JP2018507910A - 神経芽細胞腫を治療する方法 - Google Patents

神経芽細胞腫を治療する方法 Download PDF

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JP2018507910A
JP2018507910A JP2017560893A JP2017560893A JP2018507910A JP 2018507910 A JP2018507910 A JP 2018507910A JP 2017560893 A JP2017560893 A JP 2017560893A JP 2017560893 A JP2017560893 A JP 2017560893A JP 2018507910 A JP2018507910 A JP 2018507910A
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patient
dfmo
genotype
odc1
cancer
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JP2018507910A5 (enExample
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ユージーン・ガーナー
エリザベス・ブラックハイマー
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ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ジ・ユニバーシティ・オブ・アリゾナ
キャンサー・プリヴェンション・ファーマシューティカルズ・インコーポレイテッド
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Q2600/00—Oligonucleotides characterized by their use
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Hospice & Palliative Care (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2017560893A 2015-02-12 2016-02-12 神経芽細胞腫を治療する方法 Pending JP2018507910A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562115413P 2015-02-12 2015-02-12
US62/115,413 2015-02-12
US201562154804P 2015-04-30 2015-04-30
US62/154,804 2015-04-30
PCT/US2016/017751 WO2016130918A1 (en) 2015-02-12 2016-02-12 Methods for treating neuroblastoma

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JP2018507910A true JP2018507910A (ja) 2018-03-22
JP2018507910A5 JP2018507910A5 (enExample) 2019-03-22

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EP (1) EP3256117A4 (enExample)
JP (1) JP2018507910A (enExample)
CA (1) CA2976106A1 (enExample)
HK (1) HK1248133A1 (enExample)
WO (1) WO2016130918A1 (enExample)

Cited By (2)

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JP2022505849A (ja) * 2018-10-24 2022-01-14 ナビター ファーマシューティカルズ， インコーポレイテッド 多形化合物およびその使用
JP2022532766A (ja) * 2019-05-17 2022-07-19 キャンサー プリベンション ファーマシューティカルズ，インコーポレイテッド 家族性腺腫性ポリポーシスを処置するための方法

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LT2912193T (lt) 2012-10-29 2018-12-27 Arizona Board Of Regents On Behalf Of University Of Arizona Prognozuojami žymenys, skirti vėžio terapijoms poliamino inhibitoriumi
WO2015195120A1 (en) 2014-06-18 2015-12-23 Arizona Board Of Regents On Behalf Of University Of Arizona Carcinoma diagnosis and treatment based on odc1 genotype
MX390899B (es) 2015-10-30 2025-03-21 Cancer Prevention Pharmaceuticals Inc Formulación de combinación de dosis fija, eflornitina y sulindaco.
US12042477B2 (en) 2016-02-23 2024-07-23 Cancer Research Technology Limited Dietary product devoid of at least two non essential amino acids
IL314380A (en) * 2016-10-06 2024-09-01 Orbus Therapeutics Inc Preparations for administration of aflornithine
JP2023530235A (ja) 2020-06-03 2023-07-14 フェス・セラピューティクス，インコーポレーテッド 個別化された処置方法のための製剤
JP2023528930A (ja) 2020-06-04 2023-07-06 フェス・セラピューティクス，インコーポレーテッド がんを処置する個別化された方法
EP4618967A1 (en) 2022-11-20 2025-09-24 Universität Zürich Combination of polyamine pathway inhibitor drug and proline/arginine diet restriction

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LT2912193T (lt) * 2012-10-29 2018-12-27 Arizona Board Of Regents On Behalf Of University Of Arizona Prognozuojami žymenys, skirti vėžio terapijoms poliamino inhibitoriumi
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JP2002526468A (ja) * 1998-09-23 2002-08-20 ロンザ アーゲー （−）−α−ジフルオロメチルオルニチン・モノハイドロクロライド・一水和物の製造方法
JP2005501881A (ja) * 2001-08-29 2005-01-20 ウィメン・ファースト・ヘルスケアー・インコーポレーテッド α−ジフルオロメチルオルニチン（ＤＦＭＯ）の製造方法
JP2007537719A (ja) * 2004-01-22 2007-12-27 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング 補体結合が低下した抗癌抗体
JP2010505909A (ja) * 2006-10-10 2010-02-25 ユニベルシテ ドゥ ナント 癌を治療するための、ｏ−アセチル化型のｇｄ２ガングリオシドに特異的なモノクローナル抗体の使用
JP2012526852A (ja) * 2009-05-14 2012-11-01 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニバーシティー オブ アリゾナ Ｏｄｃ１の遺伝子型に基づく癌腫診断及び治療
WO2014144763A2 (en) * 2013-03-15 2014-09-18 Memorial Sloan Kettering Cancer Center High affinity anti-gd2 antibodies

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022505849A (ja) * 2018-10-24 2022-01-14 ナビター ファーマシューティカルズ， インコーポレイテッド 多形化合物およびその使用
JP7644002B2 (ja) 2018-10-24 2025-03-11 ナビター ファーマシューティカルズ， インコーポレイテッド 多形化合物およびその使用
JP2022532766A (ja) * 2019-05-17 2022-07-19 キャンサー プリベンション ファーマシューティカルズ，インコーポレイテッド 家族性腺腫性ポリポーシスを処置するための方法

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US20190046484A1 (en) 2019-02-14
EP3256117A1 (en) 2017-12-20
EP3256117A4 (en) 2018-10-10
HK1248133A1 (zh) 2018-10-12
US20240165063A1 (en) 2024-05-23
CA2976106A1 (en) 2016-08-18
WO2016130918A1 (en) 2016-08-18
US20250127742A1 (en) 2025-04-24
US20210378999A1 (en) 2021-12-09

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