JP2017535571A5 - - Google Patents
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- JP2017535571A5 JP2017535571A5 JP2017527714A JP2017527714A JP2017535571A5 JP 2017535571 A5 JP2017535571 A5 JP 2017535571A5 JP 2017527714 A JP2017527714 A JP 2017527714A JP 2017527714 A JP2017527714 A JP 2017527714A JP 2017535571 A5 JP2017535571 A5 JP 2017535571A5
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- JP
- Japan
- Prior art keywords
- composition
- enzyme
- substrate
- item
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 claims description 239
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 98
- 102000004190 Enzymes Human genes 0.000 claims description 88
- 108090000790 Enzymes Proteins 0.000 claims description 88
- 229940088598 enzyme Drugs 0.000 claims description 88
- 239000000758 substrate Substances 0.000 claims description 74
- 239000005445 natural material Substances 0.000 claims description 38
- 206010052428 Wound Diseases 0.000 claims description 33
- 208000027418 Wounds and injury Diseases 0.000 claims description 33
- 230000000694 effects Effects 0.000 claims description 23
- 208000015181 infectious disease Diseases 0.000 claims description 23
- 230000000813 microbial effect Effects 0.000 claims description 19
- 235000012907 honey Nutrition 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 239000000126 substance Substances 0.000 claims description 15
- 102000016938 Catalase Human genes 0.000 claims description 12
- 108010053835 Catalase Proteins 0.000 claims description 12
- 238000006243 chemical reaction Methods 0.000 claims description 12
- 206010048038 Wound infection Diseases 0.000 claims description 9
- 230000000845 anti-microbial effect Effects 0.000 claims description 9
- 239000003814 drug Substances 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 230000001684 chronic effect Effects 0.000 claims description 4
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims description 3
- 230000001580 bacterial effect Effects 0.000 claims description 3
- 238000010899 nucleation Methods 0.000 claims description 3
- 239000004366 Glucose oxidase Substances 0.000 claims description 2
- 108010015776 Glucose oxidase Proteins 0.000 claims description 2
- 206010072170 Skin wound Diseases 0.000 claims description 2
- 230000002255 enzymatic effect Effects 0.000 claims description 2
- 229940116332 glucose oxidase Drugs 0.000 claims description 2
- 235000019420 glucose oxidase Nutrition 0.000 claims description 2
- 241000894007 species Species 0.000 claims description 2
- 125000002353 D-glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims 1
- 102000003992 Peroxidases Human genes 0.000 claims 1
- 108040007629 peroxidase activity proteins Proteins 0.000 claims 1
- 238000000034 method Methods 0.000 description 48
- -1 kit Substances 0.000 description 19
- 239000003125 aqueous solvent Substances 0.000 description 10
- 230000002265 prevention Effects 0.000 description 9
- 244000005700 microbiome Species 0.000 description 7
- 238000013268 sustained release Methods 0.000 description 7
- 239000012730 sustained-release form Substances 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 150000003839 salts Chemical class 0.000 description 5
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 208000027157 chronic rhinosinusitis Diseases 0.000 description 4
- 229960003085 meticillin Drugs 0.000 description 4
- 208000034309 Bacterial disease carrier Diseases 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 201000009890 sinusitis Diseases 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- 241000588626 Acinetobacter baumannii Species 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- 208000037942 Methicillin-resistant Staphylococcus aureus infection Diseases 0.000 description 2
- 102000004316 Oxidoreductases Human genes 0.000 description 2
- 108090000854 Oxidoreductases Proteins 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 201000003883 Cystic fibrosis Diseases 0.000 description 1
- 208000032376 Lung infection Diseases 0.000 description 1
- 239000006057 Non-nutritive feed additive Substances 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 230000032770 biofilm formation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000004067 bulking agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201420856A GB201420856D0 (en) | 2014-11-24 | 2014-11-24 | Prevention and treatment of microbial infections |
| GB1420856.5 | 2014-11-24 | ||
| GBGB1508313.2A GB201508313D0 (en) | 2015-05-14 | 2015-05-14 | Prevention and treatment of microbial infections |
| GB1508313.2 | 2015-05-14 | ||
| GB1509654.8 | 2015-06-03 | ||
| GBGB1509654.8A GB201509654D0 (en) | 2015-06-03 | 2015-06-03 | Prevention and treatment of microbial infections |
| GBGB1511576.9A GB201511576D0 (en) | 2015-07-01 | 2015-07-01 | Prevention and treatment of microbial infections |
| GB1511576.9 | 2015-07-01 | ||
| GB1513047.9 | 2015-07-23 | ||
| GBGB1513047.9A GB201513047D0 (en) | 2015-07-23 | 2015-07-23 | Prevention and treatment of microbial infections |
| GBGB1518252.0A GB201518252D0 (en) | 2015-10-15 | 2015-10-15 | Prevention and treatment of microbial infections |
| GB1518252.0 | 2015-10-15 | ||
| GB1519483.0 | 2015-11-04 | ||
| GBGB1519483.0A GB201519483D0 (en) | 2015-11-04 | 2015-11-04 | Prevention and treatment of microbial infections |
| PCT/GB2015/053584 WO2016083798A1 (en) | 2014-11-24 | 2015-11-24 | Prevention and treatment of microbial infections |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018208688A Division JP2019019141A (ja) | 2014-11-24 | 2018-11-06 | 微生物感染の防止及び治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017535571A JP2017535571A (ja) | 2017-11-30 |
| JP2017535571A5 true JP2017535571A5 (enExample) | 2018-12-20 |
Family
ID=54782769
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017527714A Pending JP2017535571A (ja) | 2014-11-24 | 2015-11-24 | 微生物感染の防止及び治療 |
| JP2018208688A Withdrawn JP2019019141A (ja) | 2014-11-24 | 2018-11-06 | 微生物感染の防止及び治療 |
| JP2020104329A Pending JP2020158526A (ja) | 2014-11-24 | 2020-06-17 | 微生物感染の防止及び治療 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018208688A Withdrawn JP2019019141A (ja) | 2014-11-24 | 2018-11-06 | 微生物感染の防止及び治療 |
| JP2020104329A Pending JP2020158526A (ja) | 2014-11-24 | 2020-06-17 | 微生物感染の防止及び治療 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20170266240A1 (enExample) |
| EP (2) | EP3223833B1 (enExample) |
| JP (3) | JP2017535571A (enExample) |
| CN (1) | CN107847527A (enExample) |
| AU (1) | AU2015352171A1 (enExample) |
| BR (1) | BR112017010808A2 (enExample) |
| CA (1) | CA2968308A1 (enExample) |
| ES (1) | ES2750553T3 (enExample) |
| GB (2) | GB2547402B (enExample) |
| WO (1) | WO2016083798A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6825913B2 (ja) | 2014-04-30 | 2021-02-03 | マトケ・ホールディングス・リミテッド | 抗菌組成物 |
| EP3253424B1 (en) * | 2015-02-03 | 2020-12-09 | Matoke Holdings Limited | Antimicrobial fibers and compositions |
| WO2017131691A1 (en) | 2016-01-28 | 2017-08-03 | Kimberly-Clark Worldwide, Inc. | Anti-adherent composition against dna viruses and method of inhibiting the adherence of dna viruses to a surface |
| EP3442605A1 (en) * | 2016-04-12 | 2019-02-20 | Matoke Holdings Limited | Antimicrobial fibers and compositions |
| BR112018072236A2 (pt) | 2016-05-26 | 2019-02-12 | Kimberly Clark Co | método de inibir micróbios de se ligarem a uma superfície, composição antiaderente para impedir a ligação de micróbios a uma superfície, e, lenço para inibir a fixação de micróbios a uma superfície. |
| JP2019533661A (ja) * | 2016-10-06 | 2019-11-21 | マトケ・ホールディングス・リミテッド | 抗微生物組成物 |
| WO2018065789A1 (en) | 2016-10-06 | 2018-04-12 | Matoke Holdings Limited | Antimicrobial compositions |
| GB201716986D0 (en) * | 2017-10-16 | 2017-11-29 | Matoke Holdings Ltd | Antimicrobial compositions |
| WO2019077336A1 (en) * | 2017-10-16 | 2019-04-25 | Matoke Holdings Limited | DOUBLE DISTRIBUTOR CONTAINING WATER AND ANTIMICROBIAL COMPOSITION |
| GB201805996D0 (en) | 2018-04-11 | 2018-05-23 | Matoke Holdings Ltd | Tissue scaffold |
| WO2020193993A2 (en) | 2019-03-27 | 2020-10-01 | Matoke Holdings Limited | Antimicrobial compositions |
| US20220323490A1 (en) * | 2019-05-23 | 2022-10-13 | Arkema Inc. | Prevention of diseases in honeybees |
| WO2021080631A1 (en) * | 2019-10-24 | 2021-04-29 | Hydrofera, Llc | Wound dressing containing a vacuum pump |
| GB2589863A (en) * | 2019-12-09 | 2021-06-16 | Institute Of Tech Sligo | Antimicrobial composition |
| WO2021186165A1 (en) | 2020-03-16 | 2021-09-23 | Matoke Holdings Limited | Antimicrobial compositions |
| RU2759744C1 (ru) * | 2020-09-07 | 2021-11-17 | Олег Владимирович Емшанов | Способ борьбы с биологическими плёнками |
| GB202106320D0 (en) | 2021-05-04 | 2021-06-16 | Matoke Holdings Ltd | Antimicrobial dressing |
| EP4122477A1 (en) * | 2021-07-21 | 2023-01-25 | Mark Edward Fenzl | Wound honey with a pump dispenser |
| GB202210839D0 (en) | 2022-07-25 | 2022-09-07 | Matoke Holdings Ltd | Antimicrobial compositions |
| GB202309435D0 (en) | 2023-06-22 | 2023-08-09 | Matoke Holdings Ltd | Antimicrobial device |
| WO2025012618A1 (en) | 2023-07-07 | 2025-01-16 | Matoke Holdings Limited | Antimicrobial compositions |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1987893A (en) | 1931-03-26 | 1935-01-15 | Cornell Universlty | Honey process and product |
| JPS58870A (ja) * | 1981-06-20 | 1983-01-06 | Hayashibara Biochem Lab Inc | 飲食物及びその製造方法 |
| US4617190A (en) * | 1984-08-27 | 1986-10-14 | Laclede Professional Products, Inc. | Enzymatic powder milk |
| DK501686A (da) * | 1986-10-20 | 1988-04-21 | Otto Melchior Poulsen | Enzymholdigt, baktericidt middel samt tandplejemidler og saarbehandlingsmidler, som indeholder det |
| US5310541A (en) * | 1992-08-27 | 1994-05-10 | Montgomery Robert E | Antimicrobial rawhide animal chew containing an oxidoreductase and oxidoreductase substrate |
| BE1017155A3 (nl) * | 2006-06-01 | 2008-03-04 | Sanomedical Bvba | Wondverzorgingsproduct. |
| GB0619786D0 (en) * | 2006-10-06 | 2006-11-15 | Inst Of Technology Sligo | An antimicrobial and immunostimulatory system |
| US20100098645A1 (en) * | 2006-10-06 | 2010-04-22 | Institute Of Technology Sligo | Formulation and method for the treatment of fungal nail infections |
| BE1017344A3 (nl) * | 2006-10-27 | 2008-06-03 | Cnci Bvba | Methode voor het steriliseren van ruwe, onverhitte honing, preparaat voor wondverzorging op basis van honing en een wondverzorging behandelingsproduct. |
| PH12012501106A1 (en) * | 2009-12-04 | 2018-02-07 | Colgate Palmolive Co | Non-aqueous single tube dentifrice whitening compositions, methods of use and manufacture thereof |
| AU2010328283A1 (en) * | 2009-12-09 | 2012-06-14 | Kci Licensing, Inc. | Inhibiting bacterial infection and biofilm formation |
| US20130273020A1 (en) * | 2010-08-30 | 2013-10-17 | Comvita New Zealand Limited | Antifungal composition |
| JP6825913B2 (ja) * | 2014-04-30 | 2021-02-03 | マトケ・ホールディングス・リミテッド | 抗菌組成物 |
| FR3020948B1 (fr) * | 2014-05-14 | 2018-04-06 | Melipharm | Composition antimicrobienne |
-
2015
- 2015-11-24 CA CA2968308A patent/CA2968308A1/en not_active Abandoned
- 2015-11-24 US US15/528,969 patent/US20170266240A1/en not_active Abandoned
- 2015-11-24 EP EP15804915.5A patent/EP3223833B1/en active Active
- 2015-11-24 AU AU2015352171A patent/AU2015352171A1/en not_active Abandoned
- 2015-11-24 EP EP19173943.2A patent/EP3603654A1/en not_active Withdrawn
- 2015-11-24 ES ES15804915T patent/ES2750553T3/es active Active
- 2015-11-24 CN CN201580073528.4A patent/CN107847527A/zh active Pending
- 2015-11-24 JP JP2017527714A patent/JP2017535571A/ja active Pending
- 2015-11-24 GB GB1709530.8A patent/GB2547402B/en active Active
- 2015-11-24 WO PCT/GB2015/053584 patent/WO2016083798A1/en not_active Ceased
- 2015-11-24 GB GB1800813.6A patent/GB2554629B8/en active Active
- 2015-11-24 BR BR112017010808A patent/BR112017010808A2/pt not_active Application Discontinuation
-
2018
- 2018-11-06 JP JP2018208688A patent/JP2019019141A/ja not_active Withdrawn
-
2020
- 2020-06-17 JP JP2020104329A patent/JP2020158526A/ja active Pending
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