JP2018507689A5 - - Google Patents

Download PDF

Info

Publication number
JP2018507689A5
JP2018507689A5 JP2017542470A JP2017542470A JP2018507689A5 JP 2018507689 A5 JP2018507689 A5 JP 2018507689A5 JP 2017542470 A JP2017542470 A JP 2017542470A JP 2017542470 A JP2017542470 A JP 2017542470A JP 2018507689 A5 JP2018507689 A5 JP 2018507689A5
Authority
JP
Japan
Prior art keywords
peptide
xaa
linker
seq
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017542470A
Other languages
English (en)
Japanese (ja)
Other versions
JP7028643B2 (ja
JP2018507689A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/SG2016/050079 external-priority patent/WO2016130092A1/en
Publication of JP2018507689A publication Critical patent/JP2018507689A/ja
Publication of JP2018507689A5 publication Critical patent/JP2018507689A5/ja
Application granted granted Critical
Publication of JP7028643B2 publication Critical patent/JP7028643B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017542470A 2015-02-13 2016-02-15 膜を破壊しないp53活性化ステープルペプチド Active JP7028643B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10201501119W 2015-02-13
SG10201501119W 2015-02-13
PCT/SG2016/050079 WO2016130092A1 (en) 2015-02-13 2016-02-15 Non-membrane disruptive p53 activating stapled peptides

Publications (3)

Publication Number Publication Date
JP2018507689A JP2018507689A (ja) 2018-03-22
JP2018507689A5 true JP2018507689A5 (cg-RX-API-DMAC7.html) 2019-03-28
JP7028643B2 JP7028643B2 (ja) 2022-03-02

Family

ID=56614951

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017542470A Active JP7028643B2 (ja) 2015-02-13 2016-02-15 膜を破壊しないp53活性化ステープルペプチド

Country Status (6)

Country Link
US (1) US11319344B2 (cg-RX-API-DMAC7.html)
EP (1) EP3256484B1 (cg-RX-API-DMAC7.html)
JP (1) JP7028643B2 (cg-RX-API-DMAC7.html)
CN (1) CN107531759B (cg-RX-API-DMAC7.html)
SG (1) SG11201706562QA (cg-RX-API-DMAC7.html)
WO (1) WO2016130092A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121064336A (zh) * 2018-07-31 2025-12-05 雷莫内克斯生物制药有限公司 多肽递送组合物
WO2020027585A2 (ko) * 2018-07-31 2020-02-06 주식회사 레모넥스 폴리펩타이드 전달용 조성물
CN115052614B (zh) * 2019-12-05 2025-10-21 亚洲大学校产学协力团 包含肽或其混合物作为活性成分的用于预防或治疗白塞氏病和类风湿性关节炎的药物组合物
CN111613275B (zh) * 2020-05-26 2021-03-16 中国海洋大学 一种基于rmsd多特征的药物分子动力学结果分析方法
IT202000016807A1 (it) * 2020-07-10 2022-01-10 Humanitas Mirasole Spa Peptidi associati a tumore e loro impiego
CN116801908A (zh) 2020-10-14 2023-09-22 丹娜法伯癌症研究院 用于降解病毒和宿主蛋白的嵌合缀合物和使用方法
WO2024051616A1 (zh) * 2022-09-09 2024-03-14 湖南大学 一种多肽及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009149339A2 (en) * 2008-06-05 2009-12-10 University Of Maryland, Baltimore P53 activator peptides
KR20120053042A (ko) * 2009-08-17 2012-05-24 로슈 글리카트 아게 표적화된 면역접합체
US20120328692A1 (en) * 2011-06-24 2012-12-27 University Of Maryland, Baltimore Potent d-peptide antagonists of mdm2 and mdmx for anticancer therapy
WO2014055039A1 (en) 2012-10-01 2014-04-10 Agency For Science, Technology And Research Peptides and methods for treating cancer
JP6568515B2 (ja) 2013-03-13 2019-08-28 プレジデント アンド フェローズ オブ ハーバード カレッジ ステープルドおよびステッチドポリペプチドならびにその使用
US20150010932A1 (en) * 2013-07-02 2015-01-08 Salk Institute For Biological Studies Methods for assaying protein-protein interactions

Similar Documents

Publication Publication Date Title
JP2018507689A5 (cg-RX-API-DMAC7.html)
US11814447B2 (en) Peptide ligands for binding to EphA2
CN112585156A (zh) 用于结合psma的肽配体
EP2035041B1 (en) Conjugates for innate immunotherapy of cancer
Glaffig et al. A fully synthetic glycopeptide antitumor vaccine based on multiple antigen presentation on a hyperbranched polymer
JP2019533475A5 (cg-RX-API-DMAC7.html)
JP2020502051A5 (cg-RX-API-DMAC7.html)
JP2015519339A5 (cg-RX-API-DMAC7.html)
CN107148425A (zh) 对mt1‑mmp特异性的双环肽配体
EP4055037A1 (en) Il-2r beta gamma c binding compounds
JP2014520120A5 (cg-RX-API-DMAC7.html)
KR101972012B1 (ko) 세포 투과성 스테이플 펩타이드, 이의 제조방법 및 그 용도
JP2014166186A5 (cg-RX-API-DMAC7.html)
KR20180042442A (ko) 방사성표지 her2 결합 펩티드
CN112585155A (zh) 用于结合il-17的肽配体
Pechar et al. The coiled coil motif in polymer drug delivery systems
CN104130315A (zh) 一种特异靶向her2蛋白的多肽
Hu et al. Targeted modification of the cationic anticancer peptide HPRP-A1 with iRGD to improve specificity, penetration, and tumor-tissue accumulation
CN105693860B (zh) 特异性靶向her2蛋白的多肽及其应用
CN105085632A (zh) 一种特异靶向egfr蛋白的多肽及其应用
CN111971060A (zh) 募集抗体并靶向肿瘤细胞的双功能分子
Nezir et al. Synthesis and evaluation of tumor-homing peptides for targeting prostate cancer
JP2015512247A5 (cg-RX-API-DMAC7.html)
US20250127887A1 (en) Self-Assembling Nanoparticles Based On Amphiphilic Peptides
CN105085631A (zh) 一种特异靶向her2蛋白的多肽及其应用