JP2018197240A5 - - Google Patents
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- JP2018197240A5 JP2018197240A5 JP2018131875A JP2018131875A JP2018197240A5 JP 2018197240 A5 JP2018197240 A5 JP 2018197240A5 JP 2018131875 A JP2018131875 A JP 2018131875A JP 2018131875 A JP2018131875 A JP 2018131875A JP 2018197240 A5 JP2018197240 A5 JP 2018197240A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- oral pharmaceutical
- composition according
- oil
- liquid formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IL2013/050007 WO2013102899A1 (en) | 2012-01-03 | 2013-01-03 | Methods and compositions for treating diabetes |
| ILPCT/IL2013/050007 | 2013-01-03 | ||
| US201361763996P | 2013-02-13 | 2013-02-13 | |
| US61/763,996 | 2013-02-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015551250A Division JP2016505613A (ja) | 2013-01-03 | 2014-01-02 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020102461A Division JP2020180126A (ja) | 2013-01-03 | 2020-06-12 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018197240A JP2018197240A (ja) | 2018-12-13 |
| JP2018197240A5 true JP2018197240A5 (enExample) | 2019-01-31 |
Family
ID=51062529
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015551250A Pending JP2016505613A (ja) | 2013-01-03 | 2014-01-02 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
| JP2018131875A Pending JP2018197240A (ja) | 2013-01-03 | 2018-07-11 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
| JP2020102461A Pending JP2020180126A (ja) | 2013-01-03 | 2020-06-12 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
| JP2022156787A Pending JP2023002570A (ja) | 2013-01-03 | 2022-09-29 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
| JP2025040577A Pending JP2025106279A (ja) | 2013-01-03 | 2025-03-13 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015551250A Pending JP2016505613A (ja) | 2013-01-03 | 2014-01-02 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020102461A Pending JP2020180126A (ja) | 2013-01-03 | 2020-06-12 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
| JP2022156787A Pending JP2023002570A (ja) | 2013-01-03 | 2022-09-29 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
| JP2025040577A Pending JP2025106279A (ja) | 2013-01-03 | 2025-03-13 | Nafld、脂肪肝、および、その後遺症を処置するための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US20150335715A1 (enExample) |
| EP (2) | EP4215205A1 (enExample) |
| JP (5) | JP2016505613A (enExample) |
| CN (2) | CN104902921A (enExample) |
| WO (1) | WO2014106846A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2722054B1 (en) * | 2005-09-06 | 2018-03-21 | Oramed Pharmaceuticals Inc. | Methods and compositions for oral administration of proteins |
| RU2504373C2 (ru) | 2008-03-26 | 2014-01-20 | ОРАМЕД Лтд. | Способы и композиции для перорального введения протеинов |
| CA2723434C (en) | 2008-05-05 | 2018-01-23 | Oramed Ltd. | Methods and compositions for oral administration of exenatide |
| WO2013102899A1 (en) | 2012-01-03 | 2013-07-11 | Oramed Ltd. | Methods and compositions for treating diabetes |
| ES2912138T3 (es) | 2012-02-01 | 2022-05-24 | Oramed Ltd | Composiciones que contienen inhibidores de proteasa, composiciones que comprenden las mismas y métodos para producir y usar las misma |
| CN104902921A (zh) | 2013-01-03 | 2015-09-09 | 奥拉姆德有限公司 | 用于治疗nafld、肝性脂肪变性及其后遗症的方法和组合物 |
| BR112015022762B1 (pt) | 2013-03-13 | 2022-08-16 | Takeda Pharmaceutical Company Limited | Composto de éster do ácido guanidinobenzóico, composição farmacêutica, e, uso do composto |
| US9428470B2 (en) | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| US9346776B2 (en) | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
| US10980866B2 (en) * | 2014-09-22 | 2021-04-20 | Hadasit Medical Research Services And Development Ltd. | Alpha-1 anti-trypsin for treating liver diseases |
| KR102399254B1 (ko) * | 2016-09-28 | 2022-05-17 | 아이거 바이오파마슈티컬스 인코포레이티드 | 비-알코올성 지방간염의 치료를 위한 방법 및 약제학적 조성물 |
| CN109806386A (zh) * | 2017-11-20 | 2019-05-28 | 江苏恒瑞医药股份有限公司 | Fxr激动剂与glp-1类似物的药物组合物和用途 |
| MX2020013296A (es) * | 2018-06-11 | 2021-05-27 | Oramed Ltd | Composiciones que contienen inhibidor de proteasa recombinante, metodos para producir las mismas y usos de las mismas. |
| WO2021142736A1 (en) * | 2020-01-16 | 2021-07-22 | Shanghai Benemae Pharmaceutical Corporation | Dosing regimen of glp-1 |
| WO2021142733A1 (en) | 2020-01-16 | 2021-07-22 | Shanghai Benemae Pharmaceutical Corporation | Combinational therapy comprising glp-1 and/or glp-1 analogs, and insulin and/or insulin analogs |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL68769A (en) | 1983-05-23 | 1986-02-28 | Hadassah Med Org | Pharmaceutical compositions containing insulin for oral administration |
| JPS6350793A (ja) | 1986-08-20 | 1988-03-03 | 株式会社東芝 | 高速増殖炉の崩壊熱除去システム |
| US5034415A (en) | 1987-08-07 | 1991-07-23 | Century Laboratories, Inc. | Treatment of diabetes mellitus |
| EP0351651B1 (en) | 1988-07-21 | 1993-09-15 | F. Hoffmann-La Roche Ag | Insulin preparation |
| JPH02250823A (ja) | 1989-03-24 | 1990-10-08 | Tsumura & Co | マイクロカプセル剤およびその製造方法 |
| GB9007052D0 (en) | 1990-03-29 | 1990-05-30 | Skua Investments Ltd | Pharmaceutical formulations |
| US5206219A (en) | 1991-11-25 | 1993-04-27 | Applied Analytical Industries, Inc. | Oral compositions of proteinaceous medicaments |
| DE69333025T2 (de) * | 1992-11-17 | 2004-04-29 | E.I. Du Pont De Nemours And Co., Wilmington | Für mikrosom delta 12 fettsäuredesaturase kodierende gene und verwandte enzyme von pflanzen |
| US6692766B1 (en) | 1994-06-15 | 2004-02-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Controlled release oral drug delivery system |
| US5824638A (en) | 1995-05-22 | 1998-10-20 | Shire Laboratories, Inc. | Oral insulin delivery |
| IL114673A (en) | 1995-07-19 | 2000-12-06 | Hadasit Med Res Service | Pharmaceutical compositions containing protein for oral administration |
| JPH09208485A (ja) | 1996-01-31 | 1997-08-12 | Teijin Ltd | ペプチド・蛋白質性薬物の水難溶性組成物 |
| DE69740096D1 (de) | 1996-08-08 | 2011-02-17 | Amylin Pharmaceuticals Inc | Pharmazeutische Zusammensetzung mit einem Exendin-4-Peptid |
| JPH10330287A (ja) | 1997-03-31 | 1998-12-15 | Nippon Suisan Kaisha Ltd | 多価不飽和脂肪酸からなる消化管吸収促進剤およびそれを含有する薬剤 |
| JP2000128805A (ja) | 1998-10-27 | 2000-05-09 | Nippon Suisan Kaisha Ltd | 多価不飽和脂肪酸および高分子ゲルからなる経粘膜吸収促進剤及びそれを含有する薬剤 |
| US6761903B2 (en) | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
| CZ305123B6 (cs) * | 1999-10-04 | 2015-05-13 | Novartis Vaccines And Diagnostics, Inc. | Způsob výroby kapalného farmaceutického prostředku |
| JP2001240558A (ja) | 2000-02-29 | 2001-09-04 | Nippon Suisan Kaisha Ltd | 多価不飽和脂肪酸を経粘膜吸収促進剤として含有する固形製剤。 |
| US6673574B2 (en) | 2000-11-30 | 2004-01-06 | Unigene Laboratories Inc. | Oral delivery of peptides using enzyme-cleavable membrane translocators |
| KR20010069322A (ko) | 2001-03-08 | 2001-07-25 | 서종수 | 휴대형정보단말기 또는 화상이동통신장치를 이용한전자경매방법 |
| KR20010069433A (ko) | 2001-03-22 | 2001-07-25 | 김윤완 | 노루궁뎅이버섯을 이용한 건강 보조 식품 |
| CN1160122C (zh) | 2001-04-20 | 2004-08-04 | 清华大学 | 一种制备口服胰岛素油相制剂的方法 |
| CN1741805A (zh) | 2001-07-18 | 2006-03-01 | 索莱有限责任公司 | 高蛋白质鲍曼-比尔克抑制剂浓缩物及其生产方法 |
| US20030198666A1 (en) | 2002-01-07 | 2003-10-23 | Richat Abbas | Oral insulin therapy |
| US7767828B2 (en) | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US20060286129A1 (en) | 2003-12-19 | 2006-12-21 | Emisphere Technologies, Inc. | Oral GLP-1 formulations |
| US20050143303A1 (en) | 2003-12-26 | 2005-06-30 | Nastech Pharmaceutical Company Inc. | Intranasal administration of glucose-regulating peptides |
| US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
| CA2563533C (en) | 2004-04-15 | 2013-10-01 | Shmuel A. Ben-Sasson | Compositions capable of facilitating penetration across a biological barrier |
| CN101027318B (zh) | 2004-07-19 | 2016-05-25 | 比奥孔有限公司 | 胰岛素-低聚物共轭物,制剂及其用途 |
| US20060046962A1 (en) | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| EP1789075A4 (en) | 2004-08-25 | 2009-07-01 | Uab Research Foundation | ABSORPTION ENHANCER FOR DRUG ADMINISTRATION |
| DK1814590T4 (da) * | 2004-11-01 | 2014-02-24 | Amylin Pharmaceuticals Llc | Behandling af obesitet og beslægtede sygdomme. |
| US8389472B2 (en) * | 2005-08-19 | 2013-03-05 | Amylin Pharmaceuticals, Llc | Exendin-4 to treat nonalcoholic steatohepatitis and nonalcoholic fatty liver disease |
| EP2722054B1 (en) | 2005-09-06 | 2018-03-21 | Oramed Pharmaceuticals Inc. | Methods and compositions for oral administration of proteins |
| US20070086972A1 (en) | 2005-09-12 | 2007-04-19 | Jacob Birnbaum | Hair growth compositions and methods for treating hair loss or related conditions |
| US20070077283A1 (en) | 2005-09-30 | 2007-04-05 | Nastech Pharmaceutical Company Inc. | Method of enhancing transmucosal delivery of therapeutic compounds |
| CN101095942B (zh) | 2006-06-30 | 2011-11-16 | 北京民海生物科技有限公司 | 一种包含稳定剂的Exendin-4注射剂药物配方 |
| WO2008142482A2 (en) | 2006-11-01 | 2008-11-27 | Pronova Biopharma Norge As | Omega-3 lipid compounds |
| PL2144618T5 (pl) | 2007-03-28 | 2025-07-21 | Aker Biomarine Human Ingredients As | Bio-skuteczne kompozycje oleju z kryla |
| RU2504373C2 (ru) * | 2008-03-26 | 2014-01-20 | ОРАМЕД Лтд. | Способы и композиции для перорального введения протеинов |
| CA2723434C (en) * | 2008-05-05 | 2018-01-23 | Oramed Ltd. | Methods and compositions for oral administration of exenatide |
| PE20100156A1 (es) * | 2008-06-03 | 2010-02-23 | Boehringer Ingelheim Int | Tratamiento de nafld |
| JPWO2009151125A1 (ja) * | 2008-06-13 | 2011-11-17 | 持田製薬株式会社 | 肝障害の診断及び治療 |
| WO2009154230A1 (ja) | 2008-06-17 | 2009-12-23 | 持田製薬株式会社 | 非アルコール性脂肪肝炎の予防/改善・治療薬 |
| US20090312302A1 (en) * | 2008-06-17 | 2009-12-17 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating nonalcoholic fatty liver disease-associated disorders |
| ES2558842T3 (es) * | 2008-06-17 | 2016-02-09 | Indiana University Research And Technology Corporation | Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad |
| WO2010002418A2 (en) | 2008-07-01 | 2010-01-07 | The Johns Hopkins University | Quick-dissolving oral thin film for targeted delivery of therapeutic agents |
| CN102123697B (zh) * | 2008-08-18 | 2015-06-10 | 安特拉贝欧有限公司 | 用于口服给予蛋白质的方法和组合物 |
| UY32177A (es) | 2008-10-16 | 2010-05-31 | Boehringer Ingelheim Int | Tratamiento de diabetes en pacientes con control glucémico insuficiente a pesar de la terapia con fármaco, oral o no, antidiabético |
| KR101783817B1 (ko) | 2009-05-08 | 2017-10-23 | 프로노바 바이오파마 너지 에이에스 | 심혈관 질병, 대사 질병, 및 염증성 질환 분야관련 질병의 치료를 위한 다중 불포화 지방산 |
| US20120202849A1 (en) | 2009-10-12 | 2012-08-09 | Anil Pareek | Pharmaceutical compositions for the treatment/prophylaxis of non-alcoholic fatty liver disease |
| CN103988973A (zh) | 2009-12-30 | 2014-08-20 | 索莱有限责任公司 | 大豆乳清蛋白组合物及其回收方法 |
| US20130273154A1 (en) | 2011-03-02 | 2013-10-17 | Joseph M. Fayad | Oral formulations Mimetic of Roux-en-Y gastric bypass actions on the ileal brake; Compositions, Methods of Treatment, Diagnostics and Systems for treatment of metabolic syndrome manifestations including insulin resistance, fatty liver disease, hpperlipidemia, and type 2 diabetes |
| PH12012502524A1 (en) * | 2010-06-24 | 2014-02-10 | Boehringer Ingelheim Int | Diabetes therapy |
| CA2804506C (en) * | 2010-07-06 | 2018-08-21 | Janssen Pharmaceutica Nv | Formulation for co-therapy treatment of diabetes |
| ES2659763T3 (es) * | 2011-02-14 | 2018-03-19 | The Regents Of The University Of Michigan | Composiciones y procedimientos para el tratamiento de obesidad y trastornos relacionados |
| US20120264824A1 (en) | 2011-04-15 | 2012-10-18 | Mochida Pharmaceutical Co., Ltd. | Compositions and methods for treating non-alcoholic steatohepatitis |
| CN102219850A (zh) * | 2011-05-03 | 2011-10-19 | 上海格尼生物技术有限公司 | 新的长效glp-1化合物 |
| US20140220134A1 (en) * | 2011-06-24 | 2014-08-07 | Astrazeneca Pharamceuticals LP | Method for treating diabetes with extended release formulation of glp-1 receptor agonists |
| WO2013010289A1 (zh) | 2011-07-15 | 2013-01-24 | Chan Tu Cheng | 填充式工件表面饰化方法 |
| US9458214B2 (en) * | 2011-09-26 | 2016-10-04 | Novartis Ag | Dual function fibroblast growth factor 21 proteins |
| WO2013102899A1 (en) | 2012-01-03 | 2013-07-11 | Oramed Ltd. | Methods and compositions for treating diabetes |
| ES2912138T3 (es) * | 2012-02-01 | 2022-05-24 | Oramed Ltd | Composiciones que contienen inhibidores de proteasa, composiciones que comprenden las mismas y métodos para producir y usar las misma |
| WO2013148966A1 (en) * | 2012-03-28 | 2013-10-03 | Amylin Pharmaceuticals, Llc | Transmucosal delivery of engineered polypeptides |
| CN104902921A (zh) * | 2013-01-03 | 2015-09-09 | 奥拉姆德有限公司 | 用于治疗nafld、肝性脂肪变性及其后遗症的方法和组合物 |
-
2014
- 2014-01-02 CN CN201480003919.4A patent/CN104902921A/zh active Pending
- 2014-01-02 EP EP22205280.5A patent/EP4215205A1/en not_active Withdrawn
- 2014-01-02 WO PCT/IL2014/050007 patent/WO2014106846A2/en not_active Ceased
- 2014-01-02 EP EP14735143.1A patent/EP2941267B1/en active Active
- 2014-01-02 JP JP2015551250A patent/JP2016505613A/ja active Pending
- 2014-01-02 CN CN201910287860.0A patent/CN110151979A/zh active Pending
- 2014-01-02 US US14/759,060 patent/US20150335715A1/en not_active Abandoned
-
2018
- 2018-07-11 JP JP2018131875A patent/JP2018197240A/ja active Pending
- 2018-11-19 US US16/195,184 patent/US10967051B2/en active Active
-
2020
- 2020-06-12 JP JP2020102461A patent/JP2020180126A/ja active Pending
-
2021
- 2021-03-19 US US17/206,574 patent/US20220000986A1/en not_active Abandoned
-
2022
- 2022-09-29 JP JP2022156787A patent/JP2023002570A/ja active Pending
-
2023
- 2023-12-21 US US18/392,074 patent/US20240181018A1/en not_active Abandoned
-
2025
- 2025-03-13 JP JP2025040577A patent/JP2025106279A/ja active Pending
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