JP2017531646A5 - - Google Patents
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- JP2017531646A5 JP2017531646A5 JP2017518070A JP2017518070A JP2017531646A5 JP 2017531646 A5 JP2017531646 A5 JP 2017531646A5 JP 2017518070 A JP2017518070 A JP 2017518070A JP 2017518070 A JP2017518070 A JP 2017518070A JP 2017531646 A5 JP2017531646 A5 JP 2017531646A5
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- Japan
- Prior art keywords
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14003389.5 | 2014-10-01 | ||
| EP14003389 | 2014-10-01 | ||
| PCT/EP2015/001973 WO2016050358A1 (en) | 2014-10-01 | 2015-10-01 | Boronic acid derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531646A JP2017531646A (ja) | 2017-10-26 |
| JP2017531646A5 true JP2017531646A5 (cg-RX-API-DMAC7.html) | 2019-10-17 |
| JP6662865B2 JP6662865B2 (ja) | 2020-03-11 |
Family
ID=51751859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017518070A Active JP6662865B2 (ja) | 2014-10-01 | 2015-10-01 | ボロン酸誘導体 |
Country Status (21)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2017115193A (ru) | 2014-10-01 | 2018-11-06 | Мерк Патент Гмбх | Производные бороновой кислоты |
| JP6835711B2 (ja) | 2014-10-01 | 2021-02-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | ボロン酸誘導体 |
| US9453018B2 (en) | 2014-10-01 | 2016-09-27 | Bristol-Myers Squibb Company | Pyrimidinones as factor XIa inhibitors |
| KR20170062518A (ko) | 2014-10-01 | 2017-06-07 | 메르크 파텐트 게엠베하 | 보론산 유도체 |
| PT3571208T (pt) | 2017-01-18 | 2021-04-13 | Principia Biopharma Inc | Inibidores do imunoproteassoma |
| DK3672977T3 (da) | 2017-08-24 | 2022-09-26 | Merck Patent Gmbh | Boronsyrederivater |
| TW201912624A (zh) * | 2017-08-29 | 2019-04-01 | 大陸商浙江海正藥業股份有限公司 | (E)-α,β-不飽和醯胺化合物及其製備方法和用途 |
| WO2019075386A1 (en) * | 2017-10-13 | 2019-04-18 | The Regents Of The University Of California | MODULATORS OF MTORC1 |
| MX2020005046A (es) * | 2017-11-16 | 2020-08-20 | Principia Biopharma Inc | Inhibidores de inmunoproteasoma. |
| RS63666B1 (sr) | 2017-11-16 | 2022-11-30 | Principia Biopharma Inc | Inhibitori imunoproteazoma |
| BR112021001359A2 (pt) | 2018-07-26 | 2021-04-20 | Merck Patent Gmbh | derivados de ácido borônico |
| CN113135943A (zh) * | 2020-01-19 | 2021-07-20 | 首药控股(北京)有限公司 | 硼酸衍生物 |
| CN113135944A (zh) * | 2020-01-19 | 2021-07-20 | 首药控股(北京)有限公司 | 硼酸衍生物 |
| JP2024529468A (ja) | 2021-07-29 | 2024-08-06 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規の［（１ｒ）－２－（１－ベンゾフラン－３－イル）－１－｛［（１ｓ，２ｒ，４ｒ）－７－オキサビシクロ［２．２．１］ヘプタン－２－イル］ホルムアミド｝エチル］ボロン酸の結晶性形態、その付加物、および得るためのプロセス |
| JP7734276B2 (ja) * | 2021-10-14 | 2025-09-04 | ショウヤオ ホールディングス（ベイジン） カンパニー， リミテッド | ボロン酸誘導体 |
| WO2023232830A1 (en) | 2022-06-02 | 2023-12-07 | Merck Patent Gmbh | Boronic acid adducts |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5658885A (en) * | 1993-04-27 | 1997-08-19 | The Dupont Merck Pharmaceutical Company | Amidino and guanidino substituted boronic acid inhibitors of trypsin-like enzymes |
| US5462964A (en) * | 1993-10-20 | 1995-10-31 | The Du Pont Merck Pharmaceutical Company | Dipeptide boronic acid inhibitors of trypsin-like enzymes |
| IL111175A0 (en) * | 1993-10-07 | 1994-12-29 | Du Pont Merck Pharma | Electrophilic peptide analogs as inhibitors of trypsin-like serine proteases and pharmaceutical compositions containing them |
| CA2376965A1 (en) * | 1999-07-07 | 2001-01-11 | Timothy Patrick Forsyth | Peptide boronic acid inhibitors of hepatitis c virus protease |
| CN100447151C (zh) * | 2002-09-09 | 2008-12-31 | 特里根有限公司 | 硼酸盐及其在制备治疗血栓形成药物中的应用 |
| CN1867572B (zh) * | 2003-08-14 | 2012-03-28 | 赛福伦公司 | 蛋白酶体抑制剂及其使用方法 |
| US7576206B2 (en) * | 2003-08-14 | 2009-08-18 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
| AR075090A1 (es) * | 2008-09-29 | 2011-03-09 | Millennium Pharm Inc | Derivados de acido 1-amino-2-ciclobutiletilboronico inhibidores de proteosoma,utiles como agentes anticancerigenos, y composiciones farmaceuticas que los comprenden. |
| RU2586219C2 (ru) * | 2010-04-22 | 2016-06-10 | Марс, Инкорпорейтед | Ингибиторы аргиназы и их терапевтические применения |
| JP6129203B2 (ja) | 2011-12-22 | 2017-05-17 | アレス トレーディング ソシエテ アノニム | α−アミノボロン酸誘導体、選択性免疫プロテアソーム阻害剤 |
| SG10201908467RA (en) | 2014-01-31 | 2019-10-30 | Bristol Myers Squibb Co | Macrocycles with hetrocyclic p2' groups as factor xia inhibitors |
| NO2721243T3 (cg-RX-API-DMAC7.html) | 2014-10-01 | 2018-10-20 | ||
| KR102478309B1 (ko) | 2014-10-01 | 2022-12-15 | 얀센 파마슈티칼즈, 인코포레이티드 | 뎅기 바이러스 복제 억제제로서의 １치환 또는 ２치환 인돌 |
| PT3201176T (pt) | 2014-10-01 | 2019-03-04 | Janssen Pharmaceuticals Inc | Derivados indol mono- ou dissubstituídos como inibidores da replicação viral do dengue |
| KR20170062518A (ko) | 2014-10-01 | 2017-06-07 | 메르크 파텐트 게엠베하 | 보론산 유도체 |
| RU2017115193A (ru) | 2014-10-01 | 2018-11-06 | Мерк Патент Гмбх | Производные бороновой кислоты |
| JP6835711B2 (ja) | 2014-10-01 | 2021-02-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | ボロン酸誘導体 |
-
2015
- 2015-10-01 RU RU2017115192A patent/RU2717558C2/ru active
- 2015-10-01 ES ES15778613T patent/ES2761774T3/es active Active
- 2015-10-01 SG SG11201702628XA patent/SG11201702628XA/en unknown
- 2015-10-01 EP EP15778613.8A patent/EP3201206B1/en active Active
- 2015-10-01 DK DK15778613.8T patent/DK3201206T3/da active
- 2015-10-01 CN CN201580053501.9A patent/CN107001391B/zh active Active
- 2015-10-01 US US15/516,427 patent/US10669289B2/en active Active
- 2015-10-01 CA CA2963203A patent/CA2963203A1/en active Pending
- 2015-10-01 MY MYPI2017701058A patent/MY186911A/en unknown
- 2015-10-01 MX MX2017003999A patent/MX372823B/es active IP Right Grant
- 2015-10-01 NZ NZ730981A patent/NZ730981A/en unknown
- 2015-10-01 KR KR1020177011562A patent/KR102457840B1/ko active Active
- 2015-10-01 AU AU2015327345A patent/AU2015327345B9/en active Active
- 2015-10-01 BR BR112017006622-0A patent/BR112017006622A2/pt not_active Application Discontinuation
- 2015-10-01 UA UAA201704168A patent/UA122672C2/uk unknown
- 2015-10-01 WO PCT/EP2015/001973 patent/WO2016050358A1/en not_active Ceased
- 2015-10-01 JP JP2017518070A patent/JP6662865B2/ja active Active
-
2017
- 2017-02-16 PH PH12017500293A patent/PH12017500293A1/en unknown
- 2017-03-21 IL IL251302A patent/IL251302B/en active IP Right Grant
- 2017-03-31 CL CL2017000792A patent/CL2017000792A1/es unknown
- 2017-04-28 ZA ZA2017/03007A patent/ZA201703007B/en unknown
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