DE60021590D1 - Verwendung von baclofen zur behandlung von alkoholismus - Google Patents

Verwendung von baclofen zur behandlung von alkoholismus

Info

Publication number
DE60021590D1
DE60021590D1 DE60021590T DE60021590T DE60021590D1 DE 60021590 D1 DE60021590 D1 DE 60021590D1 DE 60021590 T DE60021590 T DE 60021590T DE 60021590 T DE60021590 T DE 60021590T DE 60021590 D1 DE60021590 D1 DE 60021590D1
Authority
DE
Germany
Prior art keywords
baclofen
treatment
alcoholism
alcoholics
abstinence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60021590T
Other languages
English (en)
Other versions
DE60021590T2 (de
Inventor
Luigi Gessa
Giancarlo Colombo
Giovanni Addolorato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neuroscienze SCARL
Original Assignee
Neuroscienze SCARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroscienze SCARL filed Critical Neuroscienze SCARL
Application granted granted Critical
Publication of DE60021590D1 publication Critical patent/DE60021590D1/de
Publication of DE60021590T2 publication Critical patent/DE60021590T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Addiction (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE60021590T 1999-10-08 2000-10-05 Verwendung von baclofen zur behandlung von alkoholismus Expired - Lifetime DE60021590T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999MI002107A IT1319275B1 (it) 1999-10-08 1999-10-08 Uso del baclofen nel trattamento dell'astinenza da etanolo.
ITMI992107 1999-10-08
PCT/EP2000/009750 WO2001026638A2 (en) 1999-10-08 2000-10-05 The use of baclofen in the treatment of alcoholism

Publications (2)

Publication Number Publication Date
DE60021590D1 true DE60021590D1 (de) 2005-09-01
DE60021590T2 DE60021590T2 (de) 2006-05-24

Family

ID=11383744

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60021590T Expired - Lifetime DE60021590T2 (de) 1999-10-08 2000-10-05 Verwendung von baclofen zur behandlung von alkoholismus

Country Status (11)

Country Link
EP (1) EP1217999B1 (de)
AT (1) ATE300295T1 (de)
AU (1) AU7914600A (de)
CA (1) CA2386817C (de)
DE (1) DE60021590T2 (de)
DK (1) DK1217999T3 (de)
ES (1) ES2246900T3 (de)
HK (1) HK1048062A1 (de)
IT (1) IT1319275B1 (de)
PL (1) PL200525B1 (de)
WO (1) WO2001026638A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
EP2354120A1 (de) 2003-08-20 2011-08-10 XenoPort, Inc. Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon
BRPI0413756A (pt) 2003-08-20 2006-10-31 Xenoport Inc composto, métodos para tratar ou evitar espasticidade ou um sintoma de espasticidade, doença de refluxo gastro-esofágico, vìcio em droga, vìcio em ou abuso de álcool, ou vìcio em ou abuso de nicotina, e tosse ou êmese em um paciente, e, composição farmacêutica
WO2006050472A2 (en) 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids
WO2006050471A2 (en) 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
WO2008033572A1 (en) 2006-09-15 2008-03-20 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
WO2009094569A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
WO2009094563A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-b-methyl-hexanoic acids and methods of use
WO2009094577A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
US8299291B2 (en) 2008-08-07 2012-10-30 Xenoport, Inc. Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
US7989641B2 (en) 2008-08-07 2011-08-02 Xenoport, Inc. Methods of synthesizing N-hydroxysuccinimidyl carbonates
EP2403486A1 (de) 2009-03-03 2012-01-11 XenoPort, Inc. Orale dosierformen eines r-baclofen-prodrugs mit verzögerter freisetzung
US8344028B2 (en) 2009-04-17 2013-01-01 Xenoport, Inc. Gamma-amino-butyric acid derivatives as GABAB receptor ligands
DE102010011069A1 (de) 2010-03-11 2011-09-15 Susanne Haamann Verfahren zur gezielten pharmakologischen und co-psychotherapeutischen Behandlung der Alkoholabhängigkeit mit Baclofen und Nalmefen
WO2013023155A1 (en) 2011-08-11 2013-02-14 Xenoport, Inc. Anhydrous and hemihydrate crystalline forms of an (r)-baclofen prodrug, methods of synthesis and methods of use
US10350183B2 (en) * 2015-01-15 2019-07-16 Allaysis, Llc Intravenous baclofen formulations and treatment methods

Also Published As

Publication number Publication date
EP1217999A2 (de) 2002-07-03
PL200525B1 (pl) 2009-01-30
PL354083A1 (en) 2003-12-29
DK1217999T3 (da) 2005-11-28
WO2001026638A2 (en) 2001-04-19
CA2386817C (en) 2009-05-12
AU7914600A (en) 2001-04-23
ATE300295T1 (de) 2005-08-15
HK1048062A1 (zh) 2003-03-21
CA2386817A1 (en) 2001-04-19
DE60021590T2 (de) 2006-05-24
EP1217999B1 (de) 2005-07-27
ITMI992107A1 (it) 2001-04-08
WO2001026638A3 (en) 2002-02-28
ES2246900T3 (es) 2006-03-01
ITMI992107A0 (it) 1999-10-08
IT1319275B1 (it) 2003-09-26

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Legal Events

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