JP2018176412A - 検出装置およびその注入口構造 - Google Patents
検出装置およびその注入口構造 Download PDFInfo
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- JP2018176412A JP2018176412A JP2017193360A JP2017193360A JP2018176412A JP 2018176412 A JP2018176412 A JP 2018176412A JP 2017193360 A JP2017193360 A JP 2017193360A JP 2017193360 A JP2017193360 A JP 2017193360A JP 2018176412 A JP2018176412 A JP 2018176412A
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- 238000001514 detection method Methods 0.000 title abstract description 28
- 238000002347 injection Methods 0.000 title abstract 7
- 239000007924 injection Substances 0.000 title abstract 7
- 239000012530 fluid Substances 0.000 claims abstract description 50
- 230000001788 irregular Effects 0.000 claims description 3
- 239000000243 solution Substances 0.000 abstract 1
- 230000002745 absorbent Effects 0.000 description 7
- 239000002250 absorbent Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 3
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000013399 early diagnosis Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012123 point-of-care testing Methods 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B7/00—Microstructural systems; Auxiliary parts of microstructural devices or systems
- B81B7/0032—Packages or encapsulation
- B81B7/0061—Packages or encapsulation suitable for fluid transfer from the MEMS out of the package or vice versa, e.g. transfer of liquid, gas, sound
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
- A61B5/1405—Devices for taking blood samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/05—Microfluidics
- B81B2201/058—Microfluidics not provided for in B81B2201/051 - B81B2201/054
Abstract
Description
200、200a、200b 注入口構造
210 注入口部
212 内表面
214 傾斜表面
214a 一側
214b 他側
216 底面
220、220a、220b マイクロ構造
221 側面
224 一側
225 上表面
226、226a 下表面
300 マイクロ流路
D 注入口部の直径
F 流体
H 垂直線間距離
W マイクロ流路の直径
Claims (11)
- マイクロ流路に接続されるのに適した注入口構造であって、
内表面を有する注入口部と、
前記注入口部内に配置され、且つ前記内表面に接続された少なくとも1つのマイクロ構造と、
を含み、流体が前記注入口部に注入された時、前記マイクロ構造が、前記流体の表面張力を破壊して、毛細管現象により前記流体を前記マイクロ流路に流入させる注入口構造。 - 前記マイクロ構造が、前記注入口部の前記内表面から突出する凸型マイクロ構造である請求項1に記載の注入口構造。
- 前記マイクロ構造が、前記注入口部の前記内表面に埋め込まれる凹型マイクロ構造である請求項1に記載の注入口構造。
- 前記マイクロ構造の数が複数である時、前記複数のマイクロ構造が、等間隔に離間配置される請求項1に記載の注入口構造。
- 前記注入口部が、さらに、傾斜表面および底面を有し、前記内表面が、前記傾斜表面と前記底面の間に接続され、前記内表面が、前記底面に垂直または斜めに接続された請求項1に記載の注入口構造。
- 前記マイクロ構造の一側が、前記傾斜表面と前記内表面の間の境界に設置された請求項5に記載の注入口構造。
- 前記マイクロ構造の下表面と前記注入口部の前記底面の間に垂直線間距離がある請求項5に記載の注入口構造。
- 前記マイクロ構造の下表面が、前記注入口部の前記底面と一列に並べられた請求項5に記載の注入口構造。
- 前記注入口部の上から見た形状が、円形であり、前記マイクロ流路の直径が、前記注入口部の直径よりも小さいか、それに等しい請求項1に記載の注入口構造。
- 前記マイクロ構造の上から見た形状が、多角形、円弧形、または不規則形状である請求項1に記載の注入口構造。
- 内表面を有する注入口部と、
前記注入口部内に配置され、且つ前記内表面に接続された少なくとも1つのマイクロ構造と、
を含む注入口構造と、
前記注入口構造に接続されたマイクロ流路と、
を含み、流体が前記注入口構造の前記注入口部に注入された時、前記マイクロ構造が、前記流体の表面張力を破壊して、毛細管現象により前記流体を前記マイクロ流路に流入させる検出装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710256374.3A CN108722504A (zh) | 2017-04-19 | 2017-04-19 | 检测装置及其注入口结构 |
CN201710256374.3 | 2017-04-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2018176412A true JP2018176412A (ja) | 2018-11-15 |
JP6498249B2 JP6498249B2 (ja) | 2019-04-10 |
Family
ID=60042970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017193360A Active JP6498249B2 (ja) | 2017-04-19 | 2017-10-03 | 検出装置およびその注入口構造 |
Country Status (4)
Country | Link |
---|---|
US (1) | US20180304252A1 (ja) |
EP (1) | EP3391967B1 (ja) |
JP (1) | JP6498249B2 (ja) |
CN (1) | CN108722504A (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10685806B2 (en) * | 2016-10-14 | 2020-06-16 | L-3 Communications Corporation-Insight Technology Division | Image intensifier bloom mitigation |
AU2018215821B2 (en) * | 2017-02-06 | 2023-02-02 | Efa - Engineering For All Ltd. | Portable digital diagnostic device |
EP3772371A1 (en) * | 2019-08-06 | 2021-02-10 | EFA - Engineering For All Ltd. | Micromixer |
Citations (10)
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JPS63500330A (ja) * | 1985-05-31 | 1988-02-04 | ミユアレツクス コオ−ポレイシヨン | 横行の流れ検定方法及び装置 |
WO1994004272A1 (en) * | 1992-08-26 | 1994-03-03 | Hypoguard (Uk) Limited | Fluid testing device |
WO2006123578A1 (ja) * | 2005-05-19 | 2006-11-23 | Konica Minolta Medical & Graphic, Inc. | 検体中の標的物質を分析するための検査チップおよびマイクロ総合分析システム |
JP2009002927A (ja) * | 2007-05-23 | 2009-01-08 | Enplas Corp | 流体取扱ユニットおよびそれを用いた流体取扱装置 |
JP4597664B2 (ja) * | 2002-06-07 | 2010-12-15 | オーミック・アクチボラゲット | 微細流体構造 |
JP4900247B2 (ja) * | 2005-12-14 | 2012-03-21 | 日本電気株式会社 | マイクロチップおよびこれを用いた分析方法 |
JP4931345B2 (ja) * | 2003-12-20 | 2012-05-16 | ベーリンガー インゲルヘイム マイクロパーツ ゲーエムベーハー | 流体を誘導するための少なくとも1つのシステムを気泡を残さずに充填するための微細構造配置、かかる配置を備える装置、および充填方法 |
US20120156765A1 (en) * | 2009-09-01 | 2012-06-21 | Koninklijke Philips Electronics N.V. | Fluid filtering device |
JP5475692B2 (ja) * | 2008-02-27 | 2014-04-16 | ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血漿の分離装置 |
JP6019485B2 (ja) * | 2011-03-24 | 2016-11-02 | ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツングBoehringer Ingelheim microParts GmbH | 血液濾過器具及び方法 |
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-
2017
- 2017-04-19 CN CN201710256374.3A patent/CN108722504A/zh active Pending
- 2017-06-14 US US15/622,086 patent/US20180304252A1/en not_active Abandoned
- 2017-09-18 EP EP17191599.4A patent/EP3391967B1/en active Active
- 2017-10-03 JP JP2017193360A patent/JP6498249B2/ja active Active
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JPS63500330A (ja) * | 1985-05-31 | 1988-02-04 | ミユアレツクス コオ−ポレイシヨン | 横行の流れ検定方法及び装置 |
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WO1994004272A1 (en) * | 1992-08-26 | 1994-03-03 | Hypoguard (Uk) Limited | Fluid testing device |
JP4597664B2 (ja) * | 2002-06-07 | 2010-12-15 | オーミック・アクチボラゲット | 微細流体構造 |
JP4931345B2 (ja) * | 2003-12-20 | 2012-05-16 | ベーリンガー インゲルヘイム マイクロパーツ ゲーエムベーハー | 流体を誘導するための少なくとも1つのシステムを気泡を残さずに充填するための微細構造配置、かかる配置を備える装置、および充填方法 |
WO2006123578A1 (ja) * | 2005-05-19 | 2006-11-23 | Konica Minolta Medical & Graphic, Inc. | 検体中の標的物質を分析するための検査チップおよびマイクロ総合分析システム |
JP4900247B2 (ja) * | 2005-12-14 | 2012-03-21 | 日本電気株式会社 | マイクロチップおよびこれを用いた分析方法 |
JP2009002927A (ja) * | 2007-05-23 | 2009-01-08 | Enplas Corp | 流体取扱ユニットおよびそれを用いた流体取扱装置 |
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US20120156765A1 (en) * | 2009-09-01 | 2012-06-21 | Koninklijke Philips Electronics N.V. | Fluid filtering device |
JP6019485B2 (ja) * | 2011-03-24 | 2016-11-02 | ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツングBoehringer Ingelheim microParts GmbH | 血液濾過器具及び方法 |
Also Published As
Publication number | Publication date |
---|---|
US20180304252A1 (en) | 2018-10-25 |
EP3391967B1 (en) | 2020-04-01 |
JP6498249B2 (ja) | 2019-04-10 |
EP3391967A1 (en) | 2018-10-24 |
CN108722504A (zh) | 2018-11-02 |
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