JP2017537983A5 - - Google Patents
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- Publication number
- JP2017537983A5 JP2017537983A5 JP2017550461A JP2017550461A JP2017537983A5 JP 2017537983 A5 JP2017537983 A5 JP 2017537983A5 JP 2017550461 A JP2017550461 A JP 2017550461A JP 2017550461 A JP2017550461 A JP 2017550461A JP 2017537983 A5 JP2017537983 A5 JP 2017537983A5
- Authority
- JP
- Japan
- Prior art keywords
- mucoadhesive
- formulation
- concentration
- xylitol
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 13
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 13
- 235000010447 xylitol Nutrition 0.000 claims description 13
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 13
- 229960002675 xylitol Drugs 0.000 claims description 13
- 239000000811 xylitol Substances 0.000 claims description 13
- 210000002200 mouth mucosa Anatomy 0.000 claims description 8
- 230000003232 mucoadhesive effect Effects 0.000 claims 32
- 238000009472 formulation Methods 0.000 claims 26
- 239000000203 mixture Substances 0.000 claims 26
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 7
- 229920002807 Thiomer Polymers 0.000 claims 5
- 235000011187 glycerol Nutrition 0.000 claims 5
- 150000005846 sugar alcohols Chemical class 0.000 claims 5
- 239000007788 liquid Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229920000058 polyacrylate Polymers 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 238000011065 in-situ storage Methods 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462089942P | 2014-12-10 | 2014-12-10 | |
| US62/089,942 | 2014-12-10 | ||
| PCT/US2015/061743 WO2016094054A1 (en) | 2014-12-10 | 2015-11-20 | Composition for the relief of dry mouth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537983A JP2017537983A (ja) | 2017-12-21 |
| JP2017537983A5 true JP2017537983A5 (cg-RX-API-DMAC7.html) | 2018-12-06 |
| JP6783244B2 JP6783244B2 (ja) | 2020-11-11 |
Family
ID=56107939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017550461A Active JP6783244B2 (ja) | 2014-12-10 | 2015-11-20 | 口渇の軽減のための組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10772908B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3229792B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6783244B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015361122B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2970146C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2982077T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX388182B (cg-RX-API-DMAC7.html) |
| PL (1) | PL3229792T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016094054A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017117650A1 (en) | 2016-01-10 | 2017-07-13 | Smilesonica Inc | Viscosity and stability modified ultrasound gel |
| CN105833278B (zh) * | 2016-04-25 | 2018-05-08 | 北京嘉安医疗器械科技有限公司 | 用于治疗口腔干燥和口腔疾病的组合物 |
| CA3054654A1 (en) * | 2017-02-22 | 2018-08-30 | Smilesonica Inc. | Artificial saliva, related methods, and uses |
| CA3195741A1 (en) * | 2020-10-15 | 2022-04-21 | Peter M. Milgrom | A thickened silver diamine fluoride composition |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3970747A (en) * | 1974-03-11 | 1976-07-20 | Colgate-Palmolive Company | Humectant sweetener |
| US4340583A (en) * | 1979-05-23 | 1982-07-20 | J. M. Huber Corporation | High fluoride compatibility dentifrice abrasives and compositions |
| US4997654A (en) * | 1989-08-14 | 1991-03-05 | Warner-Lambert Company | Method for increasing salivation for xerostomia patients |
| US5496558A (en) * | 1993-03-02 | 1996-03-05 | Block Drug Company Inc. | Solid form xerostomia product |
| US5900230A (en) * | 1997-08-18 | 1999-05-04 | Squigle, Inc. | Dental products to treat and prevent periodontal disease |
| EP1068871A1 (en) | 1999-07-07 | 2001-01-17 | Jean-Paul Perraudin | Novel methods and medicament for treating infections diseases involving microbial biofilms |
| BRPI0514037B8 (pt) | 2004-08-02 | 2021-05-25 | Glaxo Group Ltd | composição para o cuidado oral |
| JP2011514338A (ja) | 2008-02-25 | 2011-05-06 | シグナム バイオサイエンシーズ， インコーポレイテッド | 脂質修飾システイン含有ペプチドを含むペプチドを利用するための局所用組成物および方法 |
| US8735374B2 (en) | 2009-07-31 | 2014-05-27 | Intelgenx Corp. | Oral mucoadhesive dosage form |
| JP5433355B2 (ja) | 2009-09-16 | 2014-03-05 | サンスター株式会社 | 口腔用組成物 |
| US8658139B1 (en) | 2010-02-27 | 2014-02-25 | Squigle, Inc. | Prevention and treatment of oral diseases |
| WO2011130009A1 (en) | 2010-04-14 | 2011-10-20 | Isp Investments Inc. | Oral care compositions |
| MX2012013955A (es) | 2010-06-23 | 2013-01-24 | Colgate Palmolive Co | Composiciones terapeuticas bucales. |
| US20120053130A1 (en) * | 2010-08-30 | 2012-03-01 | Bristol-Myers Squibb Company | Composition for enhancing absorption of a drug and method |
| ES2753198T5 (es) | 2010-12-16 | 2023-05-31 | Amgen Europe Gmbh | Formas farmacéuticas orales de liberación controlada de fármacos poco solubles y sus usos |
| WO2012087325A1 (en) | 2010-12-23 | 2012-06-28 | Colgate-Palmolive Company | Aqueous oral care composition comprising xanthan gum, cellulose gum and carbomer |
| LT2758037T (lt) | 2011-09-23 | 2018-06-25 | Emerald Hilton Davis, Llc | Savitvarkė nanostruktūros dalelė ir jos gavimo būdas |
| SG11201402061UA (en) * | 2011-12-15 | 2014-06-27 | Colgate Palmolive Co | Aqueous oral care compositions |
| US9724542B2 (en) | 2012-10-12 | 2017-08-08 | Premier Dental Products Company | Remineralizing and desensitizing compositions, treatments and methods of manufacture |
-
2015
- 2015-11-20 US US15/529,210 patent/US10772908B2/en active Active
- 2015-11-20 AU AU2015361122A patent/AU2015361122B2/en active Active
- 2015-11-20 MX MX2017007597A patent/MX388182B/es unknown
- 2015-11-20 CA CA2970146A patent/CA2970146C/en active Active
- 2015-11-20 WO PCT/US2015/061743 patent/WO2016094054A1/en not_active Ceased
- 2015-11-20 PL PL15867121.4T patent/PL3229792T3/pl unknown
- 2015-11-20 JP JP2017550461A patent/JP6783244B2/ja active Active
- 2015-11-20 EP EP15867121.4A patent/EP3229792B1/en active Active
- 2015-11-20 ES ES15867121T patent/ES2982077T3/es active Active
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