JP2018502924A - 静脈内バクロフェン製剤および治療方法 - Google Patents

静脈内バクロフェン製剤および治療方法 Download PDF

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Publication number
JP2018502924A
JP2018502924A JP2017556780A JP2017556780A JP2018502924A JP 2018502924 A JP2018502924 A JP 2018502924A JP 2017556780 A JP2017556780 A JP 2017556780A JP 2017556780 A JP2017556780 A JP 2017556780A JP 2018502924 A JP2018502924 A JP 2018502924A
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Japan
Prior art keywords
baclofen
oral
administration
dose
solution
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JP2017556780A
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Japanese (ja)
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JP2018502924A5 (cg-RX-API-DMAC10.html
Inventor
クロイド ジム
クロイド ジム
ゴメツ アドルフォ
ゴメツ アドルフォ
クラッチ リンダ
クラッチ リンダ
クリエル ロバート
クリエル ロバート
シュロギー ジョン
シュロギー ジョン
タッカー ステファン
タッカー ステファン
テューイ ロブ
テューイ ロブ
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Allaysis LLC
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Allaysis LLC
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Publication of JP2018502924A publication Critical patent/JP2018502924A/ja
Publication of JP2018502924A5 publication Critical patent/JP2018502924A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017556780A 2015-01-15 2016-01-15 静脈内バクロフェン製剤および治療方法 Pending JP2018502924A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562103902P 2015-01-15 2015-01-15
US62/103,902 2015-01-15
PCT/US2016/013672 WO2016115504A1 (en) 2015-01-15 2016-01-15 Intravenous baclofen formulations and treatment methods

Publications (2)

Publication Number Publication Date
JP2018502924A true JP2018502924A (ja) 2018-02-01
JP2018502924A5 JP2018502924A5 (cg-RX-API-DMAC10.html) 2019-02-28

Family

ID=56406482

Family Applications (1)

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JP2017556780A Pending JP2018502924A (ja) 2015-01-15 2016-01-15 静脈内バクロフェン製剤および治療方法

Country Status (6)

Country Link
US (5) US10350183B2 (cg-RX-API-DMAC10.html)
EP (1) EP3244884A4 (cg-RX-API-DMAC10.html)
JP (1) JP2018502924A (cg-RX-API-DMAC10.html)
CA (1) CA2974091A1 (cg-RX-API-DMAC10.html)
MX (1) MX2017009313A (cg-RX-API-DMAC10.html)
WO (1) WO2016115504A1 (cg-RX-API-DMAC10.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023530769A (ja) * 2020-06-22 2023-07-19 オティビオ・エーエス 鎮痙組成物および陰圧療法を用いて痙縮を治療するための方法
JP2024501259A (ja) * 2020-12-24 2024-01-11 アレイシス、 エルエルシー 静脈内バクロフェンの投与方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3244884A4 (en) 2015-01-15 2018-07-25 Allaysis, LLC Intravenous baclofen formulations and treatment methods
RU2018118617A (ru) * 2015-10-21 2019-11-21 АЛЛЭЙСИС, ЭлЭлСи Баклофен для внутривенного введения и способы лечения

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010510314A (ja) * 2006-11-22 2010-04-02 シーサイド セラピューティクス，エルエルシー 精神遅滞、ダウン症候群、脆弱ｘ症候群および自閉症の治療方法
US20130109755A1 (en) * 2011-10-27 2013-05-02 Medtronic, Inc. Baclofen Formulations and Methods for Making Same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH26730A (en) 1988-12-30 1992-09-28 Ciba Geigy Ag Coated adhesive tablets
EP0461958B1 (fr) 1990-06-15 1994-09-14 Synthelabo Dérivés de 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxanes, leur préparation et leur application en thérapeutique
IT1319275B1 (it) * 1999-10-08 2003-09-26 Neuroscienze S C A R L Uso del baclofen nel trattamento dell'astinenza da etanolo.
US6969383B2 (en) 2002-09-27 2005-11-29 Medtronic, Inc. Method for treating severe tinnitus
US20060089335A1 (en) * 2003-10-14 2006-04-27 Guosong Liu Compositions and methods for enhancing cognitive function and synaptic plasticity
US7824697B2 (en) 2004-07-12 2010-11-02 Board Of Regents, The University Of Texas System High concentration baclofen preparations
CA2874737A1 (en) * 2012-06-01 2013-12-05 Lynn Health Science Institute, Inc. Use of baclofen to treat insomnia
EP3244884A4 (en) 2015-01-15 2018-07-25 Allaysis, LLC Intravenous baclofen formulations and treatment methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010510314A (ja) * 2006-11-22 2010-04-02 シーサイド セラピューティクス，エルエルシー 精神遅滞、ダウン症候群、脆弱ｘ症候群および自閉症の治療方法
US20130109755A1 (en) * 2011-10-27 2013-05-02 Medtronic, Inc. Baclofen Formulations and Methods for Making Same

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BRITISH JOURNAL OF NEUROSURGERY, vol. 22, JPN6019039784, 2008, pages 508 - 519, ISSN: 0004136144 *
JOURNAL OF PEDIATRIC REHABILITATION MEDICINE, vol. 4, JPN6019039781, 2011, pages 89 - 98, ISSN: 0004136143 *
JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 66, JPN6019039778, 2014, pages 935 - 942, ISSN: 0004262649 *
PHYSICAL MEDICINE AND REHABILITATION, vol. Vol.6(9S), JPN6019039777, 2014, pages 221 - 222, ISSN: 0004262648 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023530769A (ja) * 2020-06-22 2023-07-19 オティビオ・エーエス 鎮痙組成物および陰圧療法を用いて痙縮を治療するための方法
JP7586521B2 (ja) 2020-06-22 2024-11-19 オティビオ・エーエス 鎮痙組成物および陰圧療法を用いて痙縮を治療するための方法
JP2024501259A (ja) * 2020-12-24 2024-01-11 アレイシス、 エルエルシー 静脈内バクロフェンの投与方法

Also Published As

Publication number Publication date
US20200038353A1 (en) 2020-02-06
US20160213631A1 (en) 2016-07-28
US10933042B2 (en) 2021-03-02
US20230248679A1 (en) 2023-08-10
MX2017009313A (es) 2018-02-09
US10350183B2 (en) 2019-07-16
CA2974091A1 (en) 2016-07-21
US12295929B2 (en) 2025-05-13
US20190388373A1 (en) 2019-12-26
EP3244884A4 (en) 2018-07-25
EP3244884A1 (en) 2017-11-22
WO2016115504A1 (en) 2016-07-21
US20210228520A1 (en) 2021-07-29

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