JP2018501201A5 - - Google Patents

Download PDF

Info

Publication number
JP2018501201A5
JP2018501201A5 JP2017526674A JP2017526674A JP2018501201A5 JP 2018501201 A5 JP2018501201 A5 JP 2018501201A5 JP 2017526674 A JP2017526674 A JP 2017526674A JP 2017526674 A JP2017526674 A JP 2017526674A JP 2018501201 A5 JP2018501201 A5 JP 2018501201A5
Authority
JP
Japan
Prior art keywords
seq
polypeptide
amino acid
acid sequence
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017526674A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018501201A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/061118 external-priority patent/WO2016081475A1/en
Publication of JP2018501201A publication Critical patent/JP2018501201A/ja
Publication of JP2018501201A5 publication Critical patent/JP2018501201A5/ja
Pending legal-status Critical Current

Links

JP2017526674A 2014-11-17 2015-11-17 異常な線維芽細胞増殖および細胞外マトリックス沈着を特徴とする疾患、状態、またはプロセスを予防または処置するための組成物および方法 Pending JP2018501201A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462080784P 2014-11-17 2014-11-17
US62/080,784 2014-11-17
US14/943,752 2015-11-17
PCT/US2015/061118 WO2016081475A1 (en) 2014-11-17 2015-11-17 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
US14/943,752 US10500249B2 (en) 2014-11-17 2015-11-17 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition

Publications (2)

Publication Number Publication Date
JP2018501201A JP2018501201A (ja) 2018-01-18
JP2018501201A5 true JP2018501201A5 (https=) 2018-12-27

Family

ID=55960752

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017526674A Pending JP2018501201A (ja) 2014-11-17 2015-11-17 異常な線維芽細胞増殖および細胞外マトリックス沈着を特徴とする疾患、状態、またはプロセスを予防または処置するための組成物および方法

Country Status (13)

Country Link
US (1) US10500249B2 (https=)
EP (1) EP3220943A4 (https=)
JP (1) JP2018501201A (https=)
KR (1) KR20170083063A (https=)
CN (1) CN107106650A (https=)
AU (1) AU2015350151A1 (https=)
BR (1) BR112017010238A2 (https=)
CA (1) CA2967621A1 (https=)
MX (1) MX2017006372A (https=)
RU (1) RU2017121090A (https=)
SG (1) SG11201703939XA (https=)
WO (1) WO2016081475A1 (https=)
ZA (1) ZA201703305B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020002206A (es) * 2017-09-08 2020-07-20 Bristol Myers Squibb Co Factor de crecimiento de fibroblastos 21 (fgf-21) modificado para usarse en metodos para tratar la esteatohepatitis no alcoholica (nash).
US11725056B2 (en) 2017-10-03 2023-08-15 Cedars-Sinai Medical Center Methods for targeting the immune checkpoint PD1 pathway for treating pulmonary fibrosis
CN108795935B (zh) * 2018-05-23 2022-06-21 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 日本血吸虫SjELAV-like 1基因的siRNA及其应用
CN110575540B (zh) * 2018-06-07 2021-11-02 中山大学附属第六医院 Pdgf抑制剂用于制备治疗肠道炎症疾病的药物方面的用途
CN113134116B (zh) * 2020-01-20 2022-09-06 山东威高宏瑞医学科技有限公司 内镜微创手术用的填充组合物及填充制剂
CN113952821A (zh) * 2021-07-22 2022-01-21 上海安居乐环保科技股份有限公司 一种罐区装卸区废气综合治理方法及系统
CN113730551B (zh) * 2021-09-02 2022-11-25 徐州医科大学 Mmi-0100短肽化合物在制备胆汁淤积性肝病治疗药物中的应用
CN118388635B (zh) * 2024-06-24 2024-10-11 山东美瑞生物技术有限公司 一种提高皮肤修复功能的重组人源化胶原蛋白的制备方法
CN118571492B (zh) * 2024-08-02 2024-10-18 天津市胸科医院 基于组织边界影响的主动脉夹层患者并发症风险预测模型

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521000A (en) 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
US4227522A (en) 1978-09-05 1980-10-14 Syntex Puerto Rico, Inc. Inhalation device
US4192309A (en) 1978-09-05 1980-03-11 Syntex Puerto Rico, Inc. Inhalation device with capsule opener
DK172541B1 (da) 1982-10-08 1998-12-07 Glaxo Group Ltd Apparat til administrering af medikamenter til patienter og en medikamentpakning til brug i apparatet
US4778054A (en) 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
DE3682457D1 (de) 1985-07-30 1991-12-19 Glaxo Group Ltd Geraet zur verabreichung von medikamenten an patienten.
JPH05963A (ja) 1990-04-13 1993-01-08 Toray Ind Inc ポリペプチド類組成物
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5352461A (en) 1992-03-11 1994-10-04 Pharmaceutical Discovery Corporation Self assembling diketopiperazine drug delivery system
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
EP0733059B1 (en) 1993-12-09 2000-09-13 Thomas Jefferson University Compounds and methods for site-directed mutations in eukaryotic cells
US6428771B1 (en) 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
ES2261195T3 (es) 1999-04-05 2006-11-16 Mannkind Corporation Metodo de formacion de particulas finas.
ES2569916T3 (es) 1999-06-29 2016-05-13 Mannkind Corporation Formulaciones farmacéuticas que comprenden insulina complejada con una dicetopiperazina
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
CN101014321A (zh) 2004-08-23 2007-08-08 曼金德公司 5型磷酸二酯酶抑制剂的肺部给予
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
DK2617431T3 (en) * 2007-01-10 2017-07-10 Purdue Research Foundation Polypeptide inhibitors of HSP27 kinase and applications therefor
NL1033850C2 (nl) 2007-05-15 2008-11-18 3Force B V Brandersysteem met voorgemengde branders en vlam-overdrachtsmiddelen.
WO2009021137A2 (en) 2007-08-07 2009-02-12 Purdue Research Foundation Kinase inhibitors and uses thereof
CN102256613B (zh) * 2008-10-20 2014-09-10 莫伊莱麦屈克斯公司 用于治疗或者预防粘连的多肽
EP2378875B1 (en) * 2008-12-10 2018-05-30 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
US20130115256A1 (en) * 2010-05-24 2013-05-09 Cynthia Lander Methods for treating or preventing vascular graft failure
KR101862291B1 (ko) 2011-04-12 2018-05-29 모레 매트릭스 인코포레이티드 이상 섬유모세포 증식 및 세포외 기질 침착을 특징으로 하는 질병, 질환, 또는 과정을 예방하거나 치료하기 위한 조성물 및 방법
WO2013134636A1 (en) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
EP2931272A1 (en) * 2012-12-12 2015-10-21 The Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Healthcare System Methods of treating hepatic fibrosis and associated diseases by regulating rev-erb activity

Similar Documents

Publication Publication Date Title
JP2018501201A5 (https=)
RU2017121090A (ru) Композиции и способы для профилактики или лечения заболеваний, состояний или процессов, характеризующихся аберрантной пролиферацией фибробластов и накоплением внеклеточного матрикса
JP2014533235A5 (https=)
Van Dijk et al. Targeted therapies in liver fibrosis: combining the best parts of platelet-derived growth factor BB and interferon gamma
JP6355032B2 (ja) 新規組換え二機能性融合タンパク質、それらの調製および使用
JP2023025005A (ja) 疾患の治療または予防に用いるためのファクター1およびファクター2タンパク質、およびその阻害剤
JP2020121984A (ja) 抗vegf抗体での治療
EP2170366B1 (en) Use of tlr-2 antagonists for treatment of reperfusion injury and tissue damage
O'Brien et al. Evaluation of merocyanine 540-sensitized photoirradiation as a means to inactivate enveloped viruses in blood products
CN108136025A (zh) 一种使用免疫调节治疗癌症的新颖方法
US20090263389A1 (en) Use of TGF-Beta Antagonists to Treat or to Prevent Chronic Transplant Rejection
RU2013150249A (ru) Композиции и способы профилактики или лечения заболеваний, состояний или процессов, характеризуемых аберрантной пролиферацией фибробластов и отложением внеклеточного матрикса
AU2019366366B2 (en) Therapeutic combinations of TDFRPs and additional agents and methods of use
KR20170029576A (ko) 골형성단백질의 치료적 용도
US20040266687A1 (en) Compositions and methods comprising protein activated receptor antagonists
KR20160093076A (ko) 암의 치료용 조합 제조물
KR20220015375A (ko) Sephb4-hsa 융합 단백질을 이용한 암의 치료
Zhao et al. Inhibition of tumor angiogenesis and tumor growth by the DSL domain of human Delta-like 1 targeted to vascular endothelial cells
WO2012118042A1 (ja) 悪性腫瘍転移抑制用医薬
JP2017509633A5 (https=)
EP3920961A2 (en) Growth hormone-releasing hormone antagonists and uses thereof
Ellmers et al. (Pro) renin receptor blockade ameliorates cardiac injury and remodeling and improves function after myocardial infarction
US11571455B2 (en) Methods and compositions for treating alcoholic liver disease
JP7182793B2 (ja) 病理学的腎組織損傷を予防及び治療するための方法
JP6782932B2 (ja) Npr−aアゴニストの新規用途