JP2018513149A5 - - Google Patents

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Publication number
JP2018513149A5
JP2018513149A5 JP2017552973A JP2017552973A JP2018513149A5 JP 2018513149 A5 JP2018513149 A5 JP 2018513149A5 JP 2017552973 A JP2017552973 A JP 2017552973A JP 2017552973 A JP2017552973 A JP 2017552973A JP 2018513149 A5 JP2018513149 A5 JP 2018513149A5
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JP
Japan
Prior art keywords
seq
variable domain
chain variable
amino acid
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017552973A
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English (en)
Japanese (ja)
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JP7068825B2 (ja
JP2018513149A (ja
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Application filed filed Critical
Priority claimed from PCT/US2016/026567 external-priority patent/WO2016164669A2/en
Publication of JP2018513149A publication Critical patent/JP2018513149A/ja
Publication of JP2018513149A5 publication Critical patent/JP2018513149A5/ja
Priority to JP2021086783A priority Critical patent/JP7273101B2/ja
Application granted granted Critical
Publication of JP7068825B2 publication Critical patent/JP7068825B2/ja
Priority to JP2022101169A priority patent/JP2022118222A/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017552973A 2015-04-08 2016-04-08 Cd38に結合する抗体治療剤 Expired - Fee Related JP7068825B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021086783A JP7273101B2 (ja) 2015-04-08 2021-05-24 Cd38に結合する抗体治療剤
JP2022101169A JP2022118222A (ja) 2015-04-08 2022-06-23 Cd38に結合する抗体治療剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562144901P 2015-04-08 2015-04-08
US62/144,901 2015-04-08
PCT/US2016/026567 WO2016164669A2 (en) 2015-04-08 2016-04-08 Antibody therapeutics that bind cd38

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021086783A Division JP7273101B2 (ja) 2015-04-08 2021-05-24 Cd38に結合する抗体治療剤

Publications (3)

Publication Number Publication Date
JP2018513149A JP2018513149A (ja) 2018-05-24
JP2018513149A5 true JP2018513149A5 (https=) 2019-05-16
JP7068825B2 JP7068825B2 (ja) 2022-05-17

Family

ID=57072959

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017552973A Expired - Fee Related JP7068825B2 (ja) 2015-04-08 2016-04-08 Cd38に結合する抗体治療剤
JP2021086783A Active JP7273101B2 (ja) 2015-04-08 2021-05-24 Cd38に結合する抗体治療剤
JP2022101169A Pending JP2022118222A (ja) 2015-04-08 2022-06-23 Cd38に結合する抗体治療剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021086783A Active JP7273101B2 (ja) 2015-04-08 2021-05-24 Cd38に結合する抗体治療剤
JP2022101169A Pending JP2022118222A (ja) 2015-04-08 2022-06-23 Cd38に結合する抗体治療剤

Country Status (8)

Country Link
US (4) US10059774B2 (https=)
EP (2) EP4180058A1 (https=)
JP (3) JP7068825B2 (https=)
CN (2) CN113527495A (https=)
AR (1) AR104213A1 (https=)
ES (1) ES2927119T3 (https=)
TW (1) TW201702264A (https=)
WO (2) WO2016164669A2 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10100118B2 (en) 2015-04-08 2018-10-16 Sorrento Therapeutics, Inc. Antibody therapeutics that bind CD123
ES2927119T3 (es) 2015-04-08 2022-11-02 Sorrento Therapeutics Inc Productos terapéuticos de anticuerpos que se unen a CD38
JP2020521452A (ja) 2017-05-24 2020-07-27 パンディオン・セラピューティクス・インコーポレイテッド 標的化免疫寛容
CN118772278A (zh) 2017-06-02 2024-10-15 辉瑞公司 Flt3的特异性抗体及其用途
WO2018224682A1 (en) 2017-06-08 2018-12-13 Tusk Therapeutics Ltd Cd38 modulating antibody
KR102719065B1 (ko) 2017-06-08 2024-10-17 블랙 벨트 테라퓨틱스 리미티드 Cd38 조정 항체
KR102771835B1 (ko) 2017-06-20 2025-02-26 비바솔, 인코포레이티드. Cd38 항체 약물 접합체
US11542338B2 (en) 2017-08-16 2023-01-03 Black Belt Therapeutics Limited CD38 modulating antibody
SG11202000321PA (en) 2017-08-16 2020-02-27 Black Belt Therapeutics Ltd Cd38 modulating antibody
WO2019035938A1 (en) 2017-08-16 2019-02-21 Elstar Therapeutics, Inc. MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
AU2018316522B2 (en) * 2017-08-16 2025-02-20 Black Belt Therapeutics Limited CD38 antibody
CA3080109A1 (en) * 2017-11-03 2019-05-09 Sorrento Therapeutics, Inc. Cd38-directed chimeric antigen receptor constructs
US10174091B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
SG11202008568WA (en) * 2018-03-09 2020-10-29 Sorrento Therapeutics Inc Dimeric antigen receptors (dar)
CN112313250B (zh) * 2018-06-20 2024-10-01 索伦托药业有限公司 结合cd38的变体抗体
CA3111651A1 (en) 2018-09-11 2020-03-19 Jiangsu Hengrui Medicine Co., Ltd. Anti-cd38 antibody, antigen-binding fragment thereof, and pharmaceutical use
JP7555953B2 (ja) * 2019-03-29 2024-09-25 ソレント・セラピューティクス・インコーポレイテッド Cd38に結合する操作されたバリアント抗体
WO2020236875A1 (en) 2019-05-20 2020-11-26 Pandion Therapeutics, Inc. Madcam targeted immunotolerance
AU2020299774A1 (en) * 2019-07-03 2022-01-20 Peptidream Inc. CD38-binding agents and uses thereof
TW202124437A (zh) * 2019-08-19 2021-07-01 美商潘迪恩營運公司 以pd-1促效劑進行之標靶免疫耐受性
WO2021113596A2 (en) 2019-12-05 2021-06-10 Sorrento Therapeutics, Inc. Compositions and methods comprising an anti-cd47 antibody in combination with a tumor targeting antibody
US11981715B2 (en) 2020-02-21 2024-05-14 Pandion Operations, Inc. Tissue targeted immunotolerance with a CD39 effector
EP4107189A4 (en) * 2020-02-21 2024-07-03 Pandion Operations, Inc. TISSUE-TARGETED IMMUNOTOLERANCE WITH PD-1 AGONISTS OR IL-2 MUTEINS
WO2022015956A1 (en) 2020-07-15 2022-01-20 Sorrento Therapeutics, Inc. Improved process for dna integration using rna-guided endonucleases
BR112023003087A2 (pt) * 2020-08-19 2023-03-28 Pandion Operations Inc Anticorpos anti-pd-1 multiparatópicos e usos dos mesmos
US12181485B2 (en) * 2020-09-10 2024-12-31 CASI Pharmaceuticals, Inc Methods of blood screening

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3817827A (en) 1972-03-30 1974-06-18 Scott Paper Co Soft absorbent fibrous webs containing elastomeric bonding material and formed by creping and embossing
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
DE3675588D1 (de) 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US6010902A (en) 1988-04-04 2000-01-04 Bristol-Meyers Squibb Company Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
GB9014932D0 (en) 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
JP3051145B2 (ja) 1990-08-28 2000-06-12 住友製薬株式会社 新規なポリエチレングリコール誘導体修飾ペプチド
US5582996A (en) 1990-12-04 1996-12-10 The Wistar Institute Of Anatomy & Biology Bifunctional antibodies and method of preparing same
DE4118120A1 (de) 1991-06-03 1992-12-10 Behringwerke Ag Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
JPH05244982A (ja) 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化b−b10
ATE240394T1 (de) 1992-10-23 2003-05-15 Immunex Corp Methoden zur herstellung löslicher, oligomerer proteine
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
GB9722131D0 (en) 1997-10-20 1997-12-17 Medical Res Council Method
EP1105427A2 (en) 1998-08-17 2001-06-13 Abgenix, Inc. Generation of modified molecules with increased serum half-lives
GB9928787D0 (en) 1999-12-03 2000-02-02 Medical Res Council Direct screening method
AU2001268427B2 (en) 2000-06-16 2007-03-29 Glaxosmithkline Intellectual Property Limited Antibodies that immunospecifically bind to blys
US6938003B2 (en) 2000-06-30 2005-08-30 Mahesh Harpale Method and apparatus for a credibility reporting system to augment an online exchange
GB0025144D0 (en) 2000-10-13 2000-11-29 Medical Res Council Concatenated nucleic acid sequences
AU2002329540A1 (en) * 2001-06-20 2003-01-02 Morphosys Ag Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
US20040202995A1 (en) 2003-04-09 2004-10-14 Domantis Nucleic acids, proteins, and screening methods
DK2511297T3 (en) 2004-02-06 2015-06-15 Morphosys Ag Human anti-CD38 antibodies and their applications
CN1976950B (zh) * 2004-02-06 2012-08-29 莫佛塞斯公司 抗cd38人抗体及其用途
EP2567976B1 (en) * 2005-03-23 2017-07-19 Genmab A/S Antibodies against CD38 for treatment of multiple myeloma
EP2860192B1 (en) * 2005-10-12 2017-09-27 MorphoSys AG Generation and profiling of fully human HuCAL GOLD-derived therapeutic antibodies specific for human CD38
DK2356270T3 (da) 2008-11-07 2016-12-12 Fabrus Llc Kombinatoriske antistofbiblioteker og anvendelser deraf
WO2010141249A2 (en) * 2009-06-02 2010-12-09 Merck Sharp & Dohme Corp. Generation, characterization and uses thereof of anti-notch3 antibodies
DK2580243T3 (da) * 2010-06-09 2020-01-13 Genmab As Antibodies against human cd38
SI2621531T1 (sl) * 2010-09-27 2017-06-30 Morphosys Ag Anti-cd38 protitelo in lenalidomid ali bortezomib za zdravljenje multiplega mieloma in nhl
JOP20210044A1 (ar) * 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
US9120858B2 (en) * 2011-07-22 2015-09-01 The Research Foundation Of State University Of New York Antibodies to the B12-transcobalamin receptor
CA2919513A1 (en) * 2013-07-15 2015-01-22 Matthew J. Goldstein Medical uses of cd38 agonists
ES2927119T3 (es) 2015-04-08 2022-11-02 Sorrento Therapeutics Inc Productos terapéuticos de anticuerpos que se unen a CD38

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