IT1319275B1 - Uso del baclofen nel trattamento dell'astinenza da etanolo. - Google Patents

Uso del baclofen nel trattamento dell'astinenza da etanolo.

Info

Publication number
IT1319275B1
IT1319275B1 IT1999MI002107A ITMI992107A IT1319275B1 IT 1319275 B1 IT1319275 B1 IT 1319275B1 IT 1999MI002107 A IT1999MI002107 A IT 1999MI002107A IT MI992107 A ITMI992107 A IT MI992107A IT 1319275 B1 IT1319275 B1 IT 1319275B1
Authority
IT
Italy
Prior art keywords
baclofen
treatment
abstinence
ethanol
ethanol abstinence
Prior art date
Application number
IT1999MI002107A
Other languages
English (en)
Inventor
Gian Luigi Gessa
Giancarlo Colombo
Giovanni Addolorato
Original Assignee
Neuroscienze S C A R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroscienze S C A R L filed Critical Neuroscienze S C A R L
Publication of ITMI992107A0 publication Critical patent/ITMI992107A0/it
Priority to IT1999MI002107A priority Critical patent/IT1319275B1/it
Priority to DE60021590T priority patent/DE60021590T2/de
Priority to AU79146/00A priority patent/AU7914600A/en
Priority to PL354083A priority patent/PL200525B1/pl
Priority to DK00969423T priority patent/DK1217999T3/da
Priority to EP00969423A priority patent/EP1217999B1/en
Priority to PCT/EP2000/009750 priority patent/WO2001026638A2/en
Priority to AT00969423T priority patent/ATE300295T1/de
Priority to CA002386817A priority patent/CA2386817C/en
Priority to ES00969423T priority patent/ES2246900T3/es
Publication of ITMI992107A1 publication Critical patent/ITMI992107A1/it
Priority to HK02109321.9A priority patent/HK1048062A1/zh
Application granted granted Critical
Publication of IT1319275B1 publication Critical patent/IT1319275B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT1999MI002107A 1999-10-08 1999-10-08 Uso del baclofen nel trattamento dell'astinenza da etanolo. IT1319275B1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT1999MI002107A IT1319275B1 (it) 1999-10-08 1999-10-08 Uso del baclofen nel trattamento dell'astinenza da etanolo.
PCT/EP2000/009750 WO2001026638A2 (en) 1999-10-08 2000-10-05 The use of baclofen in the treatment of alcoholism
AU79146/00A AU7914600A (en) 1999-10-08 2000-10-05 The use of baclofen in the treatment of alcohol withdrawal syndrome and to promote alcohol abstinence in alcoholics
PL354083A PL200525B1 (pl) 1999-10-08 2000-10-05 Zastosowanie baklofenu do wytwarzania leku
DK00969423T DK1217999T3 (da) 1999-10-08 2000-10-05 Anvendelse af baclofen til behandling af alkoholisme
EP00969423A EP1217999B1 (en) 1999-10-08 2000-10-05 The use of baclofen in the treatment of alcoholism
DE60021590T DE60021590T2 (de) 1999-10-08 2000-10-05 Verwendung von baclofen zur behandlung von alkoholismus
AT00969423T ATE300295T1 (de) 1999-10-08 2000-10-05 Verwendung von baclofen zur behandlung von alkoholismus
CA002386817A CA2386817C (en) 1999-10-08 2000-10-05 The use of baclofen in the treatment of alcoholism
ES00969423T ES2246900T3 (es) 1999-10-08 2000-10-05 Uso de baclofeno en el tratamiento del alcoholismo.
HK02109321.9A HK1048062A1 (zh) 1999-10-08 2002-12-24 巴氯酚(baclofen)在酒精中毒治療中的應用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI002107A IT1319275B1 (it) 1999-10-08 1999-10-08 Uso del baclofen nel trattamento dell'astinenza da etanolo.

Publications (3)

Publication Number Publication Date
ITMI992107A0 ITMI992107A0 (it) 1999-10-08
ITMI992107A1 ITMI992107A1 (it) 2001-04-08
IT1319275B1 true IT1319275B1 (it) 2003-09-26

Family

ID=11383744

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI002107A IT1319275B1 (it) 1999-10-08 1999-10-08 Uso del baclofen nel trattamento dell'astinenza da etanolo.

Country Status (11)

Country Link
EP (1) EP1217999B1 (it)
AT (1) ATE300295T1 (it)
AU (1) AU7914600A (it)
CA (1) CA2386817C (it)
DE (1) DE60021590T2 (it)
DK (1) DK1217999T3 (it)
ES (1) ES2246900T3 (it)
HK (1) HK1048062A1 (it)
IT (1) IT1319275B1 (it)
PL (1) PL200525B1 (it)
WO (1) WO2001026638A2 (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
KR20110097942A (ko) 2003-08-20 2011-08-31 제노포트 인코포레이티드 아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법
US7494985B2 (en) 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
US7566738B2 (en) 2004-11-03 2009-07-28 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
WO2008033572A1 (en) 2006-09-15 2008-03-20 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
US7868043B2 (en) 2008-01-25 2011-01-11 Xenoport, Inc. Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
EP2250148B1 (en) 2008-01-25 2016-08-17 XenoPort, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use
CA2706575C (en) 2008-01-25 2015-07-14 Xenoport, Inc. Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs
WO2010017498A1 (en) 2008-08-07 2010-02-11 Xenoport, Inc. Methods of synthesizing n-hydroxysuccinimidyl carbonates
WO2010017504A1 (en) 2008-08-07 2010-02-11 Xenoport, Inc. Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
NZ594648A (en) 2009-03-03 2013-12-20 Xenoport Inc Sustained release oral dosage forms of an r-baclofen prodrug
WO2010120370A2 (en) 2009-04-17 2010-10-21 Xenoport, Inc. Gamma-amino-butyric acid derivatives as gabab receptor ligands
DE102010011069A1 (de) 2010-03-11 2011-09-15 Susanne Haamann Verfahren zur gezielten pharmakologischen und co-psychotherapeutischen Behandlung der Alkoholabhängigkeit mit Baclofen und Nalmefen
WO2013023155A1 (en) 2011-08-11 2013-02-14 Xenoport, Inc. Anhydrous and hemihydrate crystalline forms of an (r)-baclofen prodrug, methods of synthesis and methods of use
US10350183B2 (en) * 2015-01-15 2019-07-16 Allaysis, Llc Intravenous baclofen formulations and treatment methods

Also Published As

Publication number Publication date
PL200525B1 (pl) 2009-01-30
CA2386817A1 (en) 2001-04-19
DK1217999T3 (da) 2005-11-28
ITMI992107A1 (it) 2001-04-08
DE60021590D1 (de) 2005-09-01
WO2001026638A3 (en) 2002-02-28
DE60021590T2 (de) 2006-05-24
ES2246900T3 (es) 2006-03-01
PL354083A1 (en) 2003-12-29
AU7914600A (en) 2001-04-23
ITMI992107A0 (it) 1999-10-08
EP1217999B1 (en) 2005-07-27
ATE300295T1 (de) 2005-08-15
HK1048062A1 (zh) 2003-03-21
WO2001026638A2 (en) 2001-04-19
CA2386817C (en) 2009-05-12
EP1217999A2 (en) 2002-07-03

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