JP2018514218A5 - - Google Patents
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- Publication number
- JP2018514218A5 JP2018514218A5 JP2017557123A JP2017557123A JP2018514218A5 JP 2018514218 A5 JP2018514218 A5 JP 2018514218A5 JP 2017557123 A JP2017557123 A JP 2017557123A JP 2017557123 A JP2017557123 A JP 2017557123A JP 2018514218 A5 JP2018514218 A5 JP 2018514218A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- biological sample
- specific
- specific nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 24
- 108020004707 nucleic acids Proteins 0.000 claims 16
- 102000039446 nucleic acids Human genes 0.000 claims 16
- 150000007523 nucleic acids Chemical class 0.000 claims 16
- 239000012472 biological sample Substances 0.000 claims 14
- 238000003752 polymerase chain reaction Methods 0.000 claims 7
- 210000001519 tissue Anatomy 0.000 claims 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 239000002299 complementary DNA Substances 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 3
- 208000035475 disorder Diseases 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 108091070501 miRNA Proteins 0.000 claims 3
- 239000002679 microRNA Substances 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 238000011529 RT qPCR Methods 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 238000007847 digital PCR Methods 0.000 claims 2
- 210000000582 semen Anatomy 0.000 claims 2
- 206010036790 Productive cough Diseases 0.000 claims 1
- 108020004688 Small Nuclear RNA Proteins 0.000 claims 1
- 102000039471 Small Nuclear RNA Human genes 0.000 claims 1
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 210000004381 amniotic fluid Anatomy 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 239000013592 cell lysate Substances 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 239000012228 culture supernatant Substances 0.000 claims 1
- 210000000416 exudates and transudate Anatomy 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 108091049679 miR-20a stem-loop Proteins 0.000 claims 1
- 108091030817 miR-20a-1 stem-loop Proteins 0.000 claims 1
- 108091086627 miR-20a-2 stem-loop Proteins 0.000 claims 1
- 108091069790 miR-20a-3 stem-loop Proteins 0.000 claims 1
- 108091062637 miR-367 stem-loop Proteins 0.000 claims 1
- 108091084261 miR-371a stem-loop Proteins 0.000 claims 1
- 108091062109 miR-372 stem-loop Proteins 0.000 claims 1
- 108091043953 miR-373 stem-loop Proteins 0.000 claims 1
- 108091032902 miR-93 stem-loop Proteins 0.000 claims 1
- 239000012188 paraffin wax Substances 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102015106646 | 2015-04-29 | ||
| DE102015106646.7 | 2015-04-29 | ||
| EP15195182 | 2015-11-18 | ||
| EP15195182.9 | 2015-11-18 | ||
| PCT/EP2016/059604 WO2016174199A1 (en) | 2015-04-29 | 2016-04-29 | Detection of nucleic acid molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018514218A JP2018514218A (ja) | 2018-06-07 |
| JP2018514218A5 true JP2018514218A5 (enExample) | 2019-05-09 |
| JP6698696B2 JP6698696B2 (ja) | 2020-05-27 |
Family
ID=55862785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017557123A Active JP6698696B2 (ja) | 2015-04-29 | 2016-04-29 | 核酸分子の検出 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10889855B2 (enExample) |
| EP (1) | EP3289095B1 (enExample) |
| JP (1) | JP6698696B2 (enExample) |
| KR (1) | KR102478976B1 (enExample) |
| CN (1) | CN107873058B (enExample) |
| AU (1) | AU2016256581B2 (enExample) |
| CA (1) | CA2982416A1 (enExample) |
| DK (1) | DK3289095T5 (enExample) |
| EA (1) | EA037535B1 (enExample) |
| ES (1) | ES2736850T3 (enExample) |
| HU (1) | HUE045865T2 (enExample) |
| IL (1) | IL255081B (enExample) |
| MX (1) | MX369054B (enExample) |
| PL (1) | PL3289095T3 (enExample) |
| PT (1) | PT3289095T (enExample) |
| SG (1) | SG11201708274VA (enExample) |
| WO (1) | WO2016174199A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7391367B2 (ja) | 2016-11-02 | 2023-12-05 | ミーアディテクト ゲーエムベーハー | 前段階の精巣胚細胞腫瘍の早期発見 |
| US12065644B2 (en) * | 2017-02-16 | 2024-08-20 | Takara Bio Usa, Inc. | Methods of preparing nucleic acid libraries and compositions and kits for practicing the same |
| CN111363840A (zh) * | 2020-03-30 | 2020-07-03 | 上海市计量测试技术研究院 | 一种检测基于RNAi转基因植物双链RNA的试剂盒及其应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101363057B (zh) * | 2008-09-09 | 2011-11-09 | 浙江理工大学 | 一种生物样本中miRNA绝对表达量的检测方法 |
-
2016
- 2016-04-29 DK DK16719856.3T patent/DK3289095T5/da active
- 2016-04-29 US US15/567,921 patent/US10889855B2/en active Active
- 2016-04-29 ES ES16719856T patent/ES2736850T3/es active Active
- 2016-04-29 EA EA201791987A patent/EA037535B1/ru not_active IP Right Cessation
- 2016-04-29 CA CA2982416A patent/CA2982416A1/en active Pending
- 2016-04-29 WO PCT/EP2016/059604 patent/WO2016174199A1/en not_active Ceased
- 2016-04-29 PT PT16719856T patent/PT3289095T/pt unknown
- 2016-04-29 JP JP2017557123A patent/JP6698696B2/ja active Active
- 2016-04-29 HU HUE16719856A patent/HUE045865T2/hu unknown
- 2016-04-29 AU AU2016256581A patent/AU2016256581B2/en active Active
- 2016-04-29 EP EP16719856.3A patent/EP3289095B1/en active Active
- 2016-04-29 MX MX2017013454A patent/MX369054B/es active IP Right Grant
- 2016-04-29 SG SG11201708274VA patent/SG11201708274VA/en unknown
- 2016-04-29 KR KR1020177032038A patent/KR102478976B1/ko active Active
- 2016-04-29 CN CN201680024364.0A patent/CN107873058B/zh active Active
- 2016-04-29 PL PL16719856T patent/PL3289095T3/pl unknown
-
2017
- 2017-10-17 IL IL255081A patent/IL255081B/en active IP Right Grant
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