JP2018520090A5 - - Google Patents
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- JP2018520090A5 JP2018520090A5 JP2017555688A JP2017555688A JP2018520090A5 JP 2018520090 A5 JP2018520090 A5 JP 2018520090A5 JP 2017555688 A JP2017555688 A JP 2017555688A JP 2017555688 A JP2017555688 A JP 2017555688A JP 2018520090 A5 JP2018520090 A5 JP 2018520090A5
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- JP
- Japan
- Prior art keywords
- injury
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- composition
- composition according
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000006378 damage Effects 0.000 claims description 32
- 208000027418 Wounds and injury Diseases 0.000 claims description 31
- 208000014674 injury Diseases 0.000 claims description 31
- 230000017423 tissue regeneration Effects 0.000 claims description 30
- 239000011573 trace mineral Substances 0.000 claims description 30
- 235000013619 trace mineral Nutrition 0.000 claims description 30
- 230000001939 inductive effect Effects 0.000 claims description 19
- 210000000130 stem cell Anatomy 0.000 claims description 14
- 208000037816 tissue injury Diseases 0.000 claims description 13
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 10
- 230000001771 impaired effect Effects 0.000 claims description 10
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 8
- 229910052802 copper Inorganic materials 0.000 claims description 8
- 239000010949 copper Substances 0.000 claims description 8
- 238000002347 injection Methods 0.000 claims description 8
- 239000007924 injection Substances 0.000 claims description 8
- 239000007943 implant Substances 0.000 claims description 6
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 5
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 5
- 229910052742 iron Inorganic materials 0.000 claims description 5
- 239000011669 selenium Substances 0.000 claims description 5
- 229910052711 selenium Inorganic materials 0.000 claims description 5
- 239000011701 zinc Substances 0.000 claims description 5
- 229910052725 zinc Inorganic materials 0.000 claims description 5
- 239000000411 inducer Substances 0.000 claims description 4
- 210000001519 tissue Anatomy 0.000 claims description 4
- 210000001185 bone marrow Anatomy 0.000 claims description 3
- 210000004556 brain Anatomy 0.000 claims description 3
- 210000004027 cell Anatomy 0.000 claims description 3
- 230000001684 chronic effect Effects 0.000 claims description 3
- 230000002950 deficient Effects 0.000 claims description 3
- 210000002216 heart Anatomy 0.000 claims description 3
- 210000004185 liver Anatomy 0.000 claims description 3
- 230000005012 migration Effects 0.000 claims description 3
- 238000013508 migration Methods 0.000 claims description 3
- 210000001719 neurosecretory cell Anatomy 0.000 claims description 3
- 210000002027 skeletal muscle Anatomy 0.000 claims description 3
- 230000001154 acute effect Effects 0.000 claims description 2
- 210000004204 blood vessel Anatomy 0.000 claims description 2
- 230000009172 bursting Effects 0.000 claims description 2
- 230000012010 growth Effects 0.000 claims description 2
- 239000012528 membrane Substances 0.000 claims description 2
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims description 2
- 238000002604 ultrasonography Methods 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 31
- 210000005013 brain tissue Anatomy 0.000 claims 3
- 238000002513 implantation Methods 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 1
- 230000000451 tissue damage Effects 0.000 claims 1
- 231100000827 tissue damage Toxicity 0.000 claims 1
- 238000000034 method Methods 0.000 description 42
- 230000012292 cell migration Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2015/077136 WO2016168993A1 (en) | 2015-04-22 | 2015-04-22 | Methods of tissue repair and regeneration |
| CNPCT/CN2015/077136 | 2015-04-22 | ||
| PCT/CN2016/078873 WO2016169416A1 (en) | 2015-04-22 | 2016-04-08 | Methods of tissue repair and regeneration |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020097590A Division JP2020143158A (ja) | 2015-04-22 | 2020-06-04 | 組織の修復及び再生の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018520090A JP2018520090A (ja) | 2018-07-26 |
| JP2018520090A5 true JP2018520090A5 (https=) | 2019-05-16 |
| JP6895388B2 JP6895388B2 (ja) | 2021-06-30 |
Family
ID=57142823
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017555688A Active JP6895388B2 (ja) | 2015-04-22 | 2016-04-08 | 組織の修復及び再生の方法 |
| JP2020097590A Pending JP2020143158A (ja) | 2015-04-22 | 2020-06-04 | 組織の修復及び再生の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020097590A Pending JP2020143158A (ja) | 2015-04-22 | 2020-06-04 | 組織の修復及び再生の方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US11077138B2 (https=) |
| EP (1) | EP3285782B1 (https=) |
| JP (2) | JP6895388B2 (https=) |
| KR (2) | KR20170137919A (https=) |
| CN (1) | CN107921062B (https=) |
| AU (1) | AU2016250971B2 (https=) |
| BR (1) | BR112017022355A2 (https=) |
| CA (1) | CA2982840C (https=) |
| CL (1) | CL2017002600A1 (https=) |
| CO (1) | CO2017010382A2 (https=) |
| DK (1) | DK3285782T3 (https=) |
| EA (1) | EA038598B1 (https=) |
| EC (1) | ECSP17068922A (https=) |
| ES (1) | ES2898655T3 (https=) |
| HK (1) | HK1251181A1 (https=) |
| HU (1) | HUE056650T2 (https=) |
| IL (1) | IL255116B (https=) |
| MX (1) | MX2017013122A (https=) |
| MY (1) | MY189322A (https=) |
| NZ (1) | NZ736516A (https=) |
| PE (1) | PE20180240A1 (https=) |
| SG (1) | SG11201708431QA (https=) |
| TW (1) | TWI702956B (https=) |
| UA (1) | UA124332C2 (https=) |
| WO (2) | WO2016168993A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016168993A1 (en) | 2015-04-22 | 2016-10-27 | Innolife Co., Ltd. | Methods of tissue repair and regeneration |
| WO2017049529A1 (en) | 2015-09-24 | 2017-03-30 | Innolife Co., Ltd. | A pharmaceutical composition comprising a copper chelating tetramine and the use thereof |
| CN106754662B (zh) * | 2016-11-21 | 2019-11-12 | 中国人民解放军军事医学科学院基础医学研究所 | 心肌细胞的制备方法 |
| TWI615127B (zh) * | 2017-01-17 | 2018-02-21 | 正崴精密工業股份有限公司 | 計算血壓的方法及其裝置 |
| WO2018217710A1 (en) * | 2017-05-22 | 2018-11-29 | The Regents Of The University Of California | Micro/nanobubble solutions for tissue preservation and generation thereof |
| TWI634528B (zh) * | 2017-08-29 | 2018-09-01 | 國立臺北商業大學 | 用於評估認知能力的電腦程式產品 |
| TWI635469B (zh) * | 2017-08-29 | 2018-09-11 | 國立臺北商業大學 | 用於反應力訓練的電腦程式產品 |
| KR102121417B1 (ko) * | 2018-10-08 | 2020-06-10 | 가천대학교 산학협력단 | Stat3 활성화제를 이용한 골격근세포 분화 유도용 조성물 및 이를 이용한 골격근세포 분화 유도 방법 |
| US12285182B2 (en) | 2018-10-10 | 2025-04-29 | Innova Vascular, Inc. | Devices and methods for removing an embolus |
| CN109513037B (zh) * | 2018-11-14 | 2021-09-17 | 华中科技大学同济医学院附属协和医院 | 一种负载介孔生物玻璃的小肠粘膜下层创面敷料 |
| WO2020172113A1 (en) * | 2019-02-18 | 2020-08-27 | Lankenau Institute For Medical Research | Scar reducing wound closure materials |
| CN110288581B (zh) * | 2019-06-26 | 2022-11-04 | 电子科技大学 | 一种基于保持形状凸性水平集模型的分割方法 |
| WO2020261133A1 (en) * | 2019-06-27 | 2020-12-30 | Friedrich Miescher Institute For Biomedical Research | Promoting tissue regeneration |
| CN111297895A (zh) * | 2020-02-20 | 2020-06-19 | 成都因诺生物医药科技有限公司 | 用于治疗动脉粥样硬化的组合物的制药用途 |
| WO2022140513A1 (en) * | 2020-12-22 | 2022-06-30 | Fluidx Medical Technology, Llc | In situ solidifying injectable compositions with transient contrast agents and methods of making and using thereof |
| WO2023039353A2 (en) * | 2021-09-08 | 2023-03-16 | The Board Of Trustees Of The University Of Illinois | Real-time super-resolution ultrasound microvessel imaging and velocimetry |
| CN114010163B (zh) * | 2021-12-02 | 2023-12-19 | 中国中医科学院医学实验中心 | 基于光学成像的表皮细胞迁移定位系统及方法 |
| CN114469897B (zh) * | 2022-01-12 | 2023-02-28 | 上海市胸科医院 | 靶向治疗心肌梗死的锂皂石复合递送材料及其制备与应用 |
| CN115177786A (zh) * | 2022-07-14 | 2022-10-14 | 山东大学 | 一种原位负载蒙脱土/纳米羟基磷灰石的壳聚糖复合支架材料及其制备方法 |
| KR20240164682A (ko) * | 2023-05-12 | 2024-11-20 | 국립해양생물자원관 | 다중구리 산화효소 펩타이드 및 이로부터 유래된 펩타이드를 포함하는 상처 치유 또는 피부 재생용 조성물 |
| CN117547554B (zh) * | 2024-01-12 | 2024-05-14 | 山东康根源生物集团有限公司 | 一种间充质干细胞修复制剂及其制备方法 |
| CN118879625A (zh) * | 2024-07-24 | 2024-11-01 | 南方医科大学珠江医院 | 一种硫化铜工程化干细胞外泌体的制备方法及其应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5580575A (en) | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
| JPH03297475A (ja) * | 1990-04-16 | 1991-12-27 | Ken Ishihara | 共振音波により薬物の放出を制御する方法 |
| US5558082A (en) | 1995-01-09 | 1996-09-24 | Spencer; Robert F. | Method of intubating a patient and introducer for use with such method |
| ATE248511T1 (de) | 1996-03-12 | 2003-09-15 | Univ Nebraska | Zusammensetzung zur zielortspezifischen verabreichung eines medikamentes und verfahren zur anwendung |
| US6896659B2 (en) | 1998-02-06 | 2005-05-24 | Point Biomedical Corporation | Method for ultrasound triggered drug delivery using hollow microbubbles with controlled fragility |
| GB9826658D0 (en) | 1998-12-03 | 1999-01-27 | Univ London | Tissue repair |
| ATE303138T1 (de) * | 2001-06-12 | 2005-09-15 | Vivoxid Oy | Poröses schwammartiges zellulosematerial zur behandlung von verletzungen |
| US20060100278A1 (en) * | 2002-08-20 | 2006-05-11 | Cooper Garth J S | Dosage forms and related therapies |
| CN1688301A (zh) | 2002-08-20 | 2005-10-26 | 普罗特米克斯公司 | 药物剂型及相关的治疗用途 |
| KR101528918B1 (ko) | 2004-11-07 | 2015-06-15 | 쿠프론 인코포레이티드 | 상처, 화상 및 다른 피부 질환을 치료하기 위한 구리 함유물질 |
| US20070048387A1 (en) | 2005-09-01 | 2007-03-01 | Edwards Jeffrey D | Tissue disruption treatment and composition for use thereof |
| WO2008057443A2 (en) | 2006-11-03 | 2008-05-15 | Multiple Sclerosis Research Center Of New York | Bone marrow-derived mesenchymal stem cells as a source of neural progenitors |
| US8481066B2 (en) | 2009-07-16 | 2013-07-09 | The Curators Of The University Of Missouri | Scaffold for tissue regeneration in mammals |
| US8287896B2 (en) | 2010-01-06 | 2012-10-16 | The Curators Of The University Of Missouri | Scaffolds with trace element for tissue regeneration in mammals |
| JP5721712B2 (ja) * | 2009-07-16 | 2015-05-20 | ザ・キュレーターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリＴｈｅ Ｃｕｒａｔｏｒｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍｉｓｓｏｕｒｉ | 哺乳類の組織再生用の微量元素含有スキャフォールド |
| CN102302507B (zh) * | 2010-07-12 | 2014-02-05 | 四川大学华西医院 | 定向控释微量元素的药物组合物及制备方法和应用 |
| CN101926821B (zh) | 2010-07-12 | 2012-01-25 | 四川大学华西医院 | 一种靶向释放微量元素的药物组合物及制备方法和应用 |
| CN103502218B (zh) | 2011-03-04 | 2016-08-17 | 生命科技公司 | 用于缀合生物分子的化合物和方法 |
| JP5598864B2 (ja) | 2011-12-05 | 2014-10-01 | 北海道公立大学法人 札幌医科大学 | 細胞増殖方法ならびに組織の修復および再生のための医薬 |
| CN103467578B (zh) * | 2012-06-08 | 2015-07-08 | 四川大学华西医院 | 一种短肽、载铜纳米生物材料及在制备治疗脑梗死的药物中的应用 |
| WO2014027474A1 (ja) * | 2012-08-17 | 2014-02-20 | 株式会社Ｃｌｉｏ | 心筋梗塞の修復再生を誘導する多能性幹細胞 |
| WO2014035465A1 (en) | 2012-08-28 | 2014-03-06 | Original Biomedicals Co., Ltd. | The controlled release method for a pharmaceutical composition composed of chelating complex micelles |
| US11285115B2 (en) | 2013-02-28 | 2022-03-29 | Ramot At Tel-Aviv University Ltd. | Peptide-based hydrogel particles and uses thereof |
| CN106278907B (zh) | 2014-12-17 | 2019-06-21 | 四川科瑞德凯华制药有限公司 | 一种盐酸曲恩汀化合物 |
| WO2016168993A1 (en) | 2015-04-22 | 2016-10-27 | Innolife Co., Ltd. | Methods of tissue repair and regeneration |
| WO2017049529A1 (en) | 2015-09-24 | 2017-03-30 | Innolife Co., Ltd. | A pharmaceutical composition comprising a copper chelating tetramine and the use thereof |
-
2015
- 2015-04-22 WO PCT/CN2015/077136 patent/WO2016168993A1/en not_active Ceased
-
2016
- 2016-04-08 BR BR112017022355A patent/BR112017022355A2/pt not_active Application Discontinuation
- 2016-04-08 AU AU2016250971A patent/AU2016250971B2/en active Active
- 2016-04-08 DK DK16782563.7T patent/DK3285782T3/da active
- 2016-04-08 ES ES16782563T patent/ES2898655T3/es active Active
- 2016-04-08 PE PE2017002201A patent/PE20180240A1/es unknown
- 2016-04-08 UA UAA201711249A patent/UA124332C2/uk unknown
- 2016-04-08 US US15/568,386 patent/US11077138B2/en active Active
- 2016-04-08 MX MX2017013122A patent/MX2017013122A/es unknown
- 2016-04-08 HK HK18110758.1A patent/HK1251181A1/zh unknown
- 2016-04-08 CN CN201680029765.5A patent/CN107921062B/zh active Active
- 2016-04-08 JP JP2017555688A patent/JP6895388B2/ja active Active
- 2016-04-08 CA CA2982840A patent/CA2982840C/en active Active
- 2016-04-08 MY MYPI2017703903A patent/MY189322A/en unknown
- 2016-04-08 EP EP16782563.7A patent/EP3285782B1/en active Active
- 2016-04-08 SG SG11201708431QA patent/SG11201708431QA/en unknown
- 2016-04-08 WO PCT/CN2016/078873 patent/WO2016169416A1/en not_active Ceased
- 2016-04-08 EA EA201792307A patent/EA038598B1/ru unknown
- 2016-04-08 KR KR1020177033507A patent/KR20170137919A/ko not_active Ceased
- 2016-04-08 KR KR1020197037851A patent/KR102347010B1/ko active Active
- 2016-04-08 HU HUE16782563A patent/HUE056650T2/hu unknown
- 2016-04-08 NZ NZ736516A patent/NZ736516A/en unknown
- 2016-04-21 TW TW105112419A patent/TWI702956B/zh active
-
2017
- 2017-10-11 CO CONC2017/0010382A patent/CO2017010382A2/es unknown
- 2017-10-13 CL CL2017002600A patent/CL2017002600A1/es unknown
- 2017-10-17 EC ECIEPI201768922A patent/ECSP17068922A/es unknown
- 2017-10-18 IL IL255116A patent/IL255116B/en active IP Right Grant
-
2020
- 2020-06-04 JP JP2020097590A patent/JP2020143158A/ja active Pending
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