JP2018183141A5 - - Google Patents

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JP2018183141A5
JP2018183141A5 JP2018111416A JP2018111416A JP2018183141A5 JP 2018183141 A5 JP2018183141 A5 JP 2018183141A5 JP 2018111416 A JP2018111416 A JP 2018111416A JP 2018111416 A JP2018111416 A JP 2018111416A JP 2018183141 A5 JP2018183141 A5 JP 2018183141A5
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population
culture medium
chondrocytes
polypeptide
pluripotent stem
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JP2018111416A
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JP2018183141A (ja
JP6898657B2 (ja
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Priority to JP2021093070A priority Critical patent/JP2021153591A/ja
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Priority to JP2022196593A priority patent/JP2023068668A/ja
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JP2018111416A 2012-10-29 2018-06-11 軟骨細胞から多能性幹細胞を製造する方法 Active JP6898657B2 (ja)

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JP2021093070A JP2021153591A (ja) 2012-10-29 2021-06-02 軟骨細胞から多能性幹細胞を製造する方法
JP2022196593A JP2023068668A (ja) 2012-10-29 2022-12-08 軟骨細胞から多能性幹細胞を製造する方法

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US201261719901P 2012-10-29 2012-10-29
US61/719,901 2012-10-29
JP2015539924A JP6399558B2 (ja) 2012-10-29 2013-10-29 軟骨細胞から多能性幹細胞を製造する方法

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JP2018183141A JP2018183141A (ja) 2018-11-22
JP2018183141A5 true JP2018183141A5 (https=) 2019-09-19
JP6898657B2 JP6898657B2 (ja) 2021-07-07

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JP2015539924A Active JP6399558B2 (ja) 2012-10-29 2013-10-29 軟骨細胞から多能性幹細胞を製造する方法
JP2018111416A Active JP6898657B2 (ja) 2012-10-29 2018-06-11 軟骨細胞から多能性幹細胞を製造する方法
JP2021093070A Pending JP2021153591A (ja) 2012-10-29 2021-06-02 軟骨細胞から多能性幹細胞を製造する方法
JP2022196593A Pending JP2023068668A (ja) 2012-10-29 2022-12-08 軟骨細胞から多能性幹細胞を製造する方法

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JP2021093070A Pending JP2021153591A (ja) 2012-10-29 2021-06-02 軟骨細胞から多能性幹細胞を製造する方法
JP2022196593A Pending JP2023068668A (ja) 2012-10-29 2022-12-08 軟骨細胞から多能性幹細胞を製造する方法

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US (2) US9914911B2 (https=)
EP (1) EP2912166B1 (https=)
JP (4) JP6399558B2 (https=)
WO (1) WO2014070797A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10724005B2 (en) 2012-09-28 2020-07-28 Scripps Health Methods of differentiating stem cells into chondrocytes
EP2912166B1 (en) * 2012-10-29 2019-05-01 Scripps Health Methods of producing pluripotent stem cells from chondrocytes
JP6324395B2 (ja) 2012-10-29 2018-05-16 スクリップス ヘルス 軟骨細胞を移植する方法
US9668892B2 (en) 2013-03-11 2017-06-06 Endospan Ltd. Multi-component stent-graft system for aortic dissections
US10758574B2 (en) * 2016-04-28 2020-09-01 The Board Of Trustees Of The Leland Stanford Junior University Cartilage cells with a high regenerative potential and low immune response for use in cellular therapy
CN108714218B (zh) * 2016-04-28 2021-02-26 中国医学科学院血液病医院(中国医学科学院血液学研究所) 一种利用重编程效应治疗白血病的方法
CN106267363B (zh) * 2016-09-18 2019-06-14 辽宁聚高智造科技有限公司 一种人造骨
WO2020130147A1 (ja) * 2018-12-21 2020-06-25 国立大学法人京都大学 ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物
WO2021100796A1 (ja) * 2019-11-20 2021-05-27 一丸ファルコス株式会社 軟骨を作製するための剤及び軟骨の作製方法
JP7774794B2 (ja) * 2021-06-17 2025-11-25 学校法人近畿大学 人工耳介および人工軟骨組織の骨格構造

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399347A (en) 1987-06-24 1995-03-21 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
US5645851A (en) 1994-02-28 1997-07-08 Moore; Eugene R. Product for alleviating the symptons of arthritis in mammals
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
GB9503492D0 (en) 1995-02-22 1995-04-12 Ed Geistlich S Hne A G F R Che Chemical product
US6025327A (en) 1997-08-08 2000-02-15 Biocell Technology, Llc Hydrolyzed collagen type II and use thereof
US6511958B1 (en) 1997-08-14 2003-01-28 Sulzer Biologics, Inc. Compositions for regeneration and repair of cartilage lesions
US20030026786A1 (en) 1999-06-04 2003-02-06 Mark F. Pittenger Chondrogenic differentiation of human mesenchymal stem cells
EP1254670A1 (en) 2001-05-03 2002-11-06 Stichting Katholieke Universiteit Type II collagen matrices for use in cartilage engineering
US6780841B2 (en) 2001-11-13 2004-08-24 Biocell Technology, Llc Hyaluronic acid and chondroitin sulfate based hydrolyzed collagen type II and method of making same
CA2412012C (en) 2001-11-20 2011-08-02 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage
US6852331B2 (en) 2002-02-11 2005-02-08 Taipei Biotechnology Ltd., Inc. Fabrication of a cartilage implant
ES2265199B1 (es) * 2003-06-12 2008-02-01 Cellerix, S.L. Celulas madre adultas multipotentes procedentes de condrocitos desdiferenciados y sus aplicaciones.
BRPI0513897A (pt) 2004-07-29 2008-05-20 Stem Cell Innovations Inc diferenciação de células-tronco
CN101506355B (zh) 2004-09-24 2012-06-27 成血管细胞系统公司 多能扩增间充质前体细胞子代(memp)及其应用
KR20070085288A (ko) 2004-09-24 2007-08-27 안지오블라스트 시스템스 인코퍼레이티드 간엽 전구세포의 증식 및/또는 생존성 증강 방법
US20060189840A1 (en) 2005-02-18 2006-08-24 Acorn Cardiovascular, Inc. Transmyocardial delivery of cardiac wall tension relief
ES2329636B2 (es) * 2006-02-17 2010-07-26 Universitat De Valencia, Estudi General (Participa Con El 70%) Uso del factor pedf para inducir la auto-renovacion de celulas madre.
FR2900155B1 (fr) 2006-04-21 2008-06-27 Diana Naturals Sa Hydrolisat de cartilage aviaire, procede d'obtention et utilisations
CN101721349B (zh) 2008-10-16 2011-07-20 常州百瑞吉生物医药有限公司 可注射原位交联水凝胶及其制备方法和用途
KR101091028B1 (ko) 2009-07-02 2011-12-09 아주대학교산학협력단 체내 주입형 하이드로젤 및 이의 생의학적 용도
JP5636174B2 (ja) 2009-07-10 2014-12-03 学校法人近畿大学 間葉系細胞または軟骨細胞の製法ならびに発癌性の抑制方法
CA2777720C (en) * 2009-10-16 2020-10-06 The Scripps Research Institute Induction of pluripotent cells
CA2725728C (en) 2009-11-24 2014-01-28 University Of Connecticut Differentiation of human embryonic and induced pluripotent stem cells
KR100990436B1 (ko) 2009-11-30 2010-10-29 동국대학교 산학협력단 중간엽 줄기세포를 DKK-1 또는 sFRP-1을 이용하여 연골세포로 분화시키는 방법
EP2529009A4 (en) 2010-01-28 2013-11-13 Univ Queensland METHOD OF STEM CELL DIFFERENTIATION
CN102959076B (zh) 2010-03-31 2015-09-16 斯克里普斯研究所 重编程细胞
US9029145B2 (en) 2010-04-08 2015-05-12 The University Court Of The University Of Edinburgh Chondrogenic progenitor cells, protocol for derivation of cells and uses thereof
CN101810855B (zh) 2010-05-20 2012-06-13 广州创尔生物技术有限公司 一种ⅱ型胶原关节软骨修复液及其制备方法
CA2843050A1 (en) 2010-07-26 2012-02-02 The University Of Manchester Targeted differentiation of stem cells
CN101934092A (zh) 2010-08-27 2011-01-05 中国人民解放军第三军医大学第一附属医院 用于软骨再生修复的注射型软骨仿生基质材料及使用方法
US20120087868A1 (en) 2010-10-08 2012-04-12 Gabriele Todd Nanoparticle-loaded cells
KR101340458B1 (ko) 2010-11-02 2013-12-11 서울대학교산학협력단 하이드로겔을 포함하는 연골 이식용 조성물
US8663675B2 (en) 2010-11-18 2014-03-04 Jalaledin Ghanavi Injectable matrix having a polymer and a stem cell niche composed of cup-shaped nanoparticles containing growth factors or physiological agents for organ reconstruction
ES2590752T3 (es) 2011-03-18 2016-11-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Medios de diferenciación condrogénica y métodos para inducir la diferenciación condrogénica de células
US10724005B2 (en) 2012-09-28 2020-07-28 Scripps Health Methods of differentiating stem cells into chondrocytes
EP2912166B1 (en) * 2012-10-29 2019-05-01 Scripps Health Methods of producing pluripotent stem cells from chondrocytes
JP6324395B2 (ja) 2012-10-29 2018-05-16 スクリップス ヘルス 軟骨細胞を移植する方法
EP2980207B1 (en) * 2013-03-25 2018-12-05 Foundation for Biomedical Research and Innovation at Kobe Cell sorting method

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