JP2018515513A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018515513A5 JP2018515513A5 JP2017558542A JP2017558542A JP2018515513A5 JP 2018515513 A5 JP2018515513 A5 JP 2018515513A5 JP 2017558542 A JP2017558542 A JP 2017558542A JP 2017558542 A JP2017558542 A JP 2017558542A JP 2018515513 A5 JP2018515513 A5 JP 2018515513A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- antibody according
- seq
- region
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 2
- 229960003957 dexamethasone Drugs 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021078658A JP2021130668A (ja) | 2015-05-13 | 2021-05-06 | 多発性骨髄腫(mm)の処置 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15167597.2 | 2015-05-13 | ||
| EP15167597 | 2015-05-13 | ||
| PCT/EP2016/060810 WO2016180958A1 (en) | 2015-05-13 | 2016-05-13 | Treatment for multiple myeloma (mm) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021078658A Division JP2021130668A (ja) | 2015-05-13 | 2021-05-06 | 多発性骨髄腫(mm)の処置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018515513A JP2018515513A (ja) | 2018-06-14 |
| JP2018515513A5 true JP2018515513A5 (cg-RX-API-DMAC7.html) | 2019-06-13 |
| JP7160533B2 JP7160533B2 (ja) | 2022-10-25 |
Family
ID=53174925
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017558542A Active JP7160533B2 (ja) | 2015-05-13 | 2016-05-13 | 多発性骨髄腫(mm)の処置 |
| JP2021078658A Pending JP2021130668A (ja) | 2015-05-13 | 2021-05-06 | 多発性骨髄腫(mm)の処置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021078658A Pending JP2021130668A (ja) | 2015-05-13 | 2021-05-06 | 多発性骨髄腫(mm)の処置 |
Country Status (24)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20210044A1 (ar) | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| PT3294769T (pt) * | 2015-05-13 | 2021-04-13 | Morphosys Ag | Tratamento para mieloma múltiplo (mm) |
| US11613586B2 (en) | 2016-07-15 | 2023-03-28 | Takeda Pharmaceutical Company Limited | Methods and materials for assessing response to plasmablast- and plasma cell-depleting therapies |
| WO2019140410A1 (en) | 2018-01-12 | 2019-07-18 | Takeda Pharmaceutical Company Limited | Subcutaneous dosing of anti-cd38 antibodies |
| CN110144008B (zh) | 2018-02-12 | 2021-03-19 | 杭州尚健生物技术有限公司 | Cd38蛋白抗体及其应用 |
| BR112020019710A2 (pt) * | 2018-03-28 | 2021-01-26 | Takeda Pharmaceutical Company Limited | métodos para tratar uma doença em um sujeito e para tratar um câncer hematológico em um sujeito, e, forma farmacêutica unitária. |
| CN109265551B (zh) * | 2018-09-25 | 2020-09-15 | 华东师范大学 | Cd38抗体、嵌合抗原受体和药物 |
| MX2021007047A (es) * | 2018-12-14 | 2021-10-26 | Morphosys Ag | Formulaciones de anticuerpos. |
| WO2020160020A1 (en) * | 2019-01-28 | 2020-08-06 | Sanofi | Methods of treating multiple myeloma |
| US20200308296A1 (en) * | 2019-03-28 | 2020-10-01 | Janssen Biotech, Inc. | Clinically Proven Subcutaneous Pharmaceutical Compositions Comprising Anti-CD38 Antibodies and Their Uses in Combination with Pomalidomide and Dexamethasone |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020164788A1 (en) | 1994-12-02 | 2002-11-07 | The Wellcome Foundation Limited | Humanized antibodies to CD38 |
| CA2329940A1 (en) | 1998-06-05 | 1999-12-09 | Mayo Foundation For Medical Education And Research | Use of genetically engineered antibodies to cd38 to treat multiple myeloma |
| EP1174440A1 (en) | 2000-07-19 | 2002-01-23 | U-BISys B.V. | A selectively-expressed epitope on the human CD38 molecule detected by a phage display library-derived human scFv antibody fragment |
| US8263746B2 (en) | 2004-02-06 | 2012-09-11 | Morphosys Ag | Anti-CD38 human antibodies and uses thereof |
| JP2008504013A (ja) | 2004-02-06 | 2008-02-14 | モルフォシス・アクチェンゲゼルシャフト | 抗cd38ヒト抗体及びその用途 |
| NZ586780A (en) | 2005-03-23 | 2012-02-24 | Genmab As | Antibodies against CD38 for treatment of multiple myeloma |
| EP2799451A1 (en) | 2005-05-24 | 2014-11-05 | MorphoSys AG | Generation and profiling of fully human HuCAL GOLD®-derived therapeutic antibodies specific for human CD38 |
| KR20150139636A (ko) | 2005-10-12 | 2015-12-11 | 모르포시스 아게 | 인간 cd38에 특이적인 완전 인간 hucal gold-유도 치료 항체들의 생성 및 프로파일링 |
| BRPI0716647A2 (pt) * | 2006-08-07 | 2017-05-16 | Dana Farber Cancer Inst Inc | processos de tratamento de mieloma múltiplo utilizando terapias de combinação baseadas em anticorpos anti-cs1 |
| EP3753576A1 (en) * | 2006-09-26 | 2020-12-23 | Genmab A/S | Combination treatment of cd38-expressing tumors |
| EP1914242A1 (en) | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
| RS59769B1 (sr) * | 2010-06-09 | 2020-02-28 | Genmab As | Antitela protiv humanog cd38 |
| KR101912957B1 (ko) | 2010-09-27 | 2018-10-29 | 모르포시스 아게 | 다발성 골수종 및 nhl 치료를 위한 항-cd38 항체 및 레날리도마이드 또는 보르테조밉 |
| US9738933B2 (en) * | 2012-12-05 | 2017-08-22 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | RNF41 as a biomarker predicting response to lenalidomide in non-del(5q) MDS |
| CN103421115B (zh) * | 2013-09-02 | 2015-06-03 | 东南大学 | 一种cd38纳米抗体及应用 |
| EP3063173B1 (en) * | 2013-10-31 | 2020-07-29 | Sanofi | Specific anti-cd38 antibodies for treating human cancers |
| EA201692502A1 (ru) | 2014-06-16 | 2017-09-29 | Мэйо Фаундейшн Фор Медикал Эдьюкейшн Энд Рисерч | Лечение миелом |
| US10617757B2 (en) * | 2014-08-08 | 2020-04-14 | The Regents Of The University Of California | Methods for treating multiple myeloma |
| PH12017500442B1 (en) | 2014-09-09 | 2023-05-24 | Janssen Biotech Inc | Combination therapies with anti-cd38 antibodies |
| PT3294769T (pt) * | 2015-05-13 | 2021-04-13 | Morphosys Ag | Tratamento para mieloma múltiplo (mm) |
-
2016
- 2016-05-13 PT PT167233493T patent/PT3294769T/pt unknown
- 2016-05-13 HR HRP20210552TT patent/HRP20210552T1/hr unknown
- 2016-05-13 SM SM20210202T patent/SMT202100202T1/it unknown
- 2016-05-13 KR KR1020177035726A patent/KR20180008571A/ko not_active Ceased
- 2016-05-13 DK DK16723349.3T patent/DK3294769T3/da active
- 2016-05-13 CN CN201680027238.0A patent/CN107614530A/zh active Pending
- 2016-05-13 WO PCT/EP2016/060810 patent/WO2016180958A1/en not_active Ceased
- 2016-05-13 AU AU2016260895A patent/AU2016260895B2/en active Active
- 2016-05-13 ES ES16723349T patent/ES2862708T3/es active Active
- 2016-05-13 MX MX2017014396A patent/MX380557B/es unknown
- 2016-05-13 EP EP16723349.3A patent/EP3294769B1/en active Active
- 2016-05-13 US US15/569,495 patent/US10533057B2/en active Active
- 2016-05-13 CA CA2984464A patent/CA2984464C/en active Active
- 2016-05-13 SG SG11201708691VA patent/SG11201708691VA/en unknown
- 2016-05-13 RS RS20210419A patent/RS61668B1/sr unknown
- 2016-05-13 JP JP2017558542A patent/JP7160533B2/ja active Active
- 2016-05-13 RU RU2017137496A patent/RU2723047C2/ru active
- 2016-05-13 LT LTEP16723349.3T patent/LT3294769T/lt unknown
- 2016-05-13 HU HUE16723349A patent/HUE054271T2/hu unknown
- 2016-05-13 SI SI201631139T patent/SI3294769T1/sl unknown
- 2016-05-13 PL PL16723349T patent/PL3294769T3/pl unknown
-
2017
- 2017-11-09 IL IL255552A patent/IL255552B/en unknown
- 2017-12-11 ZA ZA2017/08386A patent/ZA201708386B/en unknown
-
2019
- 2019-11-25 US US16/693,904 patent/US11591406B2/en active Active
-
2021
- 2021-03-30 CY CY20211100276T patent/CY1123982T1/el unknown
- 2021-05-06 JP JP2021078658A patent/JP2021130668A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018515513A5 (cg-RX-API-DMAC7.html) | ||
| PE20200294A1 (es) | Anticuerpos que se unen especificamente a pd-1 y metodos de uso | |
| JP2015514110A5 (cg-RX-API-DMAC7.html) | ||
| JP2016520514A5 (cg-RX-API-DMAC7.html) | ||
| JP2013542194A5 (cg-RX-API-DMAC7.html) | ||
| AR110203A1 (es) | Anticuerpos anti-tim-3 para combinación con anticuerpos anti-pd-1 | |
| JP2018021031A5 (cg-RX-API-DMAC7.html) | ||
| PE20200011A1 (es) | ANTICUERPOS ANTI-PEPTIDO BETA AMILOIDE N3pGlu Y SUS USOS | |
| NZ610294A (en) | Human antibodies to human tnf-like ligand 1a (tl1a) | |
| HRP20171992T1 (hr) | Protutijela protiv cgrp | |
| PE20181090A1 (es) | Modulacion y tratamiento inmunes de tumores solidos con anticuerpos que se unen especificamente a cd38 | |
| RU2017137496A (ru) | Средство для лечения множественной миеломы (ММ) | |
| PE20212088A1 (es) | Anticuerpos anti-tau y uso de los mismos | |
| JP2015530399A5 (cg-RX-API-DMAC7.html) | ||
| PE20221337A1 (es) | Anticuerpos trem2 y usos de estos | |
| NZ729158A (en) | Anti-ctla4 monoclonal antibody or antigen binding fragment thereof, medicinal composition and use | |
| PE20161571A1 (es) | Anticuerpos anti-ox40 y metodos de uso | |
| PE20090161A1 (es) | Anticuerpos monoclonales anti cxcl13 | |
| AR103713A1 (es) | Anticuerpos contra tau y sus usos | |
| ES2687282T3 (es) | Anticuerpos humanizados ANTI-CD134 (OX40) y sus usos | |
| PE20150025A1 (es) | Anticuerpos e inmunoconjugados contra ly6e y metodos de uso | |
| CO6230999A2 (es) | Anticuerpo anti-esclerostina | |
| NZ631007A (en) | Anti-c5 antibodies having improved pharmacokinetics | |
| NZ628528A (en) | Optimization of antibodies that bind lymphocyte activation gene-3 (lag-3), and uses thereof | |
| JP2015535828A5 (cg-RX-API-DMAC7.html) |