JP2017535601A5 - - Google Patents
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- Publication number
- JP2017535601A5 JP2017535601A5 JP2017543329A JP2017543329A JP2017535601A5 JP 2017535601 A5 JP2017535601 A5 JP 2017535601A5 JP 2017543329 A JP2017543329 A JP 2017543329A JP 2017543329 A JP2017543329 A JP 2017543329A JP 2017535601 A5 JP2017535601 A5 JP 2017535601A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- apilimod
- therapeutic
- renal
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462077127P | 2014-11-07 | 2014-11-07 | |
| US62/077,127 | 2014-11-07 | ||
| PCT/US2015/059512 WO2016073877A1 (en) | 2014-11-07 | 2015-11-06 | Apilimod for use in the treatment of renal cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017535601A JP2017535601A (ja) | 2017-11-30 |
| JP2017535601A5 true JP2017535601A5 (OSRAM) | 2018-12-13 |
| JP6705828B2 JP6705828B2 (ja) | 2020-06-03 |
Family
ID=54548302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017543329A Expired - Fee Related JP6705828B2 (ja) | 2014-11-07 | 2015-11-06 | 腎癌の処置に使用するためのアピリモド |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US10206910B2 (OSRAM) |
| EP (2) | EP3581184B1 (OSRAM) |
| JP (1) | JP6705828B2 (OSRAM) |
| KR (1) | KR20170098812A (OSRAM) |
| CN (1) | CN107249638B (OSRAM) |
| AU (1) | AU2015342869A1 (OSRAM) |
| BR (1) | BR112017008799A2 (OSRAM) |
| CA (1) | CA2966359A1 (OSRAM) |
| ES (1) | ES2741399T3 (OSRAM) |
| HU (1) | HUE044557T2 (OSRAM) |
| IL (1) | IL251905B (OSRAM) |
| MX (1) | MX377593B (OSRAM) |
| PL (1) | PL3215158T3 (OSRAM) |
| PT (1) | PT3215158T (OSRAM) |
| RU (1) | RU2727802C2 (OSRAM) |
| WO (1) | WO2016073877A1 (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6855243B2 (ja) | 2014-01-24 | 2021-04-07 | エイアイ・セラピューティクス・インコーポレーテッド | 癌治療のためのアピリモド（ａｐｉｌｉｍｏｄ）組成物 |
| US20190209576A1 (en) * | 2014-11-07 | 2019-07-11 | AI Therapeutics, Inc. | Apilimod for use in the treatment of colorectal cancer |
| KR20170098812A (ko) | 2014-11-07 | 2017-08-30 | 램 테라퓨틱스, 인코포레이티드 | 신장암의 치료에 사용하기 위한 아필리모드 |
| AU2017210324A1 (en) * | 2016-01-21 | 2018-08-16 | AI Therapeutics, Inc. | Biomarkers for treating cancer with apilimod |
| KR20190068519A (ko) * | 2016-08-25 | 2019-06-18 | 에이아이 테라퓨틱스, 인코포레이티드 | PIKfyve 억제제를 포함하는 조성물 및 RANK 신호전달의 억제와 관련된 방법 |
| US20190365771A1 (en) * | 2016-10-12 | 2019-12-05 | AI Therapeutics, Inc. | Apilimod compositions and methods for using same in the treatment of alzheimer's disease |
| KR102642378B1 (ko) | 2017-03-24 | 2024-02-28 | 픽사이 인코포레이티드 | 유용한 약학적 적용을 갖는 융합된 트리아졸로-피리미딘 화합물 |
| US11524053B2 (en) | 2018-01-26 | 2022-12-13 | The Regents Of The University Of California | Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents |
| JP7354123B2 (ja) | 2018-02-21 | 2023-10-02 | エイアイ・セラピューティクス・インコーポレーテッド | アピリモドとグルタミン酸作動薬を用いた併用療法 |
| IL293131A (en) | 2019-11-25 | 2022-07-01 | Univ California | Long-acting vegf inhibitors for intraocular neovascularization |
| MX2022008627A (es) | 2020-01-13 | 2022-11-08 | Verge Analytics Inc | Pirazolo-pirimidinas sustituidas y usos de las mismas. |
| CN114306370A (zh) * | 2021-12-31 | 2022-04-12 | 北京悦康科创医药科技股份有限公司 | 反义寡核苷酸在制备治疗肾癌药物中的应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| CA2176348C (en) | 1993-11-12 | 2004-11-02 | Sanjay Tyagi | Hybridization probes for nucleic acid detection, universal stems, methods and kits |
| US6693097B2 (en) | 2001-11-30 | 2004-02-17 | Synta Pharmaceuticals Corp. | Pyrimidine compounds |
| NZ584288A (en) | 2004-02-06 | 2011-10-28 | Elan Pharm Inc | Methods and compositions for treating tumors and metastatic disease |
| WO2005112938A2 (en) | 2004-04-13 | 2005-12-01 | Synta Pharmaceuticals Corp. | Disalt inhibitors of il-12 production |
| AU2005282241B2 (en) | 2004-09-08 | 2011-03-03 | Chelsea Therapeutics, Inc. | Quinazoline derivatives as metabolically inert antifolate compounds. |
| US7923557B2 (en) | 2004-11-10 | 2011-04-12 | Synta Pharmaceuticals Corporation | Process for preparing trisubstituted pyrimidine compounds |
| US7863270B2 (en) | 2005-05-13 | 2011-01-04 | Synta Pharmaceuticals Corp. | IL-12 modulatory compounds |
| WO2006128129A2 (en) | 2005-05-26 | 2006-11-30 | Synta Pharmaceuticals Corp. | Method for treating cancer |
| PT2385053E (pt) | 2005-11-17 | 2013-12-17 | Osi Pharm Inc | Intermediários para a preparação de compostos bicíclicos condensados como inibidores mtor |
| AR057960A1 (es) | 2005-12-02 | 2007-12-26 | Osi Pharm Inc | Inhibidores de proteina quinasa biciclicos |
| US7659274B2 (en) | 2006-01-25 | 2010-02-09 | Osi Pharmaceuticals, Inc. | Unsaturated mTOR inhibitors |
| CA2658394C (en) | 2006-07-12 | 2016-08-16 | University Of Tennessee Research Foundation | Substituted acylanilides and methods of use thereof |
| EP2118087B1 (en) | 2007-02-06 | 2012-03-28 | Novartis AG | Pi 3-kinase inhibitors and methods of their use |
| RU2438664C2 (ru) | 2007-05-15 | 2012-01-10 | Пирамал Лайф Сайнсиз Лимитед | Синергическая фармацевтическая комбинация для лечения рака |
| DE102007036076A1 (de) * | 2007-08-01 | 2009-02-05 | Bayer Healthcare Aktiengesellschaft | Dipeptoid-Produgs und ihre Verwendung |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| JP5258331B2 (ja) | 2008-03-03 | 2013-08-07 | ロート製薬株式会社 | 光安定性が改善されたニューキノロン系抗菌剤含有医薬組成物 |
| WO2010006072A2 (en) | 2008-07-08 | 2010-01-14 | The Regents Of The University Of California | Mtor modulators and uses thereof |
| EP2318406B1 (en) | 2008-07-17 | 2016-01-27 | Critical Outcome Technologies, Inc. | Thiosemicarbazone inhibitor compounds and cancer treatment methods |
| EP3338770B1 (en) | 2010-03-08 | 2023-06-07 | Sloan-Kettering Institute For Cancer Research | Cdc7 kinase inhibitors and uses thereof |
| EP2554169B1 (en) * | 2010-03-29 | 2019-11-20 | EA Pharma Co., Ltd. | Pharmaceutical preparation comprising phenylalanine derivative |
| US8402515B2 (en) | 2010-05-06 | 2013-03-19 | Jonathan Weizman | Apparatus and method for establishing a peer-to-peer communication session with a client device |
| WO2011146727A1 (en) | 2010-05-19 | 2011-11-24 | Philip Bosch | Methods of treating interstitial cystitis |
| US8709419B2 (en) * | 2010-08-17 | 2014-04-29 | Hoffmann-La Roche, Inc. | Combination therapy |
| BR112013012280B1 (pt) | 2010-11-19 | 2022-01-04 | Ecole Polytechnique Federale De Lausanne | Composto, composição farmacêutica, método de tratamento e método de inibição de uma infecção microbiana |
| WO2013152342A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Anti-cancer mtor inhibitor and anti-androgen combination |
| US8940742B2 (en) | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| US9856320B2 (en) | 2012-05-15 | 2018-01-02 | Bristol-Myers Squibb Company | Cancer immunotherapy by disrupting PD-1/PD-L1 signaling |
| US20140105891A1 (en) | 2012-10-05 | 2014-04-17 | Cerulean Pharma Inc. | Treatment of cancer |
| US9295731B2 (en) | 2013-04-01 | 2016-03-29 | Mark Quang Nguyen | Cleavable drug conjugates, compositions thereof and methods of use |
| JP6855243B2 (ja) | 2014-01-24 | 2021-04-07 | エイアイ・セラピューティクス・インコーポレーテッド | 癌治療のためのアピリモド（ａｐｉｌｉｍｏｄ）組成物 |
| KR20170098812A (ko) | 2014-11-07 | 2017-08-30 | 램 테라퓨틱스, 인코포레이티드 | 신장암의 치료에 사용하기 위한 아필리모드 |
| US20190209576A1 (en) | 2014-11-07 | 2019-07-11 | AI Therapeutics, Inc. | Apilimod for use in the treatment of colorectal cancer |
| KR101761573B1 (ko) | 2014-12-29 | 2017-07-26 | 주식회사 인트론바이오테크놀로지 | 신규한 장출혈성 대장균 박테리오파지 Ｅｓｃ-ＣＨＰ-1 및 이의 장출혈성 대장균 증식 억제 용도 |
| US20180015098A1 (en) | 2015-02-03 | 2018-01-18 | Lam Therapeutics, Inc. | Apilimod compositions and methods for using same |
| US20180078561A1 (en) | 2015-03-31 | 2018-03-22 | Lam Therapeutics, Inc. | Active metabolites of apilimod and uses thereof |
| TWI746449B (zh) | 2015-07-20 | 2021-11-21 | 美商Ａｉ治療公司 | 使用阿吡莫德治療癌症之方法 |
| KR20210029790A (ko) | 2018-07-05 | 2021-03-16 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | PIKfyve 저해제 |
| WO2021051135A1 (en) | 2019-09-12 | 2021-03-18 | AI Therapeutics, Inc. | Pikfyve inhibitors for cancer therapy |
-
2015
- 2015-11-06 KR KR1020177015388A patent/KR20170098812A/ko not_active Ceased
- 2015-11-06 PT PT15795318T patent/PT3215158T/pt unknown
- 2015-11-06 AU AU2015342869A patent/AU2015342869A1/en not_active Abandoned
- 2015-11-06 WO PCT/US2015/059512 patent/WO2016073877A1/en not_active Ceased
- 2015-11-06 JP JP2017543329A patent/JP6705828B2/ja not_active Expired - Fee Related
- 2015-11-06 MX MX2017006015A patent/MX377593B/es active IP Right Grant
- 2015-11-06 PL PL15795318T patent/PL3215158T3/pl unknown
- 2015-11-06 EP EP19171060.7A patent/EP3581184B1/en not_active Not-in-force
- 2015-11-06 HU HUE15795318 patent/HUE044557T2/hu unknown
- 2015-11-06 CN CN201580072608.8A patent/CN107249638B/zh not_active Expired - Fee Related
- 2015-11-06 RU RU2017119065A patent/RU2727802C2/ru active
- 2015-11-06 CA CA2966359A patent/CA2966359A1/en not_active Abandoned
- 2015-11-06 BR BR112017008799A patent/BR112017008799A2/pt not_active Application Discontinuation
- 2015-11-06 ES ES15795318T patent/ES2741399T3/es active Active
- 2015-11-06 US US15/524,844 patent/US10206910B2/en active Active
- 2015-11-06 EP EP15795318.3A patent/EP3215158B1/en not_active Not-in-force
-
2017
- 2017-04-24 IL IL251905A patent/IL251905B/en active IP Right Grant
-
2018
- 2018-12-19 US US16/226,175 patent/US20190201385A1/en not_active Abandoned
-
2019
- 2019-11-26 US US16/695,814 patent/US11166944B2/en not_active Expired - Fee Related
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