JP2018504896A5 - - Google Patents

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Publication number
JP2018504896A5
JP2018504896A5 JP2017533828A JP2017533828A JP2018504896A5 JP 2018504896 A5 JP2018504896 A5 JP 2018504896A5 JP 2017533828 A JP2017533828 A JP 2017533828A JP 2017533828 A JP2017533828 A JP 2017533828A JP 2018504896 A5 JP2018504896 A5 JP 2018504896A5
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JP
Japan
Prior art keywords
item
peptide
nanoparticle
nanoparticles
molecule
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JP2017533828A
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English (en)
Japanese (ja)
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JP2018504896A (ja
JP6768664B2 (ja
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Priority claimed from PCT/EP2015/081197 external-priority patent/WO2016102687A1/en
Publication of JP2018504896A publication Critical patent/JP2018504896A/ja
Publication of JP2018504896A5 publication Critical patent/JP2018504896A5/ja
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JP2017533828A 2014-12-24 2015-12-23 分子の細胞内送達のためのペプチドおよびナノ粒子 Active JP6768664B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1403004 2014-12-24
FR14/03004 2014-12-24
PCT/EP2015/081197 WO2016102687A1 (en) 2014-12-24 2015-12-23 Peptides and nanoparticles for intracellular delivery of molecules

Publications (3)

Publication Number Publication Date
JP2018504896A JP2018504896A (ja) 2018-02-22
JP2018504896A5 true JP2018504896A5 (enExample) 2019-02-14
JP6768664B2 JP6768664B2 (ja) 2020-10-14

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ID=55174604

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JP2017533828A Active JP6768664B2 (ja) 2014-12-24 2015-12-23 分子の細胞内送達のためのペプチドおよびナノ粒子

Country Status (18)

Country Link
US (2) US10745440B2 (enExample)
EP (2) EP3237436B1 (enExample)
JP (1) JP6768664B2 (enExample)
CN (1) CN107548401A (enExample)
AU (1) AU2015370926B2 (enExample)
CA (1) CA2971643C (enExample)
CY (1) CY1121868T1 (enExample)
DK (1) DK3237436T3 (enExample)
ES (1) ES2743188T3 (enExample)
HR (1) HRP20191400T1 (enExample)
HU (1) HUE046054T2 (enExample)
IL (1) IL252810B (enExample)
LT (1) LT3237436T (enExample)
MX (1) MX387665B (enExample)
PL (1) PL3237436T3 (enExample)
PT (1) PT3237436T (enExample)
WO (1) WO2016102687A1 (enExample)
ZA (1) ZA201704364B (enExample)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
WO2014053879A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014053880A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
HRP20191400T1 (hr) 2014-12-24 2019-11-15 Aadigen Llc Peptidi i nanočestice za unutarstaničnu isporuku molekula
AU2017268842B2 (en) 2016-05-27 2022-08-11 Aadigen, Llc Peptides and nanoparticles for intracellular delivery of genome-editing molecules
CA3039797A1 (en) * 2016-10-11 2018-04-19 Minerva Biotechnologies Corporation Humanized anti-muc1* antibodies and use of cleavage enzyme
KR20190114966A (ko) 2016-12-09 2019-10-10 온키뮨 리미티드 조작된 자연 살해 세포 및 이의 용도
JP2020530463A (ja) * 2017-08-10 2020-10-22 アーディジェン, エルエルシー ウイルスの細胞内送達のためのペプチドおよびナノ粒子
CN109557067B (zh) * 2017-09-26 2021-07-20 中国科学院烟台海岸带研究所 一种核—卫星结构金纳米颗粒及其制备方法
WO2019079215A1 (en) * 2017-10-16 2019-04-25 Aadigen, Llc PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR MRRNA DELIVERY
CN108424437B (zh) * 2018-02-08 2021-06-22 青岛农业大学 一种递送分子及纳米颗粒、制备方法、用途
AU2019320494B2 (en) * 2018-08-07 2024-05-30 ETH Zürich Polypeptides self-assembling into nanoparticles
MX2021012740A (es) * 2019-04-17 2022-01-24 Aadigen Llc Péptidos y nanopartículas para entrega intracelular de moléculas.
KR102146392B1 (ko) * 2019-06-11 2020-08-21 한림대학교 산학협력단 포스포글리세레이트 뮤테이즈 1 융합단백질 및 이를 포함하는 약학 조성물
CN110540992B (zh) * 2019-08-21 2021-02-09 武汉泽智生物医药有限公司 增强靶基因沉默效率的siRNA分子及其应用
CN114786665A (zh) 2019-10-21 2022-07-22 新基公司 取代的4-氨基异二氢吲哚-1,3-二酮化合物和第二种活性剂的组合用途
CN111732635B (zh) * 2020-06-22 2022-03-22 中国医学科学院基础医学研究所 与cd123蛋白特异性结合的多肽、多肽复合物、共递送系统及其制备方法与应用
CA3190101A1 (en) 2020-07-24 2022-01-27 Aadigen, Llc Compositions and methods for treating viral infections
CN113563429A (zh) * 2021-07-19 2021-10-29 天津大学 一种基于烷基化多肽的核酸递送系统及制备方法与应用
WO2023215549A1 (en) * 2022-05-05 2023-11-09 Case Western Reserve University Immunostimulatory nanoparticle
WO2024155728A1 (en) * 2023-01-17 2024-07-25 Qana Therapeutics Inc. Nanoparticles and methods of use
WO2024187174A2 (en) 2023-03-09 2024-09-12 Aadigen, Llc Compositions for treating cancer with kras mutations and uses thereof
WO2025059215A1 (en) 2023-09-12 2025-03-20 Aadigen, Llc Methods and compositions for treating or preventing cancer
WO2025193628A2 (en) 2024-03-09 2025-09-18 Aadigen, Llc Compositions for treating cancer with kras mutations and uses thereof
WO2025193917A1 (en) * 2024-03-14 2025-09-18 Day Emily Antibody and sirna nanocarriers and uses thereof

Family Cites Families (21)

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EP0657039B1 (en) 1992-08-25 1998-12-16 MERCK PATENT GmbH Paper white pdlc system
US7514530B2 (en) 2004-04-26 2009-04-07 Centre National De La Recherche Scientifique Peptide carrier for delivering siRNA into mammalian cells
GB0513096D0 (en) 2005-06-28 2005-08-03 Strathclyde Treatment of microbial infections
EP1969000A2 (en) 2005-12-06 2008-09-17 Centre National de la Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
US7579318B2 (en) 2005-12-06 2009-08-25 Centre De La Recherche De La Scientifique Cell penetrating peptides for intracellular delivery of molecules
ATE490266T1 (de) 2005-12-06 2010-12-15 Centre Nat Rech Scient In zellen eindringende peptide als träger für moleküle
WO2008036929A2 (en) 2006-09-21 2008-03-27 Alnylam Pharmaceuticals, Inc. Complex for transferring an anionic substance into a cell
JP2011522796A (ja) 2008-05-06 2011-08-04 ニューヨーク ブラッド センター, インコーポレイテッド 抗ウイルス細胞透過性ペプチド
PL3006459T3 (pl) 2008-08-26 2022-01-17 City Of Hope Sposób i kompozycje dla wzmocnionego działania efektorowego komórek t przeciw guzowi nowotworowemu
WO2012137036A1 (en) 2011-04-04 2012-10-11 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
JP2015509085A (ja) * 2012-01-01 2015-03-26 キュービーアイ エンタープライゼズ リミテッドQbi Enterprises Ltd. 治療剤および診断剤の選択的送達のためのendo180を標的とする粒子
WO2013150338A1 (en) * 2012-04-04 2013-10-10 Centre National De La Recherche Scientifique Stapled cell penetrating peptides for intracellular delivery of molecules
WO2013154760A1 (en) 2012-04-11 2013-10-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric antigen receptors targeting b-cell maturation antigen
AU2013262972A1 (en) 2012-05-16 2014-12-11 Aadigen, Llc Multi-target modulation for treating fibrosis and inflammatory conditions
WO2014053882A1 (en) * 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014053880A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014053881A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014053879A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2014099671A1 (en) 2012-12-20 2014-06-26 Bluebird Bio, Inc. Chimeric antigen receptors and immune cells targeting b cell malignancies
LT2956175T (lt) 2013-02-15 2017-12-11 The Regents Of The University Of California Chimerinis antigeno receptorius ir jo panaudojimo būdai
HRP20191400T1 (hr) 2014-12-24 2019-11-15 Aadigen Llc Peptidi i nanočestice za unutarstaničnu isporuku molekula

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