JP2017533200A5 - - Google Patents
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- Publication number
- JP2017533200A5 JP2017533200A5 JP2017521550A JP2017521550A JP2017533200A5 JP 2017533200 A5 JP2017533200 A5 JP 2017533200A5 JP 2017521550 A JP2017521550 A JP 2017521550A JP 2017521550 A JP2017521550 A JP 2017521550A JP 2017533200 A5 JP2017533200 A5 JP 2017533200A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- ring
- independently
- alkoxy
- aryb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C[C@]([C@]([C@](C)C=C(C)[C@@](C)([C@]12)[C@](C[C@@]3OC)C=C[C@]1C1(C4)C24[C@](*)[C@@](C)[C@]1OC(c1ccc[n]1)=O)OC3=O)OC(CCC[N+]1(CC2)CCN2CC1)=O Chemical compound C[C@]([C@]([C@](C)C=C(C)[C@@](C)([C@]12)[C@](C[C@@]3OC)C=C[C@]1C1(C4)C24[C@](*)[C@@](C)[C@]1OC(c1ccc[n]1)=O)OC3=O)OC(CCC[N+]1(CC2)CCN2CC1)=O 0.000 description 7
- FXDUWLKXJFKJFB-QACCSKINSA-N C[C@H]([C@H]([C@H](C)/C=C(\C)/[C@@]1([C@@H](C[C@@H]2OC)C=CC([C@@H]3[C@@H](C4C)OC(c5ccc[n]5C)=O)C1C3[C@@H]4O)O)OC2=O)OC([n]1nnnc1N)=O Chemical compound C[C@H]([C@H]([C@H](C)/C=C(\C)/[C@@]1([C@@H](C[C@@H]2OC)C=CC([C@@H]3[C@@H](C4C)OC(c5ccc[n]5C)=O)C1C3[C@@H]4O)O)OC2=O)OC([n]1nnnc1N)=O FXDUWLKXJFKJFB-QACCSKINSA-N 0.000 description 1
- NPVHKHQNFQJSEL-PNSQNNTDSA-N C[C@H]([C@](C)([C@H](C)/C=C(\C)/[C@@](C)(C1[C@@H]([C@@H](C)C2)[O](C)=C)[C@](C[C@@H]3OC)(C=C)C=CC1C2=O)OC3=O)OC(C(OCC1=CCCC=C1)=O)=O Chemical compound C[C@H]([C@](C)([C@H](C)/C=C(\C)/[C@@](C)(C1[C@@H]([C@@H](C)C2)[O](C)=C)[C@](C[C@@H]3OC)(C=C)C=CC1C2=O)OC3=O)OC(C(OCC1=CCCC=C1)=O)=O NPVHKHQNFQJSEL-PNSQNNTDSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2014/089204 | 2014-10-22 | ||
| PCT/CN2014/089204 WO2016061772A1 (en) | 2014-10-22 | 2014-10-22 | Nargenicin compounds and uses thereof as antibacterial agents |
| PCT/US2015/056627 WO2016064982A1 (en) | 2014-10-22 | 2015-10-21 | Nargenicin compounds and uses thereof as antibacterial agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017533200A JP2017533200A (ja) | 2017-11-09 |
| JP2017533200A5 true JP2017533200A5 (https=) | 2019-10-17 |
Family
ID=55760063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017521550A Pending JP2017533200A (ja) | 2014-10-22 | 2015-10-21 | ナルゲニシン化合物及び抗菌剤としてのそれの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9944654B2 (https=) |
| EP (1) | EP3209667B1 (https=) |
| JP (1) | JP2017533200A (https=) |
| KR (1) | KR20170070197A (https=) |
| CN (1) | CN107108646A (https=) |
| AU (1) | AU2015335992A1 (https=) |
| BR (1) | BR112017008101A2 (https=) |
| CA (1) | CA2964377A1 (https=) |
| MX (1) | MX2017005271A (https=) |
| RU (1) | RU2017117253A (https=) |
| WO (2) | WO2016061772A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016061772A1 (en) | 2014-10-22 | 2016-04-28 | Merck Sharp & Dohme Corp. | Nargenicin compounds and uses thereof as antibacterial agents |
| KR102440647B1 (ko) | 2020-07-28 | 2022-09-06 | 선문대학교 산학협력단 | 나르제니신 a1 유도체를 포함하는 항혈관신생용 조성물 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4148883A (en) | 1977-08-18 | 1979-04-10 | Pfizer Inc. | Antibiotics produced by new species of nocardia |
| US4360683A (en) * | 1980-08-06 | 1982-11-23 | The Upjohn Company | Antibiotic nodusmicin derivatives |
| US4351769A (en) * | 1980-08-25 | 1982-09-28 | The Upjohn Company | Antibiotic composition of matter |
| US4448970A (en) * | 1981-02-19 | 1984-05-15 | The Upjohn Company | Nargenicin derivatives |
| US4436747A (en) | 1982-10-21 | 1984-03-13 | Pfizer Inc. | Nargenicin C1 |
| US4605624A (en) * | 1982-10-21 | 1986-08-12 | Pfizer Inc. | Nocardia species capable of producing nargenicin C1 |
| ES2258234T3 (es) | 2002-08-12 | 2006-08-16 | PHARMACIA & UPJOHN COMPANY LLC | N-aril-2-oxazolidinonas y sus derivados. |
| GB0227701D0 (en) | 2002-11-28 | 2003-01-08 | Astrazeneca Ab | Chemical compounds |
| MXPA05005522A (es) | 2002-11-28 | 2005-07-25 | Astrazeneca Ab | Oxazolidinonas como agentes antibacterianos. |
| WO2005012270A2 (en) | 2003-07-29 | 2005-02-10 | Rib-X Pharmaceuticals, Inc. | Biaryl heterocyclic amines, amides, and sulfur-containing compounds and methods of making and using the same |
| KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| JP2008500318A (ja) | 2004-05-25 | 2008-01-10 | アストラゼネカ アクチボラグ | 抗菌剤としての３−｛４−（ピリジン−３−イル）フェニル｝−５−（１ｈ−１，２，３−トリアゾール−１−イルメチル）−１，３−オキサゾリジン−２−オン |
| WO2007133803A2 (en) | 2006-05-15 | 2007-11-22 | Rib-X Pharmaceuticals, Inc. | Treatment of mycobacterial infections |
| WO2008069619A1 (en) | 2006-12-08 | 2008-06-12 | Legochem Bioscience Ltd. | Novel oxazolidinone derivatives, process for preparing thereof and pharmaceutical composition containing the same |
| KR101040468B1 (ko) | 2008-02-29 | 2011-06-09 | 조선대학교산학협력단 | 새로운 노카르디아 속 균주 및 그의 발효 배양물의 용도 |
| KR101022564B1 (ko) | 2008-12-19 | 2011-03-16 | 조선대학교산학협력단 | 나르제니신을 포함하는 염증성 신경퇴행성 질환의 치료용 제약 조성물 |
| WO2011139832A2 (en) | 2010-04-28 | 2011-11-10 | Rib-X Pharmaceuticals, Inc. | Method for treating mycobacterial infections |
| KR101561964B1 (ko) | 2013-11-15 | 2015-10-20 | 한국과학기술연구원 | 옥사졸리디논 화합물 및 이를 포함하는 c형 간염 예방 또는 치료용 약학 조성물 |
| WO2016061772A1 (en) | 2014-10-22 | 2016-04-28 | Merck Sharp & Dohme Corp. | Nargenicin compounds and uses thereof as antibacterial agents |
-
2014
- 2014-10-22 WO PCT/CN2014/089204 patent/WO2016061772A1/en not_active Ceased
-
2015
- 2015-10-21 CA CA2964377A patent/CA2964377A1/en not_active Abandoned
- 2015-10-21 BR BR112017008101A patent/BR112017008101A2/pt not_active Application Discontinuation
- 2015-10-21 KR KR1020177013260A patent/KR20170070197A/ko not_active Withdrawn
- 2015-10-21 AU AU2015335992A patent/AU2015335992A1/en not_active Abandoned
- 2015-10-21 JP JP2017521550A patent/JP2017533200A/ja active Pending
- 2015-10-21 US US15/517,570 patent/US9944654B2/en active Active
- 2015-10-21 WO PCT/US2015/056627 patent/WO2016064982A1/en not_active Ceased
- 2015-10-21 CN CN201580069971.4A patent/CN107108646A/zh active Pending
- 2015-10-21 MX MX2017005271A patent/MX2017005271A/es unknown
- 2015-10-21 EP EP15853228.3A patent/EP3209667B1/en active Active
- 2015-10-21 RU RU2017117253A patent/RU2017117253A/ru not_active Application Discontinuation
-
2018
- 2018-03-02 US US15/910,571 patent/US10144741B2/en active Active