JP2018505205A5 - - Google Patents
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- Publication number
- JP2018505205A5 JP2018505205A5 JP2017542401A JP2017542401A JP2018505205A5 JP 2018505205 A5 JP2018505205 A5 JP 2018505205A5 JP 2017542401 A JP2017542401 A JP 2017542401A JP 2017542401 A JP2017542401 A JP 2017542401A JP 2018505205 A5 JP2018505205 A5 JP 2018505205A5
- Authority
- JP
- Japan
- Prior art keywords
- isolating
- pharmaceutically acceptable
- acceptable salt
- disorder
- mixing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WFVZVMGMPBTVBW-VYRBHSGPSA-N CC(C)(C)OC(N(CCC1)[C@@H]1C(c(cc1)c(CCO)cc1F)O)=O Chemical compound CC(C)(C)OC(N(CCC1)[C@@H]1C(c(cc1)c(CCO)cc1F)O)=O WFVZVMGMPBTVBW-VYRBHSGPSA-N 0.000 description 1
- WFVZVMGMPBTVBW-AAFJCEBUSA-N CC(C)(C)OC(N(CCC1)[C@H]1C(c(cc1)c(CCO)cc1F)O)=O Chemical compound CC(C)(C)OC(N(CCC1)[C@H]1C(c(cc1)c(CCO)cc1F)O)=O WFVZVMGMPBTVBW-AAFJCEBUSA-N 0.000 description 1
- MVUVVOWTNVWEFT-PZORYLMUSA-N [O-][NH+](CCC1)[C@H]1C1OCCc2c1ccc(F)c2 Chemical compound [O-][NH+](CCC1)[C@H]1C1OCCc2c1ccc(F)c2 MVUVVOWTNVWEFT-PZORYLMUSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562115064P | 2015-02-11 | 2015-02-11 | |
| US62/115,064 | 2015-02-11 | ||
| PCT/US2016/017539 WO2016130796A1 (en) | 2015-02-11 | 2016-02-11 | 1-heterocyclyl isochromanyl compounds and analogs for treating cns disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020018081A Division JP7023994B2 (ja) | 2015-02-11 | 2020-02-05 | Ｃｎｓ疾患を治療するための１－複素環イソクロマニル化合物およびアナログ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018505205A JP2018505205A (ja) | 2018-02-22 |
| JP2018505205A5 true JP2018505205A5 (https=) | 2019-03-22 |
| JP6657241B2 JP6657241B2 (ja) | 2020-03-04 |
Family
ID=55456908
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017542401A Expired - Fee Related JP6657241B2 (ja) | 2015-02-11 | 2016-02-11 | Ｃｎｓ疾患を治療するための１−複素環イソクロマニル化合物およびアナログ |
| JP2020018081A Expired - Fee Related JP7023994B2 (ja) | 2015-02-11 | 2020-02-05 | Ｃｎｓ疾患を治療するための１－複素環イソクロマニル化合物およびアナログ |
| JP2022018580A Pending JP2022065050A (ja) | 2015-02-11 | 2022-02-09 | Ｃｎｓ疾患を治療するための１－複素環イソクロマニル化合物およびアナログ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020018081A Expired - Fee Related JP7023994B2 (ja) | 2015-02-11 | 2020-02-05 | Ｃｎｓ疾患を治療するための１－複素環イソクロマニル化合物およびアナログ |
| JP2022018580A Pending JP2022065050A (ja) | 2015-02-11 | 2022-02-09 | Ｃｎｓ疾患を治療するための１－複素環イソクロマニル化合物およびアナログ |
Country Status (22)
| Country | Link |
|---|---|
| US (4) | US9856238B2 (https=) |
| EP (2) | EP4046995B1 (https=) |
| JP (3) | JP6657241B2 (https=) |
| KR (1) | KR102601972B1 (https=) |
| CN (2) | CN111925360B (https=) |
| AU (1) | AU2016219253C1 (https=) |
| CA (1) | CA2976095C (https=) |
| CY (1) | CY1125198T1 (https=) |
| DK (1) | DK3256466T3 (https=) |
| EA (1) | EA201791804A1 (https=) |
| ES (2) | ES2911910T3 (https=) |
| HU (1) | HUE058698T2 (https=) |
| IL (1) | IL253914B (https=) |
| MX (2) | MX371404B (https=) |
| MY (1) | MY188160A (https=) |
| NZ (1) | NZ735011A (https=) |
| PH (1) | PH12017501422A1 (https=) |
| PL (1) | PL3256466T3 (https=) |
| PT (1) | PT3256466T (https=) |
| SG (2) | SG11201706515QA (https=) |
| UA (1) | UA122222C2 (https=) |
| WO (1) | WO2016130796A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111171047B (zh) * | 2015-02-11 | 2023-06-23 | 赛诺维信制药公司 | 用于治疗cns障碍的稠合二氢-4h-吡唑并[5,1-c][1,4]噁嗪基化合物 |
| PL3256466T3 (pl) * | 2015-02-11 | 2022-05-23 | Sunovion Pharmaceuticals Inc. | Związki 1-heterocykliloizochromanylu i analogi do leczenia zaburzeń oun |
| UA125519C2 (uk) | 2016-07-29 | 2022-04-13 | Суновіон Фармасьютікалз Інк. | Сполуки і композиції і їх застосування |
| CA3032141A1 (en) | 2016-07-29 | 2018-02-01 | Vadim ALEXANDROV | Compounds and compositions and uses thereof |
| CN121221782A (zh) | 2017-06-30 | 2025-12-30 | 傲拓神经科学公司 | 用于治疗抑郁的nk-1拮抗剂组合物和方法 |
| BR112020001433A2 (pt) | 2017-08-02 | 2020-07-28 | Sunovion Pharmaceuticals Inc. | compostos de isocromano e usos dos mesmos |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| MX2021010880A (es) | 2019-03-14 | 2022-01-18 | Sunovion Pharmaceuticals Inc | Sales de un compuesto de isocromanilo y formas cristalinas, procesos de preparacion, usos terapeuticos y composiciones farmaceuticas de las mismas. |
| US12077546B2 (en) | 2021-04-10 | 2024-09-03 | Sumitomo Pharma Co., Ltd. | Bicyclic pyridine derivative |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3438995A (en) | 1968-01-08 | 1969-04-15 | Melville Sahyun | Diazaheterocyclic substituted benz-oxaheterocyclic compounds |
| US5621133A (en) | 1989-05-31 | 1997-04-15 | Deninno; Michael P. | Dopamine agonists |
| US4963568A (en) | 1989-05-31 | 1990-10-16 | Abbott Laboratories | Dopamine agonists |
| US5238939A (en) * | 1990-05-25 | 1993-08-24 | Akzo N.V. | Isochromane derivatives |
| IE73232B1 (en) * | 1990-05-25 | 1997-05-21 | Akzo Nv | Isochromane derivatives |
| JP2002519348A (ja) | 1998-06-30 | 2002-07-02 | イーライ・リリー・アンド・カンパニー | ５−ｈｔ１ｆアゴニスト |
| SE9902267D0 (sv) | 1999-06-16 | 1999-06-16 | Astra Ab | New compounds |
| CA2465186A1 (en) * | 2001-11-08 | 2003-05-15 | Sepracor, Inc. | Methods for treating depression and other cns disorders using enantiomerically enriched desmethyl- and didesmethyl-metabolites of citalopram |
| EP1831203A1 (en) * | 2004-12-21 | 2007-09-12 | F. Hoffmann-Roche AG | Chroman derivatives and uses thereof in the treatment of cns disorders |
| CN101203505A (zh) | 2005-04-22 | 2008-06-18 | 惠氏公司 | 苯并二氢吡喃和苯并吡喃衍生物及其用途 |
| AU2007209382A1 (en) * | 2006-01-27 | 2007-08-02 | F. Hoffmann-La Roche Ag | Use of 2-imidazoles for the treatment of CNS disorders |
| KR101103118B1 (ko) | 2007-11-02 | 2012-01-04 | 동아제약주식회사 | 신규한 1,3-디히드로-5-이소벤조퓨란카르보니트릴 유도체 화합물 및 이를 함유하는 조루증 치료용 약학조성물 |
| CN106883246B (zh) | 2009-12-04 | 2020-05-29 | 桑诺维恩药品公司 | 多环化合物及其使用方法 |
| JP5715713B2 (ja) | 2011-03-10 | 2015-05-13 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 可溶性グアニル酸シクラーゼ活性化因子 |
| AR090557A1 (es) | 2012-04-02 | 2014-11-19 | Orion Corp | DERIVADOS IMIDAZOLICOS AGONISTAS ADRENERGICOS a2 |
| EP2938341B1 (en) | 2012-12-31 | 2018-09-05 | Sunovion Pharmaceuticals Inc. | Heterocyclic compounds and methods of use thereof |
| PL3256466T3 (pl) * | 2015-02-11 | 2022-05-23 | Sunovion Pharmaceuticals Inc. | Związki 1-heterocykliloizochromanylu i analogi do leczenia zaburzeń oun |
-
2016
- 2016-02-11 PL PL16708262T patent/PL3256466T3/pl unknown
- 2016-02-11 MX MX2017010363A patent/MX371404B/es active IP Right Grant
- 2016-02-11 EA EA201791804A patent/EA201791804A1/ru unknown
- 2016-02-11 EP EP22166538.3A patent/EP4046995B1/en active Active
- 2016-02-11 MY MYPI2017702923A patent/MY188160A/en unknown
- 2016-02-11 NZ NZ735011A patent/NZ735011A/en not_active IP Right Cessation
- 2016-02-11 UA UAA201708945A patent/UA122222C2/uk unknown
- 2016-02-11 CA CA2976095A patent/CA2976095C/en active Active
- 2016-02-11 HU HUE16708262A patent/HUE058698T2/hu unknown
- 2016-02-11 ES ES16708262T patent/ES2911910T3/es active Active
- 2016-02-11 CN CN202010607608.6A patent/CN111925360B/zh not_active Expired - Fee Related
- 2016-02-11 ES ES22166538T patent/ES2967643T3/es active Active
- 2016-02-11 AU AU2016219253A patent/AU2016219253C1/en not_active Ceased
- 2016-02-11 JP JP2017542401A patent/JP6657241B2/ja not_active Expired - Fee Related
- 2016-02-11 KR KR1020177025290A patent/KR102601972B1/ko active Active
- 2016-02-11 DK DK16708262.7T patent/DK3256466T3/da active
- 2016-02-11 PT PT167082627T patent/PT3256466T/pt unknown
- 2016-02-11 CN CN201680018639.XA patent/CN107531674B/zh not_active Expired - Fee Related
- 2016-02-11 EP EP16708262.7A patent/EP3256466B9/en active Active
- 2016-02-11 SG SG11201706515QA patent/SG11201706515QA/en unknown
- 2016-02-11 MX MX2020001157A patent/MX392664B/es unknown
- 2016-02-11 US US15/041,852 patent/US9856238B2/en not_active Expired - Fee Related
- 2016-02-11 SG SG10201806809QA patent/SG10201806809QA/en unknown
- 2016-02-11 WO PCT/US2016/017539 patent/WO2016130796A1/en not_active Ceased
-
2017
- 2017-08-08 IL IL253914A patent/IL253914B/en unknown
- 2017-08-09 PH PH12017501422A patent/PH12017501422A1/en unknown
- 2017-11-21 US US15/819,372 patent/US10336732B2/en active Active
-
2019
- 2019-05-06 US US16/403,698 patent/US11192885B2/en not_active Expired - Fee Related
-
2020
- 2020-02-05 JP JP2020018081A patent/JP7023994B2/ja not_active Expired - Fee Related
-
2021
- 2021-10-29 US US17/452,786 patent/US20220185799A1/en not_active Abandoned
-
2022
- 2022-02-09 JP JP2022018580A patent/JP2022065050A/ja active Pending
- 2022-05-20 CY CY20221100352T patent/CY1125198T1/el unknown
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