JP2017533920A5 - - Google Patents
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- Publication number
- JP2017533920A5 JP2017533920A5 JP2017524349A JP2017524349A JP2017533920A5 JP 2017533920 A5 JP2017533920 A5 JP 2017533920A5 JP 2017524349 A JP2017524349 A JP 2017524349A JP 2017524349 A JP2017524349 A JP 2017524349A JP 2017533920 A5 JP2017533920 A5 JP 2017533920A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- situ vaccine
- mosaic virus
- cowpea mosaic
- empty
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000011065 in-situ storage Methods 0.000 claims 10
- 229960005486 vaccine Drugs 0.000 claims 10
- 241000723655 Cowpea mosaic virus Species 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 6
- 239000002105 nanoparticle Substances 0.000 claims 6
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 208000030381 cutaneous melanoma Diseases 0.000 claims 1
- 229960004679 doxorubicin Drugs 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 208000037819 metastatic cancer Diseases 0.000 claims 1
- 208000011575 metastatic malignant neoplasm Diseases 0.000 claims 1
- 201000003708 skin melanoma Diseases 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462076543P | 2014-11-07 | 2014-11-07 | |
| US62/076,543 | 2014-11-07 | ||
| US201562107617P | 2015-01-26 | 2015-01-26 | |
| US62/107,617 | 2015-01-26 | ||
| US201562159389P | 2015-05-11 | 2015-05-11 | |
| US62/159,389 | 2015-05-11 | ||
| PCT/US2015/059675 WO2016073972A1 (en) | 2014-11-07 | 2015-11-09 | Cancer immunotherapy using virus particles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017533920A JP2017533920A (ja) | 2017-11-16 |
| JP2017533920A5 true JP2017533920A5 (Direct) | 2018-11-22 |
| JP6731405B2 JP6731405B2 (ja) | 2020-07-29 |
Family
ID=55909946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017524349A Active JP6731405B2 (ja) | 2014-11-07 | 2015-11-09 | ウイルス粒子を用いた癌免疫療法 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10639363B2 (Direct) |
| EP (2) | EP3215520B1 (Direct) |
| JP (1) | JP6731405B2 (Direct) |
| CN (1) | CN107001428B (Direct) |
| AU (1) | AU2015342790B2 (Direct) |
| CA (1) | CA2967336C (Direct) |
| WO (2) | WO2016073972A1 (Direct) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10086095B2 (en) | 2012-10-09 | 2018-10-02 | Case Western Reserve University | Rod-shaped plant virus nanoparticles as imaging agent platforms |
| US11193111B2 (en) | 2013-01-17 | 2021-12-07 | Case Western Reserve University | Viral nanoparticle multimers |
| US11998594B2 (en) | 2014-04-02 | 2024-06-04 | Case Western Reserve University | Anti-cancer plant virus particles linked to HER2 antigens |
| US9925281B2 (en) | 2014-08-05 | 2018-03-27 | Case Western Reserve University | Coated plant virus imaging agents |
| JP6731405B2 (ja) | 2014-11-07 | 2020-07-29 | ケース ウエスタン リザーブ ユニバーシティ | ウイルス粒子を用いた癌免疫療法 |
| US12465624B2 (en) | 2018-05-08 | 2025-11-11 | Case Western Reserve University | Cancer immunotherapy using virus particles and immune checkpoint therapy |
| US11617787B2 (en) | 2014-11-07 | 2023-04-04 | Case Western Reserve University | Cancer immunotherapy using virus particles |
| EP3313527B1 (en) | 2015-06-29 | 2021-02-24 | Case Western Reserve University | Anticancer drug-containing plant virus particles |
| WO2017011826A1 (en) | 2015-07-16 | 2017-01-19 | Case Western Reserve University | Plant virus particles for delivery of antimitotic agents |
| WO2018017985A1 (en) | 2016-07-21 | 2018-01-25 | Case Western Reserve University | Plant virus or virus-like particle constructs |
| US12433840B2 (en) | 2016-11-03 | 2025-10-07 | Case Western Reserve University | Melt processed viral nanoparticle constructs |
| CA3042695A1 (en) | 2016-11-03 | 2018-05-11 | Case Western Reserve University | Melt processed viral nanoparticle constructs |
| US11590183B2 (en) | 2017-03-10 | 2023-02-28 | Case Western Reserve University | Cancer immunotherapy using virus particles |
| WO2018213587A1 (en) | 2017-05-17 | 2018-11-22 | Case Western Reserve University | Anticancer trail-targeted plant virus particles |
| WO2019084555A1 (en) | 2017-10-27 | 2019-05-02 | Case Western Reserve University | TYMOVIRUS VIRUSES AND VIRAL TYPE PARTICLES USEFUL AS NANOVECTORS FOR IMAGING AND THERAPEUTIC AGENTS |
| WO2019173487A1 (en) * | 2018-03-06 | 2019-09-12 | University Of Louisville Research Foundation, Inc. | Methods for treatment of cancer and enhancement of nanoparticle accumulation in tissues |
| WO2020139978A1 (en) * | 2018-12-27 | 2020-07-02 | Verimmune Llc | Conjugated virus-like particles and uses thereof as anti-tumor immune redirectors |
| US20220145316A1 (en) * | 2019-03-01 | 2022-05-12 | The Regents Of The University Of California | Cancer immunotherapy |
| US11390853B2 (en) | 2019-04-26 | 2022-07-19 | Case Western Reserve University | Freeze dried viral nanoparticle constructs |
| US11896676B2 (en) | 2019-08-07 | 2024-02-13 | Case Western Reserve University | Targeting cancer cells and tissue using filamentous plant virus particles |
| CN110859861A (zh) * | 2019-12-04 | 2020-03-06 | 武汉工程大学 | 植物病原微生物杀灭癌细胞或艾滋病病毒的用途 |
| US11529430B2 (en) | 2019-12-20 | 2022-12-20 | Case Western Reserve University | Polydopamine decorated tobacco mosaic theranostic virus nanoparticles |
| US12203073B2 (en) | 2019-12-20 | 2025-01-21 | Case Western Reserve University | Plant viral RNA delivery nanoparticles and uses thereof |
| WO2022150648A1 (en) * | 2021-01-08 | 2022-07-14 | The Regents Of The University Of California | Ovarian cancer vaccine |
| EP4449427A1 (en) | 2021-12-15 | 2024-10-23 | Diamante S.r.l. | Apparatus for determining administrative form of a composition of an engineered virus-based nanoparticle for a treatment of an autoimmune condition |
| CA3248669A1 (en) * | 2022-01-19 | 2023-07-27 | Universitat Bern | COMPOSITIONS OF VIRUS-TYPE PARTICLES AND MICROCRYSTALLINE TYROSINE |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5004606A (en) | 1986-09-24 | 1991-04-02 | Hybritech Incorporated | Non-covalent antibody-anthracycline immunocomplexes |
| GB9921337D0 (en) * | 1999-09-09 | 1999-11-10 | Axis Genetics Plc | Modified plant viruses |
| GB9924351D0 (en) * | 1999-10-14 | 1999-12-15 | Brennan Frank | Immunomodulation methods and compositions |
| ES2593304T3 (es) | 2002-05-02 | 2016-12-07 | Wyeth Holdings Llc | Conjugados de transportador derivado de caliqueamicina |
| CA2435632A1 (en) * | 2003-07-21 | 2005-01-21 | Warren Hugh Finlay | Formulation of powder containing nanoparticles for aerosol delivery to the lung |
| KR20070058426A (ko) | 2004-06-02 | 2007-06-08 | 사이토스 바이오테크놀로지 아게 | 비-인간 ｔｎｆ-펩티드의 담체 콘쥬게이트의 의학적 용도 |
| WO2008048288A2 (en) | 2005-11-09 | 2008-04-24 | Montana State University | Novel nanoparticles and use thereof |
| CN101495137A (zh) * | 2005-12-02 | 2009-07-29 | 陶氏环球技术公司 | 新植物病毒颗粒及其灭活方法 |
| US7771339B2 (en) * | 2006-05-31 | 2010-08-10 | Ab Mimator | Method and system for radiotherapy treatment |
| WO2009045579A2 (en) | 2007-06-14 | 2009-04-09 | The Regents Of The University Of California | Multimodal imaging probes for in vivo targeted and non-targeted imaging and therapeutics |
| WO2016149264A1 (en) | 2015-03-18 | 2016-09-22 | The Johns Hopkins University | Compositions and methods for sensitizing cells to trail-induced apoptosis |
| ATE539148T1 (de) * | 2009-11-30 | 2012-01-15 | United Cancer Res Inst | Neuer klon des geflügelpestvirus, herstellung und anwendung bei der medizinischen behandlung von krebs |
| US20130236491A1 (en) | 2010-12-09 | 2013-09-12 | Iosif Grigorievich Atabekov | Spherical nano and microparticles derived from plant viruses for the display of foreign proteins or epitopes |
| US9486834B2 (en) | 2011-07-29 | 2016-11-08 | Youtec Co., Ltd. | Ferroelectric film and method for manufacturing the same |
| WO2013158620A1 (en) | 2012-04-16 | 2013-10-24 | North Carolina State University | Nanotechnology system for agricultural applications |
| WO2013163337A1 (en) | 2012-04-24 | 2013-10-31 | The Ohio State University | Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome |
| US10232057B2 (en) | 2012-05-31 | 2019-03-19 | Case Western Reserve University | Targeting cancer cells and tissue using filamentous plant virus particles |
| US10086095B2 (en) | 2012-10-09 | 2018-10-02 | Case Western Reserve University | Rod-shaped plant virus nanoparticles as imaging agent platforms |
| WO2016019393A1 (en) | 2014-08-01 | 2016-02-04 | Gpb Scientific, Llc | Methods and systems for processing particles |
| EP3046565A4 (en) * | 2013-09-19 | 2017-06-28 | Folia Biotech Inc. | Papaya mosaic virus and virus-like particles in cancer therapy |
| WO2015188110A1 (en) | 2014-06-05 | 2015-12-10 | The Johns Hopkins University | Reversible pegylation for screeing of therapeutic proteins in vivo |
| US9925281B2 (en) | 2014-08-05 | 2018-03-27 | Case Western Reserve University | Coated plant virus imaging agents |
| JP6731405B2 (ja) * | 2014-11-07 | 2020-07-29 | ケース ウエスタン リザーブ ユニバーシティ | ウイルス粒子を用いた癌免疫療法 |
| EP3313527B1 (en) * | 2015-06-29 | 2021-02-24 | Case Western Reserve University | Anticancer drug-containing plant virus particles |
| WO2017011826A1 (en) | 2015-07-16 | 2017-01-19 | Case Western Reserve University | Plant virus particles for delivery of antimitotic agents |
| WO2018213587A1 (en) | 2017-05-17 | 2018-11-22 | Case Western Reserve University | Anticancer trail-targeted plant virus particles |
-
2015
- 2015-11-09 JP JP2017524349A patent/JP6731405B2/ja active Active
- 2015-11-09 CN CN201580063662.6A patent/CN107001428B/zh active Active
- 2015-11-09 AU AU2015342790A patent/AU2015342790B2/en active Active
- 2015-11-09 EP EP15857504.3A patent/EP3215520B1/en active Active
- 2015-11-09 WO PCT/US2015/059675 patent/WO2016073972A1/en not_active Ceased
- 2015-11-09 EP EP21201960.8A patent/EP3957644B1/en active Active
- 2015-11-09 CA CA2967336A patent/CA2967336C/en active Active
-
2017
- 2017-05-08 US US15/589,677 patent/US10639363B2/en active Active
-
2018
- 2018-05-08 WO PCT/US2018/031661 patent/WO2018208828A1/en not_active Ceased
-
2020
- 2020-04-17 US US16/851,778 patent/US11260121B2/en active Active
-
2022
- 2022-02-25 US US17/680,813 patent/US11730803B2/en active Active
-
2023
- 2023-08-22 US US18/236,676 patent/US12350326B2/en active Active
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