|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US5333675C1
(en)
|
1986-02-25 |
2001-05-01 |
Perkin Elmer Corp |
Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
|
|
IL86724A
(en)
|
1987-06-19 |
1995-01-24 |
Siska Diagnostics Inc |
Methods and kits for amplification and testing of nucleic acid sequences
|
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
|
CA2020958C
(en)
|
1989-07-11 |
2005-01-11 |
Daniel L. Kacian |
Nucleic acid sequence amplification methods
|
|
CA2036946C
(en)
|
1990-04-06 |
2001-10-16 |
Kenneth V. Deugau |
Indexing linkers
|
|
US5223414A
(en)
|
1990-05-07 |
1993-06-29 |
Sri International |
Process for nucleic acid hybridization and amplification
|
|
US5670316A
(en)
|
1990-05-07 |
1997-09-23 |
Daikin Industries, Ltd. |
Diagnostic applications of double D-loop formation
|
|
US5273881A
(en)
|
1990-05-07 |
1993-12-28 |
Daikin Industries, Ltd. |
Diagnostic applications of double D-loop formation
|
|
US5194370A
(en)
|
1990-05-16 |
1993-03-16 |
Life Technologies, Inc. |
Promoter ligation activated transcription amplification of nucleic acid sequences
|
|
US6261808B1
(en)
|
1992-08-04 |
2001-07-17 |
Replicon, Inc. |
Amplification of nucleic acid molecules via circular replicons
|
|
US5846719A
(en)
|
1994-10-13 |
1998-12-08 |
Lynx Therapeutics, Inc. |
Oligonucleotide tags for sorting and identification
|
|
US5695934A
(en)
|
1994-10-13 |
1997-12-09 |
Lynx Therapeutics, Inc. |
Massively parallel sequencing of sorted polynucleotides
|
|
US5604097A
(en)
|
1994-10-13 |
1997-02-18 |
Spectragen, Inc. |
Methods for sorting polynucleotides using oligonucleotide tags
|
|
US5882856A
(en)
|
1995-06-07 |
1999-03-16 |
Genzyme Corporation |
Universal primer sequence for multiplex DNA amplification
|
|
US6444806B1
(en)
|
1996-04-30 |
2002-09-03 |
Hisamitsu Pharmaceutical Co., Inc. |
Conjugates and methods of forming conjugates of oligonucleotides and carbohydrates
|
|
JP2002503954A
(ja)
|
1997-04-01 |
2002-02-05 |
グラクソ、グループ、リミテッド |
核酸増幅法
|
|
JP4298912B2
(ja)
|
1997-07-07 |
2009-07-22 |
メディカル リサーチ カウンシル |
invitro選別法
|
|
FI103809B1
(fi)
|
1997-07-14 |
1999-09-30 |
Finnzymes Oy |
In vitro -menetelmä templaattien tuottamiseksi DNA-sekventointia varten
|
|
US6607878B2
(en)
|
1997-10-06 |
2003-08-19 |
Stratagene |
Collections of uniquely tagged molecules
|
|
EP1114184A2
(en)
|
1998-09-15 |
2001-07-11 |
Yale University |
Molecular cloning using rolling circle amplification
|
|
US6287825B1
(en)
|
1998-09-18 |
2001-09-11 |
Molecular Staging Inc. |
Methods for reducing the complexity of DNA sequences
|
|
US6480791B1
(en)
|
1998-10-28 |
2002-11-12 |
Michael P. Strathmann |
Parallel methods for genomic analysis
|
|
US6830884B1
(en)
|
1998-12-15 |
2004-12-14 |
Molecular Staging Inc. |
Method of amplification
|
|
US6521428B1
(en)
|
1999-04-21 |
2003-02-18 |
Genome Technologies, Llc |
Shot-gun sequencing and amplification without cloning
|
|
US7244559B2
(en)
|
1999-09-16 |
2007-07-17 |
454 Life Sciences Corporation |
Method of sequencing a nucleic acid
|
|
US7211390B2
(en)
|
1999-09-16 |
2007-05-01 |
454 Life Sciences Corporation |
Method of sequencing a nucleic acid
|
|
EP1990428B1
(en)
|
2000-02-07 |
2010-12-22 |
Illumina, Inc. |
Nucleic acid detection methods using universal priming
|
|
JP2004510433A
(ja)
|
2000-10-06 |
2004-04-08 |
ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク |
Dnaおよびrnaを解読するための大量並行方法
|
|
AR031640A1
(es)
|
2000-12-08 |
2003-09-24 |
Applied Research Systems |
Amplificacion isotermica de acidos nucleicos en un soporte solido
|
|
GB2378245A
(en)
|
2001-08-03 |
2003-02-05 |
Mats Nilsson |
Nucleic acid amplification method
|
|
GB0127564D0
(en)
|
2001-11-16 |
2002-01-09 |
Medical Res Council |
Emulsion compositions
|
|
GB0129012D0
(en)
|
2001-12-04 |
2002-01-23 |
Solexa Ltd |
Labelled nucleotides
|
|
US7057026B2
(en)
|
2001-12-04 |
2006-06-06 |
Solexa Limited |
Labelled nucleotides
|
|
AU2002222737A1
(en)
|
2001-12-08 |
2003-06-23 |
Seegene, Inc |
Annealing control primer system for regulating primer annealing specificity and its applications
|
|
US20030175749A1
(en)
|
2001-12-08 |
2003-09-18 |
Jong-Yoon Chun |
Annealing control primer and its uses
|
|
EP1319718A1
(en)
|
2001-12-14 |
2003-06-18 |
Keygene N.V. |
High throughput analysis and detection of multiple target sequences
|
|
US7399590B2
(en)
|
2002-02-21 |
2008-07-15 |
Asm Scientific, Inc. |
Recombinase polymerase amplification
|
|
US8030000B2
(en)
|
2002-02-21 |
2011-10-04 |
Alere San Diego, Inc. |
Recombinase polymerase amplification
|
|
DE60322044D1
(de)
|
2002-02-21 |
2008-08-21 |
Asm Scient Inc |
Rekombinase-polymerase-amplifikation
|
|
GB0208768D0
(en)
|
2002-04-17 |
2002-05-29 |
Univ Newcastle |
DNA polymerases
|
|
EP3002289B1
(en)
|
2002-08-23 |
2018-02-28 |
Illumina Cambridge Limited |
Modified nucleotides for polynucleotide sequencing
|
|
US7414116B2
(en)
|
2002-08-23 |
2008-08-19 |
Illumina Cambridge Limited |
Labelled nucleotides
|
|
US20040038331A1
(en)
|
2002-08-23 |
2004-02-26 |
Reddy M. Parameswara |
Solid phase synthesis of biomolecule conjugates
|
|
WO2005003375A2
(en)
|
2003-01-29 |
2005-01-13 |
454 Corporation |
Methods of amplifying and sequencing nucleic acids
|
|
JP2007524410A
(ja)
|
2004-01-23 |
2007-08-30 |
リングヴィテ エーエス |
ポリヌクレオチドライゲーション反応の改良
|
|
WO2006084132A2
(en)
|
2005-02-01 |
2006-08-10 |
Agencourt Bioscience Corp. |
Reagents, methods, and libraries for bead-based squencing
|
|
US7393665B2
(en)
|
2005-02-10 |
2008-07-01 |
Population Genetics Technologies Ltd |
Methods and compositions for tagging and identifying polynucleotides
|
|
DK1885880T3
(da)
|
2005-04-29 |
2010-11-08 |
Synthetic Genomics Inc |
Amplifikation og kloning af enkelte DNA-molekyler ved anvendelse af rolling circle-amplifikation
|
|
US20060263789A1
(en)
|
2005-05-19 |
2006-11-23 |
Robert Kincaid |
Unique identifiers for indicating properties associated with entities to which they are attached, and methods for using
|
|
ES2393318T3
(es)
|
2005-06-23 |
2012-12-20 |
Keygene N.V. |
Estrategias para la identificación y detección de alto rendimiento de polimorfismos
|
|
US20070020640A1
(en)
|
2005-07-21 |
2007-01-25 |
Mccloskey Megan L |
Molecular encoding of nucleic acid templates for PCR and other forms of sequence analysis
|
|
JP5027126B2
(ja)
|
2005-07-25 |
2012-09-19 |
アリーア サン ディエゴ, インコーポレイテッド |
リコンビナーゼポリメラーゼ増幅を多重化するための方法
|
|
WO2007018601A1
(en)
|
2005-08-02 |
2007-02-15 |
Rubicon Genomics, Inc. |
Compositions and methods for processing and amplification of dna, including using multiple enzymes in a single reaction
|
|
GB0517097D0
(en)
|
2005-08-19 |
2005-09-28 |
Solexa Ltd |
Modified nucleosides and nucleotides and uses thereof
|
|
US7405281B2
(en)
|
2005-09-29 |
2008-07-29 |
Pacific Biosciences Of California, Inc. |
Fluorescent nucleotide analogs and uses therefor
|
|
US20090170713A1
(en)
|
2005-09-29 |
2009-07-02 |
Keygene N.V. |
High throughput screening of mutagenized populations
|
|
GB0522310D0
(en)
|
2005-11-01 |
2005-12-07 |
Solexa Ltd |
Methods of preparing libraries of template polynucleotides
|
|
WO2007087312A2
(en)
|
2006-01-23 |
2007-08-02 |
Population Genetics Technologies Ltd. |
Molecular counting
|
|
US20070231823A1
(en)
|
2006-03-23 |
2007-10-04 |
Mckernan Kevin J |
Directed enrichment of genomic DNA for high-throughput sequencing
|
|
US8071308B2
(en)
|
2006-05-04 |
2011-12-06 |
Alere San Diego, Inc. |
Recombinase polymerase amplification
|
|
WO2008039674A2
(en)
|
2006-09-20 |
2008-04-03 |
Luminescent Technologies, Inc. |
Photo-mask and wafer image reconstruction
|
|
US8399188B2
(en)
|
2006-09-28 |
2013-03-19 |
Illumina, Inc. |
Compositions and methods for nucleotide sequencing
|
|
WO2008069973A2
(en)
|
2006-12-01 |
2008-06-12 |
The Trustees Of Columbia University In The City Of New York |
Four-color dna sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
|
|
US7948015B2
(en)
|
2006-12-14 |
2011-05-24 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
US8349167B2
(en)
|
2006-12-14 |
2013-01-08 |
Life Technologies Corporation |
Methods and apparatus for detecting molecular interactions using FET arrays
|
|
US8262900B2
(en)
|
2006-12-14 |
2012-09-11 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
US7932034B2
(en)
|
2006-12-20 |
2011-04-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Heat and pH measurement for sequencing of DNA
|
|
WO2008093098A2
(en)
|
2007-02-02 |
2008-08-07 |
Illumina Cambridge Limited |
Methods for indexing samples and sequencing multiple nucleotide templates
|
|
WO2008127789A2
(en)
|
2007-02-27 |
2008-10-23 |
Northwestern University |
Molecule attachment to nanoparticles
|
|
CA2700838A1
(en)
|
2007-09-28 |
2009-04-09 |
Pacific Biosciences Of California, Inc. |
Error-free amplification of dna for clonal sequencing
|
|
MX2010010600A
(es)
|
2008-03-28 |
2011-03-30 |
Pacific Biosciences California Inc |
Composiciones y metodos para secuenciacion de acidos nucleicos.
|
|
US8271206B2
(en)
*
|
2008-04-21 |
2012-09-18 |
Softgenetics Llc |
DNA sequence assembly methods of short reads
|
|
WO2009133466A2
(en)
|
2008-04-30 |
2009-11-05 |
Population Genetics Technologies Ltd. |
Asymmetric adapter library construction
|
|
GB2461127B
(en)
|
2008-06-25 |
2010-07-14 |
Ion Torrent Systems Inc |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
US8383345B2
(en)
|
2008-09-12 |
2013-02-26 |
University Of Washington |
Sequence tag directed subassembly of short sequencing reads into long sequencing reads
|
|
US8546128B2
(en)
|
2008-10-22 |
2013-10-01 |
Life Technologies Corporation |
Fluidics system for sequential delivery of reagents
|
|
US20100301398A1
(en)
|
2009-05-29 |
2010-12-02 |
Ion Torrent Systems Incorporated |
Methods and apparatus for measuring analytes
|
|
US20100137143A1
(en)
|
2008-10-22 |
2010-06-03 |
Ion Torrent Systems Incorporated |
Methods and apparatus for measuring analytes
|
|
US9080211B2
(en)
|
2008-10-24 |
2015-07-14 |
Epicentre Technologies Corporation |
Transposon end compositions and methods for modifying nucleic acids
|
|
US9394567B2
(en)
*
|
2008-11-07 |
2016-07-19 |
Adaptive Biotechnologies Corporation |
Detection and quantification of sample contamination in immune repertoire analysis
|
|
WO2010059763A1
(en)
|
2008-11-19 |
2010-05-27 |
Amyris Biotechnologies, Inc. |
Compositions and methods for the assembly of polynucleotides
|
|
WO2010127186A1
(en)
|
2009-04-30 |
2010-11-04 |
Prognosys Biosciences, Inc. |
Nucleic acid constructs and methods of use
|
|
US9309557B2
(en)
|
2010-12-17 |
2016-04-12 |
Life Technologies Corporation |
Nucleic acid amplification
|
|
US9334531B2
(en)
|
2010-12-17 |
2016-05-10 |
Life Technologies Corporation |
Nucleic acid amplification
|
|
US9309566B2
(en)
|
2010-12-17 |
2016-04-12 |
Life Technologies Corporation |
Methods, compositions, systems, apparatuses and kits for nucleic acid amplification
|
|
US8673627B2
(en)
|
2009-05-29 |
2014-03-18 |
Life Technologies Corporation |
Apparatus and methods for performing electrochemical reactions
|
|
US8776573B2
(en)
|
2009-05-29 |
2014-07-15 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes
|
|
ES3022638T3
(en)
|
2009-06-05 |
2025-05-28 |
Abbott Diagnostics Scarborough Inc |
Recombinase polymerase amplification reagents
|
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
US9315857B2
(en)
|
2009-12-15 |
2016-04-19 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse label-tags
|
|
US9677118B2
(en)
|
2014-04-21 |
2017-06-13 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
EP2606343A4
(en)
|
2010-08-18 |
2017-08-16 |
Life Technologies Corporation |
Chemical coating of microwell for electrochemical detection device
|
|
CA2811185C
(en)
|
2010-09-21 |
2020-09-22 |
Population Genetics Technologies Ltd. |
Increasing confidence of allele calls with molecular counting
|
|
EP2633470B1
(en)
|
2010-10-27 |
2016-10-26 |
Life Technologies Corporation |
Predictive model for use in sequencing-by-synthesis
|
|
EP3564392B1
(en)
|
2010-12-17 |
2021-11-24 |
Life Technologies Corporation |
Methods for nucleic acid amplification
|
|
US20130060482A1
(en)
|
2010-12-30 |
2013-03-07 |
Life Technologies Corporation |
Methods, systems, and computer readable media for making base calls in nucleic acid sequencing
|
|
KR20190002733A
(ko)
|
2010-12-30 |
2019-01-08 |
파운데이션 메디신 인코포레이티드 |
종양 샘플의 다유전자 분석의 최적화
|
|
US20130090860A1
(en)
|
2010-12-30 |
2013-04-11 |
Life Technologies Corporation |
Methods, systems, and computer readable media for making base calls in nucleic acid sequencing
|
|
EP3037536B1
(en)
|
2011-01-28 |
2019-11-27 |
Illumina, Inc. |
Oligonucleotide replacement for di-tagged and directional libraries
|
|
US9260753B2
(en)
|
2011-03-24 |
2016-02-16 |
President And Fellows Of Harvard College |
Single cell nucleic acid detection and analysis
|
|
BR112013025758B1
(pt)
|
2011-04-07 |
2021-04-06 |
Abbott Diagnostics Scarborough, Inc. |
Monitoramento de misturas de amplificação de recombinase polimerase
|
|
WO2012138926A1
(en)
|
2011-04-08 |
2012-10-11 |
Life Technologies Corporation |
Methods and kits for breaking emulsions
|
|
ES2625288T3
(es)
*
|
2011-04-15 |
2017-07-19 |
The Johns Hopkins University |
Sistema de secuenciación segura
|
|
US9809904B2
(en)
*
|
2011-04-21 |
2017-11-07 |
University Of Washington Through Its Center For Commercialization |
Methods for retrieval of sequence-verified DNA constructs
|
|
WO2012166647A1
(en)
|
2011-05-27 |
2012-12-06 |
Life Technologies Corporation |
Methods for manipulating biomolecules
|
|
US20130017978A1
(en)
|
2011-07-11 |
2013-01-17 |
Finnzymes Oy |
Methods and transposon nucleic acids for generating a dna library
|
|
US9145623B2
(en)
|
2011-07-20 |
2015-09-29 |
Thermo Fisher Scientific Oy |
Transposon nucleic acids comprising a calibration sequence for DNA sequencing
|
|
US10941396B2
(en)
*
|
2012-02-27 |
2021-03-09 |
Becton, Dickinson And Company |
Compositions and kits for molecular counting
|
|
EP2820174B1
(en)
*
|
2012-02-27 |
2019-12-25 |
The University of North Carolina at Chapel Hill |
Methods and uses for molecular tags
|
|
US9862995B2
(en)
*
|
2012-03-13 |
2018-01-09 |
Abhijit Ajit Patel |
Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
|
|
EP3744857A1
(en)
*
|
2012-03-20 |
2020-12-02 |
University Of Washington Through Its Center For Commercialization |
Methods of lowering the error rate of massively parallel dna sequencing using duplex consensus sequencing
|
|
AU2013267609C1
(en)
|
2012-05-31 |
2019-01-03 |
Board Of Regents, The University Of Texas System |
Method for accurate sequencing of DNA
|
|
WO2013188840A1
(en)
|
2012-06-14 |
2013-12-19 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for sensitive mutation detection in nucleic acid molecules
|
|
US8895249B2
(en)
|
2012-06-15 |
2014-11-25 |
Illumina, Inc. |
Kinetic exclusion amplification of nucleic acid libraries
|
|
WO2014026031A1
(en)
|
2012-08-10 |
2014-02-13 |
Sequenta, Inc. |
High sensitivity mutation detection using sequence tags
|
|
US20140066317A1
(en)
*
|
2012-09-04 |
2014-03-06 |
Guardant Health, Inc. |
Systems and methods to detect rare mutations and copy number variation
|
|
US20160040229A1
(en)
|
2013-08-16 |
2016-02-11 |
Guardant Health, Inc. |
Systems and methods to detect rare mutations and copy number variation
|
|
GB2533006B
(en)
|
2012-09-04 |
2017-06-07 |
Guardant Health Inc |
Systems and methods to detect copy number variation
|
|
CN103045726B
(zh)
*
|
2012-11-20 |
2015-11-25 |
南方科技大学 |
对多个混合dna或rna序列进行基因测序的方法及装置
|
|
EP4293125A3
(en)
|
2012-12-10 |
2024-02-28 |
Resolution Bioscience, Inc. |
Methods for targeted genomic analysis
|
|
CN105339507A
(zh)
*
|
2013-02-21 |
2016-02-17 |
托马生物科学公司 |
用于核酸分析的方法、组合物和试剂盒
|
|
US20140255929A1
(en)
|
2013-03-11 |
2014-09-11 |
Sequenta, Inc. |
Mosaic tags for labeling templates in large-scale amplifications
|
|
CN116622812A
(zh)
|
2013-03-14 |
2023-08-22 |
生命技术公司 |
基质阵列和其制备方法
|
|
ITMI20130496A1
(it)
|
2013-03-29 |
2014-09-30 |
Atlas Copco Blm Srl |
Gruppo e disposizione di montaggio di una spina di un connettore circolare a baionetta su un pannello o una parete, in particolare un pannello o una parete di un corpo scatolare di contenimento di un dispositivo elettrico o elettronico
|
|
US20140357499A1
(en)
*
|
2013-05-30 |
2014-12-04 |
Washington University |
METHODS OF LOW ERROR AMPLICON SEQUENCING (LEA-Seq) AND THE USE THEREOF
|
|
WO2015031559A1
(en)
|
2013-08-30 |
2015-03-05 |
Tensor Surgical, Inc |
Passive retrieving interosseous suture passing device
|
|
GB2518668B
(en)
|
2013-09-28 |
2017-07-12 |
Design Blue Ltd |
Flexible pads and shield systems
|
|
US9476853B2
(en)
|
2013-12-10 |
2016-10-25 |
Life Technologies Corporation |
System and method for forming microwells
|
|
ES2660989T3
(es)
|
2013-12-28 |
2018-03-27 |
Guardant Health, Inc. |
Métodos y sistemas para detectar variantes genéticas
|
|
HK1225758A1
(zh)
|
2014-01-16 |
2017-09-15 |
Illumina, Inc. |
固体支持物上的扩增子制备和测序
|
|
CN106103713B
(zh)
|
2014-02-03 |
2021-05-28 |
赛默飞世尔科技波罗的海封闭股份公司 |
用于经控制dna片段化的方法
|
|
JP6794350B2
(ja)
|
2014-07-02 |
2020-12-02 |
ライフ テクノロジーズ コーポレーション |
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|
|
EP3169799B1
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2014-07-15 |
2019-09-04 |
Qiagen Sciences, LLC |
Semi-random barcodes for nucleic acid analysis
|
|
JP6698708B2
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|
2015-06-09 |
2020-05-27 |
ライフ テクノロジーズ コーポレーション |
分子タグ付けのための方法、システム、組成物、キット、装置、及びコンピュータ可読媒体
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