JP2018512164A - 骨髄増殖性障害を処置するための方法 - Google Patents
骨髄増殖性障害を処置するための方法 Download PDFInfo
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- JP2018512164A JP2018512164A JP2017554345A JP2017554345A JP2018512164A JP 2018512164 A JP2018512164 A JP 2018512164A JP 2017554345 A JP2017554345 A JP 2017554345A JP 2017554345 A JP2017554345 A JP 2017554345A JP 2018512164 A JP2018512164 A JP 2018512164A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1716—Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/202—IL-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- General Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562148005P | 2015-04-15 | 2015-04-15 | |
| US62/148,005 | 2015-04-15 | ||
| US201562218869P | 2015-09-15 | 2015-09-15 | |
| US62/218,869 | 2015-09-15 | ||
| PCT/US2016/027773 WO2016168612A1 (en) | 2015-04-15 | 2016-04-15 | Methods for treating myeloproliferative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018512164A true JP2018512164A (ja) | 2018-05-17 |
| JP2018512164A5 JP2018512164A5 (https=) | 2019-05-23 |
Family
ID=57127338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017554345A Pending JP2018512164A (ja) | 2015-04-15 | 2016-04-15 | 骨髄増殖性障害を処置するための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20180318303A1 (https=) |
| EP (1) | EP3283655A4 (https=) |
| JP (1) | JP2018512164A (https=) |
| CN (1) | CN108138234A (https=) |
| AU (1) | AU2016248317A1 (https=) |
| CA (1) | CA2983004A1 (https=) |
| HK (2) | HK1250752A1 (https=) |
| RU (1) | RU2017139122A (https=) |
| WO (1) | WO2016168612A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021531793A (ja) * | 2018-07-31 | 2021-11-25 | ジェロン・コーポレーションGeron Corporation | テロメラーゼ阻害剤による治療から利益を得る可能性が高い患者を特定する方法 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9375485B2 (en) | 2012-12-07 | 2016-06-28 | Geron Corporation | Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms |
| CN105792831A (zh) | 2013-10-08 | 2016-07-20 | 普罗麦迪奥股份有限公司 | 用于治疗纤维化癌症的方法 |
| JP6852397B2 (ja) | 2016-12-28 | 2021-03-31 | 株式会社島津製作所 | 分析用試料の調製方法および分析方法 |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| EP3589750B1 (en) | 2017-03-01 | 2022-05-04 | The Board of Trustees of the Leland Stanford Junior University | Highly specific circular proximity ligation assay |
| DE102017107661A1 (de) * | 2017-04-10 | 2018-10-11 | Universität Rostock | SH2B-Adapterprotein-3 für die Vorhersage einer Knochenmarkantwort und Immunantwort |
| WO2019169290A1 (en) | 2018-03-02 | 2019-09-06 | Allogene Therapeutics, Inc. | Inducible chimeric cytokine receptors |
| KR101962869B1 (ko) * | 2018-08-02 | 2019-03-27 | 주식회사 우리메디칼 | 이미지 분석에 기반한 골수판독 지원 장치 |
| KR102900540B1 (ko) * | 2018-10-31 | 2025-12-17 | 스템라인 테라퓨틱스, 인코포레이티드 | 디프테리아 독소-인간 인터루킨-3 접합체를 다른 제제와 조합하여 사용해서 골수증식성 신생물을 치료하는 조합 치료 방법 |
| JP7695885B2 (ja) | 2019-02-12 | 2025-06-19 | アンブルックス,インコーポレイテッド | 抗体-tlrアゴニストコンジュゲートを含有する組成物、その方法、及び使用 |
| BR112021017365A2 (pt) | 2019-03-01 | 2022-02-01 | Allogene Therapeutics Inc | Receptores de citocina quiméricos constitutivamente ativos |
| EP3931208A1 (en) | 2019-03-01 | 2022-01-05 | Allogene Therapeutics, Inc. | Chimeric cytokine receptors bearing a pd-1 ectodomain |
| WO2021041806A1 (en) | 2019-08-30 | 2021-03-04 | Allogene Therapeutics, Inc. | Chimeric cytokine receptors comprising tgf beta binding domains |
| WO2021138391A1 (en) | 2019-12-30 | 2021-07-08 | Tyra Biosciences, Inc. | Indazole compounds |
| CN111471096B (zh) * | 2020-01-15 | 2022-02-18 | 上海众启生物科技有限公司 | 用于阿尔茨海默症自身抗体检测的含有adarb1蛋白片段组合物 |
| JP2023514407A (ja) | 2020-02-24 | 2023-04-05 | アロジーン セラピューティクス,インコーポレイテッド | 増強された活性を有するbcma car-t細胞 |
| EP3900789A1 (en) | 2020-04-23 | 2021-10-27 | Universitätsklinikum Jena | Pharmaceutical combination for the treatment of myeloproliferative neoplasms |
| CN113549597B (zh) * | 2021-07-22 | 2022-03-25 | 浙江大学 | 一种人原发性骨髓纤维化细胞株及其应用 |
| CN114752575B (zh) * | 2022-04-07 | 2023-06-13 | 内蒙古工业大学 | 一种nad+依赖性脱氢酶基因及其在提高辅酶q10产量中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2877013A1 (fr) * | 2004-10-27 | 2006-04-28 | Assist Publ Hopitaux De Paris | Indentification d'une mutation de jak2 impliquee dans la polyglobulie de vaquez |
| EP2987803B1 (en) * | 2009-06-17 | 2018-08-29 | Promedior Inc. | Sap variants and their use |
| CN105792831A (zh) * | 2013-10-08 | 2016-07-20 | 普罗麦迪奥股份有限公司 | 用于治疗纤维化癌症的方法 |
-
2016
- 2016-04-15 CA CA2983004A patent/CA2983004A1/en not_active Abandoned
- 2016-04-15 CN CN201680034923.6A patent/CN108138234A/zh active Pending
- 2016-04-15 WO PCT/US2016/027773 patent/WO2016168612A1/en not_active Ceased
- 2016-04-15 HK HK18110217.6A patent/HK1250752A1/zh unknown
- 2016-04-15 RU RU2017139122A patent/RU2017139122A/ru unknown
- 2016-04-15 EP EP16780843.5A patent/EP3283655A4/en not_active Withdrawn
- 2016-04-15 JP JP2017554345A patent/JP2018512164A/ja active Pending
- 2016-04-15 AU AU2016248317A patent/AU2016248317A1/en not_active Abandoned
- 2016-04-15 US US15/566,692 patent/US20180318303A1/en not_active Abandoned
- 2016-04-15 HK HK18115088.1A patent/HK1256036A1/zh unknown
Non-Patent Citations (5)
| Title |
|---|
| "Promedior Presents Positive Phase 2 Data for PRM-151 in Myelofibrosis at ASH Annual Meeting", BUSINESSWIRE, JPN6020017621, 2014, ISSN: 0004405063 * |
| TEFFERI, A. ET AL., LEUKEMIA, vol. 28, no. 7, JPN6020017626, 2014, pages 1472 - 7, ISSN: 0004405066 * |
| VAINCHENKER, W. ET AL., BLOOD, vol. 118, no. 7, JPN6020017624, 2011, pages 1723 - 35, ISSN: 0004405065 * |
| VANNUCCHI, A.M. ET AL., BLOOD, vol. 124, no. 21, JPN6020017623, 2014, pages 405, ISSN: 0004405064 * |
| VANNUCCHI, A.M. ET AL., THER ADV HEMATOL, vol. 2, no. 1, JPN6020017628, 2011, pages 21 - 32, ISSN: 0004405067 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021531793A (ja) * | 2018-07-31 | 2021-11-25 | ジェロン・コーポレーションGeron Corporation | テロメラーゼ阻害剤による治療から利益を得る可能性が高い患者を特定する方法 |
| JP7401518B2 (ja) | 2018-07-31 | 2023-12-19 | ジェロン・コーポレーション | テロメラーゼ阻害剤による治療から利益を得る可能性が高い患者を特定する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108138234A (zh) | 2018-06-08 |
| CA2983004A1 (en) | 2016-10-20 |
| HK1250752A1 (zh) | 2019-01-11 |
| AU2016248317A1 (en) | 2017-11-09 |
| US20180318303A1 (en) | 2018-11-08 |
| EP3283655A1 (en) | 2018-02-21 |
| RU2017139122A (ru) | 2019-05-15 |
| WO2016168612A1 (en) | 2016-10-20 |
| RU2017139122A3 (https=) | 2019-08-28 |
| EP3283655A4 (en) | 2018-12-05 |
| HK1256036A1 (zh) | 2019-09-13 |
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