ATE300295T1 - Verwendung von baclofen zur behandlung von alkoholismus - Google Patents

Verwendung von baclofen zur behandlung von alkoholismus

Info

Publication number
ATE300295T1
ATE300295T1 AT00969423T AT00969423T ATE300295T1 AT E300295 T1 ATE300295 T1 AT E300295T1 AT 00969423 T AT00969423 T AT 00969423T AT 00969423 T AT00969423 T AT 00969423T AT E300295 T1 ATE300295 T1 AT E300295T1
Authority
AT
Austria
Prior art keywords
baclofen
treat alcoholism
alcoholism
treat
alcoholics
Prior art date
Application number
AT00969423T
Other languages
English (en)
Inventor
Gian Luigi Gessa
Giancarlo Colombo
Giovanni Addolorato
Original Assignee
Neuroscienze S C A R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroscienze S C A R L filed Critical Neuroscienze S C A R L
Application granted granted Critical
Publication of ATE300295T1 publication Critical patent/ATE300295T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT00969423T 1999-10-08 2000-10-05 Verwendung von baclofen zur behandlung von alkoholismus ATE300295T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI002107A IT1319275B1 (it) 1999-10-08 1999-10-08 Uso del baclofen nel trattamento dell'astinenza da etanolo.
PCT/EP2000/009750 WO2001026638A2 (en) 1999-10-08 2000-10-05 The use of baclofen in the treatment of alcoholism

Publications (1)

Publication Number Publication Date
ATE300295T1 true ATE300295T1 (de) 2005-08-15

Family

ID=11383744

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00969423T ATE300295T1 (de) 1999-10-08 2000-10-05 Verwendung von baclofen zur behandlung von alkoholismus

Country Status (11)

Country Link
EP (1) EP1217999B1 (de)
AT (1) ATE300295T1 (de)
AU (1) AU7914600A (de)
CA (1) CA2386817C (de)
DE (1) DE60021590T2 (de)
DK (1) DK1217999T3 (de)
ES (1) ES2246900T3 (de)
HK (1) HK1048062A1 (de)
IT (1) IT1319275B1 (de)
PL (1) PL200525B1 (de)
WO (1) WO2001026638A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
KR101140559B1 (ko) 2003-08-20 2012-07-05 제노포트 인코포레이티드 아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법
EP2354120A1 (de) 2003-08-20 2011-08-10 XenoPort, Inc. Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon
WO2006050471A2 (en) 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
WO2006050472A2 (en) 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids
WO2008033572A1 (en) 2006-09-15 2008-03-20 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
US7872046B2 (en) 2008-01-25 2011-01-18 Xenoport, Inc. Crystalline form of a (3S)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
JP5563483B2 (ja) 2008-01-25 2014-07-30 ゼノポート,インコーポレイティド アシロキシアルキルカルバメートプロドラッグの合成に使用されるアシロキシアルキルチオカーボネートの鏡像異性的な分解
WO2009094577A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
WO2010017498A1 (en) 2008-08-07 2010-02-11 Xenoport, Inc. Methods of synthesizing n-hydroxysuccinimidyl carbonates
US8299291B2 (en) 2008-08-07 2012-10-30 Xenoport, Inc. Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
CA2753057C (en) 2009-03-03 2018-09-11 Xenoport, Inc. Sustained release oral dosage forms of an r-baclofen prodrug
WO2010120370A2 (en) 2009-04-17 2010-10-21 Xenoport, Inc. Gamma-amino-butyric acid derivatives as gabab receptor ligands
DE102010011069A1 (de) 2010-03-11 2011-09-15 Susanne Haamann Verfahren zur gezielten pharmakologischen und co-psychotherapeutischen Behandlung der Alkoholabhängigkeit mit Baclofen und Nalmefen
WO2013023155A1 (en) 2011-08-11 2013-02-14 Xenoport, Inc. Anhydrous and hemihydrate crystalline forms of an (r)-baclofen prodrug, methods of synthesis and methods of use
US10350183B2 (en) * 2015-01-15 2019-07-16 Allaysis, Llc Intravenous baclofen formulations and treatment methods

Also Published As

Publication number Publication date
PL354083A1 (en) 2003-12-29
ITMI992107A0 (it) 1999-10-08
EP1217999A2 (de) 2002-07-03
WO2001026638A2 (en) 2001-04-19
AU7914600A (en) 2001-04-23
PL200525B1 (pl) 2009-01-30
WO2001026638A3 (en) 2002-02-28
HK1048062A1 (zh) 2003-03-21
DE60021590T2 (de) 2006-05-24
DK1217999T3 (da) 2005-11-28
CA2386817C (en) 2009-05-12
DE60021590D1 (de) 2005-09-01
ES2246900T3 (es) 2006-03-01
IT1319275B1 (it) 2003-09-26
ITMI992107A1 (it) 2001-04-08
EP1217999B1 (de) 2005-07-27
CA2386817A1 (en) 2001-04-19

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