JP2017530127A5 - - Google Patents
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- Publication number
- JP2017530127A5 JP2017530127A5 JP2017516166A JP2017516166A JP2017530127A5 JP 2017530127 A5 JP2017530127 A5 JP 2017530127A5 JP 2017516166 A JP2017516166 A JP 2017516166A JP 2017516166 A JP2017516166 A JP 2017516166A JP 2017530127 A5 JP2017530127 A5 JP 2017530127A5
- Authority
- JP
- Japan
- Prior art keywords
- nrg
- ventricular
- pharmaceutical preparation
- treating
- mammal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410529437.4A CN105497876B (zh) | 2014-09-24 | 2014-09-24 | 神经调节蛋白用于预防、治疗或延迟心脏室性心律失常的方法和组合物 |
| CN201410529437.4 | 2014-09-24 | ||
| PCT/CN2015/088972 WO2016045493A1 (zh) | 2014-09-24 | 2015-09-06 | 神经调节蛋白预防、治疗或延迟室性心律失常的用途及其组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017530127A JP2017530127A (ja) | 2017-10-12 |
| JP2017530127A5 true JP2017530127A5 (https=) | 2018-09-27 |
Family
ID=55580273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017516166A Pending JP2017530127A (ja) | 2014-09-24 | 2015-09-06 | 心室性不整脈の予防、治療、又は遅延におけるニューレグリンの使用、及びその組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10441633B2 (https=) |
| EP (1) | EP3199174B1 (https=) |
| JP (1) | JP2017530127A (https=) |
| KR (1) | KR20170055492A (https=) |
| CN (2) | CN105497876B (https=) |
| AU (1) | AU2015320230B2 (https=) |
| CA (1) | CA2961813A1 (https=) |
| RU (1) | RU2017113775A (https=) |
| WO (1) | WO2016045493A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5738516B2 (ja) | 2005-12-30 | 2015-06-24 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド | 心機能改善のためのニューレグリンの徐放 |
| JP6096262B2 (ja) | 2009-08-25 | 2017-03-15 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． | ニューレグリンに基づく心不全の治療方法 |
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| US10894815B2 (en) | 2012-10-08 | 2021-01-19 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Compositions and methods for treating heart failure in diabetic patients |
| RU2015154737A (ru) | 2013-05-22 | 2017-06-27 | Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи, Ко., Лтд. | Пролонгированное высвобождение нейрегулина для лечения сердечной недостаточности |
| CN104758922A (zh) | 2014-01-03 | 2015-07-08 | 上海泽生科技开发有限公司 | 纽兰格林制剂的配方 |
| CN105561298A (zh) | 2014-10-17 | 2016-05-11 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
| EP3836913A4 (en) * | 2018-08-14 | 2022-05-18 | Emory University | Inducing proliferation of cardiomyocytes and therapeutic uses related thereto |
| AR121035A1 (es) | 2019-04-01 | 2022-04-13 | Lilly Co Eli | Compuestos de neuregulina-4 y métodos de uso |
| AU2020348436A1 (en) * | 2019-09-16 | 2022-04-07 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Recombinant human neuregulin derivatives and use thereof |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7115554B1 (en) | 1993-05-06 | 2006-10-03 | Acorda Therapeutics, Inc. | Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III |
| US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
| US5716930A (en) | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
| US5834229A (en) | 1991-05-24 | 1998-11-10 | Genentech, Inc. | Nucleic acids vectors and host cells encoding and expressing heregulin 2-α |
| US5912326A (en) | 1995-09-08 | 1999-06-15 | President And Fellows Of Harvard College | Cerebellum-derived growth factors |
| JP2001519400A (ja) | 1997-10-14 | 2001-10-23 | ケンブリッジ ニューロサイエンス インク． | ニューレグリン使用を含む治療法 |
| AUPP785098A0 (en) | 1998-12-21 | 1999-01-21 | Victor Chang Cardiac Research Institute, The | Treatment of heart disease |
| US6635249B1 (en) | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
| CN1138785C (zh) | 1999-06-04 | 2004-02-18 | 周明东 | 生长因子神经调节蛋白及其类似物的新应用 |
| AUPQ105799A0 (en) | 1999-06-18 | 1999-07-08 | Victor Chang Cardiac Research Institute, The | Cell growth inhibition |
| CN1498656A (zh) * | 2002-11-08 | 2004-05-26 | 上海泽生科技开发有限公司 | 神经调节蛋白用于心肌梗死治疗的方法和组合物 |
| WO2003099320A1 (en) * | 2002-05-24 | 2003-12-04 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
| BRPI0606484A2 (pt) | 2005-01-20 | 2009-06-30 | Janssen Pharmaceutica Nv | métodos para controle do intervalo qt |
| US20070213264A1 (en) | 2005-12-02 | 2007-09-13 | Mingdong Zhou | Neuregulin variants and methods of screening and using thereof |
| JP5738516B2 (ja) | 2005-12-30 | 2015-06-24 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド | 心機能改善のためのニューレグリンの徐放 |
| US9580515B2 (en) | 2006-08-21 | 2017-02-28 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neukinase, a downstream protein of neuregulin |
| CN101310766B (zh) * | 2007-05-25 | 2014-04-16 | 上海泽生科技开发有限公司 | 神经调节蛋白的新用途 |
| US20090156488A1 (en) | 2007-09-12 | 2009-06-18 | Zensun (Shanghai) Science & Technology Limited | Use of neuregulin for organ preservation |
| US8603817B2 (en) * | 2008-11-03 | 2013-12-10 | University Of Washington | Induction of human embryonic stem cell derived cardiac pacemaker or chamber-type cardiomyocytes by manipulation of neuregulin signaling |
| JP2012509908A (ja) | 2008-11-28 | 2012-04-26 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド | ニューレグリン及び心臓幹細胞 |
| JP5743898B2 (ja) | 2008-11-28 | 2015-07-01 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド | ニューレグリンペプチド及びその使用 |
| EP3087998B1 (en) | 2009-06-09 | 2019-09-04 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neuregulin based methods for treating heart failure |
| CN102470161A (zh) | 2009-06-09 | 2012-05-23 | 上海泽生科技开发有限公司 | 神经调节蛋白用于治疗心力衰竭的有效剂量 |
| CN102139095A (zh) | 2010-01-29 | 2011-08-03 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏缺血再灌注损伤的方法和组合物 |
| US9029328B2 (en) * | 2010-03-24 | 2015-05-12 | The Brigham And Women's Hospital, Inc. | Methods for cardioprotection and cardioregeneration with dimers of EGF family ligands |
| US20120028992A1 (en) * | 2010-08-02 | 2012-02-02 | Brown Arthur M | Pharmaceutical compositions for terminating acute episodes of cardiac arrhythmia, restoring sinus rhythm, preventing recurrence of cardiac arrhythmia and/or maintaining normal sinus rhythm in mammals |
| WO2012054718A2 (en) | 2010-10-22 | 2012-04-26 | The General Hospital Corporation | Treating long qt syndrome |
| CN102302552A (zh) * | 2011-08-31 | 2012-01-04 | 朱明军 | 一种治疗心律失常的胶囊及其制备方法 |
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| US10894815B2 (en) | 2012-10-08 | 2021-01-19 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Compositions and methods for treating heart failure in diabetic patients |
| RU2015154737A (ru) | 2013-05-22 | 2017-06-27 | Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи, Ко., Лтд. | Пролонгированное высвобождение нейрегулина для лечения сердечной недостаточности |
| KR20160035061A (ko) | 2013-08-01 | 2016-03-30 | 길리애드 사이언시즈, 인코포레이티드 | 긴 qt 증후군을 치료하기 위한 화합물 및 방법 |
| CN104758300A (zh) | 2014-01-02 | 2015-07-08 | 上海泽生科技开发有限公司 | 维生素d及其组合物的抗菌用途 |
| CN104758922A (zh) | 2014-01-03 | 2015-07-08 | 上海泽生科技开发有限公司 | 纽兰格林制剂的配方 |
| CN105561298A (zh) | 2014-10-17 | 2016-05-11 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
-
2014
- 2014-09-24 CN CN201410529437.4A patent/CN105497876B/zh active Active
-
2015
- 2015-09-06 CA CA2961813A patent/CA2961813A1/en not_active Abandoned
- 2015-09-06 KR KR1020177008203A patent/KR20170055492A/ko not_active Withdrawn
- 2015-09-06 WO PCT/CN2015/088972 patent/WO2016045493A1/zh not_active Ceased
- 2015-09-06 JP JP2017516166A patent/JP2017530127A/ja active Pending
- 2015-09-06 US US15/513,939 patent/US10441633B2/en active Active
- 2015-09-06 RU RU2017113775A patent/RU2017113775A/ru not_active Application Discontinuation
- 2015-09-06 EP EP15845381.1A patent/EP3199174B1/en not_active Revoked
- 2015-09-06 CN CN201580050316.4A patent/CN110337304A/zh active Pending
- 2015-09-06 AU AU2015320230A patent/AU2015320230B2/en active Active
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