JP2018509471A - パーソナルケア製品のための粘度増強組成物 - Google Patents
パーソナルケア製品のための粘度増強組成物 Download PDFInfo
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- JP2018509471A JP2018509471A JP2018501143A JP2018501143A JP2018509471A JP 2018509471 A JP2018509471 A JP 2018509471A JP 2018501143 A JP2018501143 A JP 2018501143A JP 2018501143 A JP2018501143 A JP 2018501143A JP 2018509471 A JP2018509471 A JP 2018509471A
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- Prior art keywords
- polyglyceryl
- viscosity enhancing
- enhancing composition
- ester
- personal care
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- HWCHICTXVOMIIF-UHFFFAOYSA-M sodium;3-(dodecylamino)propanoate Chemical compound [Na+].CCCCCCCCCCCCNCCC([O-])=O HWCHICTXVOMIIF-UHFFFAOYSA-M 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
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- 229960002256 spironolactone Drugs 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 229940057981 stearalkonium chloride Drugs 0.000 description 1
- SFVFIFLLYFPGHH-UHFFFAOYSA-M stearalkonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 SFVFIFLLYFPGHH-UHFFFAOYSA-M 0.000 description 1
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- 229940012831 stearyl alcohol Drugs 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
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- 230000001180 sulfating effect Effects 0.000 description 1
- 229940117986 sulfobetaine Drugs 0.000 description 1
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- 150000003462 sulfoxides Chemical class 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
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- 229960000351 terfenadine Drugs 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
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- 235000019157 thiamine Nutrition 0.000 description 1
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- FAGMGMRSURYROS-UHFFFAOYSA-M trihexadecyl(methyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(CCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCC FAGMGMRSURYROS-UHFFFAOYSA-M 0.000 description 1
- IRYJRGCIQBGHIV-UHFFFAOYSA-N trimethadione Chemical compound CN1C(=O)OC(C)(C)C1=O IRYJRGCIQBGHIV-UHFFFAOYSA-N 0.000 description 1
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- SYHDSBBKRLVLFF-UHFFFAOYSA-N triparanol Chemical compound C1=CC(OCCN(CC)CC)=CC=C1C(O)(C=1C=CC(C)=CC=1)CC1=CC=C(Cl)C=C1 SYHDSBBKRLVLFF-UHFFFAOYSA-N 0.000 description 1
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- 239000004474 valine Substances 0.000 description 1
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- 235000013311 vegetables Nutrition 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- 150000002266 vitamin A derivatives Chemical class 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 229940084883 wheat amino acids Drugs 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 1
- 229960002555 zidovudine Drugs 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 229960001296 zinc oxide Drugs 0.000 description 1
- 229940043810 zinc pyrithione Drugs 0.000 description 1
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical compound [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/85—Polyesters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
Description
[0001]本出願は、2015年8月25日提出の米国仮特許出願第62/209667号及び2015年3月27日提出の米国仮特許出願第62/139089号に基づき、これらに対する優先権を主張するものであり、これらを本明細書において援用する。
[0002]多くのさまざまなパーソナルケア製品が市場に存在する。そのようなパーソナルケア製品としては、シャンプー、コンディショナー、化粧品、手用保湿剤、ボディクリーム、シャワージェル、及び他の洗浄剤などが挙げられる。これらの製品の大部分は、体の特定部分に施用するためのものである。市場性の高いものにするには、これらの製品は、使用目的によく適していることに加え、特定の厳しい要件を満たしていなければならない。例えば、これらの製品の多くは、良い香りを有するか無香でなければならず、均一な粘稠度を有していなければならず、制御された粘度で表面に均等に施用されなければならない。典型的には、より濃厚なパーソナルケア製品は高級品とされており、したがって、より望ましい。
[0005]上記を考慮して、当業者らは、製品の粘度を望ましいレベルに増大させるために最小量で加えることができる、より良好な増粘剤又は粘度増強組成物(viscosity building composition)を開発しようと試みてきた。この点で、本開示は、改善された粘度増強組成物を対象とする。
[0015]本開示の粘度増強組成物は、あらゆる種類のパーソナルケア製品における使用に非常に適している。例えば、粘度増強組成物は、シャンプー、ボディウォッシュ、コンディショナー、化粧品、スキンクリーム、薬物、顔用クレンザー、皮膚用クレンザー、ハンドクリーム、日焼け止めローション、化粧落とし、ボディローションなどに組み込むことができる。1つの態様では、パーソナルケア製品は、エモリエント剤、保湿剤、及び少なくとも1種の界面活性剤を含有する。
[0019]他の態様では、パーソナルケア製品は、化粧品を含むことができる。1つの態様では、パーソナルケア製品は、アニオン性界面活性剤及び両性イオン性界面活性剤を含有することができる。
図面の簡単な説明
[0021]本開示の完全かつ権能付与的開示を、本明細書の残りの部分で、添付の図面を参照することを含めて、より詳細に説明する。
[0022]本考察は代表的態様の解説に過ぎず、本開示の広範囲な観点を制限することを意図するものではないことを、当業者なら理解すべきである。
R5OCH2−CH(OR4)−CH2−(O−CH2CH(OR3)−CH2)n−O−CH2−CH(OR2)−CH2OR1、
[式中、Rは、水素、又は炭素原子4〜36個の脂肪酸部分のアシル基(R−CO−)であり、R基の数は、1〜14、例えば1〜12であり、nは2〜14、例えば3〜10である]。
[0054]C10〜C16脂肪酸から誘導されるアルキル基を有する他のアルキルアミドプロピルベタインを用いてもよい。対応するアルキルアミドプロピルスルタイン(sultaine)、特にコカミドプロピルスルタインも許容可能である。
4−[N,N−ジ(2−ヒドロキシエチル)−N−オクタデシルアンモニオ]−ブタン−1−カルボキシレート;
5−[S−3−ヒドロキシプロピル−S−ヘキサデシルスルホニオ]−3−ヒドロキシペンタン−1−スルフェート;
3−[P,P−ジエチル−P−3,6,9−トリオキサテトラデコキシルホスホニオ]−2−ヒドロキシプロパン−1−ホスフェート;
3−[N,N−ジプロピル−N−3−ドデコキシ−2−ヒドロキシプロピルアンモニオ]−プロパン−1−ホスホネート;
3−(N,N−ジメチル−N−ヘキサデシルアンモニオ)プロパン−1−スルホネート;
3−(N,N−ジメチル−N−ヘキサデシルアンモニオ)−2−ヒドロキシプロパン−1−スルホネート;
4−[N,N−ジ(2−ヒドロキシエチル)−N−(2−ヒドロキシドデシル)アンモニオ]−ブタン−1−カルボキシレート;
3−[S−エチル−S−(3−ドデコキシ−2−ヒドロキシプロピル)スルホニオ]−プロパン−1−ホスフェート;
3−[P,P−ジメチル−P−ドデシルホスホニオ]−プロパン−1−ホスホネート;及び
5−[N,N−ジ(3−ヒドロキシプロピル)−N−ヘキサデシルアンモニオ]−2−ヒドロキシペンタン−1−スルフェート;
が挙げられる。
ココジメチルカルボキシメチルベタイン、
ラウリルジメチルカルボキシメチルベタイン、
ラウリルジメチルα−カルボキシエチルベタイン、
セチルジメチルカルボキシメチルベタイン、
ラウリルビス−(2−ヒドロキシエチル)カルボキシメチルベタイン、
ステアリルビス−(2−ヒドロキシプロピル)カルボキシメチルベタイン、
オレイルジメチルγ−カルボキシプロピルベタイン、
ラウリルビス−(2−ヒドロキシプロピル)α−カルボキシエチルベタイン、
などが挙げられる。
ココジメチルスルホプロピルベタイン、
ステアリルジメチルスルホプロピルベタイン、
ラウリルジメチルスルホエチルベタイン、
ラウリルビス−(2−ヒドロキシエチル)スルホプロピルベタイン、
などにより表すことができる。RCONH(CH2)3基がベタインの窒素原子に結合しているアミドベタイン及びアミドスルホベタインを用いることもできる。
[0061]両性界面活性剤の例は、脂肪族基が直鎖又は分枝鎖であり、脂肪族置換基のうち1つが約8〜18個の炭素原子を含有し、1つがアニオン性可水溶化基、例えば、カルボキシ、スルホネート、スルフェート、ホスフェート、又はホスホネートを含有する、脂肪族第2級及び第3級アミンの誘導体である。これらの化合物の例は、ナトリウム3−ドデシルアミノプロピオネート、ナトリウム3−ドデシルアミノプロパンスルホネート、及び、ドデシルアミンとイセチオン酸ナトリウムとの反応生成物などのN−アルキルタウリン、及びN−高級アルキルアスパラギン酸である。
1. 以下の一般式に相当する長鎖第3級アミンオキシド:
R1R2R3N → O
[式中、R1は、炭素原子約8〜約18個のアルキル、アルケニル、又はモノヒドロキシアルキル基、最大約10個のエチレンオキシド部分、及び最大1個のグリセリル部分を含有し、R2及びR3は、1〜約3個の炭素原子及び最大約1個のヒドロキシ基を含有し、例えば、メチル、エチル、プロピル、ヒドロキシエチル、又はヒドロキシプロピル基である]。本発明における使用に適したアミンオキシドの例としては、以下が挙げられる:
ジメチルドデシルアミンオキシド、
オレイルジ(2−ヒドロキシエチル)アミンオキシド、
ジメチルオクチルアミンオキシド、
ジメチルデシルアミンオキシド、
ジメチルテトラデシルアミンオキシド、
3,6,9−トリオキサヘプタデシルジエチルアミンオキシド、
ジ(2−ヒドロキシエチル)テトラデシルアミンオキシド、
2−ドデコキシエチルジメチルアミンオキシド、
3−ドデコキシ−2−ヒドロキシプロピルジ(3−ヒドロキシプロピル)アミンオキシド、及び
ジメチルヘキサデシルアミンオキシド。
2. 以下の一般式に相当する長鎖第3級ホスフィンオキシド:
RR’R”P → O
[式中、Rは、鎖長中の炭素原子が8〜18個であるアルキル、アルケニル、又はモノヒドロキシアルキル基、最大約10個のエチレンオキシド部分、及び最大1個のグリセリル部分を含有し、R’及びR”は、それぞれ、1〜3個の炭素原子を含有するアルキル又はモノヒドロキシアルキル基である]。適したホスフィンオキシドの例は以下である:
ドデシルジメチルホスフィンオキシド、
テトラデシルジメチルホスフィンオキシド、
テトラデシルメチルエチルホスフィンオキシド、
3,6,9−トリオキサオクタデシルジメチルホスフィンオキシド、
セチルジメチルホスフィンオキシド、
3−ドデコキシ−2−ヒドロキシプロピルジ(2−ヒドロキシエチル)ホスフィンオキシド、
ステアリルジメチルホスフィンオキシド、
セチルエチルプロピルホスフィンオキシド、
オレイルジエチルホスフィンオキシド、
ドデシルジエチルホスフィンオキシド、
テトラデシルジエチルホスフィンオキシド、
ドデシルジプロピルホスフィンオキシド、
ドデシルジ(ヒドロキシメチル)ホスフィンオキシド、
ドデシルジ(2−ヒドロキシエチル)ホスフィンオキシド、
テトラデシルメチル−2−ヒドロキシプロピルホスフィンオキシド、
オレイルジメチルホスフィンオキシド、及び
2−ヒドロキシドデシルジメチルホスフィンオキシド。
3. 炭素原子1〜約3個の短鎖アルキル又はヒドロキシアルキル基(通常メチル)を1個と、約8〜約20個の炭素原子を含有するアルキル、アルケニル、ヒドロキシアルキル、又はケトアルキル基、最大約10個のエチレンオキシド部分、及び最大1個のグリセリル部分を含有する1本の疎水性長鎖とを含有する、長鎖ジアルキルスルホキシド。例としては、オクタデシルメチルスルホキシド、2−ケトトリデシルメチルスルホキシド、3,6,9−トリオキサオクタデシル2−ヒドロキシエチルスルホキシド、ドデシルメチルスルホキシド、オレイル3−ヒドロキシプロピルスルホキシド、テトラデシルメチルスルホキシド、3−メトキシトリデシルメチルスルホキシド、3−ヒドロキシトリデシルメチルスルホキシド、3−ヒドロキシ−4−ドデコキシブチルメチルスルホキシドが挙げられる。
HO−(R”O)b−H VI
[式中:R”は約2〜約4個の炭素原子を有するアルキレン基であり、bは約1〜約10の整数である]、例えばPEG4;3)式VIIのメチルグルコースのポリエチレングリコールエーテル:
CH3−C6H10O5−(OCH2CH2)c−OH VII
[式中:cは約5〜約25の整数である];4)尿素;5)フルクトース;6)グルコース;7)ハチミツ;8)乳酸;9)マルトース;10)グルクロン酸ナトリウム;及び11)それらの混合物が挙げられる。
[0081]皮膚美白剤の例としては、非排他的に、ハイドロキノン、カテコール及びその誘導体、アスコルビン酸及びその誘導体、並びにそれらの混合物が挙げられる。
R5は、炭素原子約1〜約6個の分枝鎖又は非分枝鎖アルキル基であり;
R6は、H、メチル、又はエチルであり;
R7は、炭素原子約1〜約8個の分枝鎖若しくは非分枝鎖アルキル基、又はアルコキシ基であり;
Kは、−CN基又はCOOR8基であり、ここで、
R8は、炭素原子約1〜約6個の分枝鎖又は非分枝鎖アルキル基である];
天然又は合成ピレスロイド、ここで、天然ピレスロイドは、除虫菊、すなわちシロバナムシヨケギク又はアカバナムシヨケギクの磨砕した花の抽出物に含有される;及びそれらの混合物が挙げられる。式VIIIの構造物には、R7がCH3基であり、R5がn−ブチル基であり、R6がHであり、KがCOOR8であり、R8がエチルである場合のエチル3−(N−ブチルアセトアミド)プロピオネートがあり、これは、ドイツ、ダルムシュタットのメルク社から「インセクトリペレント3535」の名称で市販されている。
[0084]適した脱毛剤の例としては、非排他的に、チオグリコール酸カルシウム、チオグリコール酸マグネシウム、チオグリコール酸カリウム、チオグリコール酸ストロンチウム、及びそれらの混合物が挙げられる。
[0089]適した痔疾薬の例としては、非排他的に、麻酔薬、例えば、ベンゾカイン、塩酸プラモキシン、及びそれらの混合物;塩化ベンゼトニウムなどの消毒剤;収斂剤、例えば、酸化亜鉛、次没食子酸ビスマス、バルサムペルー、及びそれらの混合物;皮膚保護薬、例えば、肝油、植物油、及びそれらの混合物が挙げられる。
[0099]本開示の利益及び利点のいくつかを実証するために、以下の組成物を配合した。
[00100]0.75%のフェノキシエタノール、クロルフェネシン、及びカプリリルグリコールのブレンド(MikrokillTM COS)、及び1.5又は3%のセチルステアリルアルコール、及び1又は2%の乳化剤の組合せを有する、(1)3%グリセリン、0.25%キサンタンガム、7.5%カプリル/カプリントリグリセリド(「CCT」)、及び7.5%シアバター、又は(2)9%炭酸ジカプリリル(LONZEST DC)及び6%ホホバ油、の皮膚ベース配合物を調製した。
[00102]以下の表1において、以下の表示を用いてグリセリルエステルを識別する:
X−Y−Z
ここで、Xはグリセリル分子の数である。Yはエステル基の数を表す。例えば、1はモノエステルを示し、2はジエステルを示し、以下同様である。Zは、ポリグリセリルエステルを構築するのに用いられる脂肪酸を識別する。Sはステアレートを表し、Oはオレエートを表す。以下に示すように、モノエステルとポリエステルとの重量比を変えることにより、HLB数を著しく変化させることができる。1つの態様では、ポリグリセリルエステルは、製品中の1種以上の成分、例えば製品の油相のHLB数に実質的に匹敵するHLB数を有するように配合することができる。
[00109]代表例を示す目的に過ぎないが、以下は本開示に従って作製することができるパーソナルケア製品の態様である。以下の製品は、活性剤としてピリチオンを含有するボディウォッシュを表す。
実施例3
[00112]代表例を示す目的に過ぎないが、以下は本開示に従って作製した他のボディウォッシュ配合物である:
実施例4
[00114]本開示の利益及び利点のいくつかをさらに実証するために、以下の組成物を配合した。
X−Y−Z
ここで、Xはグリセリル分子の数である。Yはエステル基の数をさす。例えば、1はモノエステルを示し、2はジエステルを示し、以下同様である。Zは、ポリグリセリルエステルを構築するのに用いられる脂肪酸を識別する。Sはステアレートを表し、Oはオレエートを表す。
Claims (35)
- 少なくとも1種のポリグリセリルエステルと組み合わせた脂肪族アルコールを含み、該脂肪族アルコール及び少なくとも1種のポリグリセリルエステルが、約2:1〜約1:10の重量比で組成物中に存在する、粘度増強組成物。
- 請求項1に定義した粘度増強組成物を含み、さらにピリチオンを含有する、パーソナルケア製品。
- 組成物が、単一種類のポリグリセリルエステルのみを含有する、請求項1に定義した粘度増強組成物。
- 単一種類のポリグリセリルエステルが、1種以上のポリグリセリルモノエステルを含む、請求項3に定義した粘度増強組成物。
- 単一種類のポリグリセリルエステルが、1種以上のポリグリセリルポリエステルを含む、請求項3に定義した粘度増強組成物。
- ポリグリセリルジパルミテート及びポリグリセリルジステアレートを含有する、請求項5に定義した粘度増強組成物。
- ポリグリセリルジパルミテートが、ポリグリセリルジステアレートに対して約2:1〜約1:40、例えば約1:1〜約1:30、例えば約1:2〜約1:25の重量比で存在する、請求項6に定義した粘度増強組成物。
- ポリグリセリルポリエステルが、約6〜約7.5のHLBを有するように組み合わされる、請求項4〜7のいずれかに定義した粘度増強組成物。
- 1種以上のポリグリセリルポリエステルが、少なくとも1種のポリグリセリルジエステルを含む、請求項5に定義した粘度増強組成物。
- 1種以上の脂肪族アルコール及び1種以上のポリグリセリルエステルから成る、請求項1に定義した粘度増強組成物。
- エモリエント剤、保湿剤、界面活性剤、及び請求項10に定義した粘度増強組成物を含有する、パーソナルケア製品。
- 脂肪族アルコール;
脂肪酸のポリグリセリルモノエステルを含む第1のポリグリセリルエステル;及び
脂肪酸のポリグリセリルポリエステルを含む少なくとも1種の第2のポリグリセリルエステル;
を含む粘度増強組成物であって、組成物中の第1のポリグリセリルエステルの第2のポリグリセリルエステルに対する重量比が約1:100〜約100:1である、前記粘度増強組成物。 - 第1のポリグリセリルエステルの少なくとも1種の第2のポリグリセリルエステルに対する重量比が、約1:50〜約1:1、例えば約1:35〜約2:3である、請求項12に定義した粘度増強組成物。
- 脂肪族アルコールのすべてのポリグリセリルエステルに対する重量比が、約1:10〜約10:1、例えば約1:5〜約10:1、例えば約1:1〜約5:1である、請求項1〜13のいずれかに定義した粘度増強組成物。
- 第1のポリグリセリルエステル及び少なくとも1種の第2のポリグリセリルエステルが、炭素原子約6個〜約26個の炭素鎖長を有する脂肪酸のポリグリセリルエステルである、請求項12に定義した粘度増強組成物。
- 第2のポリグリセリルエステルが、少なくとも1種のポリグリセリルジエステルを含む、請求項12に定義した粘度増強組成物。
- ポリグリセリルエステルがそれぞれ、化合物1個あたり約2〜約12個のグリセロール分子を含有する、請求項1〜16のいずれかに定義した粘度増強組成物。
- 第1のポリグリセリルエステルがポリグリセリルモノステアレートを含み、第2のポリグリセリルエステルがポリグリセリルジステアレートを含む、請求項12に定義した粘度増強組成物。
- ポリグリセリルエステルが、ポリグリセリルモノステアレート、ポリグリセリルモノデカオレエート、ポリグリセリルモノオレエート、及びそれらの混合物を含む、請求項1に定義した粘度増強組成物。
- 脂肪族アルコールが、炭素原子約4個〜約36個、例えば炭素原子約6個〜約28個の炭素鎖長を有する、請求項1〜19のいずれかに定義した粘度増強組成物。
- 脂肪族アルコールが、脂肪族アルコールの混合物を含む、請求項1〜20のいずれかに定義した粘度増強組成物。
- 脂肪族アルコールが、セチルアルコール、ステアリルアルコール、ラウリルアルコール、ミリスチルアルコール、ベヘニルアルコール、又はそれらの混合物を含む、請求項1〜21のいずれかに定義した粘度増強組成物。
- 少なくとも1種のポリグリセリルエステルが飽和脂肪酸から作製される、請求項1〜22のいずれかに定義した粘度増強組成物。
- 第2のポリグリセリルエステルが飽和脂肪酸から作製される、請求項12に定義した粘度増強組成物。
- 請求項1〜24のいずれかに定義した粘度増強組成物を含有するパーソナルケア製品。
- エモリエント剤、保湿剤、及び少なくとも1種の界面活性剤を含有する、請求項25に定義したパーソナルケア製品。
- 脂肪族アルコールを、約5重量%未満、例えば約4重量%未満、例えば約3重量%未満、例えば約2重量%未満の量で含有する、請求項25又は26に定義したパーソナルケア製品。
- 第1のポリグリセリルエステル及び少なくとも1種の第2のポリグリセリルエステルが両方とも、約0.5重量%を超える量、例えば約0.75重量%を超える量、例えば約1重量%を超える量、例えば約1.25重量%を超える量、例えば約1.5重量%を超える量、例えば約2重量%を超える量、及び約10重量%未満の量、例えば約8重量%未満の量、例えば約6重量%未満の量、例えば約4重量%未満の量で製品中に含有される、請求項25、26、又は27に定義したパーソナルケア製品。
- 水を含む液体キャリヤーをさらに含む、請求項25、26、27、又は28に定義したパーソナルケア製品。
- シャンプーを含む、請求項25、26、27、28、又は29に定義したパーソナルケア製品。
- ピリチオンをさらに含む、請求項30に定義したパーソナルケア製品。
- 化粧品を含む、請求項25、26、27、28、又は29に定義したパーソナルケア製品。
- アニオン性界面活性剤及び両性イオン性界面活性剤を含有する、請求項25、26、27、28、29、30、31、又は32に定義したパーソナルケア製品。
- 請求項1、3〜10、又は12〜24のいずれかに定義した粘度増強組成物を含有するエマルション。
- エモリエント剤、保湿剤、及び界面活性剤を含有する、請求項2に定義したパーソナルケア製品。
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DE4330597A1 (de) | 1992-10-14 | 1995-03-16 | Ahmad Khalil | Haarwuchssystem und Haarwasser gegen Haarausfall |
JPH072677A (ja) | 1993-06-18 | 1995-01-06 | Toyo Seito Kk | 経口育毛剤 |
DE69630221T2 (de) | 1995-06-22 | 2004-07-15 | Minnesota Mining And Mfg. Co., Saint Paul | Stabile alkoholisch-wässrige zusammensetzung |
US9381382B2 (en) | 2002-06-04 | 2016-07-05 | The Procter & Gamble Company | Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network |
CA2593537A1 (en) * | 2005-01-12 | 2006-07-20 | S.U.L.V.E. Ltd. | Methods and pharmaceutical compositions useful for treating psoriasis |
WO2010019727A1 (en) | 2008-08-15 | 2010-02-18 | The Procter & Gamble Company | Benefit compositions comprising polyglycerol esters |
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2016
- 2016-03-22 EP EP16712692.9A patent/EP3274054A1/en not_active Withdrawn
- 2016-03-22 CN CN201680025366.1A patent/CN107548302A/zh active Pending
- 2016-03-22 KR KR1020177031071A patent/KR20170131641A/ko unknown
- 2016-03-22 WO PCT/US2016/023538 patent/WO2016160412A1/en active Application Filing
- 2016-03-22 JP JP2018501143A patent/JP6763939B2/ja not_active Expired - Fee Related
- 2016-03-22 US US15/076,853 patent/US9867769B2/en not_active Expired - Fee Related
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2018
- 2018-01-05 US US15/862,982 patent/US10064809B2/en not_active Expired - Fee Related
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JPH08337513A (ja) * | 1995-06-13 | 1996-12-24 | Shiseido Co Ltd | 撥水性水中油型乳化組成物 |
JP2003507343A (ja) * | 1999-08-17 | 2003-02-25 | ガレナ・アクティーゼルスカブ | 経口及び局所投与用の医薬組成物 |
JP2003063922A (ja) * | 2001-08-22 | 2003-03-05 | Masato Tagawa | 皮膚外用剤用組成物、パール化物、及び、皮膚外用剤 |
JP2004189693A (ja) * | 2002-12-13 | 2004-07-08 | Kao Corp | 水中油型乳化化粧料 |
JP2006519769A (ja) * | 2003-03-18 | 2006-08-31 | ザ プロクター アンド ギャンブル カンパニー | ピリチオンの活性又はピリチオンの多価金属塩の活性の、亜鉛含有層状物質による増幅 |
JP2005068034A (ja) * | 2003-08-20 | 2005-03-17 | Pola Chem Ind Inc | クレンジングフォーム |
Also Published As
Publication number | Publication date |
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JP6763939B2 (ja) | 2020-09-30 |
US20160279050A1 (en) | 2016-09-29 |
WO2016160412A1 (en) | 2016-10-06 |
KR20170131641A (ko) | 2017-11-29 |
US20180140533A1 (en) | 2018-05-24 |
CN107548302A (zh) | 2018-01-05 |
EP3274054A1 (en) | 2018-01-31 |
US9867769B2 (en) | 2018-01-16 |
US10064809B2 (en) | 2018-09-04 |
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