment of diabetes mellitus |
-
2016
- 2016-08-01 JP JP2018506301A patent/JP6816107B2/ja not_active Expired - Fee Related
- 2016-08-01 US US15/225,038 patent/US9617251B2/en active Active
- 2016-08-01 EP EP16750134.5A patent/EP3331860B1/en active Active
- 2016-08-01 WO PCT/EP2016/068291 patent/WO2017025368A1/en not_active Ceased