JP2018500352A5 - - Google Patents
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- Publication number
- JP2018500352A5 JP2018500352A5 JP2017533929A JP2017533929A JP2018500352A5 JP 2018500352 A5 JP2018500352 A5 JP 2018500352A5 JP 2017533929 A JP2017533929 A JP 2017533929A JP 2017533929 A JP2017533929 A JP 2017533929A JP 2018500352 A5 JP2018500352 A5 JP 2018500352A5
- Authority
- JP
- Japan
- Prior art keywords
- diverse collection
- cyclic peptide
- bacteriophage particles
- bacteriophage
- desired properties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000001189 Cyclic Peptides Human genes 0.000 claims 5
- 108010069514 Cyclic Peptides Proteins 0.000 claims 5
- 239000002245 particle Substances 0.000 claims 4
- 241001515965 unidentified phage Species 0.000 claims 4
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14199588 | 2014-12-22 | ||
| EP14199588.6 | 2014-12-22 | ||
| PCT/EP2015/080738 WO2016102434A1 (en) | 2014-12-22 | 2015-12-21 | Novel methods for displaying cyclic peptides on bacteriophage particles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018500352A JP2018500352A (ja) | 2018-01-11 |
| JP2018500352A5 true JP2018500352A5 (https=) | 2018-09-13 |
| JP6810041B2 JP6810041B2 (ja) | 2021-01-06 |
Family
ID=52292661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533929A Expired - Fee Related JP6810041B2 (ja) | 2014-12-22 | 2015-12-21 | バクテリオファージ粒子上に環状ペプチドを提示する新規の方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10774323B2 (https=) |
| EP (1) | EP3237614B1 (https=) |
| JP (1) | JP6810041B2 (https=) |
| KR (1) | KR20170090509A (https=) |
| CN (1) | CN107109403A (https=) |
| AU (1) | AU2015371172B2 (https=) |
| CA (1) | CA2971672A1 (https=) |
| DK (1) | DK3237614T3 (https=) |
| MX (1) | MX2017008286A (https=) |
| RU (1) | RU2702087C2 (https=) |
| WO (1) | WO2016102434A1 (https=) |
| ZA (1) | ZA201704674B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2603586B2 (en) | 2010-08-13 | 2025-02-26 | Miti Biosystems GmbH | Modified peptide display |
| CN106366168B (zh) * | 2016-08-26 | 2020-09-15 | 上海交通大学 | 羊毛硫肽类抗菌肽及其脱氢衍生物的制备方法 |
| CN109432399A (zh) * | 2018-12-27 | 2019-03-08 | 重庆市科学技术研究院 | 用于乙型肝炎的环肽药物及其应用 |
| CN113727725A (zh) * | 2019-05-20 | 2021-11-30 | 得克萨斯A&M大学系统 | 遗传编码的噬菌体展示的环状肽文库及其制备方法 |
| US20230304025A1 (en) * | 2020-07-20 | 2023-09-28 | Massachusetts Institute Of Technology | M13 bacteriophage with a high cysteine content and genetically engineerable hydrogels |
| CN112851788B (zh) * | 2021-02-03 | 2022-11-01 | 河北省科学院生物研究所 | 一种羊毛硫肽LichencinA3及其制备方法和应用 |
| PL443378A1 (pl) * | 2022-12-31 | 2024-07-01 | Instytut Biotechnologii I Medycyny Molekularnej | 7 aminokwasowe sekwencje oraz klony fagowe wiążące selektywnie jony niklu |
| CN116790698B (zh) * | 2023-06-21 | 2024-06-18 | 南京大学 | 基于氧化脱羧酶的硫醛合成方法及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3852304T3 (de) | 1987-03-02 | 1999-07-01 | Enzon Labs Inc., Piscataway, N.J. | Organismus als Träger für "Single Chain Antibody Domain (SCAD)". |
| EP0436597B1 (en) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US6660843B1 (en) * | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| CA2376232A1 (en) | 1999-06-14 | 2000-12-21 | Genentech, Inc. | A structured peptide scaffold for displaying turn libraries on phage |
| US7785825B2 (en) * | 2004-01-12 | 2010-08-31 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for dehydration and cyclization of peptides, synthetic compounds, and lantibiotics |
| CN101115838B (zh) | 2004-12-07 | 2015-08-12 | 莫菲西斯公司 | 产生和分泌修饰的肽的方法 |
| US8367588B2 (en) * | 2005-10-12 | 2013-02-05 | The Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
| AU2009211253B2 (en) | 2008-02-05 | 2014-11-06 | Bicyclerd Limited | Methods and compositions |
| EP2405008A1 (en) * | 2010-07-06 | 2012-01-11 | LanthioPep B.V. | Bacterial surface display of thioether-bridge-containing peptides |
| EP2603586B2 (en) * | 2010-08-13 | 2025-02-26 | Miti Biosystems GmbH | Modified peptide display |
| EP2578599A1 (en) | 2011-10-07 | 2013-04-10 | LanthioPep B.V. | Cyclic analogs of GLP-1 and GLP-1 related peptides |
| CA2961285A1 (en) * | 2014-09-26 | 2016-03-31 | The Board Of Trustees Of The University Of Illinois | Biosynthesis and engineering of lanthipeptides |
-
2015
- 2015-12-21 DK DK15817300.5T patent/DK3237614T3/da active
- 2015-12-21 AU AU2015371172A patent/AU2015371172B2/en not_active Ceased
- 2015-12-21 JP JP2017533929A patent/JP6810041B2/ja not_active Expired - Fee Related
- 2015-12-21 EP EP15817300.5A patent/EP3237614B1/en not_active Not-in-force
- 2015-12-21 RU RU2017122176A patent/RU2702087C2/ru active
- 2015-12-21 WO PCT/EP2015/080738 patent/WO2016102434A1/en not_active Ceased
- 2015-12-21 US US15/537,910 patent/US10774323B2/en not_active Expired - Fee Related
- 2015-12-21 CN CN201580069979.0A patent/CN107109403A/zh active Pending
- 2015-12-21 MX MX2017008286A patent/MX2017008286A/es unknown
- 2015-12-21 KR KR1020177020523A patent/KR20170090509A/ko not_active Ceased
- 2015-12-21 CA CA2971672A patent/CA2971672A1/en active Pending
-
2017
- 2017-07-11 ZA ZA2017/04674A patent/ZA201704674B/en unknown
-
2020
- 2020-08-12 US US16/991,694 patent/US20200385705A1/en not_active Abandoned
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